Click here to switch to the map view.

The map label for this gene is kdsB

Identifier: 119944664

GI number: 119944664

Start: 1132631

End: 1133398

Strand: Direct

Name: kdsB

Synonym: Ping_0903

Alternate gene names: 119944664

Gene position: 1132631-1133398 (Clockwise)

Preceding gene: 119944663

Following gene: 119944665

Centisome position: 24.84

GC content: 43.62

Gene sequence:

>768_bases
ATGTCATTTATTGTCGTGATACCCGCGCGTTATCATTCAACGCGTTTACCGGCTAAACCGCTGCTTGATATTTTAGGGCA
AACCATGATTGAGCGGGTGACTAACCAAGCTTTAAAAAGTGGCGCCAAACAAGTTATCGTGGCGACCGATGATCAGCGCA
TTGTTGATGCTTTAAAGCATCTTAACGAGATTGATGTGTGCATGACATCCAAGGATCATCAGTCCGGCACGGATCGTTTA
GCTGAGGTTTGCCAGCAATTTAAATTGGCCGATGATGAGATAATAGTCAATGTGCAGGGAGATGAACCCTTAATTCCCCC
ATCCGTCATTATACAGGTTGCGACTAACCTGCAGCAAAACAGTGCTGCTAGTGTGGCAACATTAAGTGCACCGATTGAAG
ACGTTGCCGATGTTTTTAATACTAATGCCGTAAAAGTGGTTTGTGATAAAAATAATATGGCGTTATATTTCAGTCGCGCC
ACCATTCCATGGAATCGTGATGATTTCAGTGTCGAAAATCAGGCTGAAAAATCCGTAGATTTTACTGCTTTACAACGTCA
TATTGGTATTTATGCCTACCGCGCTAGTTTTCTCAGGCAGTATGCAACGTTATCCGTTTCACCGCTGGAACTGCTCGAGA
AGCTGGAGCAGCTGCGTGTATTATGGCATGGTTTTAAAATTCACGTTGAGCAGGCAAATAAAATCCCACCACCTGGAATC
GATACTCAGGATGATTTGCAGCGTGTTATTGATTGTTTATCGCACTAG

Upstream 100 bases:

>100_bases
CTTATTTGTAAGTTTGATCATCTTGCCTACCCCGTTATTGACGGGATCCCTGCTCTGTTGAAAGTCAAAGCGCGTACCAT
CTCGTCCGATGAGGAGTAAT

Downstream 100 bases:

>100_bases
GAAACGCAATGAAAACTAACATGTTATTTATTTTAGGGCTGAGTTTTTTGCTTCTCGCCTGCGGAGACGAGCGTCCCGAA
AAACTTCAGGCTAATACTCG

Product: 3-deoxy-D-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSFIVVIPARYHSTRLPAKPLLDILGQTMIERVTNQALKSGAKQVIVATDDQRIVDALKHLNEIDVCMTSKDHQSGTDRL
AEVCQQFKLADDEIIVNVQGDEPLIPPSVIIQVATNLQQNSAASVATLSAPIEDVADVFNTNAVKVVCDKNNMALYFSRA
TIPWNRDDFSVENQAEKSVDFTALQRHIGIYAYRASFLRQYATLSVSPLELLEKLEQLRVLWHGFKIHVEQANKIPPPGI
DTQDDLQRVIDCLSH

Sequences:

>Translated_255_residues
MSFIVVIPARYHSTRLPAKPLLDILGQTMIERVTNQALKSGAKQVIVATDDQRIVDALKHLNEIDVCMTSKDHQSGTDRL
AEVCQQFKLADDEIIVNVQGDEPLIPPSVIIQVATNLQQNSAASVATLSAPIEDVADVFNTNAVKVVCDKNNMALYFSRA
TIPWNRDDFSVENQAEKSVDFTALQRHIGIYAYRASFLRQYATLSVSPLELLEKLEQLRVLWHGFKIHVEQANKIPPPGI
DTQDDLQRVIDCLSH
>Mature_254_residues
SFIVVIPARYHSTRLPAKPLLDILGQTMIERVTNQALKSGAKQVIVATDDQRIVDALKHLNEIDVCMTSKDHQSGTDRLA
EVCQQFKLADDEIIVNVQGDEPLIPPSVIIQVATNLQQNSAASVATLSAPIEDVADVFNTNAVKVVCDKNNMALYFSRAT
IPWNRDDFSVENQAEKSVDFTALQRHIGIYAYRASFLRQYATLSVSPLELLEKLEQLRVLWHGFKIHVEQANKIPPPGID
TQDDLQRVIDCLSH

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=249, Percent_Identity=54.6184738955823, Blast_Score=269, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_PSYIN (A1STD0)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942344.1
- ProteinModelPortal:   A1STD0
- SMR:   A1STD0
- STRING:   A1STD0
- GeneID:   4624391
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0903
- eggNOG:   COG1212
- HOGENOM:   HBG637773
- OMA:   FSRAPLP
- PhylomeDB:   A1STD0
- BioCyc:   PING357804:PING_0903-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 28486; Mature: 28355

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFIVVIPARYHSTRLPAKPLLDILGQTMIERVTNQALKSGAKQVIVATDDQRIVDALKH
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
LNEIDVCMTSKDHQSGTDRLAEVCQQFKLADDEIIVNVQGDEPLIPPSVIIQVATNLQQN
CCHHHHEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCC
SAASVATLSAPIEDVADVFNTNAVKVVCDKNNMALYFSRATIPWNRDDFSVENQAEKSVD
CCCCHHHHHCCHHHHHHHHCCCCEEEEECCCCEEEEEEEEECCCCCCCCCCCCHHHHHHH
FTALQRHIGIYAYRASFLRQYATLSVSPLELLEKLEQLRVLWHGFKIHVEQANKIPPPGI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCC
DTQDDLQRVIDCLSH
CCHHHHHHHHHHHCC
>Mature Secondary Structure 
SFIVVIPARYHSTRLPAKPLLDILGQTMIERVTNQALKSGAKQVIVATDDQRIVDALKH
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
LNEIDVCMTSKDHQSGTDRLAEVCQQFKLADDEIIVNVQGDEPLIPPSVIIQVATNLQQN
CCHHHHEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCC
SAASVATLSAPIEDVADVFNTNAVKVVCDKNNMALYFSRATIPWNRDDFSVENQAEKSVD
CCCCHHHHHCCHHHHHHHHCCCCEEEEECCCCEEEEEEEEECCCCCCCCCCCCHHHHHHH
FTALQRHIGIYAYRASFLRQYATLSVSPLELLEKLEQLRVLWHGFKIHVEQANKIPPPGI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCC
DTQDDLQRVIDCLSH
CCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA