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The map label for this gene is dctD [H]

Identifier: 119944483

GI number: 119944483

Start: 905106

End: 906446

Strand: Reverse

Name: dctD [H]

Synonym: Ping_0712

Alternate gene names: 119944483

Gene position: 906446-905106 (Counterclockwise)

Preceding gene: 119944484

Following gene: 119944471

Centisome position: 19.88

GC content: 43.48

Gene sequence:

>1341_bases
ATGAATCCGGTTTTTTTTATTGATGATGAATATGATTTATGCAGCGCAAGTGAACAAACCTTTGAATTGGCAGAGATTGA
GGCGCGCTTTTTTAGCGATGCCGAGTCTGCGTTATTAGCAATGAAAAACACACTTCCGGTGGTTGTGATAACGGATATCC
GTTTACCGGGTTTATCTGGCCAGCAATTATTAACCACGCTGCACCAGCGAGATCCGGACTTGCCGGTTATTCTAATCACC
GGACATGGTGATATTTCAATGGCGGTTCAGGCGATTCGCGCCGGCGCTTATGATTTCATCGAAAAACCTTTTTTATCGGA
CAGGTTAATTGAAACCACCCGTAAAGCCATTGAAAAACGCCAGCTTACCCTGGAGAATCGCGATCTTAAAAAAGCACTGC
AAAGTAAAGAAACACTGGGTCCACGTATTATTGGTCATACCCCGAGTATTATTTTACTAAAGAAAATGGTCAGCCAAGTT
GCTGATAGCCAGGCCGATATTTTATTATTTGGCGAAACCGGCACAGGTAAAGAATTAGTCGCACGCTCCCTGCATGAGCA
AAGTCAGCGTAATACAAAAAACTTTGTCGCGGTTAATTGTGGCGCGATACCGGAAAATCTTATCGAAAGTGAACTTTACG
GACATGAAAAAGGCGCGTTCACCGGGGCAGGTACGCAGCGTATAGGAAAGTTTGAGTATGCGCAGGGGGGAACTCTTTTT
CTCGATGAAATTGAGTCCATGCCGATGCAGGCACAAGTGCGTTTGTTAAGAGTATTGCAGGAACGCAGTTTAGAACGTAT
TGGCTCAAACAAGGCAATTTCCTTAGATATCCGTATTATCGCTGCCACCAAAATAGATTTAAAAACGGCCCCTGATTTCA
GACAAGATTTGTATTACAGGCTAAATGTTGTCACTCTTGATTTACCCACTTTAAAACAACGCAAAGAAGATATTCCGACC
TTATTTCATCACTTTTTATTAGTTGCAGCAGCGCGTTACGGTAAAGCTGCTCCCGCGCTTCCGGCGAATGCGCTACAGGC
ATTATTAGCCCATGACTGGCCGGGAAATGTGCGCGAGCTAAGAAATGCGGCCGAACGTTTTATTTTACTCGGATCATTAA
CCGGATTAAATAACGATAATAACGTTGCCGATAGCGGCTTAAGTTTATCAGCTCAGGTAGAAGCATTTGAAAAAGCCTTA
ATAGAACAGGCGCTAAGTGTCACTGGCGGCAGCATTAAAGAGACGATGACCACACTCAATTTGGCGCGTAAAACCCTTTA
CGATAAAATGCAAAAACACGATTTGGAAAAACAAAATTATAAAGAGCCGGAACGCTCTTAA

Upstream 100 bases:

>100_bases
AATATGATTTACGTAGCGCAAGTGAACAAACTTTTGAATTGGCAGAGATTGATGCGCGCTTTTTGAGCGATGCCGAGTAT
TACAGCATTAAGGAAGAGTT

Downstream 100 bases:

>100_bases
ACTGCGCGAAGCAGCCGCTTTATGGTGCAAGTTATTCTTCAAGGCAAGGCAGGGTCAATTCAGGATAATAACAATATACT
TCTACGCCTGCTTTTTTAGC

Product: C4-dicarboxylate transport sigma-54 regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MNPVFFIDDEYDLCSASEQTFELAEIEARFFSDAESALLAMKNTLPVVVITDIRLPGLSGQQLLTTLHQRDPDLPVILIT
GHGDISMAVQAIRAGAYDFIEKPFLSDRLIETTRKAIEKRQLTLENRDLKKALQSKETLGPRIIGHTPSIILLKKMVSQV
ADSQADILLFGETGTGKELVARSLHEQSQRNTKNFVAVNCGAIPENLIESELYGHEKGAFTGAGTQRIGKFEYAQGGTLF
LDEIESMPMQAQVRLLRVLQERSLERIGSNKAISLDIRIIAATKIDLKTAPDFRQDLYYRLNVVTLDLPTLKQRKEDIPT
LFHHFLLVAAARYGKAAPALPANALQALLAHDWPGNVRELRNAAERFILLGSLTGLNNDNNVADSGLSLSAQVEAFEKAL
IEQALSVTGGSIKETMTTLNLARKTLYDKMQKHDLEKQNYKEPERS

Sequences:

>Translated_446_residues
MNPVFFIDDEYDLCSASEQTFELAEIEARFFSDAESALLAMKNTLPVVVITDIRLPGLSGQQLLTTLHQRDPDLPVILIT
GHGDISMAVQAIRAGAYDFIEKPFLSDRLIETTRKAIEKRQLTLENRDLKKALQSKETLGPRIIGHTPSIILLKKMVSQV
ADSQADILLFGETGTGKELVARSLHEQSQRNTKNFVAVNCGAIPENLIESELYGHEKGAFTGAGTQRIGKFEYAQGGTLF
LDEIESMPMQAQVRLLRVLQERSLERIGSNKAISLDIRIIAATKIDLKTAPDFRQDLYYRLNVVTLDLPTLKQRKEDIPT
LFHHFLLVAAARYGKAAPALPANALQALLAHDWPGNVRELRNAAERFILLGSLTGLNNDNNVADSGLSLSAQVEAFEKAL
IEQALSVTGGSIKETMTTLNLARKTLYDKMQKHDLEKQNYKEPERS
>Mature_446_residues
MNPVFFIDDEYDLCSASEQTFELAEIEARFFSDAESALLAMKNTLPVVVITDIRLPGLSGQQLLTTLHQRDPDLPVILIT
GHGDISMAVQAIRAGAYDFIEKPFLSDRLIETTRKAIEKRQLTLENRDLKKALQSKETLGPRIIGHTPSIILLKKMVSQV
ADSQADILLFGETGTGKELVARSLHEQSQRNTKNFVAVNCGAIPENLIESELYGHEKGAFTGAGTQRIGKFEYAQGGTLF
LDEIESMPMQAQVRLLRVLQERSLERIGSNKAISLDIRIIAATKIDLKTAPDFRQDLYYRLNVVTLDLPTLKQRKEDIPT
LFHHFLLVAAARYGKAAPALPANALQALLAHDWPGNVRELRNAAERFILLGSLTGLNNDNNVADSGLSLSAQVEAFEKAL
IEQALSVTGGSIKETMTTLNLARKTLYDKMQKHDLEKQNYKEPERS

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=455, Percent_Identity=37.8021978021978, Blast_Score=305, Evalue=4e-84,
Organism=Escherichia coli, GI1790299, Length=469, Percent_Identity=39.0191897654584, Blast_Score=295, Evalue=3e-81,
Organism=Escherichia coli, GI1790437, Length=442, Percent_Identity=38.9140271493213, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI1788905, Length=404, Percent_Identity=39.3564356435644, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1789087, Length=332, Percent_Identity=43.9759036144578, Blast_Score=251, Evalue=5e-68,
Organism=Escherichia coli, GI87082117, Length=333, Percent_Identity=43.8438438438438, Blast_Score=245, Evalue=4e-66,
Organism=Escherichia coli, GI1789233, Length=320, Percent_Identity=39.6875, Blast_Score=224, Evalue=9e-60,
Organism=Escherichia coli, GI1786524, Length=260, Percent_Identity=43.4615384615385, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI87082152, Length=236, Percent_Identity=44.9152542372881, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=41.1255411255411, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1787583, Length=228, Percent_Identity=39.0350877192982, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI87081858, Length=305, Percent_Identity=30.1639344262295, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1789828, Length=246, Percent_Identity=36.1788617886179, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49563; Mature: 49563

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPVFFIDDEYDLCSASEQTFELAEIEARFFSDAESALLAMKNTLPVVVITDIRLPGLSG
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCH
QQLLTTLHQRDPDLPVILITGHGDISMAVQAIRAGAYDFIEKPFLSDRLIETTRKAIEKR
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHH
QLTLENRDLKKALQSKETLGPRIIGHTPSIILLKKMVSQVADSQADILLFGETGTGKELV
HHHHCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHH
ARSLHEQSQRNTKNFVAVNCGAIPENLIESELYGHEKGAFTGAGTQRIGKFEYAQGGTLF
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHCCEEECCCCEEE
LDEIESMPMQAQVRLLRVLQERSLERIGSNKAISLDIRIIAATKIDLKTAPDFRQDLYYR
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEECCCCCCHHHHHEEE
LNVVTLDLPTLKQRKEDIPTLFHHFLLVAAARYGKAAPALPANALQALLAHDWPGNVREL
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHH
RNAAERFILLGSLTGLNNDNNVADSGLSLSAQVEAFEKALIEQALSVTGGSIKETMTTLN
HHHHHHEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LARKTLYDKMQKHDLEKQNYKEPERS
HHHHHHHHHHHHHCCCHHCCCCCCCC
>Mature Secondary Structure
MNPVFFIDDEYDLCSASEQTFELAEIEARFFSDAESALLAMKNTLPVVVITDIRLPGLSG
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCH
QQLLTTLHQRDPDLPVILITGHGDISMAVQAIRAGAYDFIEKPFLSDRLIETTRKAIEKR
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHH
QLTLENRDLKKALQSKETLGPRIIGHTPSIILLKKMVSQVADSQADILLFGETGTGKELV
HHHHCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHH
ARSLHEQSQRNTKNFVAVNCGAIPENLIESELYGHEKGAFTGAGTQRIGKFEYAQGGTLF
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHCCEEECCCCEEE
LDEIESMPMQAQVRLLRVLQERSLERIGSNKAISLDIRIIAATKIDLKTAPDFRQDLYYR
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEECCCCCCHHHHHEEE
LNVVTLDLPTLKQRKEDIPTLFHHFLLVAAARYGKAAPALPANALQALLAHDWPGNVREL
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHH
RNAAERFILLGSLTGLNNDNNVADSGLSLSAQVEAFEKALIEQALSVTGGSIKETMTTLN
HHHHHHEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LARKTLYDKMQKHDLEKQNYKEPERS
HHHHHHHHHHHHHCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]