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The map label for this gene is luxS

Identifier: 119946976

GI number: 119946976

Start: 4164164

End: 4164673

Strand: Reverse

Name: luxS

Synonym: Ping_3371

Alternate gene names: 119946976

Gene position: 4164673-4164164 (Counterclockwise)

Preceding gene: 119946977

Following gene: 119946973

Centisome position: 91.34

GC content: 44.12

Gene sequence:

>510_bases
ATGCCATTATTAGATAGTTTTACCGTTGATCATACGATTATGAATGCCCCTGCGGTTCGCATAGCGAAGACCATGCAAAC
CCCGAGCAAAGATACGATCACCGTCTTTGATTTGCGTTTTACGGTGCCCAATGAAGATCTCTTGTCGGAAAAAGGGATCC
ATACCCTAGAGCATCTTTATGCGGGATTTATGCGCAATCATTTAAATAGCCCTGATGTTGAAATTATTGATATTTCACCC
ATGGGTTGTCGAACTGGATTTTATATGAGTTTGATTGGGAGCCCAAGTGAGACTGAGGTTGCCAATGCCTGGTTGGCCGC
GATGCGTGATGTGTTAGCTGTAGAGCATCAGGAAGAGATTCCTGAGCTTAATAAGTACCAATGCGGGACTTATGCGATGC
ACTCGCTTGCTGAGGCAAAAACCATTGCTCAAGCGGTTATTGATGCCGGCGTCGGCACTAATAAAAATGCAGATATCACC
TTATCGGATGAACAATTAAAGCAGCTTTAA

Upstream 100 bases:

>100_bases
GACAATTAAAAACCTGTCAGGACAATTTAGATTCCAGTTGGTTATGGCGGTTATTTTTTACTTAACCGTTGATTAAATAT
ATTTTTAAAAAGGAGTTCCA

Downstream 100 bases:

>100_bases
GCGCTGCCGTTAATTGAAGAATACGAATATAGCAATCTAGATTGTTATATTCGTATAAAAAGTAGTAGCGCTGTTATTAT
GGATTATCAGGACAGACTAT

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MPLLDSFTVDHTIMNAPAVRIAKTMQTPSKDTITVFDLRFTVPNEDLLSEKGIHTLEHLYAGFMRNHLNSPDVEIIDISP
MGCRTGFYMSLIGSPSETEVANAWLAAMRDVLAVEHQEEIPELNKYQCGTYAMHSLAEAKTIAQAVIDAGVGTNKNADIT
LSDEQLKQL

Sequences:

>Translated_169_residues
MPLLDSFTVDHTIMNAPAVRIAKTMQTPSKDTITVFDLRFTVPNEDLLSEKGIHTLEHLYAGFMRNHLNSPDVEIIDISP
MGCRTGFYMSLIGSPSETEVANAWLAAMRDVLAVEHQEEIPELNKYQCGTYAMHSLAEAKTIAQAVIDAGVGTNKNADIT
LSDEQLKQL
>Mature_168_residues
PLLDSFTVDHTIMNAPAVRIAKTMQTPSKDTITVFDLRFTVPNEDLLSEKGIHTLEHLYAGFMRNHLNSPDVEIIDISPM
GCRTGFYMSLIGSPSETEVANAWLAAMRDVLAVEHQEEIPELNKYQCGTYAMHSLAEAKTIAQAVIDAGVGTNKNADITL
SDEQLKQL

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=169, Percent_Identity=68.0473372781065, Blast_Score=250, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_PSYIN (A1SZZ2)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944656.1
- ProteinModelPortal:   A1SZZ2
- SMR:   A1SZZ2
- STRING:   A1SZZ2
- GeneID:   4625682
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_3371
- eggNOG:   COG1854
- HOGENOM:   HBG347473
- OMA:   VRIAKTM
- PhylomeDB:   A1SZZ2
- ProtClustDB:   PRK02260
- BioCyc:   PING357804:PING_3371-MONOMER
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 18663; Mature: 18532

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFTVDHTIMNAPAVRIAKTMQTPSKDTITVFDLRFTVPNEDLLSEKGIHTLEHLY
CCCCCCCCCCHHHHCCCHHHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHCCHHHHHHHH
AGFMRNHLNSPDVEIIDISPMGCRTGFYMSLIGSPSETEVANAWLAAMRDVLAVEHQEEI
HHHHHHHCCCCCEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHC
PELNKYQCGTYAMHSLAEAKTIAQAVIDAGVGTNKNADITLSDEQLKQL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHCC
>Mature Secondary Structure 
PLLDSFTVDHTIMNAPAVRIAKTMQTPSKDTITVFDLRFTVPNEDLLSEKGIHTLEHLY
CCCCCCCCCHHHHCCCHHHHHHHHCCCCCCEEEEEEEEEECCCHHHHHHCCHHHHHHHH
AGFMRNHLNSPDVEIIDISPMGCRTGFYMSLIGSPSETEVANAWLAAMRDVLAVEHQEEI
HHHHHHHCCCCCEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHC
PELNKYQCGTYAMHSLAEAKTIAQAVIDAGVGTNKNADITLSDEQLKQL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA