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The map label for this gene is hflK [H]

Identifier: 119946842

GI number: 119946842

Start: 3992620

End: 3993792

Strand: Reverse

Name: hflK [H]

Synonym: Ping_3236

Alternate gene names: 119946842

Gene position: 3993792-3992620 (Counterclockwise)

Preceding gene: 119946843

Following gene: 119946841

Centisome position: 87.59

GC content: 41.18

Gene sequence:

>1173_bases
ATGGCTTGGAACGAACCGGGAAAAGATAAAGACCCGTGGAAAAACAATGATAAAAAGAAAGATCAGGGACCGCCTGATCT
TGATGTCGTTTTCCAGAAATTATCAAAATTACTCGGTGGTTTGTTTGGTAAAAAGCCTTCTTCAGACGACAGCGGCAATA
AGGGTGGCGGTAATATTGCCATTATTGCCGTGTTTGCAATAATTGCTATTGTTTGGTTTGTCAGTGGTTGGTATACGATT
AAAGAATCTGATCGTGGTGTCGTATTACGTTTTGGTGCTTACCATTCTCAAGTTGAAGCGGGTTTGCATTGGAATCCGAA
GTTTATTGATCAAATTATTCCGATTAACGTTGAAGCATTTCGTACTATGCCAACAACGGGGTTCATGCTGACGGAAGATG
AAAATATTGTTAAGGTTGGCATGGAAGTGCAGTACCGTATTATTGCACCTGAAAAATACCTGTTTAGTGTCACTAATGCG
GATAACAGTTTATTACAAGCATTAGATAGTTCATTGCGTTTTGTTGTTGGTCATTCGACTATGGATGATGTGTTAACAAC
AGGCCGTGAAGTGGTGCGCCAGGAAACATGGGTAATGATCGACGATATTATCGAATCATACGATTTAGGTATCGATGTTG
TGGATGTTAACTTACAACAAACACGTCCGCCTGAAGAAGTTAAAGATGCCTTTGATGATGCTATTGCCGCGCAGGAAGAT
GAACAGCGTTTTATACGTGAAGCTGAAGCTTATGAACGTGAAAAAGCACCGATCGCTCGTGGTCAAGTAAAACGTATTGA
ACAGCAGGCCCTAGCTTATAAAGAAGGTCTTATTTTAAAAGCGCAGGGTGAAGTTGCCCGTTTTAATCAATTATTACCTC
AATATCAAGCCAACCCTGAAGTGACTCGTCAACGTCTCTATCTGGAAACCATGGAAAAGGTATTGGATAGCACCTCTAAA
GTGCTTATTGATAATAATGCTGGTGGTAATTTAACTTTTCTTCCATTGGATAAATTGATGGGCGGAAGCACAGATAAAGT
AGGGCTGGATAAAAGTGTTTCAGAAATTGAAACACGTTCACGTGCCGATGAAAAAGCAGACCAAGATGAACGAGCGGGCG
GAACTACTTCGCCGAGTCGTAGTAGTAACAGAAGCTCTGGGAGAGACTACTAA

Upstream 100 bases:

>100_bases
AATCAACTCACCGCATATTATGTCATGTTTTCTTTATTATTCGAGAGAACATTGCTACATTGCTTAACACTTTTTTGTAT
TATTAAATCGGGAGCTATAT

Downstream 100 bases:

>100_bases
TGAATAAATTATTAATACTTCCAGTACTGATTATTGCGATGCTTTTCAGCAGCGCATTTGTTATCACGGAAGGGCAGCAT
GGAATAGTAATGCAATTTAG

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MAWNEPGKDKDPWKNNDKKKDQGPPDLDVVFQKLSKLLGGLFGKKPSSDDSGNKGGGNIAIIAVFAIIAIVWFVSGWYTI
KESDRGVVLRFGAYHSQVEAGLHWNPKFIDQIIPINVEAFRTMPTTGFMLTEDENIVKVGMEVQYRIIAPEKYLFSVTNA
DNSLLQALDSSLRFVVGHSTMDDVLTTGREVVRQETWVMIDDIIESYDLGIDVVDVNLQQTRPPEEVKDAFDDAIAAQED
EQRFIREAEAYEREKAPIARGQVKRIEQQALAYKEGLILKAQGEVARFNQLLPQYQANPEVTRQRLYLETMEKVLDSTSK
VLIDNNAGGNLTFLPLDKLMGGSTDKVGLDKSVSEIETRSRADEKADQDERAGGTTSPSRSSNRSSGRDY

Sequences:

>Translated_390_residues
MAWNEPGKDKDPWKNNDKKKDQGPPDLDVVFQKLSKLLGGLFGKKPSSDDSGNKGGGNIAIIAVFAIIAIVWFVSGWYTI
KESDRGVVLRFGAYHSQVEAGLHWNPKFIDQIIPINVEAFRTMPTTGFMLTEDENIVKVGMEVQYRIIAPEKYLFSVTNA
DNSLLQALDSSLRFVVGHSTMDDVLTTGREVVRQETWVMIDDIIESYDLGIDVVDVNLQQTRPPEEVKDAFDDAIAAQED
EQRFIREAEAYEREKAPIARGQVKRIEQQALAYKEGLILKAQGEVARFNQLLPQYQANPEVTRQRLYLETMEKVLDSTSK
VLIDNNAGGNLTFLPLDKLMGGSTDKVGLDKSVSEIETRSRADEKADQDERAGGTTSPSRSSNRSSGRDY
>Mature_389_residues
AWNEPGKDKDPWKNNDKKKDQGPPDLDVVFQKLSKLLGGLFGKKPSSDDSGNKGGGNIAIIAVFAIIAIVWFVSGWYTIK
ESDRGVVLRFGAYHSQVEAGLHWNPKFIDQIIPINVEAFRTMPTTGFMLTEDENIVKVGMEVQYRIIAPEKYLFSVTNAD
NSLLQALDSSLRFVVGHSTMDDVLTTGREVVRQETWVMIDDIIESYDLGIDVVDVNLQQTRPPEEVKDAFDDAIAAQEDE
QRFIREAEAYEREKAPIARGQVKRIEQQALAYKEGLILKAQGEVARFNQLLPQYQANPEVTRQRLYLETMEKVLDSTSKV
LIDNNAGGNLTFLPLDKLMGGSTDKVGLDKSVSEIETRSRADEKADQDERAGGTTSPSRSSNRSSGRDY

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=385, Percent_Identity=51.4285714285714, Blast_Score=348, Evalue=4e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 43597; Mature: 43465

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWNEPGKDKDPWKNNDKKKDQGPPDLDVVFQKLSKLLGGLFGKKPSSDDSGNKGGGNIA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
IIAVFAIIAIVWFVSGWYTIKESDRGVVLRFGAYHSQVEAGLHWNPKFIDQIIPINVEAF
HHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCHHHHHHCCCCCCHHHHHHHCCCCHHHH
RTMPTTGFMLTEDENIVKVGMEVQYRIIAPEKYLFSVTNADNSLLQALDSSLRFVVGHST
CCCCCCCEEEECCCCEEEECCEEEEEEECCCEEEEEEECCCHHHHHHHHHHHEEEECCCH
MDDVLTTGREVVRQETWVMIDDIIESYDLGIDVVDVNLQQTRPPEEVKDAFDDAIAAQED
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHH
EQRFIREAEAYEREKAPIARGQVKRIEQQALAYKEGLILKAQGEVARFNQLLPQYQANPE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCHH
VTRQRLYLETMEKVLDSTSKVLIDNNAGGNLTFLPLDKLMGGSTDKVGLDKSVSEIETRS
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEHHHHHCCCCCCCCCCCHHHHHHHHH
RADEKADQDERAGGTTSPSRSSNRSSGRDY
HHHHHCCCHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AWNEPGKDKDPWKNNDKKKDQGPPDLDVVFQKLSKLLGGLFGKKPSSDDSGNKGGGNIA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
IIAVFAIIAIVWFVSGWYTIKESDRGVVLRFGAYHSQVEAGLHWNPKFIDQIIPINVEAF
HHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCHHHHHHCCCCCCHHHHHHHCCCCHHHH
RTMPTTGFMLTEDENIVKVGMEVQYRIIAPEKYLFSVTNADNSLLQALDSSLRFVVGHST
CCCCCCCEEEECCCCEEEECCEEEEEEECCCEEEEEEECCCHHHHHHHHHHHEEEECCCH
MDDVLTTGREVVRQETWVMIDDIIESYDLGIDVVDVNLQQTRPPEEVKDAFDDAIAAQED
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHH
EQRFIREAEAYEREKAPIARGQVKRIEQQALAYKEGLILKAQGEVARFNQLLPQYQANPE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCHH
VTRQRLYLETMEKVLDSTSKVLIDNNAGGNLTFLPLDKLMGGSTDKVGLDKSVSEIETRS
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEHHHHHCCCCCCCCCCCHHHHHHHHH
RADEKADQDERAGGTTSPSRSSNRSSGRDY
HHHHHCCCHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]