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The map label for this gene is rfbD [C]

Identifier: 119944553

GI number: 119944553

Start: 989941

End: 990828

Strand: Direct

Name: rfbD [C]

Synonym: Ping_0790

Alternate gene names: 119944553

Gene position: 989941-990828 (Clockwise)

Preceding gene: 119944552

Following gene: 119944554

Centisome position: 21.71

GC content: 34.8

Gene sequence:

>888_bases
ATGAAAGTTTTGATTATTGGTGCAACAGGTATGCTAGGTTATAGCCTATTCCAGAACCTTTGTGATGTAGCTCATTTAGA
TGTTTATGGAACAGTTCGCAGCATTAAAGGGAAAGAGCCGTTCTTTAGTGATTGCGAAGAGCGGCTTTTTAAAGGCGTTG
ATGTTAGCGATTTAGCGGCAGTAGAGGCGGTTATTAAGGAAATCAAACCTGATGTTGTTATTAACTGTATTGGTTTGATT
AAACAACATAGCATTTCAAAGCAGCATGTTGATGCAGTGGCTATTAATAGTTTGTTGCCTCATCAGCTTGCAAGTTTATG
CGATAGTCATTCTTGCAAATTAATTCATTTTTCTACTGATTGCATTTTTGATGGGAAAAAAGGTTTTTACACAGAAGAAG
ATACACCTGATGCGCTAGACTTATATGGACGCTCAAAATGTTTAGGTGAAGTTGATTCTTCTCCTCATCTTACGCTTCGA
ACTTCAATCATAGGTCATGAGTTAGATTCGGCTGTGAGTTTAGTTGATTGGTTTTTATCACAAGAAAACAGTACAAAAGG
ATTTTCTAAAGCGATATTCTCTGGTCTTCCTACTTGTGTTATCGCTCGATTACTTATTGAAAAAATACTGCCTGCAAGTG
ACTTATCTGGATTGTATCAATTAAGTGTTGACCCTATAGACAAATTCACATTATTGAACCTTGTTGCTGATATATATAAT
AAAAAGATAGAAATAATTGAGTCAAAAGAGTTAAAAATAGACCGTTCATTAAACTCGAAAAAATTACGCGATGCATTAAG
CTTAGAAATCCCTTCTTGGAAGTCGCTTATTTCTGAAATGCATAATGACTATGAAAATCGATATGAGAAATACAGATGCA
AAAATTAA

Upstream 100 bases:

>100_bases
AGAACGTTTAGATGTTGAGGGAATGAAGACCTTATTACGTAAACTCGATTTTATGCGTGATATCGAGAGTGGTAATCTAA
CTGTTCCAGAAGGTGTATAA

Downstream 100 bases:

>100_bases
AAGTAGCCACTATTGTTGGTACTCGCCCAGAGATTATCCGTTTATCCAGAACAATCACCAAATTAGATAAATATTGTGAT
CACACCTTAATTCATACAGG

Product: dTDP-4-dehydrorhamnose reductase

Products: dTDP-4-dehydro-6-deoxy-L-mannose; NADPH; H+

Alternate protein names: Carbohydrate Oxidoreductase; NAD-Dependent Epimerase/Dehydratase; Dtdp-4-Dehydrorhamnose Reductase; Reductase; DTDP-4-Keto-L-Rhamnose Reductase; LPS Biosynthesis Related Reductase; DTDP-6-Deoxy-L-Mannose-Dehydrogenase; NAD Dependent Epimerase/Dehydratase Family Protein; DTDP-6-Deoxy-L-Mannose Dehydrogenase RmlD; Sugar Oxidoreductase; NAD Dependent Epimerase/Dehydratase; TDP-4-Keto-L-Rhamnose Reductase.; DTDP 4-Dehydrorhamnose Reductase

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MKVLIIGATGMLGYSLFQNLCDVAHLDVYGTVRSIKGKEPFFSDCEERLFKGVDVSDLAAVEAVIKEIKPDVVINCIGLI
KQHSISKQHVDAVAINSLLPHQLASLCDSHSCKLIHFSTDCIFDGKKGFYTEEDTPDALDLYGRSKCLGEVDSSPHLTLR
TSIIGHELDSAVSLVDWFLSQENSTKGFSKAIFSGLPTCVIARLLIEKILPASDLSGLYQLSVDPIDKFTLLNLVADIYN
KKIEIIESKELKIDRSLNSKKLRDALSLEIPSWKSLISEMHNDYENRYEKYRCKN

Sequences:

>Translated_295_residues
MKVLIIGATGMLGYSLFQNLCDVAHLDVYGTVRSIKGKEPFFSDCEERLFKGVDVSDLAAVEAVIKEIKPDVVINCIGLI
KQHSISKQHVDAVAINSLLPHQLASLCDSHSCKLIHFSTDCIFDGKKGFYTEEDTPDALDLYGRSKCLGEVDSSPHLTLR
TSIIGHELDSAVSLVDWFLSQENSTKGFSKAIFSGLPTCVIARLLIEKILPASDLSGLYQLSVDPIDKFTLLNLVADIYN
KKIEIIESKELKIDRSLNSKKLRDALSLEIPSWKSLISEMHNDYENRYEKYRCKN
>Mature_295_residues
MKVLIIGATGMLGYSLFQNLCDVAHLDVYGTVRSIKGKEPFFSDCEERLFKGVDVSDLAAVEAVIKEIKPDVVINCIGLI
KQHSISKQHVDAVAINSLLPHQLASLCDSHSCKLIHFSTDCIFDGKKGFYTEEDTPDALDLYGRSKCLGEVDSSPHLTLR
TSIIGHELDSAVSLVDWFLSQENSTKGFSKAIFSGLPTCVIARLLIEKILPASDLSGLYQLSVDPIDKFTLLNLVADIYN
KKIEIIESKELKIDRSLNSKKLRDALSLEIPSWKSLISEMHNDYENRYEKYRCKN

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG1091

COG function: function code M; dTDP-4-dehydrorhamnose reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.133

Molecular weight: Translated: 32945; Mature: 32945

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLIIGATGMLGYSLFQNLCDVAHLDVYGTVRSIKGKEPFFSDCEERLFKGVDVSDLAA
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHH
VEAVIKEIKPDVVINCIGLIKQHSISKQHVDAVAINSLLPHQLASLCDSHSCKLIHFSTD
HHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
CIFDGKKGFYTEEDTPDALDLYGRSKCLGEVDSSPHLTLRTSIIGHELDSAVSLVDWFLS
EEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHC
QENSTKGFSKAIFSGLPTCVIARLLIEKILPASDLSGLYQLSVDPIDKFTLLNLVADIYN
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHC
KKIEIIESKELKIDRSLNSKKLRDALSLEIPSWKSLISEMHNDYENRYEKYRCKN
CCEEEEECCCEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVLIIGATGMLGYSLFQNLCDVAHLDVYGTVRSIKGKEPFFSDCEERLFKGVDVSDLAA
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHH
VEAVIKEIKPDVVINCIGLIKQHSISKQHVDAVAINSLLPHQLASLCDSHSCKLIHFSTD
HHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
CIFDGKKGFYTEEDTPDALDLYGRSKCLGEVDSSPHLTLRTSIIGHELDSAVSLVDWFLS
EEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHC
QENSTKGFSKAIFSGLPTCVIARLLIEKILPASDLSGLYQLSVDPIDKFTLLNLVADIYN
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHC
KKIEIIESKELKIDRSLNSKKLRDALSLEIPSWKSLISEMHNDYENRYEKYRCKN
CCEEEEECCCEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTDP-6-deoxy-L-mannose; NADP+

Specific reaction: dTDP-6-deoxy-L-mannose + NADP+ = dTDP-4-dehydro-6-deoxy-L-mannose + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA