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The map label for this gene is hflC [H]

Identifier: 119946841

GI number: 119946841

Start: 3991754

End: 3992620

Strand: Reverse

Name: hflC [H]

Synonym: Ping_3235

Alternate gene names: 119946841

Gene position: 3992620-3991754 (Counterclockwise)

Preceding gene: 119946842

Following gene: 119946840

Centisome position: 87.57

GC content: 40.6

Gene sequence:

>867_bases
ATGAATAAATTATTAATACTTCCAGTACTGATTATTGCGATGCTTTTCAGCAGCGCATTTGTTATCACGGAAGGGCAGCA
TGGAATAGTAATGCAATTTAGTAAAGTTAAACGTGATGCAGCGGGTGATCCTGTTGCTTATCCGCCTGGCTTACACTTTA
AAATTCCTTTTATTGATTCCGTGCGCAGCATGGACACGCGTATCCAAACCTTGGATGATAAAGCAGATCGCTTTGTGACT
TCTGAGAAAAAAGATTTAATCATCGACTCTTACGTGAAATGGCAGATTGATGATTTAGCGGTTTACTTTTTGGCAACAGG
CGGCAATAAAATGCAGGCTGAATCCTTACTTAAGCGTAAAATTAATAATGGATTACGCAGTGAGATAGGTTCGCATACTA
TTACCGATATTGTCTCGGGTAAACGTGGTCAAGTGATGGAAACAGCACTGAAACGTATGGCTCGTTCAAGTGAATTAGGT
ATTAAGGTTGTTGATGTTCGGATCAAAAGAATCAATCTACCTGACGAAGTCAGCAACAGTGTTTACAAACGGATGCGTGC
TGAGCGATTAGCAGTAGCAAAAGAGCATCGCTCTAAAGGTCAAGAGCAATCAGAAGTCATTCGCGCTAATATTGACCGGA
AAGTCTCTATCATGCTCGCCCAAGCTAATAAAGAATCTTTGGAGATTCGCGGGGTGGGTGATGCTGAGTCTTCACAAATA
TATGGCGACTCTTATTCACAAGATGCTGAATTCTTCTCTTTTTTACGCAGTATGAAAGCGTATGAGAAAAGTTTTACAGG
GAAAGATGATGTCATGGTGTTAAGCCCGGACTCGGACTTCTTTAAGTACATGAACAACAAAGATTAA

Upstream 100 bases:

>100_bases
CACGTTCACGTGCCGATGAAAAAGCAGACCAAGATGAACGAGCGGGCGGAACTACTTCGCCGAGTCGTAGTAGTAACAGA
AGCTCTGGGAGAGACTACTA

Downstream 100 bases:

>100_bases
TTTTATTTTTCTTATTGAAAAAGGGCGGTTTACCGCCCTTTTTTGTGTCCTCAATAAAGCCGTAAATGGGTTAGTTCGTA
AAGATCTGAACATCGTGCTT

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MNKLLILPVLIIAMLFSSAFVITEGQHGIVMQFSKVKRDAAGDPVAYPPGLHFKIPFIDSVRSMDTRIQTLDDKADRFVT
SEKKDLIIDSYVKWQIDDLAVYFLATGGNKMQAESLLKRKINNGLRSEIGSHTITDIVSGKRGQVMETALKRMARSSELG
IKVVDVRIKRINLPDEVSNSVYKRMRAERLAVAKEHRSKGQEQSEVIRANIDRKVSIMLAQANKESLEIRGVGDAESSQI
YGDSYSQDAEFFSFLRSMKAYEKSFTGKDDVMVLSPDSDFFKYMNNKD

Sequences:

>Translated_288_residues
MNKLLILPVLIIAMLFSSAFVITEGQHGIVMQFSKVKRDAAGDPVAYPPGLHFKIPFIDSVRSMDTRIQTLDDKADRFVT
SEKKDLIIDSYVKWQIDDLAVYFLATGGNKMQAESLLKRKINNGLRSEIGSHTITDIVSGKRGQVMETALKRMARSSELG
IKVVDVRIKRINLPDEVSNSVYKRMRAERLAVAKEHRSKGQEQSEVIRANIDRKVSIMLAQANKESLEIRGVGDAESSQI
YGDSYSQDAEFFSFLRSMKAYEKSFTGKDDVMVLSPDSDFFKYMNNKD
>Mature_288_residues
MNKLLILPVLIIAMLFSSAFVITEGQHGIVMQFSKVKRDAAGDPVAYPPGLHFKIPFIDSVRSMDTRIQTLDDKADRFVT
SEKKDLIIDSYVKWQIDDLAVYFLATGGNKMQAESLLKRKINNGLRSEIGSHTITDIVSGKRGQVMETALKRMARSSELG
IKVVDVRIKRINLPDEVSNSVYKRMRAERLAVAKEHRSKGQEQSEVIRANIDRKVSIMLAQANKESLEIRGVGDAESSQI
YGDSYSQDAEFFSFLRSMKAYEKSFTGKDDVMVLSPDSDFFKYMNNKD

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=310, Percent_Identity=48.7096774193548, Blast_Score=302, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 32504; Mature: 32504

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLLILPVLIIAMLFSSAFVITEGQHGIVMQFSKVKRDAAGDPVAYPPGLHFKIPFIDS
CCCEEHHHHHHHHHHHCCEEEEECCCCCEEEEHHHHHHHCCCCCCCCCCCCEEECCHHHH
VRSMDTRIQTLDDKADRFVTSEKKDLIIDSYVKWQIDDLAVYFLATGGNKMQAESLLKRK
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHEEEECCEEEEEEECCCCHHHHHHHHHHH
INNGLRSEIGSHTITDIVSGKRGQVMETALKRMARSSELGIKVVDVRIKRINLPDEVSNS
HCCHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCHHHHHH
VYKRMRAERLAVAKEHRSKGQEQSEVIRANIDRKVSIMLAQANKESLEIRGVGDAESSQI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCCCCCC
YGDSYSQDAEFFSFLRSMKAYEKSFTGKDDVMVLSPDSDFFKYMNNKD
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHCCCCC
>Mature Secondary Structure
MNKLLILPVLIIAMLFSSAFVITEGQHGIVMQFSKVKRDAAGDPVAYPPGLHFKIPFIDS
CCCEEHHHHHHHHHHHCCEEEEECCCCCEEEEHHHHHHHCCCCCCCCCCCCEEECCHHHH
VRSMDTRIQTLDDKADRFVTSEKKDLIIDSYVKWQIDDLAVYFLATGGNKMQAESLLKRK
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHEEEECCEEEEEEECCCCHHHHHHHHHHH
INNGLRSEIGSHTITDIVSGKRGQVMETALKRMARSSELGIKVVDVRIKRINLPDEVSNS
HCCHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCHHHHHH
VYKRMRAERLAVAKEHRSKGQEQSEVIRANIDRKVSIMLAQANKESLEIRGVGDAESSQI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCCCCCC
YGDSYSQDAEFFSFLRSMKAYEKSFTGKDDVMVLSPDSDFFKYMNNKD
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]