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The map label for this gene is nhaA [H]

Identifier: 119944686

GI number: 119944686

Start: 1159603

End: 1160568

Strand: Direct

Name: nhaA [H]

Synonym: Ping_0925

Alternate gene names: 119944686

Gene position: 1159603-1160568 (Clockwise)

Preceding gene: 119944685

Following gene: 119944688

Centisome position: 25.43

GC content: 39.03

Gene sequence:

>966_bases
ATGGAAAATAAAACACAGACTGAAGACCGCTGGATAAAAGCTTTTATCAAGGAAAATTTCGCAGAGCAGAAAAGAACGCG
GCGTTGGGGAATTTTCTTCAAATCATTAACTTTTTTGTATCTGTTTGGCGCCATCTTTTTCTTTTTTAATACTCAAACGA
ATCTCTTAAGTGATCAACAAAAAGAGCCGCATACCGCTATGGTGCAAATAAAAGGTGTTATTGCCGCAGATAAAGAAGCG
AATGCAAATACTATTGTCACCGGTTTACGTGCTGCATTTAAAAATGAGTTCAGTCAGGCGGTTATGTTAGTGATCAATAG
CCCTGGTGGTAGTCCCGTTCAGGCAGGTTATGTATTTGATGAAATACAACGTCTGCGTCTTTTATACCCGGATAAAAAAT
TGTATGCCGTTATTGCTGAATTAGGTGCCTCGGGTGGTTATTATATTGCAGCTGCAGCTGACCAGATATATGCGGATAAA
GCGAGTCTTGTCGGGTCGATTGGGGTGACTGCATCCAGTTTTGGTTTTGTTGATCTGATGAATAAAGTTGGGGTTGAACG
TCGCCACTATACTTCTGGCAAACATAAGACATTTTTAGATCCGTTTTCACCCAGCAAAGAAGCCGAACGAGATTTTTGGC
AGGAAGTGTTAGATGTGACTCACCGGCAGTTTATTAATGTGGTTAAAACTGGACGAGGCGATCGTATTAATTCAGATAAA
AATTCAACGGATCTGTTTTCTGGTTTGATTTGGAATGGTGAACAAGCTTTAGCGCTAGGTCTAATTGACGGTTTAGGAAG
TCCGGGATTTGTTGCCAGAGAGATTGTTAGAGCAGAAAATATTGTGAATTATTCTGTACAACCTTCTACTATTGAAAAAT
TAACTAAACGTTTAGGTATTTCAATAGGTAATGGTTTTGCTAATCAATTGGTTAGTGACAACAAGGGAATAAATTTAGGT
CTCTAA

Upstream 100 bases:

>100_bases
TCATTATGTCTGGACCTGCTGATCTCAGTATTTTAGGGGGGGCTTGGCAGTGACCTTGCAATCATTTAATCATCCTTAAC
CTACAAACTGGGTATATAAA

Downstream 100 bases:

>100_bases
AAAAAACATAACCTCAATTTTTTATGTTGGGTTATCGACCCAGATGACTTGTAGAGGCTGATTCTGGCCTCTACAAGTCA
TCTGGGTGCATTATTTTGTT

Product: peptidase S49

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MENKTQTEDRWIKAFIKENFAEQKRTRRWGIFFKSLTFLYLFGAIFFFFNTQTNLLSDQQKEPHTAMVQIKGVIAADKEA
NANTIVTGLRAAFKNEFSQAVMLVINSPGGSPVQAGYVFDEIQRLRLLYPDKKLYAVIAELGASGGYYIAAAADQIYADK
ASLVGSIGVTASSFGFVDLMNKVGVERRHYTSGKHKTFLDPFSPSKEAERDFWQEVLDVTHRQFINVVKTGRGDRINSDK
NSTDLFSGLIWNGEQALALGLIDGLGSPGFVAREIVRAENIVNYSVQPSTIEKLTKRLGISIGNGFANQLVSDNKGINLG
L

Sequences:

>Translated_321_residues
MENKTQTEDRWIKAFIKENFAEQKRTRRWGIFFKSLTFLYLFGAIFFFFNTQTNLLSDQQKEPHTAMVQIKGVIAADKEA
NANTIVTGLRAAFKNEFSQAVMLVINSPGGSPVQAGYVFDEIQRLRLLYPDKKLYAVIAELGASGGYYIAAAADQIYADK
ASLVGSIGVTASSFGFVDLMNKVGVERRHYTSGKHKTFLDPFSPSKEAERDFWQEVLDVTHRQFINVVKTGRGDRINSDK
NSTDLFSGLIWNGEQALALGLIDGLGSPGFVAREIVRAENIVNYSVQPSTIEKLTKRLGISIGNGFANQLVSDNKGINLG
L
>Mature_321_residues
MENKTQTEDRWIKAFIKENFAEQKRTRRWGIFFKSLTFLYLFGAIFFFFNTQTNLLSDQQKEPHTAMVQIKGVIAADKEA
NANTIVTGLRAAFKNEFSQAVMLVINSPGGSPVQAGYVFDEIQRLRLLYPDKKLYAVIAELGASGGYYIAAAADQIYADK
ASLVGSIGVTASSFGFVDLMNKVGVERRHYTSGKHKTFLDPFSPSKEAERDFWQEVLDVTHRQFINVVKTGRGDRINSDK
NSTDLFSGLIWNGEQALALGLIDGLGSPGFVAREIVRAENIVNYSVQPSTIEKLTKRLGISIGNGFANQLVSDNKGINLG
L

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=238, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR002142 [H]

Pfam domain/function: PF06965 Na_H_antiport_1; PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 35611; Mature: 35611

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKTQTEDRWIKAFIKENFAEQKRTRRWGIFFKSLTFLYLFGAIFFFFNTQTNLLSDQQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
KEPHTAMVQIKGVIAADKEANANTIVTGLRAAFKNEFSQAVMLVINSPGGSPVQAGYVFD
CCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEECHHHHH
EIQRLRLLYPDKKLYAVIAELGASGGYYIAAAADQIYADKASLVGSIGVTASSFGFVDLM
HHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHH
NKVGVERRHYTSGKHKTFLDPFSPSKEAERDFWQEVLDVTHRQFINVVKTGRGDRINSDK
HHHCCCHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NSTDLFSGLIWNGEQALALGLIDGLGSPGFVAREIVRAENIVNYSVQPSTIEKLTKRLGI
CCHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
SIGNGFANQLVSDNKGINLGL
CCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MENKTQTEDRWIKAFIKENFAEQKRTRRWGIFFKSLTFLYLFGAIFFFFNTQTNLLSDQQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
KEPHTAMVQIKGVIAADKEANANTIVTGLRAAFKNEFSQAVMLVINSPGGSPVQAGYVFD
CCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEECHHHHH
EIQRLRLLYPDKKLYAVIAELGASGGYYIAAAADQIYADKASLVGSIGVTASSFGFVDLM
HHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHH
NKVGVERRHYTSGKHKTFLDPFSPSKEAERDFWQEVLDVTHRQFINVVKTGRGDRINSDK
HHHCCCHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NSTDLFSGLIWNGEQALALGLIDGLGSPGFVAREIVRAENIVNYSVQPSTIEKLTKRLGI
CCHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
SIGNGFANQLVSDNKGINLGL
CCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA