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The map label for this gene is uvrC [H]

Identifier: 119944946

GI number: 119944946

Start: 1485929

End: 1487758

Strand: Direct

Name: uvrC [H]

Synonym: Ping_1193

Alternate gene names: 119944946

Gene position: 1485929-1487758 (Clockwise)

Preceding gene: 119944945

Following gene: 119944947

Centisome position: 32.59

GC content: 41.09

Gene sequence:

>1830_bases
ATGAGTGATTTTTGCCCGACCGATTTTTTAAAAACGGTCACCTCTGAACCGGGTGTCTACCGCATGTTTAACCAACAAAA
AGTGATTTATGTTGGTAAAGCAAAAAACCTGAAAAAACGCCTCAGCAGTTATTTTAGCCTTACCCAAAAACACCCTAAAA
CATTAGCGCTGGTCAGTCATATTGACAGAATTGAAGTGACGGTCACGCACACTGAAACTGAAGCACTGATCCTCGAACAC
AACTTTATCAAGCGTTACAAGCCTCATTATAATGTGTTGTTACGTGATGATAAGTCTTATCCTTACCTGTTTTTAAGTGA
CCATAAACATCCACAACTGACTTTAGTGCGTACCCAAAATAGTAAACGAAAAGGGACCTATTTTGGCCCCTATCCGAGTG
GTGGGGCGGTGAGAGAAAGTCTGCATTTAATGCAAAAACTGTTTCCAATACGTCAATGTGAAGACAGTTATTACAGCAAT
CGCTCCCGTCCCTGTCTGCAGTATCAATTAAAACGTTGTCTTGCGCCCTGCGTCAATGCGATGCCGGAATCTGAATATCA
GCACCAAGTTGAATTAGCCAGTGCCTTCTTACAAGGTAAAAGTCAAAATGTGATAAATCAGCTGGTTGATGAAATGGAAG
TGGCAAGTCAGACCCTTGAATTTGAGAAAGCAGCGGTGCGACGCGATCAAATCCAATCCTTAAAAAAAGTGCAGGAACAG
CAATGGGTCAGCGGTGATATTGAACAGTTAGATGTTGTCGGTTTCAGTTATGAGCAAGGTTTTGCCAGTATACACCTACT
GTTTGTCCGTCAGGGGCGAATATTAGGTAGCCGTAATTATTTTCCTAAAATCCCCAAAAACTCGAGTAAAGATGAAGTGT
TAAGCGCTTTTTTAAGCCAGTTTTATCTGTCCGGGCAAAATGGACGCGCAATACCAAGGGAAATTTTGCTCAGTGATGAT
TTTGCTGAACGTGCTATTTTTACTGATTTATTTACTGAATATTGTGGCTATAAAACAGCATTAAAAGTAGATGTGCGTGG
TGAGCGTGCGAGGTTTGTCAAACTGGCACAAAAAAATGCCCAAATAGCATTACAGAGCCATCTCAGCCAAAAAAACAACA
TATTAAAGCGTTATCAGCTGCTGGAGGCGAAATTGGACTTAAGTAAACCGATTTTGCGCATGGAATGTTATGATATTTCG
CATATGATGGGGGAAAAAACAGTCGCATCCTGTGTTGTGTTTAATCGTGAGGGGGAAAAAAAATCTGATTACCGTCGTTT
TAATATTACTGGTATTACGCCTGGCGATGACTATGCGGCAATGGGACAAGTGCTAGCGCGACGTTTTAAAGCGCTGCAGG
AGACAGAAAACATTCCTGATATTATTTTTATCGACGGGGGGGTGGGGCAATTAAACCAAGCTGAAAATATTATTAGCTCT
CTTGAAGAAAACTTTAAAGATAAATACCCGTTATTGATAGGTATTGCCAAAGGCGAAGGCCGTAAGCCTGGCTTAGAAAC
ACTTATTTTAGCCGGAACCCACGAAATTATTGAATTGAGCAGTGATTCACCTGCGCTGCATTTAATACAGCAAATTCGTG
ATGAATCGCATCGTTTTGCGATTATGGGGCATCGCCAGCAACGTGATAAAACAAGAAGAACAAGTACATTAGAAAATATC
AGTGGAGTAGGCACTAAACGTCGTCAGGCGTTATTAAACCACTTAGGGGGATTACAGGGTGTTATGTCCGCAAGTATTGA
CGAATTGCAAAAAATTCCCGGCATAAGCGCTTCATTAGCTGAAACAATTTATGAAGCTTTGCATAATTAA

