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The map label for this gene is add [H]

Identifier: 119944464

GI number: 119944464

Start: 881628

End: 882635

Strand: Direct

Name: add [H]

Synonym: Ping_0692

Alternate gene names: 119944464

Gene position: 881628-882635 (Clockwise)

Preceding gene: 119944461

Following gene: 119944465

Centisome position: 19.34

GC content: 40.28

Gene sequence:

>1008_bases
ATGTCAGAAATAAATTTTGATTGGTTAAATGCATTACCAAAAGTTGAATTACACCTGCACTTAGAGGGCAGTTTAGAGCC
AGAGTTAATGTTTACACTGGCAAAACGTAATAATGTGAAGATCCCTTTTACGTCCGTTGAGCAGATTAAAGAAGCCTACC
AATTTAATAATCTGCAGGACTTTTTAGATATCTATTATCAAGGCGCAGACGTCTTGGTCGTTGAGCAGGATTTTTATGAT
TTAACCTGGGCTTATTTATTGAAATGTCAGCAACAAAATGTATTGCATGTTGAACCATTTTTTGATCCGCAAACCCATAC
GGCACGCGGTATTGATTTTTCAACCATTATCGATGGGATAAACCGTGCATTAGTTGATGGACGTGAAAAATTAGGTATCA
GCAGTGAATTAATACTGTGTTTTTTACGTCATCTTAGCGAAGATGACGCCTTTATTACATTACAACAGGCCATCCCCCAT
TTAGATAAAATTAAGGCAGTTGGTTTAGACAGCTCGGAAAAAGGGCATCCGCCGGAAAAATTCAGTCGAGTATTTGCCAA
AGCGCGGGAGCTGGGATTATTAACCGTGGCCCATGCGGGAGAGGAGGGGCCTGCTGAGTATATTTGGACTGCGCTTAATG
ATTTAAAAGTATCACGTGTTGATCATGGTGTCAGTGCCATTTTCGATAAGGCGCTGATGGAGTATTTAATTGCGGCACAG
ATGCCGCTAACGATTTGCCCGTTATCCAATACCAAGTTGAAAGTGTTTGCTGATATGTCTGAGCATACTATTTTACAAAT
GTTGGAACTGGGTGTTTGTGTGACGGTCAATTCTGATGATCCTGCCTATTTCGGCGGTTATATGACCGAAAACTTTGTTG
TCTTGAGGGATTCATTAGCCATGACAAAAGCACAAGCAAAACGGCTAGTGAGCAATAGTATTAAGGGCAGTTTTACCTCG
CTTGAATATAAAAACACAATGCAGCAACAACTTGCTGATTATCGTTAA

Upstream 100 bases:

>100_bases
ATGCTGGAAGATGATTTATCAATAAAAGCTAAGCTACAACAAGAGTCAAAACTTAAAGCGTTAAGCTTATAATAATAAAA
ATGAGAAGGTGAACGTAAGT

Downstream 100 bases:

>100_bases
TTATTATGGACTAATGTTATTAGTCAGTTTTTAAGTTTTTACTGCTTTAATCAAGTAAGGCTCAATGCATTAAAAGCAAA
GCCATTAAGCTATCTGATTA

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSEINFDWLNALPKVELHLHLEGSLEPELMFTLAKRNNVKIPFTSVEQIKEAYQFNNLQDFLDIYYQGADVLVVEQDFYD
LTWAYLLKCQQQNVLHVEPFFDPQTHTARGIDFSTIIDGINRALVDGREKLGISSELILCFLRHLSEDDAFITLQQAIPH
LDKIKAVGLDSSEKGHPPEKFSRVFAKARELGLLTVAHAGEEGPAEYIWTALNDLKVSRVDHGVSAIFDKALMEYLIAAQ
MPLTICPLSNTKLKVFADMSEHTILQMLELGVCVTVNSDDPAYFGGYMTENFVVLRDSLAMTKAQAKRLVSNSIKGSFTS
LEYKNTMQQQLADYR

Sequences:

>Translated_335_residues
MSEINFDWLNALPKVELHLHLEGSLEPELMFTLAKRNNVKIPFTSVEQIKEAYQFNNLQDFLDIYYQGADVLVVEQDFYD
LTWAYLLKCQQQNVLHVEPFFDPQTHTARGIDFSTIIDGINRALVDGREKLGISSELILCFLRHLSEDDAFITLQQAIPH
LDKIKAVGLDSSEKGHPPEKFSRVFAKARELGLLTVAHAGEEGPAEYIWTALNDLKVSRVDHGVSAIFDKALMEYLIAAQ
MPLTICPLSNTKLKVFADMSEHTILQMLELGVCVTVNSDDPAYFGGYMTENFVVLRDSLAMTKAQAKRLVSNSIKGSFTS
LEYKNTMQQQLADYR
>Mature_334_residues
SEINFDWLNALPKVELHLHLEGSLEPELMFTLAKRNNVKIPFTSVEQIKEAYQFNNLQDFLDIYYQGADVLVVEQDFYDL
TWAYLLKCQQQNVLHVEPFFDPQTHTARGIDFSTIIDGINRALVDGREKLGISSELILCFLRHLSEDDAFITLQQAIPHL
DKIKAVGLDSSEKGHPPEKFSRVFAKARELGLLTVAHAGEEGPAEYIWTALNDLKVSRVDHGVSAIFDKALMEYLIAAQM
PLTICPLSNTKLKVFADMSEHTILQMLELGVCVTVNSDDPAYFGGYMTENFVVLRDSLAMTKAQAKRLVSNSIKGSFTSL
EYKNTMQQQLADYR

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=331, Percent_Identity=24.4712990936556, Blast_Score=105, Evalue=5e-23,
Organism=Escherichia coli, GI1787910, Length=326, Percent_Identity=26.3803680981595, Blast_Score=140, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI32565969, Length=346, Percent_Identity=22.5433526011561, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538512, Length=346, Percent_Identity=22.5433526011561, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324188, Length=333, Percent_Identity=44.7447447447448, Blast_Score=291, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24645260, Length=339, Percent_Identity=23.598820058997, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 37887; Mature: 37756

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEINFDWLNALPKVELHLHLEGSLEPELMFTLAKRNNVKIPFTSVEQIKEAYQFNNLQD
CCCCCCHHHCCCCCEEEEEEECCCCCHHHEEEEECCCCEECCCHHHHHHHHHHHCCCHHH
FLDIYYQGADVLVVEQDFYDLTWAYLLKCQQQNVLHVEPFFDPQTHTARGIDFSTIIDGI
HHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
NRALVDGREKLGISSELILCFLRHLSEDDAFITLQQAIPHLDKIKAVGLDSSEKGHPPEK
HHHHHCCHHHCCCCHHHHHHHHHHCCCCCCEEEHHHHCCCHHHHHEECCCCCCCCCCHHH
FSRVFAKARELGLLTVAHAGEEGPAEYIWTALNDLKVSRVDHGVSAIFDKALMEYLIAAQ
HHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MPLTICPLSNTKLKVFADMSEHTILQMLELGVCVTVNSDDPAYFGGYMTENFVVLRDSLA
CCEEEECCCCCEEEEEECCHHHHHHHHHHCCEEEEECCCCCCEECCCCCCCEEEEEHHHH
MTKAQAKRLVSNSIKGSFTSLEYKNTMQQQLADYR
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEINFDWLNALPKVELHLHLEGSLEPELMFTLAKRNNVKIPFTSVEQIKEAYQFNNLQD
CCCCCHHHCCCCCEEEEEEECCCCCHHHEEEEECCCCEECCCHHHHHHHHHHHCCCHHH
FLDIYYQGADVLVVEQDFYDLTWAYLLKCQQQNVLHVEPFFDPQTHTARGIDFSTIIDGI
HHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
NRALVDGREKLGISSELILCFLRHLSEDDAFITLQQAIPHLDKIKAVGLDSSEKGHPPEK
HHHHHCCHHHCCCCHHHHHHHHHHCCCCCCEEEHHHHCCCHHHHHEECCCCCCCCCCHHH
FSRVFAKARELGLLTVAHAGEEGPAEYIWTALNDLKVSRVDHGVSAIFDKALMEYLIAAQ
HHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MPLTICPLSNTKLKVFADMSEHTILQMLELGVCVTVNSDDPAYFGGYMTENFVVLRDSLA
CCEEEECCCCCEEEEEECCHHHHHHHHHHCCEEEEECCCCCCEECCCCCCCEEEEEHHHH
MTKAQAKRLVSNSIKGSFTSLEYKNTMQQQLADYR
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA