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The map label for this gene is pgsA [H]

Identifier: 119944947

GI number: 119944947

Start: 1487910

End: 1488461

Strand: Direct

Name: pgsA [H]

Synonym: Ping_1194

Alternate gene names: 119944947

Gene position: 1487910-1488461 (Clockwise)

Preceding gene: 119944946

Following gene: 119944949

Centisome position: 32.63

GC content: 40.58

Gene sequence:

>552_bases
ATGTTAAACATCCCAAATTTATTAACGGGTTTTCGACTTTTCTTAATCCCCATTTTTGTATTTTTTTATTTTTCACCCTT
TAACTGGGGTGAGTTAATTGCAGCTTTTCTTTTTTTAACCGCTGGAATAACGGATTATTTAGATGGTTACCTCGCTAGAA
AACTCGATCAGCAGACTGCTTTTGGTGCTTTTTTGGATCCTGTGGCCGATAAAATAATGGTGGCGGTGGCATTAGTGATG
ATCGTGGAACACTACGCTGTTATCTGGATAACCATTCCTGCGATGGTTATGATCTGCCGAGAAATAATCATTTCTGCTCT
TCGAGAGTGGATGGCAGAACTTGGGGAAAGATCCAGCGTTGCTGTTTCATGGATCGGCAAAGTAAAAACAGTTGCTCAGA
TGACTGCACTTTTTTTACTGATTTGGCAGCATTCAATCGTCATGGAGTGGTTAGGTTTCATCGCTTTATATATAGCAACC
GGATTAACACTTTGGTCGATGGTTGTCTATTTGCGCGCGGCATGGCCAGCACTGAGTAAAAATTCACTATAA

Upstream 100 bases:

>100_bases
AAACCATAAAATGCAAAAATAGCTTATAATCAAGCTGGTTATAAATTTGTAAACTTGTATTTCCAAGTGAATTGGGGATC
GATCATCAAAGGACATTTTA

Downstream 100 bases:

>100_bases
TTAGTCTATTAAGGCAGCGCTTCGTTTAAAAAAGAAGCTAACAGTATAAAACTGATAAAAAAATTGTTAAAGTGTATTGA
CTCATTTCTAATAATCATTA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MLNIPNLLTGFRLFLIPIFVFFYFSPFNWGELIAAFLFLTAGITDYLDGYLARKLDQQTAFGAFLDPVADKIMVAVALVM
IVEHYAVIWITIPAMVMICREIIISALREWMAELGERSSVAVSWIGKVKTVAQMTALFLLIWQHSIVMEWLGFIALYIAT
GLTLWSMVVYLRAAWPALSKNSL

Sequences:

>Translated_183_residues
MLNIPNLLTGFRLFLIPIFVFFYFSPFNWGELIAAFLFLTAGITDYLDGYLARKLDQQTAFGAFLDPVADKIMVAVALVM
IVEHYAVIWITIPAMVMICREIIISALREWMAELGERSSVAVSWIGKVKTVAQMTALFLLIWQHSIVMEWLGFIALYIAT
GLTLWSMVVYLRAAWPALSKNSL
>Mature_183_residues
MLNIPNLLTGFRLFLIPIFVFFYFSPFNWGELIAAFLFLTAGITDYLDGYLARKLDQQTAFGAFLDPVADKIMVAVALVM
IVEHYAVIWITIPAMVMICREIIISALREWMAELGERSSVAVSWIGKVKTVAQMTALFLLIWQHSIVMEWLGFIALYIAT
GLTLWSMVVYLRAAWPALSKNSL

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=172, Percent_Identity=59.8837209302326, Blast_Score=210, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20733; Mature: 20733

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNIPNLLTGFRLFLIPIFVFFYFSPFNWGELIAAFLFLTAGITDYLDGYLARKLDQQTA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGAFLDPVADKIMVAVALVMIVEHYAVIWITIPAMVMICREIIISALREWMAELGERSSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AVSWIGKVKTVAQMTALFLLIWQHSIVMEWLGFIALYIATGLTLWSMVVYLRAAWPALSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NSL
CCC
>Mature Secondary Structure
MLNIPNLLTGFRLFLIPIFVFFYFSPFNWGELIAAFLFLTAGITDYLDGYLARKLDQQTA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGAFLDPVADKIMVAVALVMIVEHYAVIWITIPAMVMICREIIISALREWMAELGERSSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AVSWIGKVKTVAQMTALFLLIWQHSIVMEWLGFIALYIATGLTLWSMVVYLRAAWPALSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NSL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]