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The map label for this gene is arcB [H]

Identifier: 119944685

GI number: 119944685

Start: 1157217

End: 1159478

Strand: Direct

Name: arcB [H]

Synonym: Ping_0924

Alternate gene names: 119944685

Gene position: 1157217-1159478 (Clockwise)

Preceding gene: 119944683

Following gene: 119944686

Centisome position: 25.38

GC content: 38.95

Gene sequence:

>2262_bases
TTGAGCCTATTTAACCTTAAAACTTGGGTGCATTATTATGTTGCATTACTGAAACGCCTAGGAGTCTTGCGTTTTAGTTT
GTTACTTGCCATTGCAATTATAAGTGCTGATTCCGCGTTACAAGTCTTCCTTACAATTTATTTTGATGAGCCCTTAAGCA
TTGCCGGTGCTTCCCGTTCAATTTTAATCGGGCTTTTAATAACACCCTGGGCCGTGTATTTTTTGACCGTTGTGGTTGGA
GATTTGGAGGAAGCCAGAATGCATTTAGATAATACTGTTGCTAGTCTCCGCGAGGTGCGCCAAAAAGAGCGGATTAAAAC
CCACGAGTTAGAAAAAGAAATTATTGAGCGTAAAGCAAGCCAGCAGAAATTGGTCGAAGCTGCCAGTTTATTAAAATCAT
TTCTGAATACCTCTCCTGATTTGGTCTTTCACCGAGATTTAAAGAGTCGCTTTGTCAGCTGTAATAAAGCGATGGAGATG
CTCACCGGTAAAACAGAAAAACAGCTTATTAGTTTAACACCCTTTGATATATTTCCCGAGGATTATGCGCACCAAGCTGT
CACCCGTGATCAAAATGTGAAGAAACAAAAAAAAGAACAAATTCATGAGCATTGGTTACATTTTCCAAACGGAAAAAAAG
CTTATTTTGAAGTCAGAACATTGCCACTTTTTAATAGTGAGGCTGTGTGTATTGGTATTATTGGTTTTGGTCGGGATATA
ACCGAGCGTAAAAAACATCAAGAATCTATCGACAAAAATATTCGCGAAAAAACTGATTTTATTTCTTCAATTAGTCACGA
GCTACGCACTCCTTTAAACGGCATAGTGGGTTTAAGCCGCATGTTATTAGATGAGCAGTTGACCAGTGAACAGATGAAAC
ATCTTAAAACCATTCATATCAGCGCCATTAGTTTGGGCAATATCTTCAGTGATATTATTAACTTGGATAAATTAGATCGT
AACCGTCTGAAGTTGGCAACCAATAAGATCAATATGTTGGATTTTATTAGTGACTTAAAAAGTTTATCTTTTATTCAGAC
TGAGCAGAAGGGACTAGTATTAAATTTTGAGCAACGCGGTCATTTTCCAGACATTATTGAAACAGATGATACCCGTTTAA
GGCAGGTTTTATGGAACCTGATAAGCAATGCGGTGAAGTTCACCCAAAAAGGAACGATAACGATCCGCTGTGTCTGTCAT
CAGCTCAACCAGAATCAGGTTGAGCTGTGTTTTGAGGTTGAAGATTCAGGCATTGGTATTCCCGAGGATCAGCTCGATAA
AATTTTTGCAATGTATTATCAGGTTGAAGGTAATACATTTGCGACTGGTACGGGGATAGGGCTTGCTGTCACCTCTAAAA
TTGCGCAAGCAATGGGAGGCGTTATAAGCGTAAAGAGTAAACTTGGCGAAGGCAGTATGTTTAAGCTGACCTTAACGGTG
AATTGCCCGGCAAAAGAACATCAAGAACAACAAATAAAGGATAATCTGCCCAAGCTTTCTATTTTACTTGTGGAAGATAT
CGAACTGAATATTTTGGTCGCAACATCGTTATTAGAAAAGCTTGGCCATAAAGTTGATAGCGCTGTCAATGGTGCGCAGG
CACTGAATAAGGTTGCAGATAATGCCTATCAATTGATCCTGATGGATATTCAACTACCCGATATGAATGGTTATCAGGTC
ACTCAAAAATTACGTGAAATACACGGACATAAGCTGCCTCCTATTGTCGCCCTGACCGCTAACGTATTTGCCGACAGTAA
GGGGTTTATAGAGCAGGGAATGGATGGCGCATTGGGCAAACCGCTTAGTGTTAACCCTTTTAATTCGATGATTAAAAAAT
TATTTGTCCCTTCTAATAAGCATCAGAAAATGGACTCGGTATTAAAAATGCAGCAAAGGATGCAACAGACTAATACCTTG
TTTAATCAAGAAATGCTTTTAGAATTAATGGCGTTTTTACCCACGTCAGTAATTTTAGAGAATGTCGCTTTATTTGAAAA
ATTACTGCCGGAATACCTTGAAATTTTGGATTCTAATATGATTGCCAAGGATCAAAAAGGTATTGTAAATGAAGCTCATA
AAATCAAAGGCGCTGCAGGCTCTGTTGGCTTAAAGCGAATACAGGGCATTGCCCAACAACTCCAATCACCGGATCTTCCT
GCCTGGTGGGATAATATTGATGATTGGGTAGCGTTAATTAAATCTGAATCTCCAAAGGATATAACGGCTTTGAAAAAATG
GATTGTCGCTAATGGTAAATAA

Upstream 100 bases:

>100_bases
TATAGAATGGAGAATCAATGGACCTCTCGATGGAAGCTGAACCTTTATCAATTTCTGGAACCAAGATGAGGTGTTATCTA
TCTATTTAACTGGAGTTAAT

Downstream 100 bases:

>100_bases
AACCTTTTAAATGTGGTTAGAATGTCATTATGTCTGGACCTGCTGATCTCAGTATTTTAGGGGGGGCTTGGCAGTGACCT
TGCAATCATTTAATCATCCT

Product: aerobic respiration control sensor protein ArcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 753; Mature: 752

Protein sequence:

>753_residues
MSLFNLKTWVHYYVALLKRLGVLRFSLLLAIAIISADSALQVFLTIYFDEPLSIAGASRSILIGLLITPWAVYFLTVVVG
DLEEARMHLDNTVASLREVRQKERIKTHELEKEIIERKASQQKLVEAASLLKSFLNTSPDLVFHRDLKSRFVSCNKAMEM
LTGKTEKQLISLTPFDIFPEDYAHQAVTRDQNVKKQKKEQIHEHWLHFPNGKKAYFEVRTLPLFNSEAVCIGIIGFGRDI
TERKKHQESIDKNIREKTDFISSISHELRTPLNGIVGLSRMLLDEQLTSEQMKHLKTIHISAISLGNIFSDIINLDKLDR
NRLKLATNKINMLDFISDLKSLSFIQTEQKGLVLNFEQRGHFPDIIETDDTRLRQVLWNLISNAVKFTQKGTITIRCVCH
QLNQNQVELCFEVEDSGIGIPEDQLDKIFAMYYQVEGNTFATGTGIGLAVTSKIAQAMGGVISVKSKLGEGSMFKLTLTV
NCPAKEHQEQQIKDNLPKLSILLVEDIELNILVATSLLEKLGHKVDSAVNGAQALNKVADNAYQLILMDIQLPDMNGYQV
TQKLREIHGHKLPPIVALTANVFADSKGFIEQGMDGALGKPLSVNPFNSMIKKLFVPSNKHQKMDSVLKMQQRMQQTNTL
FNQEMLLELMAFLPTSVILENVALFEKLLPEYLEILDSNMIAKDQKGIVNEAHKIKGAAGSVGLKRIQGIAQQLQSPDLP
AWWDNIDDWVALIKSESPKDITALKKWIVANGK

Sequences:

>Translated_753_residues
MSLFNLKTWVHYYVALLKRLGVLRFSLLLAIAIISADSALQVFLTIYFDEPLSIAGASRSILIGLLITPWAVYFLTVVVG
DLEEARMHLDNTVASLREVRQKERIKTHELEKEIIERKASQQKLVEAASLLKSFLNTSPDLVFHRDLKSRFVSCNKAMEM
LTGKTEKQLISLTPFDIFPEDYAHQAVTRDQNVKKQKKEQIHEHWLHFPNGKKAYFEVRTLPLFNSEAVCIGIIGFGRDI
TERKKHQESIDKNIREKTDFISSISHELRTPLNGIVGLSRMLLDEQLTSEQMKHLKTIHISAISLGNIFSDIINLDKLDR
NRLKLATNKINMLDFISDLKSLSFIQTEQKGLVLNFEQRGHFPDIIETDDTRLRQVLWNLISNAVKFTQKGTITIRCVCH
QLNQNQVELCFEVEDSGIGIPEDQLDKIFAMYYQVEGNTFATGTGIGLAVTSKIAQAMGGVISVKSKLGEGSMFKLTLTV
NCPAKEHQEQQIKDNLPKLSILLVEDIELNILVATSLLEKLGHKVDSAVNGAQALNKVADNAYQLILMDIQLPDMNGYQV
TQKLREIHGHKLPPIVALTANVFADSKGFIEQGMDGALGKPLSVNPFNSMIKKLFVPSNKHQKMDSVLKMQQRMQQTNTL
FNQEMLLELMAFLPTSVILENVALFEKLLPEYLEILDSNMIAKDQKGIVNEAHKIKGAAGSVGLKRIQGIAQQLQSPDLP
AWWDNIDDWVALIKSESPKDITALKKWIVANGK
>Mature_752_residues
SLFNLKTWVHYYVALLKRLGVLRFSLLLAIAIISADSALQVFLTIYFDEPLSIAGASRSILIGLLITPWAVYFLTVVVGD
LEEARMHLDNTVASLREVRQKERIKTHELEKEIIERKASQQKLVEAASLLKSFLNTSPDLVFHRDLKSRFVSCNKAMEML
TGKTEKQLISLTPFDIFPEDYAHQAVTRDQNVKKQKKEQIHEHWLHFPNGKKAYFEVRTLPLFNSEAVCIGIIGFGRDIT
ERKKHQESIDKNIREKTDFISSISHELRTPLNGIVGLSRMLLDEQLTSEQMKHLKTIHISAISLGNIFSDIINLDKLDRN
RLKLATNKINMLDFISDLKSLSFIQTEQKGLVLNFEQRGHFPDIIETDDTRLRQVLWNLISNAVKFTQKGTITIRCVCHQ
LNQNQVELCFEVEDSGIGIPEDQLDKIFAMYYQVEGNTFATGTGIGLAVTSKIAQAMGGVISVKSKLGEGSMFKLTLTVN
CPAKEHQEQQIKDNLPKLSILLVEDIELNILVATSLLEKLGHKVDSAVNGAQALNKVADNAYQLILMDIQLPDMNGYQVT
QKLREIHGHKLPPIVALTANVFADSKGFIEQGMDGALGKPLSVNPFNSMIKKLFVPSNKHQKMDSVLKMQQRMQQTNTLF
NQEMLLELMAFLPTSVILENVALFEKLLPEYLEILDSNMIAKDQKGIVNEAHKIKGAAGSVGLKRIQGIAQQLQSPDLPA
WWDNIDDWVALIKSESPKDITALKKWIVANGK

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=782, Percent_Identity=45.9079283887468, Blast_Score=687, Evalue=0.0,
Organism=Escherichia coli, GI1788713, Length=639, Percent_Identity=26.4475743348983, Blast_Score=179, Evalue=5e-46,
Organism=Escherichia coli, GI87081816, Length=520, Percent_Identity=27.3076923076923, Blast_Score=154, Evalue=3e-38,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=35.4700854700855, Blast_Score=150, Evalue=4e-37,
Organism=Escherichia coli, GI145693157, Length=304, Percent_Identity=29.9342105263158, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=31.8777292576419, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788393, Length=251, Percent_Identity=27.4900398406374, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1788549, Length=372, Percent_Identity=25.8064516129032, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1786783, Length=235, Percent_Identity=26.3829787234043, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI1786600, Length=282, Percent_Identity=25.531914893617, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=27.3469387755102, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1790861, Length=221, Percent_Identity=22.6244343891403, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84868; Mature: 84737

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFNLKTWVHYYVALLKRLGVLRFSLLLAIAIISADSALQVFLTIYFDEPLSIAGASRS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEECCCCCCCCCCHH
ILIGLLITPWAVYFLTVVVGDLEEARMHLDNTVASLREVRQKERIKTHELEKEIIERKAS
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQKLVEAASLLKSFLNTSPDLVFHRDLKSRFVSCNKAMEMLTGKTEKQLISLTPFDIFPE
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCH
DYAHQAVTRDQNVKKQKKEQIHEHWLHFPNGKKAYFEVRTLPLFNSEAVCIGIIGFGRDI
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCEEEEEEECCCCH
TERKKHQESIDKNIREKTDFISSISHELRTPLNGIVGLSRMLLDEQLTSEQMKHLKTIHI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAISLGNIFSDIINLDKLDRNRLKLATNKINMLDFISDLKSLSFIQTEQKGLVLNFEQRG
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCC
HFPDIIETDDTRLRQVLWNLISNAVKFTQKGTITIRCVCHQLNQNQVELCFEVEDSGIGI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCCCEEEEEEECCCCCCC
PEDQLDKIFAMYYQVEGNTFATGTGIGLAVTSKIAQAMGGVISVKSKLGEGSMFKLTLTV
CHHHHHHHHHHHEEECCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEEEE
NCPAKEHQEQQIKDNLPKLSILLVEDIELNILVATSLLEKLGHKVDSAVNGAQALNKVAD
ECCHHHHHHHHHHHCCCCEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NAYQLILMDIQLPDMNGYQVTQKLREIHGHKLPPIVALTANVFADSKGFIEQGMDGALGK
CCEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCHHEEEHHHHCCCCHHHHCCCCCCCCC
PLSVNPFNSMIKKLFVPSNKHQKMDSVLKMQQRMQQTNTLFNQEMLLELMAFLPTSVILE
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
NVALFEKLLPEYLEILDSNMIAKDQKGIVNEAHKIKGAAGSVGLKRIQGIAQQLQSPDLP
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCC
AWWDNIDDWVALIKSESPKDITALKKWIVANGK
HHHCCHHHHHHHHHCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLFNLKTWVHYYVALLKRLGVLRFSLLLAIAIISADSALQVFLTIYFDEPLSIAGASRS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEECCCCCCCCCCHH
ILIGLLITPWAVYFLTVVVGDLEEARMHLDNTVASLREVRQKERIKTHELEKEIIERKAS
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQKLVEAASLLKSFLNTSPDLVFHRDLKSRFVSCNKAMEMLTGKTEKQLISLTPFDIFPE
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCH
DYAHQAVTRDQNVKKQKKEQIHEHWLHFPNGKKAYFEVRTLPLFNSEAVCIGIIGFGRDI
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCEEEEEEECCCCH
TERKKHQESIDKNIREKTDFISSISHELRTPLNGIVGLSRMLLDEQLTSEQMKHLKTIHI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAISLGNIFSDIINLDKLDRNRLKLATNKINMLDFISDLKSLSFIQTEQKGLVLNFEQRG
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCC
HFPDIIETDDTRLRQVLWNLISNAVKFTQKGTITIRCVCHQLNQNQVELCFEVEDSGIGI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCCCEEEEEEECCCCCCC
PEDQLDKIFAMYYQVEGNTFATGTGIGLAVTSKIAQAMGGVISVKSKLGEGSMFKLTLTV
CHHHHHHHHHHHEEECCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEEEE
NCPAKEHQEQQIKDNLPKLSILLVEDIELNILVATSLLEKLGHKVDSAVNGAQALNKVAD
ECCHHHHHHHHHHHCCCCEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NAYQLILMDIQLPDMNGYQVTQKLREIHGHKLPPIVALTANVFADSKGFIEQGMDGALGK
CCEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCHHEEEHHHHCCCCHHHHCCCCCCCCC
PLSVNPFNSMIKKLFVPSNKHQKMDSVLKMQQRMQQTNTLFNQEMLLELMAFLPTSVILE
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
NVALFEKLLPEYLEILDSNMIAKDQKGIVNEAHKIKGAAGSVGLKRIQGIAQQLQSPDLP
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCC
AWWDNIDDWVALIKSESPKDITALKKWIVANGK
HHHCCHHHHHHHHHCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]