Upstream 100 bases:

>100_bases
TGCTGTAATCTGTTGCAGATGTAATGTAAAAAATAAGGGCGACTGAAAATGCACAATTTAGCCTTGTTAAGTAGTTTACT
GTGCGAGGTTTATTTTTTAT

Downstream 100 bases:

>100_bases
TAAAAATTAAAATGGTAATCCTATTAATTACTCTTTAGGATTTGCATAATGAAACCATAAAATGCAAAAATAGCTTATAA
TCAAGCTGGTTATAAATTTG

Product: excinuclease ABC, C subunit

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MSDFCPTDFLKTVTSEPGVYRMFNQQKVIYVGKAKNLKKRLSSYFSLTQKHPKTLALVSHIDRIEVTVTHTETEALILEH
NFIKRYKPHYNVLLRDDKSYPYLFLSDHKHPQLTLVRTQNSKRKGTYFGPYPSGGAVRESLHLMQKLFPIRQCEDSYYSN
RSRPCLQYQLKRCLAPCVNAMPESEYQHQVELASAFLQGKSQNVINQLVDEMEVASQTLEFEKAAVRRDQIQSLKKVQEQ
QWVSGDIEQLDVVGFSYEQGFASIHLLFVRQGRILGSRNYFPKIPKNSSKDEVLSAFLSQFYLSGQNGRAIPREILLSDD
FAERAIFTDLFTEYCGYKTALKVDVRGERARFVKLAQKNAQIALQSHLSQKNNILKRYQLLEAKLDLSKPILRMECYDIS
HMMGEKTVASCVVFNREGEKKSDYRRFNITGITPGDDYAAMGQVLARRFKALQETENIPDIIFIDGGVGQLNQAENIISS
LEENFKDKYPLLIGIAKGEGRKPGLETLILAGTHEIIELSSDSPALHLIQQIRDESHRFAIMGHRQQRDKTRRTSTLENI
SGVGTKRRQALLNHLGGLQGVMSASIDELQKIPGISASLAETIYEALHN

Sequences:

>Translated_609_residues
MSDFCPTDFLKTVTSEPGVYRMFNQQKVIYVGKAKNLKKRLSSYFSLTQKHPKTLALVSHIDRIEVTVTHTETEALILEH
NFIKRYKPHYNVLLRDDKSYPYLFLSDHKHPQLTLVRTQNSKRKGTYFGPYPSGGAVRESLHLMQKLFPIRQCEDSYYSN
RSRPCLQYQLKRCLAPCVNAMPESEYQHQVELASAFLQGKSQNVINQLVDEMEVASQTLEFEKAAVRRDQIQSLKKVQEQ
QWVSGDIEQLDVVGFSYEQGFASIHLLFVRQGRILGSRNYFPKIPKNSSKDEVLSAFLSQFYLSGQNGRAIPREILLSDD
FAERAIFTDLFTEYCGYKTALKVDVRGERARFVKLAQKNAQIALQSHLSQKNNILKRYQLLEAKLDLSKPILRMECYDIS
HMMGEKTVASCVVFNREGEKKSDYRRFNITGITPGDDYAAMGQVLARRFKALQETENIPDIIFIDGGVGQLNQAENIISS
LEENFKDKYPLLIGIAKGEGRKPGLETLILAGTHEIIELSSDSPALHLIQQIRDESHRFAIMGHRQQRDKTRRTSTLENI
SGVGTKRRQALLNHLGGLQGVMSASIDELQKIPGISASLAETIYEALHN
>Mature_608_residues
SDFCPTDFLKTVTSEPGVYRMFNQQKVIYVGKAKNLKKRLSSYFSLTQKHPKTLALVSHIDRIEVTVTHTETEALILEHN
FIKRYKPHYNVLLRDDKSYPYLFLSDHKHPQLTLVRTQNSKRKGTYFGPYPSGGAVRESLHLMQKLFPIRQCEDSYYSNR
SRPCLQYQLKRCLAPCVNAMPESEYQHQVELASAFLQGKSQNVINQLVDEMEVASQTLEFEKAAVRRDQIQSLKKVQEQQ
WVSGDIEQLDVVGFSYEQGFASIHLLFVRQGRILGSRNYFPKIPKNSSKDEVLSAFLSQFYLSGQNGRAIPREILLSDDF
AERAIFTDLFTEYCGYKTALKVDVRGERARFVKLAQKNAQIALQSHLSQKNNILKRYQLLEAKLDLSKPILRMECYDISH
MMGEKTVASCVVFNREGEKKSDYRRFNITGITPGDDYAAMGQVLARRFKALQETENIPDIIFIDGGVGQLNQAENIISSL
EENFKDKYPLLIGIAKGEGRKPGLETLILAGTHEIIELSSDSPALHLIQQIRDESHRFAIMGHRQQRDKTRRTSTLENIS
GVGTKRRQALLNHLGGLQGVMSASIDELQKIPGISASLAETIYEALHN

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=610, Percent_Identity=55.5737704918033, Blast_Score=689, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF00633 HHH; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 69364; Mature: 69233

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFCPTDFLKTVTSEPGVYRMFNQQKVIYVGKAKNLKKRLSSYFSLTQKHPKTLALVSH
CCCCCCHHHHHHHCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHH
IDRIEVTVTHTETEALILEHNFIKRYKPHYNVLLRDDKSYPYLFLSDHKHPQLTLVRTQN
CCEEEEEEEECCCCEEEEEHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCEEEEEECC
SKRKGTYFGPYPSGGAVRESLHLMQKLFPIRQCEDSYYSNRSRPCLQYQLKRCLAPCVNA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
MPESEYQHQVELASAFLQGKSQNVINQLVDEMEVASQTLEFEKAAVRRDQIQSLKKVQEQ
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QWVSGDIEQLDVVGFSYEQGFASIHLLFVRQGRILGSRNYFPKIPKNSSKDEVLSAFLSQ
HHCCCCCHHHEEECCCHHCCCHHEEEEEEECCCEECCCCCCCCCCCCCCHHHHHHHHHHH
FYLSGQNGRAIPREILLSDDFAERAIFTDLFTEYCGYKTALKVDVRGERARFVKLAQKNA
HHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCH
QIALQSHLSQKNNILKRYQLLEAKLDLSKPILRMECYDISHMMGEKTVASCVVFNREGEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHEEECCCCCC
KSDYRRFNITGITPGDDYAAMGQVLARRFKALQETENIPDIIFIDGGVGQLNQAENIISS
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHH
LEENFKDKYPLLIGIAKGEGRKPGLETLILAGTHEIIELSSDSPALHLIQQIRDESHRFA
HHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHCCCCEEE
IMGHRQQRDKTRRTSTLENISGVGTKRRQALLNHLGGLQGVMSASIDELQKIPGISASLA
EECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHH
ETIYEALHN
HHHHHHHCC
>Mature Secondary Structure 
SDFCPTDFLKTVTSEPGVYRMFNQQKVIYVGKAKNLKKRLSSYFSLTQKHPKTLALVSH
CCCCCHHHHHHHCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHH
IDRIEVTVTHTETEALILEHNFIKRYKPHYNVLLRDDKSYPYLFLSDHKHPQLTLVRTQN
CCEEEEEEEECCCCEEEEEHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCEEEEEECC
SKRKGTYFGPYPSGGAVRESLHLMQKLFPIRQCEDSYYSNRSRPCLQYQLKRCLAPCVNA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
MPESEYQHQVELASAFLQGKSQNVINQLVDEMEVASQTLEFEKAAVRRDQIQSLKKVQEQ
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QWVSGDIEQLDVVGFSYEQGFASIHLLFVRQGRILGSRNYFPKIPKNSSKDEVLSAFLSQ
HHCCCCCHHHEEECCCHHCCCHHEEEEEEECCCEECCCCCCCCCCCCCCHHHHHHHHHHH
FYLSGQNGRAIPREILLSDDFAERAIFTDLFTEYCGYKTALKVDVRGERARFVKLAQKNA
HHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCH
QIALQSHLSQKNNILKRYQLLEAKLDLSKPILRMECYDISHMMGEKTVASCVVFNREGEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHEEECCCCCC
KSDYRRFNITGITPGDDYAAMGQVLARRFKALQETENIPDIIFIDGGVGQLNQAENIISS
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHH
LEENFKDKYPLLIGIAKGEGRKPGLETLILAGTHEIIELSSDSPALHLIQQIRDESHRFA
HHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHCCCCEEE
IMGHRQQRDKTRRTSTLENISGVGTKRRQALLNHLGGLQGVMSASIDELQKIPGISASLA
EECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHH
ETIYEALHN
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA