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The map label for this gene is 119867149

Identifier: 119867149

GI number: 119867149

Start: 1184185

End: 1186224

Strand: Reverse

Name: 119867149

Synonym: Mkms_1097

Alternate gene names: NA

Gene position: 1186224-1184185 (Counterclockwise)

Preceding gene: 119867150

Following gene: 119867148

Centisome position: 20.68

GC content: 70.2

Gene sequence:

>2040_bases
ATGACCCGGACCCGCCCACCGCAGAGCCCTCGGCGCGTGTTCCGCGACCGCCGCGAGGCCGGTCGGGTGCTGGCGGACCT
GCTCACCGCATACCGCGGGCGAGATGACGTCATCGTGCTGGGGCTGGCACGCGGCGGTGTCCCGGTCGCGTGGGAGGTGG
CCGCGGCCCTCGGCGCTCCCCTGGACGCGTTCATCGTGCGCAAGCTGGGGGCGCCGGGGCATGAGGAGTTCGCGATGGGG
GCGCTGGCCACCGGCGGGCGCGTCGTGGTCAACGACGACATCGTGCGCGCGCTGCGCGTCAGCCCGCAGCAACTCCGAGA
CATCGCCGAGCGGGAAGGGCACGAGCTCTTCCGCAGGGAAGCCGCCTACCGGGCCGGGCGTCCCCCGCTCGACGTGTCCG
GGAAGACGGTCGTCCTCGTCGACGACGGGCTGGCGACCGGGGCCAGCATGATGGCGGCGATACAGGCCCTGCGTGACGCC
GGCCCGGCCGAGATCGTGGTCGCGGTGCCCGCCGCGCCGGAGTCGACCTGCCACGAGATACTCGGCGTCGCCGACGATCT
GGTCTGCGCGAGCATGCCGACGCCGTTCGTCGCTGTCGGTGAATCGTATTGGGATTTCCGACAGGTAAGCGACGAAGAAG
TCCGCGAGCACCTCGCCACCCCAACGACCGGCAGCGCCGCCACACCCGCGCCGGCCGCCCTGACACCGACCGCCATCGTG
GGTGGGTGTGCGGTGGACGCGCCGGGCGGCGTGCCGCCACTCGACGCGCTGGAAGCGATCGTCGGTGACGCCAGGGTGGT
CCTGATCGGCGAGGGCTCACACGGGACCCACGAGTTCTACGCTGCCCGCGCCGCGATCACCAGGTGGCTCATCGAGCAGA
AGGGCTTCTGCGCGGTCGCCGCGGAAGCCGACTGGCCCGACGCCTACCGGGTCAACCGGTACGTCCGCGGCGAGGGCGAG
GACACCACCGCCGACGCGGCGTTGCGCGGATTCCAGCGCTTCCCGGCGTGGATGTGGCGCAACGTGGTGGTGCGGGACTT
CGCCGAGTGGCTGCAGGCCCACAATCGGCAGCGCCGATCCCTCGGTCAGCGCCAGACCGGCTTCTACGGCCTGGACCTCT
ACAGCCTGCATCGCTCCATGGAAGAGGTGATCTCCTATCTCGACGGGGTGGACCCGCGCGCGGCAGATCGTGCGCGCCGC
CGTTACGCCTGCTTCGACCACGCGACCGCCGACGACGGTCAGGCCTACGGTTACGCCGCCGCCTTCGGCGCGGGTCTGTC
CTGTGAGCGTGAGGCGGTCGATCAGCTGATCGACATGCACCACAGCGCAATCGATTACCTCCACCACGACGGCCTGGTCG
CCGAGGACGAGTTGTTCTACGCCCAGCAGAACGCCCAGACCGTCCGCGACGCCGAGGTCTACTACCGGGCGATGTTCAGC
GGCCGTGTGACGTCGTGGAATCTGCGAGACGAACACATGGCCAGAACACTGGAGTCGCTGCTGACCCACCTCGATCGCCA
CCCCGGCGCGGGCCCGGCACGAATCGTGTTGTGGGCGCACAACTCCCACGTCGGTGACGCCAGGGCCACCGAGGTGTCCT
CCGACGGCCAGCTCACCCTGGGGCAGCTGGCGCGTCAACGGTTCGGCGACGACTGCCGCCTGATCGGCCTGACCACCTAC
ACGGGCACCGTCACCGCGGCCAGTGAGTGGGGCGGTGTCGCCGAGCGGAAGGTCGTCCGGCCTGCACTGAACGGCAGCGT
GGAAGAGCTGTTCCACGAAACCGATCGGCCGGAGTTCGTCATCTCGGCGTTGATCGACCGTGCCGCCGAGGAACCGCTGT
CGACGGTGCGGTTGGGCCGGGCGATCGGCGTCATCTACCTCCCGGCCACCGAGCGGCAGAGCCACTACTACCACGTGCGG
CCCGCCGATCAGTACGACGCCATCATCCACATCGACCGGACGCGGGCGCTCGAGCCGCTGGAGGTCACCAGCGAATGGGT
GGCGGGCGAGACCCCCGAGACGTATCCCAGCGGTTTGTGA

Upstream 100 bases:

>100_bases
TCACGGTGACCGTGCCGCTCAAGGAGCCCGCCAGCCCGGAGAAGCACGTCACGATCAAGTCGACGGACTGACCGTCCCGG
TCACGGATGAGCAGACGAGG

Downstream 100 bases:

>100_bases
ACCACCCGAAAACCCCTGAAAACCCTGCAATGCGGGACCTTCGACCCTGGCGCAGCGGACCAGGCCGTTCCTAGGGTCGA
GGTATGGGAAGGCAACGACC

Product: erythromycin esterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 679; Mature: 678

Protein sequence:

>679_residues
MTRTRPPQSPRRVFRDRREAGRVLADLLTAYRGRDDVIVLGLARGGVPVAWEVAAALGAPLDAFIVRKLGAPGHEEFAMG
ALATGGRVVVNDDIVRALRVSPQQLRDIAEREGHELFRREAAYRAGRPPLDVSGKTVVLVDDGLATGASMMAAIQALRDA
GPAEIVVAVPAAPESTCHEILGVADDLVCASMPTPFVAVGESYWDFRQVSDEEVREHLATPTTGSAATPAPAALTPTAIV
GGCAVDAPGGVPPLDALEAIVGDARVVLIGEGSHGTHEFYAARAAITRWLIEQKGFCAVAAEADWPDAYRVNRYVRGEGE
DTTADAALRGFQRFPAWMWRNVVVRDFAEWLQAHNRQRRSLGQRQTGFYGLDLYSLHRSMEEVISYLDGVDPRAADRARR
RYACFDHATADDGQAYGYAAAFGAGLSCEREAVDQLIDMHHSAIDYLHHDGLVAEDELFYAQQNAQTVRDAEVYYRAMFS
GRVTSWNLRDEHMARTLESLLTHLDRHPGAGPARIVLWAHNSHVGDARATEVSSDGQLTLGQLARQRFGDDCRLIGLTTY
TGTVTAASEWGGVAERKVVRPALNGSVEELFHETDRPEFVISALIDRAAEEPLSTVRLGRAIGVIYLPATERQSHYYHVR
PADQYDAIIHIDRTRALEPLEVTSEWVAGETPETYPSGL

Sequences:

>Translated_679_residues
MTRTRPPQSPRRVFRDRREAGRVLADLLTAYRGRDDVIVLGLARGGVPVAWEVAAALGAPLDAFIVRKLGAPGHEEFAMG
ALATGGRVVVNDDIVRALRVSPQQLRDIAEREGHELFRREAAYRAGRPPLDVSGKTVVLVDDGLATGASMMAAIQALRDA
GPAEIVVAVPAAPESTCHEILGVADDLVCASMPTPFVAVGESYWDFRQVSDEEVREHLATPTTGSAATPAPAALTPTAIV
GGCAVDAPGGVPPLDALEAIVGDARVVLIGEGSHGTHEFYAARAAITRWLIEQKGFCAVAAEADWPDAYRVNRYVRGEGE
DTTADAALRGFQRFPAWMWRNVVVRDFAEWLQAHNRQRRSLGQRQTGFYGLDLYSLHRSMEEVISYLDGVDPRAADRARR
RYACFDHATADDGQAYGYAAAFGAGLSCEREAVDQLIDMHHSAIDYLHHDGLVAEDELFYAQQNAQTVRDAEVYYRAMFS
GRVTSWNLRDEHMARTLESLLTHLDRHPGAGPARIVLWAHNSHVGDARATEVSSDGQLTLGQLARQRFGDDCRLIGLTTY
TGTVTAASEWGGVAERKVVRPALNGSVEELFHETDRPEFVISALIDRAAEEPLSTVRLGRAIGVIYLPATERQSHYYHVR
PADQYDAIIHIDRTRALEPLEVTSEWVAGETPETYPSGL
>Mature_678_residues
TRTRPPQSPRRVFRDRREAGRVLADLLTAYRGRDDVIVLGLARGGVPVAWEVAAALGAPLDAFIVRKLGAPGHEEFAMGA
LATGGRVVVNDDIVRALRVSPQQLRDIAEREGHELFRREAAYRAGRPPLDVSGKTVVLVDDGLATGASMMAAIQALRDAG
PAEIVVAVPAAPESTCHEILGVADDLVCASMPTPFVAVGESYWDFRQVSDEEVREHLATPTTGSAATPAPAALTPTAIVG
GCAVDAPGGVPPLDALEAIVGDARVVLIGEGSHGTHEFYAARAAITRWLIEQKGFCAVAAEADWPDAYRVNRYVRGEGED
TTADAALRGFQRFPAWMWRNVVVRDFAEWLQAHNRQRRSLGQRQTGFYGLDLYSLHRSMEEVISYLDGVDPRAADRARRR
YACFDHATADDGQAYGYAAAFGAGLSCEREAVDQLIDMHHSAIDYLHHDGLVAEDELFYAQQNAQTVRDAEVYYRAMFSG
RVTSWNLRDEHMARTLESLLTHLDRHPGAGPARIVLWAHNSHVGDARATEVSSDGQLTLGQLARQRFGDDCRLIGLTTYT
GTVTAASEWGGVAERKVVRPALNGSVEELFHETDRPEFVISALIDRAAEEPLSTVRLGRAIGVIYLPATERQSHYYHVRP
ADQYDAIIHIDRTRALEPLEVTSEWVAGETPETYPSGL

Specific function: Unknown

COG id: COG2312

COG function: function code R; Erythromycin esterase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007815
- InterPro:   IPR000836 [H]

Pfam domain/function: PF05139 Erythro_esteras; PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 74239; Mature: 74108

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTRPPQSPRRVFRDRREAGRVLADLLTAYRGRDDVIVLGLARGGVPVAWEVAAALGAP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCC
LDAFIVRKLGAPGHEEFAMGALATGGRVVVNDDIVRALRVSPQQLRDIAEREGHELFRRE
HHHHHHHHHCCCCHHHHHHHHCCCCCEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AAYRAGRPPLDVSGKTVVLVDDGLATGASMMAAIQALRDAGPAEIVVAVPAAPESTCHEI
HHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHH
LGVADDLVCASMPTPFVAVGESYWDFRQVSDEEVREHLATPTTGSAATPAPAALTPTAIV
HCCHHHHHHHCCCCCEEEECCCHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHC
GGCAVDAPGGVPPLDALEAIVGDARVVLIGEGSHGTHEFYAARAAITRWLIEQKGFCAVA
CCCEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
AEADWPDAYRVNRYVRGEGEDTTADAALRGFQRFPAWMWRNVVVRDFAEWLQAHNRQRRS
ECCCCCCHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGQRQTGFYGLDLYSLHRSMEEVISYLDGVDPRAADRARRRYACFDHATADDGQAYGYAA
CCCCCCCCEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHH
AFGAGLSCEREAVDQLIDMHHSAIDYLHHDGLVAEDELFYAQQNAQTVRDAEVYYRAMFS
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHC
GRVTSWNLRDEHMARTLESLLTHLDRHPGAGPARIVLWAHNSHVGDARATEVSSDGQLTL
CCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEH
GQLARQRFGDDCRLIGLTTYTGTVTAASEWGGVAERKVVRPALNGSVEELFHETDRPEFV
HHHHHHHCCCCEEEEEEEEECCEEEECHHCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHH
ISALIDRAAEEPLSTVRLGRAIGVIYLPATERQSHYYHVRPADQYDAIIHIDRTRALEPL
HHHHHHHHHHCHHHHHHHHHHEEEEEECCCCCCCCEEEECCCCCCCEEEEEECCCCCCCH
EVTSEWVAGETPETYPSGL
HHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TRTRPPQSPRRVFRDRREAGRVLADLLTAYRGRDDVIVLGLARGGVPVAWEVAAALGAP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCC
LDAFIVRKLGAPGHEEFAMGALATGGRVVVNDDIVRALRVSPQQLRDIAEREGHELFRRE
HHHHHHHHHCCCCHHHHHHHHCCCCCEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AAYRAGRPPLDVSGKTVVLVDDGLATGASMMAAIQALRDAGPAEIVVAVPAAPESTCHEI
HHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHH
LGVADDLVCASMPTPFVAVGESYWDFRQVSDEEVREHLATPTTGSAATPAPAALTPTAIV
HCCHHHHHHHCCCCCEEEECCCHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHC
GGCAVDAPGGVPPLDALEAIVGDARVVLIGEGSHGTHEFYAARAAITRWLIEQKGFCAVA
CCCEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
AEADWPDAYRVNRYVRGEGEDTTADAALRGFQRFPAWMWRNVVVRDFAEWLQAHNRQRRS
ECCCCCCHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGQRQTGFYGLDLYSLHRSMEEVISYLDGVDPRAADRARRRYACFDHATADDGQAYGYAA
CCCCCCCCEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHH
AFGAGLSCEREAVDQLIDMHHSAIDYLHHDGLVAEDELFYAQQNAQTVRDAEVYYRAMFS
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHC
GRVTSWNLRDEHMARTLESLLTHLDRHPGAGPARIVLWAHNSHVGDARATEVSSDGQLTL
CCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEH
GQLARQRFGDDCRLIGLTTYTGTVTAASEWGGVAERKVVRPALNGSVEELFHETDRPEFV
HHHHHHHCCCCEEEEEEEEECCEEEECHHCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHH
ISALIDRAAEEPLSTVRLGRAIGVIYLPATERQSHYYHVRPADQYDAIIHIDRTRALEPL
HHHHHHHHHHCHHHHHHHHHHEEEEEECCCCCCCCEEEECCCCCCCEEEEEECCCCCCCH
EVTSEWVAGETPETYPSGL
HHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]