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The map label for this gene is mreD [H]

Identifier: 119944880

GI number: 119944880

Start: 1408690

End: 1409091

Strand: Direct

Name: mreD [H]

Synonym: Ping_1124

Alternate gene names: 119944880

Gene position: 1408690-1409091 (Clockwise)

Preceding gene: 119944879

Following gene: 119944881

Centisome position: 30.9

GC content: 37.31

Gene sequence:

>402_bases
ATGCTGAATGCTTTTCGTCCCGATTGGATGATCCTTATTATTTTTTATTGGGTACTCGCATTACCGCATCGGGTTAGCAT
CGTGCATGCGTTTATTTTAGGGGTAGTATTTGACCTTTTATTAGGCTCTACGTTAGGCATGCATGCCTTATTATTTTCAT
TTTTAGCCTACATAGTCATTACCAATTACCAACTTTTTCGTTATTTCACTCTGGTACAAACAACCCTCTTAGTCGGTTTG
TATTCTTTACTGTCGAAACTGGCGTTATATTTGATGGCATCAAGCTTACAAGATATTATTTTACATCAATCTTATTTCTG
GTCAGTCTTTACCTCGATGCTGGTTTGGCCCTGGTTTTTTCTTTTTTTGCGTTTTATTCGTCGCCGTTTTAAGGTCGTAT
AA

Upstream 100 bases:

>100_bases
GAACCGCTGGAATCGAAAAATGTCATTGTTCAGTAACTATATGGCCATTTACTTTACTTATTTTGCAGGTTTAGTCTGTG
CTATTGTTCCTCTTCCTATC

Downstream 100 bases:

>100_bases
GCATGAACGTTTCTATCTATCTTGCATCGAGTTCACCTCGTCGTAGTGAACTTCTAAATCAAATTGGAGTCTTATTTGAT
CGAGTGAAAGCTGCCATTGA

Product: rod shape-determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MLNAFRPDWMILIIFYWVLALPHRVSIVHAFILGVVFDLLLGSTLGMHALLFSFLAYIVITNYQLFRYFTLVQTTLLVGL
YSLLSKLALYLMASSLQDIILHQSYFWSVFTSMLVWPWFFLFLRFIRRRFKVV

Sequences:

>Translated_133_residues
MLNAFRPDWMILIIFYWVLALPHRVSIVHAFILGVVFDLLLGSTLGMHALLFSFLAYIVITNYQLFRYFTLVQTTLLVGL
YSLLSKLALYLMASSLQDIILHQSYFWSVFTSMLVWPWFFLFLRFIRRRFKVV
>Mature_133_residues
MLNAFRPDWMILIIFYWVLALPHRVSIVHAFILGVVFDLLLGSTLGMHALLFSFLAYIVITNYQLFRYFTLVQTTLLVGL
YSLLSKLALYLMASSLQDIILHQSYFWSVFTSMLVWPWFFLFLRFIRRRFKVV

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family [H]

Homologues:

Organism=Escherichia coli, GI1789647, Length=128, Percent_Identity=41.40625, Blast_Score=101, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007227 [H]

Pfam domain/function: PF04093 MreD [H]

EC number: NA

Molecular weight: Translated: 15810; Mature: 15810

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNAFRPDWMILIIFYWVLALPHRVSIVHAFILGVVFDLLLGSTLGMHALLFSFLAYIVI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
TNYQLFRYFTLVQTTLLVGLYSLLSKLALYLMASSLQDIILHQSYFWSVFTSMLVWPWFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFLRFIRRRFKVV
HHHHHHHHHHCCC
>Mature Secondary Structure
MLNAFRPDWMILIIFYWVLALPHRVSIVHAFILGVVFDLLLGSTLGMHALLFSFLAYIVI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
TNYQLFRYFTLVQTTLLVGLYSLLSKLALYLMASSLQDIILHQSYFWSVFTSMLVWPWFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFLRFIRRRFKVV
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]