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The map label for this gene is gluQ [H]

Identifier: 119944356

GI number: 119944356

Start: 762370

End: 763296

Strand: Reverse

Name: gluQ [H]

Synonym: Ping_0583

Alternate gene names: 119944356

Gene position: 763296-762370 (Counterclockwise)

Preceding gene: 119944357

Following gene: 119944355

Centisome position: 16.74

GC content: 44.23

Gene sequence:

>927_bases
TTGTTTATAAGCTATCTGTTTATAAGTTATTTTTTGCCTAAGCCCGTCATATATCGTGGACGCTTTGCTCCCTCGCCTTC
AGGTCCAATGCACTTTGGCTCTTTGGTCGCAGCATTAGGCAGTTATCTGCAGGCAAGATCTCAGCACGGATCATGGCAAG
TTCGTATTGATGATATTGATCCTCCCCGTGAAGTAAAAGGTGCCGCACAGGATATTCTCCTGACCCTGCAGGCTTACGGA
CTAAACTGGGATGGCGAAGTCATTTACCAAAGTCATAACAGCCAATCCTATGAAAATGTCCTAAGCCAACTGACAGAGCG
ACAACTCTGTTATGCATGCGCCTGCAGCCGTAAGATAATTCGCCAAAGTGGGGGACTTTATCAGGGCACCTGCCGGAATA
AACAGCTCCCGGAAATAAACCATGCACTGCGCATTAATTTATACAATATGACCCATCCTGTGACGTATTTTGATGATCAA
TTGCAGGGAAGTGTGGTATTAGATAAAAAACAAGCGACTGAAGATTTTATTATCAGGCGTAAAGAGGGCTTATATGCTTA
TAATCTGGCCACCGTCATAGATGATATCAATCAAGGTATTACAGAGATAGTACGCGGTGCTGATCTGCTCAACACCACGG
GTAAACAACTTACCTTATATCAGCTGCTAAATAAGAAACCACCCGGTTATTTACACTTGCCCGTCGCGGTGACAGCACCC
GGCAACAAACTTTCCAAACAAAACCATGCGTTAGCAATCAGTAAAGACAATCCAAGACCAACATTATTAGCAGCACTCCG
CTTTCTAGGGCACACTGTGCCCCAGGAAATGGCGCTAAATAGTTGCTTCGAAATACTGAAATGGGCAATACAAAACTGGT
CGCTGGACAAGCTCCCCCAGCTTGCTGAAATTCAAATAAAAAATTAA

Upstream 100 bases:

>100_bases
TATGCATTGACTGTAAAACATTAGCTGAAATCAAAGAGAGACAAATAGTTGGTTAACCCTCTTTTTGTTAAAAAAACGGT
TAGCCATTGGCTAGCCGTTT

Downstream 100 bases:

>100_bases
TTTGTCTTTCACCGCCCGCGCACATAAAATGGGTGCATATTTTGACACATATTGTAAAAATCAATCATTGAGGATAGCGT
TATTAAACGATTCAGTAAAT

Product: glutamate--tRNA ligase

Products: NA

Alternate protein names: Glu-Q-RSs [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MFISYLFISYFLPKPVIYRGRFAPSPSGPMHFGSLVAALGSYLQARSQHGSWQVRIDDIDPPREVKGAAQDILLTLQAYG
LNWDGEVIYQSHNSQSYENVLSQLTERQLCYACACSRKIIRQSGGLYQGTCRNKQLPEINHALRINLYNMTHPVTYFDDQ
LQGSVVLDKKQATEDFIIRRKEGLYAYNLATVIDDINQGITEIVRGADLLNTTGKQLTLYQLLNKKPPGYLHLPVAVTAP
GNKLSKQNHALAISKDNPRPTLLAALRFLGHTVPQEMALNSCFEILKWAIQNWSLDKLPQLAEIQIKN

Sequences:

>Translated_308_residues
MFISYLFISYFLPKPVIYRGRFAPSPSGPMHFGSLVAALGSYLQARSQHGSWQVRIDDIDPPREVKGAAQDILLTLQAYG
LNWDGEVIYQSHNSQSYENVLSQLTERQLCYACACSRKIIRQSGGLYQGTCRNKQLPEINHALRINLYNMTHPVTYFDDQ
LQGSVVLDKKQATEDFIIRRKEGLYAYNLATVIDDINQGITEIVRGADLLNTTGKQLTLYQLLNKKPPGYLHLPVAVTAP
GNKLSKQNHALAISKDNPRPTLLAALRFLGHTVPQEMALNSCFEILKWAIQNWSLDKLPQLAEIQIKN
>Mature_308_residues
MFISYLFISYFLPKPVIYRGRFAPSPSGPMHFGSLVAALGSYLQARSQHGSWQVRIDDIDPPREVKGAAQDILLTLQAYG
LNWDGEVIYQSHNSQSYENVLSQLTERQLCYACACSRKIIRQSGGLYQGTCRNKQLPEINHALRINLYNMTHPVTYFDDQ
LQGSVVLDKKQATEDFIIRRKEGLYAYNLATVIDDINQGITEIVRGADLLNTTGKQLTLYQLLNKKPPGYLHLPVAVTAP
GNKLSKQNHALAISKDNPRPTLLAALRFLGHTVPQEMALNSCFEILKWAIQNWSLDKLPQLAEIQIKN

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=254, Percent_Identity=31.1023622047244, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI226510925, Length=296, Percent_Identity=53.7162162162162, Blast_Score=311, Evalue=5e-86,
Organism=Escherichia coli, GI1788743, Length=245, Percent_Identity=31.0204081632653, Blast_Score=130, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI71993394, Length=268, Percent_Identity=30.9701492537313, Blast_Score=107, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6324540, Length=294, Percent_Identity=29.9319727891156, Blast_Score=122, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24665321, Length=260, Percent_Identity=29.6153846153846, Blast_Score=113, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: NA

Molecular weight: Translated: 34715; Mature: 34715

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFISYLFISYFLPKPVIYRGRFAPSPSGPMHFGSLVAALGSYLQARSQHGSWQVRIDDID
CHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PPREVKGAAQDILLTLQAYGLNWDGEVIYQSHNSQSYENVLSQLTERQLCYACACSRKII
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RQSGGLYQGTCRNKQLPEINHALRINLYNMTHPVTYFDDQLQGSVVLDKKQATEDFIIRR
HHCCCEEECCCCCCCCCCCCCEEEEEEEECCCCCEEECCCCCCCEEECCHHCHHHHHHHH
KEGLYAYNLATVIDDINQGITEIVRGADLLNTTGKQLTLYQLLNKKPPGYLHLPVAVTAP
CCCCEEEHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHCCCCCCEEEEEEEEECC
GNKLSKQNHALAISKDNPRPTLLAALRFLGHTVPQEMALNSCFEILKWAIQNWSLDKLPQ
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHCCC
LAEIQIKN
CCEEEECC
>Mature Secondary Structure
MFISYLFISYFLPKPVIYRGRFAPSPSGPMHFGSLVAALGSYLQARSQHGSWQVRIDDID
CHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PPREVKGAAQDILLTLQAYGLNWDGEVIYQSHNSQSYENVLSQLTERQLCYACACSRKII
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RQSGGLYQGTCRNKQLPEINHALRINLYNMTHPVTYFDDQLQGSVVLDKKQATEDFIIRR
HHCCCEEECCCCCCCCCCCCCEEEEEEEECCCCCEEECCCCCCCEEECCHHCHHHHHHHH
KEGLYAYNLATVIDDINQGITEIVRGADLLNTTGKQLTLYQLLNKKPPGYLHLPVAVTAP
CCCCEEEHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHCCCCCCEEEEEEEEECC
GNKLSKQNHALAISKDNPRPTLLAALRFLGHTVPQEMALNSCFEILKWAIQNWSLDKLPQ
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHCCC
LAEIQIKN
CCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA