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The map label for this gene is qseB [H]

Identifier: 120608754

GI number: 120608754

Start: 47920

End: 48633

Strand: Direct

Name: qseB [H]

Synonym: Aave_0041

Alternate gene names: 120608754

Gene position: 47920-48633 (Clockwise)

Preceding gene: 120608748

Following gene: 120608755

Centisome position: 0.9

GC content: 71.57

Gene sequence:

>714_bases
ATGCGGATTCTCGTAGTCGAAGACGATGCCGTGTTGCGCGGCGTGATGCAGCGCAGCCTGGCCGATGCGGGCCACCGCGT
GGACGTGGCCGCCACGCTGGCCGAGGCCGACCATTTCTGGAAGGTGCAGCCTTTCGATGCGGTGCTGCTGGACCTGAACC
TGCCGCAGGATGCCGCCCATGCCAGCCCGGTGGGCAGCGGCCTGGCCGTGCTGCGCGCCGCCCGCGCGCGCGGTGACCGC
ACGCCGGTGCTGGTGCTCACCGCCCGCGACCGCACCGAGGAGCGCATCGCCGGCCTGGATGCGGGCGCCGACGACTACCT
GGGCAAGCCCTTCGATCTGGCCGAGGTGGAAGCCCGGCTGCGCGCCCTGGTGCGCCGCACGCAGGGCACGGACGATCGCA
CCAGCGCCGGCACGCTGGTGCTGGACCGGCGGGTGCGCCGCTTCACCCTGCATGGCCAGCCCTTCGACCTGCCTGCGCGC
GAGTTCGAGGTGCTGTGGGAGCTGATGACCCCGCCCGGGCGGGTGGTGAGCAAGCGCAGCCTGTCGGACAAGCTGTCGGA
CTTCGATGACATGCTGGGCGACAACGCGCTGGAAGCCTTCATCTCGCGCCTGCGCAAGAAGCTGCAGGGCAGCGGCGCCG
GCATCCGCACGCTGCGCGGGCTGGGCTACATGCTGGAGGCGACCGACGCCTCCGCGACGCAAGGGGATGCATGA

Upstream 100 bases:

>100_bases
AATGCGGCTTGTGGGCCACGGTGCGGCTGGCCGTATCCGGACGCGGCTTTTTTCTCTTTCTTTTTTCTTTTTCTTTCCTT
CCCTTTCTGGTGCAGCACCC

Downstream 100 bases:

>100_bases
GCGGCGGTACGCCTGCCGCGGCCCTGCCGCAGAGGCCGGCCCCCTCGCCGCCCTCGCTGCGTGCACGCCTGTTGCGCCAT
GTGCTGGTACCACTGGCGCT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MRILVVEDDAVLRGVMQRSLADAGHRVDVAATLAEADHFWKVQPFDAVLLDLNLPQDAAHASPVGSGLAVLRAARARGDR
TPVLVLTARDRTEERIAGLDAGADDYLGKPFDLAEVEARLRALVRRTQGTDDRTSAGTLVLDRRVRRFTLHGQPFDLPAR
EFEVLWELMTPPGRVVSKRSLSDKLSDFDDMLGDNALEAFISRLRKKLQGSGAGIRTLRGLGYMLEATDASATQGDA

Sequences:

>Translated_237_residues
MRILVVEDDAVLRGVMQRSLADAGHRVDVAATLAEADHFWKVQPFDAVLLDLNLPQDAAHASPVGSGLAVLRAARARGDR
TPVLVLTARDRTEERIAGLDAGADDYLGKPFDLAEVEARLRALVRRTQGTDDRTSAGTLVLDRRVRRFTLHGQPFDLPAR
EFEVLWELMTPPGRVVSKRSLSDKLSDFDDMLGDNALEAFISRLRKKLQGSGAGIRTLRGLGYMLEATDASATQGDA
>Mature_237_residues
MRILVVEDDAVLRGVMQRSLADAGHRVDVAATLAEADHFWKVQPFDAVLLDLNLPQDAAHASPVGSGLAVLRAARARGDR
TPVLVLTARDRTEERIAGLDAGADDYLGKPFDLAEVEARLRALVRRTQGTDDRTSAGTLVLDRRVRRFTLHGQPFDLPAR
EFEVLWELMTPPGRVVSKRSLSDKLSDFDDMLGDNALEAFISRLRKKLQGSGAGIRTLRGLGYMLEATDASATQGDA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. Currently it is not known whether this effect is direct or not [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=42.4778761061947, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=36.2445414847162, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=37.3390557939914, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786784, Length=235, Percent_Identity=31.4893617021277, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=31.063829787234, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=32.618025751073, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=27.8260869565217, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788394, Length=232, Percent_Identity=30.6034482758621, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=32.15859030837, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1787229, Length=241, Percent_Identity=33.195020746888, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI2367329, Length=175, Percent_Identity=35.4285714285714, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=32.1739130434783, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790863, Length=241, Percent_Identity=27.8008298755187, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI145693140, Length=241, Percent_Identity=29.8755186721992, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=136, Percent_Identity=32.3529411764706, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25899; Mature: 25899

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVVEDDAVLRGVMQRSLADAGHRVDVAATLAEADHFWKVQPFDAVLLDLNLPQDAAH
CEEEEECCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHCEEECCCCEEEEECCCCCCHHH
ASPVGSGLAVLRAARARGDRTPVLVLTARDRTEERIAGLDAGADDYLGKPFDLAEVEARL
CCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHCCCCCCHHHCCCCCCHHHHHHHH
RALVRRTQGTDDRTSAGTLVLDRRVRRFTLHGQPFDLPAREFEVLWELMTPPGRVVSKRS
HHHHHHHCCCCCCCCCCHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHH
LSDKLSDFDDMLGDNALEAFISRLRKKLQGSGAGIRTLRGLGYMLEATDASATQGDA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECCCCCCCCCC
>Mature Secondary Structure
MRILVVEDDAVLRGVMQRSLADAGHRVDVAATLAEADHFWKVQPFDAVLLDLNLPQDAAH
CEEEEECCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHCEEECCCCEEEEECCCCCCHHH
ASPVGSGLAVLRAARARGDRTPVLVLTARDRTEERIAGLDAGADDYLGKPFDLAEVEARL
CCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHCCCCCCHHHCCCCCCHHHHHHHH
RALVRRTQGTDDRTSAGTLVLDRRVRRFTLHGQPFDLPAREFEVLWELMTPPGRVVSKRS
HHHHHHHCCCCCCCCCCHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHH
LSDKLSDFDDMLGDNALEAFISRLRKKLQGSGAGIRTLRGLGYMLEATDASATQGDA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]