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The map label for this gene is uvrY [H]

Identifier: 119944945

GI number: 119944945

Start: 1485192

End: 1485836

Strand: Direct

Name: uvrY [H]

Synonym: Ping_1192

Alternate gene names: 119944945

Gene position: 1485192-1485836 (Clockwise)

Preceding gene: 119944940

Following gene: 119944946

Centisome position: 32.57

GC content: 42.02

Gene sequence:

>645_bases
GTGATAAATATCCTGTTGGTTGATGACCATGAATTAGTTCGTACAGGGATTTGCCGTATCATTGATGATGTTCGAGGCAT
GAAAGTTATTGGAGAAGCACAAAGTGGTGAAGAGGCCGTAAAATGGTGCCGAAAAAATCACCCCGATGTTGTGTTAATGG
ATATTAATATGCCAGGGATGGGTGGTTTAGATGCAATGCACAAAATTTTGCGTATCAATGAAGATTTAAAAATCATTATG
CTAACAATGCATACCGAGAATCCTTTCCCCTCAAAAGTAATGCAGGCAGGTGCGTCCGGTTACATAAGTAAATCTGCCGG
CCCCGATGAAGTATTAAACGCGATCCGTTTGGTGCATTCCGGGCAACGTTATTTGGCGCCTGAAATTGCACAGAAAATAG
CACTTTCACAACTGTCTCCGACTGCGGATGATCCATTTAGCGTGCTATCAGAAAGAGAGTTACAAATTATGATGATGATA
ACCAAGGGGCAGCGTGTGGTGGATATATCGGAGCAACTTGGTTTAAGCCCAAAAACAATTAATAGCTACCGCTATCGTTT
GTTTGATAAACTCGATGTAAAGGGTGACGTTGGTTTGACTCATTTGGCGATACGTTATGGCATGCTTGATACAGCTATGC
TGTAA

Upstream 100 bases:

>100_bases
CCAAAAGACTATTATCCAGTTGTTATCTCTTTTTTATAGTCCTTGTTTTATTTTTAGCTTAATGTTTTAGTTGTTGCTTT
GGCATTAACGGAGAAATTTT

Downstream 100 bases:

>100_bases
TCTGTTGCAGATGTAATGTAAAAAATAAGGGCGACTGAAAATGCACAATTTAGCCTTGTTAAGTAGTTTACTGTGCGAGG
TTTATTTTTTATATGAGTGA

Product: transcriptional regulator of LuxR family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MINILLVDDHELVRTGICRIIDDVRGMKVIGEAQSGEEAVKWCRKNHPDVVLMDINMPGMGGLDAMHKILRINEDLKIIM
LTMHTENPFPSKVMQAGASGYISKSAGPDEVLNAIRLVHSGQRYLAPEIAQKIALSQLSPTADDPFSVLSERELQIMMMI
TKGQRVVDISEQLGLSPKTINSYRYRLFDKLDVKGDVGLTHLAIRYGMLDTAML

Sequences:

>Translated_214_residues
MINILLVDDHELVRTGICRIIDDVRGMKVIGEAQSGEEAVKWCRKNHPDVVLMDINMPGMGGLDAMHKILRINEDLKIIM
LTMHTENPFPSKVMQAGASGYISKSAGPDEVLNAIRLVHSGQRYLAPEIAQKIALSQLSPTADDPFSVLSERELQIMMMI
TKGQRVVDISEQLGLSPKTINSYRYRLFDKLDVKGDVGLTHLAIRYGMLDTAML
>Mature_214_residues
MINILLVDDHELVRTGICRIIDDVRGMKVIGEAQSGEEAVKWCRKNHPDVVLMDINMPGMGGLDAMHKILRINEDLKIIM
LTMHTENPFPSKVMQAGASGYISKSAGPDEVLNAIRLVHSGQRYLAPEIAQKIALSQLSPTADDPFSVLSERELQIMMMI
TKGQRVVDISEQLGLSPKTINSYRYRLFDKLDVKGDVGLTHLAIRYGMLDTAML

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=215, Percent_Identity=66.9767441860465, Blast_Score=310, Evalue=5e-86,
Organism=Escherichia coli, GI1790102, Length=200, Percent_Identity=34, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1788521, Length=204, Percent_Identity=31.3725490196078, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1786747, Length=207, Percent_Identity=24.1545893719807, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788712, Length=207, Percent_Identity=26.5700483091787, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787473, Length=183, Percent_Identity=27.8688524590164, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788546, Length=201, Percent_Identity=26.3681592039801, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23830; Mature: 23830

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINILLVDDHELVRTGICRIIDDVRGMKVIGEAQSGEEAVKWCRKNHPDVVLMDINMPGM
CEEEEEECCHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCCCEEEEEECCCCC
GGLDAMHKILRINEDLKIIMLTMHTENPFPSKVMQAGASGYISKSAGPDEVLNAIRLVHS
CCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
GQRYLAPEIAQKIALSQLSPTADDPFSVLSERELQIMMMITKGQRVVDISEQLGLSPKTI
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEEEECCCEEEEEHHHHCCCCCHH
NSYRYRLFDKLDVKGDVGLTHLAIRYGMLDTAML
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MINILLVDDHELVRTGICRIIDDVRGMKVIGEAQSGEEAVKWCRKNHPDVVLMDINMPGM
CEEEEEECCHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCCCEEEEEECCCCC
GGLDAMHKILRINEDLKIIMLTMHTENPFPSKVMQAGASGYISKSAGPDEVLNAIRLVHS
CCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
GQRYLAPEIAQKIALSQLSPTADDPFSVLSERELQIMMMITKGQRVVDISEQLGLSPKTI
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEEEECCCEEEEEHHHHCCCCCHH
NSYRYRLFDKLDVKGDVGLTHLAIRYGMLDTAML
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]