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The map label for this gene is intA [H]

Identifier: 119945317

GI number: 119945317

Start: 1956483

End: 1957733

Strand: Reverse

Name: intA [H]

Synonym: Ping_1601

Alternate gene names: 119945317

Gene position: 1957733-1956483 (Counterclockwise)

Preceding gene: 119945318

Following gene: 119945316

Centisome position: 42.94

GC content: 40.53

Gene sequence:

>1251_bases
ATGGCAGTAAAAGTAATTCCCCTAACTGATAAGAAAATTAACTCAGCAAAGATTCACGATAAAGATTATGTATTATCTGA
TGGTGATGGATTACAGCTAAGAGTGAGATCTAATGGTTCTAAAATCTGGAACTTCAACTACAAACACCCACAAACAAAAA
AACGTATTAATATTAATATTGGTAAATACCCAGGTGTTGCATTACTTAATGCACGTAAAAAAGCATTGAGTTATCGTGAT
CTTCTGGCACAAGATATTGACCCTAAAGAAAACAGGGAAAAAAAATTAGCAGAAGATAAAAAAATCACTGAACACACAGT
GAAAAATGTCGCATTAGAATGGTATGAACTAAAAAAACATTCAGTAACGGCTGATTATGCCACTGATATTTGGCGCTCCT
TAGATCGTCATATCTTCCCCCTCCTTGAAAACACCCCCATATCCTCGGTTACAGCCCCAATGGTCATCGATCTATTAAGG
CCGATAGAAGCAAAAGGCAGCTTAGAAACAGTTAAACGCCTTACTCAACGTTTAAATGAAATTATGACCTACGCCGTCAA
TGGCGGTTTAATCTTTGCTAATCCGTTAAGTGGCATCAAAGCTAATTTCAAAAAACCTAAAAAATCACACATGCTCGCCC
TAACACCTGACGAACTGCCTGAATTGATGATGACCATTGCCAATGCCAGCATCAAGAGAACAACACGCTGCTTGATTGAA
TGGCAACTTCATACCATGACCCGCCCTTCTGAAAGTGCCGGTGCAAAATGGGAAGAGATTGATATTGAAGCTAAAACATG
GACTATTCCACCTGAACGTATGAAGAAACGCCGTGAACATGTGGTGCCATTGACGGATCAAGCTCTGACACTACTTGAAA
CGATGCGTCCAATCAGTGGACATAGAGAATATCTTTTCCCATCAGACCGCAACCCAAGAACTCATGCTAATAGCGAAACG
GCCAATACTGCTTTAAGACGCATGAATTTTGGTGGCCGTTTAGTGAGTCATGGATTACGTTCAATCGCCAGTACCACACT
TAATGAACAAGGCTTTGAAGCTGACCTAGTGGAAGCAGCTCTGGCACATGTCGGTGATAATCAAGTGCGTAATGCTTATA
ACCGGACTGATTATCTGGAACGCAGAAGACCAATGATGTACTGGTGGAGCGAGCATATTGAAAAAGCATCACAGGGAAAC
CTGTCTGTTACTGGGTTTAAAAGCTTAAAAGTAATAGGTGACAACTTCTAG

Upstream 100 bases:

>100_bases
GGCGTCTACCAGCAGCTACGAATAATGGTATTCCATAAGGTATTCCAAATAAATCCTGTTATAATTTGGAATACCATTCT
TAGCTATTTGCAGGTAAATC

Downstream 100 bases:

>100_bases
TCACCTATTCGCTTACGGGAAATAACAAACGATTAATGCTTACAATTGCATACGTTAATTATAATTACGCAACAATTAAG
GTAATAGTGTGAATAAAAAA

Product: phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MAVKVIPLTDKKINSAKIHDKDYVLSDGDGLQLRVRSNGSKIWNFNYKHPQTKKRININIGKYPGVALLNARKKALSYRD
LLAQDIDPKENREKKLAEDKKITEHTVKNVALEWYELKKHSVTADYATDIWRSLDRHIFPLLENTPISSVTAPMVIDLLR
PIEAKGSLETVKRLTQRLNEIMTYAVNGGLIFANPLSGIKANFKKPKKSHMLALTPDELPELMMTIANASIKRTTRCLIE
WQLHTMTRPSESAGAKWEEIDIEAKTWTIPPERMKKRREHVVPLTDQALTLLETMRPISGHREYLFPSDRNPRTHANSET
ANTALRRMNFGGRLVSHGLRSIASTTLNEQGFEADLVEAALAHVGDNQVRNAYNRTDYLERRRPMMYWWSEHIEKASQGN
LSVTGFKSLKVIGDNF

Sequences:

>Translated_416_residues
MAVKVIPLTDKKINSAKIHDKDYVLSDGDGLQLRVRSNGSKIWNFNYKHPQTKKRININIGKYPGVALLNARKKALSYRD
LLAQDIDPKENREKKLAEDKKITEHTVKNVALEWYELKKHSVTADYATDIWRSLDRHIFPLLENTPISSVTAPMVIDLLR
PIEAKGSLETVKRLTQRLNEIMTYAVNGGLIFANPLSGIKANFKKPKKSHMLALTPDELPELMMTIANASIKRTTRCLIE
WQLHTMTRPSESAGAKWEEIDIEAKTWTIPPERMKKRREHVVPLTDQALTLLETMRPISGHREYLFPSDRNPRTHANSET
ANTALRRMNFGGRLVSHGLRSIASTTLNEQGFEADLVEAALAHVGDNQVRNAYNRTDYLERRRPMMYWWSEHIEKASQGN
LSVTGFKSLKVIGDNF
>Mature_415_residues
AVKVIPLTDKKINSAKIHDKDYVLSDGDGLQLRVRSNGSKIWNFNYKHPQTKKRININIGKYPGVALLNARKKALSYRDL
LAQDIDPKENREKKLAEDKKITEHTVKNVALEWYELKKHSVTADYATDIWRSLDRHIFPLLENTPISSVTAPMVIDLLRP
IEAKGSLETVKRLTQRLNEIMTYAVNGGLIFANPLSGIKANFKKPKKSHMLALTPDELPELMMTIANASIKRTTRCLIEW
QLHTMTRPSESAGAKWEEIDIEAKTWTIPPERMKKRREHVVPLTDQALTLLETMRPISGHREYLFPSDRNPRTHANSETA
NTALRRMNFGGRLVSHGLRSIASTTLNEQGFEADLVEAALAHVGDNQVRNAYNRTDYLERRRPMMYWWSEHIEKASQGNL
SVTGFKSLKVIGDNF

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=413, Percent_Identity=50.8474576271186, Blast_Score=442, Evalue=1e-125,
Organism=Escherichia coli, GI145693166, Length=400, Percent_Identity=33.5, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1788690, Length=393, Percent_Identity=30.7888040712468, Blast_Score=189, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 47498; Mature: 47367

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKVIPLTDKKINSAKIHDKDYVLSDGDGLQLRVRSNGSKIWNFNYKHPQTKKRININI
CEEEEEECCCCCCCCCEECCCCEEEECCCCEEEEEECCCCEEEEECCCCCCCCCEEEEEE
GKYPGVALLNARKKALSYRDLLAQDIDPKENREKKLAEDKKITEHTVKNVALEWYELKKH
CCCCCEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVTADYATDIWRSLDRHIFPLLENTPISSVTAPMVIDLLRPIEAKGSLETVKRLTQRLNE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
IMTYAVNGGLIFANPLSGIKANFKKPKKSHMLALTPDELPELMMTIANASIKRTTRCLIE
HHHHHCCCCEEEECCCCCHHHCCCCCCCCCEEEECHHHHHHHHHHHHCCHHHHHHHHHEE
WQLHTMTRPSESAGAKWEEIDIEAKTWTIPPERMKKRREHVVPLTDQALTLLETMRPISG
EEEHHCCCCCHHHCCCEEEEEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
HREYLFPSDRNPRTHANSETANTALRRMNFGGRLVSHGLRSIASTTLNEQGFEADLVEAA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LAHVGDNQVRNAYNRTDYLERRRPMMYWWSEHIEKASQGNLSVTGFKSLKVIGDNF
HHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCEEEEECCCC
>Mature Secondary Structure 
AVKVIPLTDKKINSAKIHDKDYVLSDGDGLQLRVRSNGSKIWNFNYKHPQTKKRININI
EEEEEECCCCCCCCCEECCCCEEEECCCCEEEEEECCCCEEEEECCCCCCCCCEEEEEE
GKYPGVALLNARKKALSYRDLLAQDIDPKENREKKLAEDKKITEHTVKNVALEWYELKKH
CCCCCEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVTADYATDIWRSLDRHIFPLLENTPISSVTAPMVIDLLRPIEAKGSLETVKRLTQRLNE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
IMTYAVNGGLIFANPLSGIKANFKKPKKSHMLALTPDELPELMMTIANASIKRTTRCLIE
HHHHHCCCCEEEECCCCCHHHCCCCCCCCCEEEECHHHHHHHHHHHHCCHHHHHHHHHEE
WQLHTMTRPSESAGAKWEEIDIEAKTWTIPPERMKKRREHVVPLTDQALTLLETMRPISG
EEEHHCCCCCHHHCCCEEEEEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
HREYLFPSDRNPRTHANSETANTALRRMNFGGRLVSHGLRSIASTTLNEQGFEADLVEAA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LAHVGDNQVRNAYNRTDYLERRRPMMYWWSEHIEKASQGNLSVTGFKSLKVIGDNF
HHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]