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The map label for this gene is aroC

Identifier: 119944776

GI number: 119944776

Start: 1280230

End: 1281318

Strand: Direct

Name: aroC

Synonym: Ping_1018

Alternate gene names: 119944776

Gene position: 1280230-1281318 (Clockwise)

Preceding gene: 119944775

Following gene: 119944778

Centisome position: 28.08

GC content: 45.27

Gene sequence:

>1089_bases
ATGGCGGGCAGCAGTATTGGTCAACTCTTTAAAGTCACCACCTTTGGCGAAAGTCACGGTGCAGCAATAGGTTGTATTGT
GGATGGTATTCCACCAAATTTAGAAATTTGTGAAGCTGATCTGCAGCATGATTTAGACCGGCGTCGCCCCGGGCAGTCAC
GTTATACAACAATGCGCCAGGAAAAGGATCAAGTTAAGATTCTTTCCGGCGTTTTTGAAGGTAAAACAACCGGCAGCAGT
ATCGGTTTAATGATTGAAAATACTGATCAGCGTTCCAAGGATTATTCTGAAATTAAGGATTTGTTCCGTCCGGGACATGC
CGATTACACTTACCATCAAAAATTTGGACACCGCGATTATCGGGGTGGGGGTCGTTCTTCTGCGCGCGAAACAGCGATGC
GTGTTGCCGCCGGTGCGATTGCTAAAAAATATTTAAATGAACAGTTTGGTATTGTTATTCGTGGTTATTTAAGTCAGTTA
GGTGATATTAAAGCCGATTCAATTGACTTGGATGAAGTTGAAAACAATCCCTTTTTCTTCCCTGATCTGTCTAAAATCAC
GCAGCTTGAAGATTATATGAAAGCCCTGATTAAAGAGGGTAACTCAGTAGGGGCGAAAGTCACCGTAGTTGCATCGAGTG
TGCCCGTTGGTCTGGGCGAGCCGGTCTTTGATCGTTTAGATGCAGAGCTTGCGCATTCATTAATGAGTATTAATGCGGTT
AAAGGGGTTGAAATTGGTGACGGTTTTGCAGCTGTTAGTCAAAAGGGAACTGAGCATCGTGATGAAATGACCCCGGGCGG
TTTTTTATCAAACCATGCGGGCGGCATATTAGGCGGAATTTCAACGGGTCAGGACATTATCGCCCATATCGCTCTAAAAC
CCACCTCAAGTTTAACTATTCCCGGTCGCACTATTACCACCAATGGCGAAGCGACTACCATGATAACCAAAGGGCGTCAC
GATCCCTGTGTCGGTATTCGCGCAGTGCCCATTGCAGAAGCACAAATGGCCATTACCTTGCTTGACCATCTATTGCGTCA
TCGCGCACAGAACTTACATGTAACGACCAATACACCCTTTATTAAATAA

Upstream 100 bases:

>100_bases
AAAAATATTAAAATTTAATTTTTTTAAGCAATATTTCAGATTAACTGCTGCAAATTTTAATGGTCTGCAGTTTTGTACAA
TTTAAAAACGGGAAATAATT

Downstream 100 bases:

>100_bases
GTTGGCTGACAAGCCACTAATTGAATGATGGGTATTATATAAACAAACCACTTGTGGATGCCTCTTCAAGTGGTTTTTTT
ATTAGTTGATATTTTCCCGG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MAGSSIGQLFKVTTFGESHGAAIGCIVDGIPPNLEICEADLQHDLDRRRPGQSRYTTMRQEKDQVKILSGVFEGKTTGSS
IGLMIENTDQRSKDYSEIKDLFRPGHADYTYHQKFGHRDYRGGGRSSARETAMRVAAGAIAKKYLNEQFGIVIRGYLSQL
GDIKADSIDLDEVENNPFFFPDLSKITQLEDYMKALIKEGNSVGAKVTVVASSVPVGLGEPVFDRLDAELAHSLMSINAV
KGVEIGDGFAAVSQKGTEHRDEMTPGGFLSNHAGGILGGISTGQDIIAHIALKPTSSLTIPGRTITTNGEATTMITKGRH
DPCVGIRAVPIAEAQMAITLLDHLLRHRAQNLHVTTNTPFIK

Sequences:

>Translated_362_residues
MAGSSIGQLFKVTTFGESHGAAIGCIVDGIPPNLEICEADLQHDLDRRRPGQSRYTTMRQEKDQVKILSGVFEGKTTGSS
IGLMIENTDQRSKDYSEIKDLFRPGHADYTYHQKFGHRDYRGGGRSSARETAMRVAAGAIAKKYLNEQFGIVIRGYLSQL
GDIKADSIDLDEVENNPFFFPDLSKITQLEDYMKALIKEGNSVGAKVTVVASSVPVGLGEPVFDRLDAELAHSLMSINAV
KGVEIGDGFAAVSQKGTEHRDEMTPGGFLSNHAGGILGGISTGQDIIAHIALKPTSSLTIPGRTITTNGEATTMITKGRH
DPCVGIRAVPIAEAQMAITLLDHLLRHRAQNLHVTTNTPFIK
>Mature_361_residues
AGSSIGQLFKVTTFGESHGAAIGCIVDGIPPNLEICEADLQHDLDRRRPGQSRYTTMRQEKDQVKILSGVFEGKTTGSSI
GLMIENTDQRSKDYSEIKDLFRPGHADYTYHQKFGHRDYRGGGRSSARETAMRVAAGAIAKKYLNEQFGIVIRGYLSQLG
DIKADSIDLDEVENNPFFFPDLSKITQLEDYMKALIKEGNSVGAKVTVVASSVPVGLGEPVFDRLDAELAHSLMSINAVK
GVEIGDGFAAVSQKGTEHRDEMTPGGFLSNHAGGILGGISTGQDIIAHIALKPTSSLTIPGRTITTNGEATTMITKGRHD
PCVGIRAVPIAEAQMAITLLDHLLRHRAQNLHVTTNTPFIK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=359, Percent_Identity=75.4874651810585, Blast_Score=541, Evalue=1e-155,
Organism=Saccharomyces cerevisiae, GI6321290, Length=369, Percent_Identity=43.0894308943089, Blast_Score=301, Evalue=1e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_PSYIN (A1STP2)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942456.1
- ProteinModelPortal:   A1STP2
- SMR:   A1STP2
- STRING:   A1STP2
- GeneID:   4624161
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1018
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   A1STP2
- ProtClustDB:   PRK05382
- BioCyc:   PING357804:PING_1018-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39145; Mature: 39014

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSSIGQLFKVTTFGESHGAAIGCIVDGIPPNLEICEADLQHDLDRRRPGQSRYTTMRQ
CCCCCHHHEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
EKDQVKILSGVFEGKTTGSSIGLMIENTDQRSKDYSEIKDLFRPGHADYTYHQKFGHRDY
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLNEQFGIVIRGYLSQLGDIKADSIDLDEVENNPFFF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHCCCCCEEC
PDLSKITQLEDYMKALIKEGNSVGAKVTVVASSVPVGLGEPVFDRLDAELAHSLMSINAV
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFAAVSQKGTEHRDEMTPGGFLSNHAGGILGGISTGQDIIAHIALKPTSSLTI
CCCEECCCHHHHHCCCCCHHHCCCCCCCCCCCCCCEEECCCCCHHHHEEEEECCCCCEEE
PGRTITTNGEATTMITKGRHDPCVGIRAVPIAEAQMAITLLDHLLRHRAQNLHVTTNTPF
CCEEEECCCCEEEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCEEEECCCCC
IK
CC
>Mature Secondary Structure 
AGSSIGQLFKVTTFGESHGAAIGCIVDGIPPNLEICEADLQHDLDRRRPGQSRYTTMRQ
CCCCHHHEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
EKDQVKILSGVFEGKTTGSSIGLMIENTDQRSKDYSEIKDLFRPGHADYTYHQKFGHRDY
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLNEQFGIVIRGYLSQLGDIKADSIDLDEVENNPFFF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCHHHCCCCCEEC
PDLSKITQLEDYMKALIKEGNSVGAKVTVVASSVPVGLGEPVFDRLDAELAHSLMSINAV
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFAAVSQKGTEHRDEMTPGGFLSNHAGGILGGISTGQDIIAHIALKPTSSLTI
CCCEECCCHHHHHCCCCCHHHCCCCCCCCCCCCCCEEECCCCCHHHHEEEEECCCCCEEE
PGRTITTNGEATTMITKGRHDPCVGIRAVPIAEAQMAITLLDHLLRHRAQNLHVTTNTPF
CCEEEECCCCEEEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCEEEECCCCC
IK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA