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The map label for this gene is can [H]

Identifier: 119944170

GI number: 119944170

Start: 495945

End: 496574

Strand: Direct

Name: can [H]

Synonym: Ping_0390

Alternate gene names: 119944170

Gene position: 495945-496574 (Clockwise)

Preceding gene: 119944167

Following gene: 119944171

Centisome position: 10.88

GC content: 36.83

Gene sequence:

>630_bases
ATGAGTTTATTAGAAGCGCTATTAAAAAATAATGAAGAGTGGGCTGCAAAAATAAATGAAGAAGATCCTACTTTTTTTCC
GCGACTTGCTAATCGACAGTCCCCAGAATATCTCTGGATAGGTTGTTCTGACAGCCGTGTGCCCGCCAATCAGTTATTAG
GGTTATTTCCCGGGGACATATTCGTTCATCGTAATATTGCCAACCTTGTTGTGCATACTGATCTAAACTGCATGTCGGTT
ATTAAATATGCCGTGGATGTTTTAAAAGTTAAACATATTATAGTGACTGGGCATTATGATTGTGGTGGTATTCACGCAGC
AATGCAAAAGCAGTCTTTTGACTTGATTGATGGTTGGCTGCGCAATATCAAGGATATCTATGTGAAATTTAGTGATAGTT
TCACCGCAGAAATGACATATAAGCAACGTTTAGATTATCTTACTGAGCTTAATGTTATCGAACAGGCAAAAAATGTTTGT
CATACAACTTGTGTTCAGGAAGCCTGGGCAAATGGACAAGATTTGACGGTTCATGGATTTATTTATTCTGTGGTAGACGG
TCGCCTGAAAGATCTTAATGTGAATTTTGATAATTTAGAAAAAATAAATGATCTATATCATATCCGTTAA

Upstream 100 bases:

>100_bases
AAGTTATGTGATCTATTTTAATATGAACTCTGATAGGGTATAAGAATAAGTATTCCTCAAGTTCCTTGAGTGTCAATGCA
TATTAAATAGAAAGGTAAGT

Downstream 100 bases:

>100_bases
GCTCCCATTGTTTTAATCATTCCCTGCTGTTTAATAAGGAATGAGCTATAATGTCCGAAGTCTAAAAAAAGGAAATGTTA
ATGAAAAAATTATTACTTGC

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MSLLEALLKNNEEWAAKINEEDPTFFPRLANRQSPEYLWIGCSDSRVPANQLLGLFPGDIFVHRNIANLVVHTDLNCMSV
IKYAVDVLKVKHIIVTGHYDCGGIHAAMQKQSFDLIDGWLRNIKDIYVKFSDSFTAEMTYKQRLDYLTELNVIEQAKNVC
HTTCVQEAWANGQDLTVHGFIYSVVDGRLKDLNVNFDNLEKINDLYHIR

Sequences:

>Translated_209_residues
MSLLEALLKNNEEWAAKINEEDPTFFPRLANRQSPEYLWIGCSDSRVPANQLLGLFPGDIFVHRNIANLVVHTDLNCMSV
IKYAVDVLKVKHIIVTGHYDCGGIHAAMQKQSFDLIDGWLRNIKDIYVKFSDSFTAEMTYKQRLDYLTELNVIEQAKNVC
HTTCVQEAWANGQDLTVHGFIYSVVDGRLKDLNVNFDNLEKINDLYHIR
>Mature_208_residues
SLLEALLKNNEEWAAKINEEDPTFFPRLANRQSPEYLWIGCSDSRVPANQLLGLFPGDIFVHRNIANLVVHTDLNCMSVI
KYAVDVLKVKHIIVTGHYDCGGIHAAMQKQSFDLIDGWLRNIKDIYVKFSDSFTAEMTYKQRLDYLTELNVIEQAKNVCH
TTCVQEAWANGQDLTVHGFIYSVVDGRLKDLNVNFDNLEKINDLYHIR

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=206, Percent_Identity=53.3980582524272, Blast_Score=239, Evalue=8e-65,
Organism=Escherichia coli, GI1786534, Length=176, Percent_Identity=30.1136363636364, Blast_Score=78, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324292, Length=201, Percent_Identity=34.8258706467662, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23977; Mature: 23845

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLEALLKNNEEWAAKINEEDPTFFPRLANRQSPEYLWIGCSDSRVPANQLLGLFPGDI
CHHHHHHHCCCHHHEEECCCCCCCHHHHHCCCCCCCEEEEECCCCCCCHHHHHHCCCCCE
FVHRNIANLVVHTDLNCMSVIKYAVDVLKVKHIIVTGHYDCGGIHAAMQKQSFDLIDGWL
EEECCHHHEEEECCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHCCHHHHHHHH
RNIKDIYVKFSDSFTAEMTYKQRLDYLTELNVIEQAKNVCHTTCVQEAWANGQDLTVHGF
HHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHH
IYSVVDGRLKDLNVNFDNLEKINDLYHIR
HHHHHCCCCEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLLEALLKNNEEWAAKINEEDPTFFPRLANRQSPEYLWIGCSDSRVPANQLLGLFPGDI
HHHHHHHCCCHHHEEECCCCCCCHHHHHCCCCCCCEEEEECCCCCCCHHHHHHCCCCCE
FVHRNIANLVVHTDLNCMSVIKYAVDVLKVKHIIVTGHYDCGGIHAAMQKQSFDLIDGWL
EEECCHHHEEEECCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHCCHHHHHHHH
RNIKDIYVKFSDSFTAEMTYKQRLDYLTELNVIEQAKNVCHTTCVQEAWANGQDLTVHGF
HHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHH
IYSVVDGRLKDLNVNFDNLEKINDLYHIR
HHHHHCCCCEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]