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The map label for this gene is ctpG [H]

Identifier: 119855081

GI number: 119855081

Start: 203387

End: 205519

Strand: Direct

Name: ctpG [H]

Synonym: Mkms_5693

Alternate gene names: 119855081

Gene position: 203387-205519 (Clockwise)

Preceding gene: 119855080

Following gene: 119855082

Centisome position: 67.33

GC content: 67.56

Gene sequence:

>2133_bases
GTGTCTGATGCGTGCTGCGGGCCGCGCGACGACGCCGAACTCGACGCAGGTCCCGAGAAGCTTTGGCAAGTAAGAGAGTT
GCAGTTCGCGGTGCTCGCGGCGGTCCTGTTGAGCGTGGGCTGGATCGTGGGGCGGTTCGGCGGCTATGAGGGTGTCGTAG
AAGCCGTCGAGCTGGCGGCTGTAGCCGCCGGCGCCATCACGTTCGTGCCGGATGCGGCCCGTAACCTGCGACACGGTCGC
ATCGGGGTTGGCACGTTGATGACGATCGCCGCGATCGGCGCAGTCGCTCTGGGCCAATTCGCCGAGGCAGCACTGCTCGG
CATCCTGTTCTCAATCGCCGAAGGGCTGGAGCACTACGCCGTCAGCCGCACCCGCCGCGGGCTTCGCTCCCTGTTGTCTC
TTGTGCCGCCGAAAGCCTCGGTGCTACGGCACGGCACCGAAACAACCGTGGCCCCCGGCGAACTCGTCGTCGGTGACGTC
ATGGTGATCCGGCCTGGTGAACGGGCCGCCACTGATGGCACCATTCGGTCCGGTCAGACGAGCCTGGATCTGTCGGCGAT
CACGGGCGAGTCGCTGCCCGTCGAAGCCGGCCCCGGCAGCGACGTGTTCGCCGGTGCCATCAACGGCGGTGGAGCGATCG
AGGTGGAAGTCACCGCCCTGGCCGCCGACAGCTCATTAGCGCGCATCGTGCACATCGTCGAAGAAGCCCAAGAACGTAAA
GGCGCCGGTCAACGACTGGCCGACAGGATCGCCCGTCCGCTGGTGCCGGCGATCATGGCGTTGGCCGCGGCCATCGCCGC
GGTTGGCGCGGTGTTCGGTGACCCGATGCTGTGGCTGGAGCGGGCGCTGGTGGTGCTGGTGGCTGCCTCACCGTGCGCGC
TGGCGATCGCCGTCCCGCTGACCGTGGTCGCGGCCATCGGGGCCGCCAGCCGCCATGGCGCCCTGATCAAGGGCGGCGCC
GCAGTCGAAGAACTCGGCCGCATCAAGGTCGTCGCCCTGGACAAGACCGGCACCCTCACGCGCAACCAGCCCCGCGTCAT
CGACGTCATCACCACCGACGACTTCAGCGACGATGATGCCTTGAGGTGGGCAGCTGCGTTGGAGACACGCAGTGAACACC
CACTCGCACAAGCGATTCTGACTGCCGCCGGTGATCCGCCGATCGCCAGCGACGTGACCGCAGTGCCCGGCCATGGTCTG
CATGGTGAGCTCGACGGCTACCGGCTGCGCCTCGGTAAGCCCTCCTGGGTAACGCCTGGACCACTCGCCGACGACATCGA
GCGGTTGCAGGCAGCCGGCGCGACCGTGGTGGTGCTGGCCCGAGACGAACAGCCGGTCGCCGCCATCGCGGTGCGCGATG
AACTTCGCCCCGAAGCCGCCGACACCGTGCGGCTGCTTACACGCCTGGGCCTCACGGTGGCGATGCTCACCGGTGACAAC
GCCCGCACCGCCGAAGCAGTGGCCGCCGAGGCCGGCATCACGAACGTGCACTCCGAGCTGCTTCCCGAGGACAAAGCAGC
TCTACTGCGAACCATTGCACAAGGCCGCCCCATCGCCATGGTCGGCGACGGCATCAACGACGCCCCCGCGCTGGCCACCG
CCGACATCGGCATCGCCATGGGCGCCATGGGCACCGACGTCGCCATCGAAACCGCCGACGTCGCCCTGATGGGTGAAGAC
CTTCGCCACCTACCCCAGGTACTGGCCCACTCGCGGCGTGCCCGGGGAATCATGGTGCAGAACATCGCATTCTCGCTGGC
CATCATCGCCGTCCTGATACCGCTAGCCGCATTCGGTGTCCTGGGCTTGGCCACCGTGGTCCTGATCCACGAAACCGCCG
AAGTACTGGTCATCCTCAACGCCATCCGCGCCGCGCGCATCGCCGCCCTCCCTGGCGTGACAACGTCGTCGCCACGATCA
ACGACTCATGCCATCGACATCGGCCCGGCACCCACCCTCGACGACCCCTGCTGTGGTCCCCAACGGTCGACGCCGCCCTC
AGCCACCAAACTCAACTCCCCATTGGTCGCGGCAGATGTTGCACCAAACGACCACGGATGTGACTGCTGCGCTCCCGCCG
GACCTCCACTGGCCGACGACCCGACCGCATCCATAAGGGCCAACCACCGATAG

Upstream 100 bases:

>100_bases
CAGGGCAAGTTGGTGATGTACCAGCTGACCGAGCGTGGCCGCCAGCTGACCGACTCGGTGCTCGCCAGTGCGGTCGCGCT
TACGGGGAAGGAATCCGATT

Downstream 100 bases:

>100_bases
CCCACCACTTTCCGCACGACAGGAGTCGACTCGATGCCACGAATTGGCGAGCGTGCCCGGCGGGTCTATCGAGGTGAGAT
GACCGCTGCGAAATATGCGA

Product: heavy metal translocating P-type ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 710; Mature: 709

Protein sequence:

>710_residues
MSDACCGPRDDAELDAGPEKLWQVRELQFAVLAAVLLSVGWIVGRFGGYEGVVEAVELAAVAAGAITFVPDAARNLRHGR
IGVGTLMTIAAIGAVALGQFAEAALLGILFSIAEGLEHYAVSRTRRGLRSLLSLVPPKASVLRHGTETTVAPGELVVGDV
MVIRPGERAATDGTIRSGQTSLDLSAITGESLPVEAGPGSDVFAGAINGGGAIEVEVTALAADSSLARIVHIVEEAQERK
GAGQRLADRIARPLVPAIMALAAAIAAVGAVFGDPMLWLERALVVLVAASPCALAIAVPLTVVAAIGAASRHGALIKGGA
AVEELGRIKVVALDKTGTLTRNQPRVIDVITTDDFSDDDALRWAAALETRSEHPLAQAILTAAGDPPIASDVTAVPGHGL
HGELDGYRLRLGKPSWVTPGPLADDIERLQAAGATVVVLARDEQPVAAIAVRDELRPEAADTVRLLTRLGLTVAMLTGDN
ARTAEAVAAEAGITNVHSELLPEDKAALLRTIAQGRPIAMVGDGINDAPALATADIGIAMGAMGTDVAIETADVALMGED
LRHLPQVLAHSRRARGIMVQNIAFSLAIIAVLIPLAAFGVLGLATVVLIHETAEVLVILNAIRAARIAALPGVTTSSPRS
TTHAIDIGPAPTLDDPCCGPQRSTPPSATKLNSPLVAADVAPNDHGCDCCAPAGPPLADDPTASIRANHR

Sequences:

>Translated_710_residues
MSDACCGPRDDAELDAGPEKLWQVRELQFAVLAAVLLSVGWIVGRFGGYEGVVEAVELAAVAAGAITFVPDAARNLRHGR
IGVGTLMTIAAIGAVALGQFAEAALLGILFSIAEGLEHYAVSRTRRGLRSLLSLVPPKASVLRHGTETTVAPGELVVGDV
MVIRPGERAATDGTIRSGQTSLDLSAITGESLPVEAGPGSDVFAGAINGGGAIEVEVTALAADSSLARIVHIVEEAQERK
GAGQRLADRIARPLVPAIMALAAAIAAVGAVFGDPMLWLERALVVLVAASPCALAIAVPLTVVAAIGAASRHGALIKGGA
AVEELGRIKVVALDKTGTLTRNQPRVIDVITTDDFSDDDALRWAAALETRSEHPLAQAILTAAGDPPIASDVTAVPGHGL
HGELDGYRLRLGKPSWVTPGPLADDIERLQAAGATVVVLARDEQPVAAIAVRDELRPEAADTVRLLTRLGLTVAMLTGDN
ARTAEAVAAEAGITNVHSELLPEDKAALLRTIAQGRPIAMVGDGINDAPALATADIGIAMGAMGTDVAIETADVALMGED
LRHLPQVLAHSRRARGIMVQNIAFSLAIIAVLIPLAAFGVLGLATVVLIHETAEVLVILNAIRAARIAALPGVTTSSPRS
TTHAIDIGPAPTLDDPCCGPQRSTPPSATKLNSPLVAADVAPNDHGCDCCAPAGPPLADDPTASIRANHR
>Mature_709_residues
SDACCGPRDDAELDAGPEKLWQVRELQFAVLAAVLLSVGWIVGRFGGYEGVVEAVELAAVAAGAITFVPDAARNLRHGRI
GVGTLMTIAAIGAVALGQFAEAALLGILFSIAEGLEHYAVSRTRRGLRSLLSLVPPKASVLRHGTETTVAPGELVVGDVM
VIRPGERAATDGTIRSGQTSLDLSAITGESLPVEAGPGSDVFAGAINGGGAIEVEVTALAADSSLARIVHIVEEAQERKG
AGQRLADRIARPLVPAIMALAAAIAAVGAVFGDPMLWLERALVVLVAASPCALAIAVPLTVVAAIGAASRHGALIKGGAA
VEELGRIKVVALDKTGTLTRNQPRVIDVITTDDFSDDDALRWAAALETRSEHPLAQAILTAAGDPPIASDVTAVPGHGLH
GELDGYRLRLGKPSWVTPGPLADDIERLQAAGATVVVLARDEQPVAAIAVRDELRPEAADTVRLLTRLGLTVAMLTGDNA
RTAEAVAAEAGITNVHSELLPEDKAALLRTIAQGRPIAMVGDGINDAPALATADIGIAMGAMGTDVAIETADVALMGEDL
RHLPQVLAHSRRARGIMVQNIAFSLAIIAVLIPLAAFGVLGLATVVLIHETAEVLVILNAIRAARIAALPGVTTSSPRST
THAIDIGPAPTLDDPCCGPQRSTPPSATKLNSPLVAADVAPNDHGCDCCAPAGPPLADDPTASIRANHR

Specific function: Involved In Export Of Lead, Cadmium, Zinc And Mercury. [C]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=632, Percent_Identity=31.9620253164557, Blast_Score=265, Evalue=9e-71,
Organism=Homo sapiens, GI115529486, Length=657, Percent_Identity=30.1369863013699, Blast_Score=256, Evalue=5e-68,
Organism=Homo sapiens, GI55743073, Length=533, Percent_Identity=32.6454033771107, Blast_Score=235, Evalue=1e-61,
Organism=Homo sapiens, GI48762689, Length=284, Percent_Identity=25.7042253521127, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI48762691, Length=284, Percent_Identity=25.7042253521127, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI48762687, Length=284, Percent_Identity=25.7042253521127, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI48762685, Length=284, Percent_Identity=25.7042253521127, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI118498343, Length=247, Percent_Identity=28.7449392712551, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI22748667, Length=246, Percent_Identity=26.0162601626016, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1789879, Length=602, Percent_Identity=39.5348837209302, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI1786691, Length=546, Percent_Identity=37.3626373626374, Blast_Score=270, Evalue=3e-73,
Organism=Escherichia coli, GI1786914, Length=459, Percent_Identity=30.9368191721133, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI2367363, Length=235, Percent_Identity=28.936170212766, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17556548, Length=591, Percent_Identity=30.7952622673435, Blast_Score=224, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI71997262, Length=239, Percent_Identity=31.3807531380753, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71997275, Length=239, Percent_Identity=31.3807531380753, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71997269, Length=239, Percent_Identity=31.3807531380753, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17541776, Length=202, Percent_Identity=27.2277227722772, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17557486, Length=248, Percent_Identity=26.6129032258064, Blast_Score=79, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6320475, Length=605, Percent_Identity=29.5867768595041, Blast_Score=222, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6319772, Length=552, Percent_Identity=28.2608695652174, Blast_Score=197, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6325221, Length=565, Percent_Identity=25.6637168141593, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321430, Length=584, Percent_Identity=25.513698630137, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321432, Length=184, Percent_Identity=32.0652173913043, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6321271, Length=200, Percent_Identity=29.5, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI221329854, Length=412, Percent_Identity=31.7961165048544, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI161085803, Length=292, Percent_Identity=27.0547945205479, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24668696, Length=292, Percent_Identity=27.0547945205479, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281366617, Length=292, Percent_Identity=27.0547945205479, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24668704, Length=292, Percent_Identity=27.0547945205479, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24668708, Length=292, Percent_Identity=27.0547945205479, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006404
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: 3.6.3.3 [C]

Molecular weight: Translated: 72839; Mature: 72707

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00154 ATPASE_E1_E2 ; PS00214 FABP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDACCGPRDDAELDAGPEKLWQVRELQFAVLAAVLLSVGWIVGRFGGYEGVVEAVELAA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VAAGAITFVPDAARNLRHGRIGVGTLMTIAAIGAVALGQFAEAALLGILFSIAEGLEHYA
HHHCHHEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRTRRGLRSLLSLVPPKASVLRHGTETTVAPGELVVGDVMVIRPGERAATDGTIRSGQT
HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCEEECCEEEECCCCCCCCCCCCCCCCC
SLDLSAITGESLPVEAGPGSDVFAGAINGGGAIEVEVTALAADSSLARIVHIVEEAQERK
CEEEEEECCCCCCCCCCCCCCEEEEEECCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHC
GAGQRLADRIARPLVPAIMALAAAIAAVGAVFGDPMLWLERALVVLVAASPCALAIAVPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHH
TVVAAIGAASRHGALIKGGAAVEELGRIKVVALDKTGTLTRNQPRVIDVITTDDFSDDDA
HHHHHHCCCCCCCCEEECCHHHHHCCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCCHH
LRWAAALETRSEHPLAQAILTAAGDPPIASDVTAVPGHGLHGELDGYRLRLGKPSWVTPG
HHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCC
PLADDIERLQAAGATVVVLARDEQPVAAIAVRDELRPEAADTVRLLTRLGLTVAMLTGDN
CCHHHHHHHHHCCCEEEEEECCCCCEEEEEEHHHCCCCHHHHHHHHHHHCCEEEEEECCC
ARTAEAVAAEAGITNVHSELLPEDKAALLRTIAQGRPIAMVGDGINDAPALATADIGIAM
CCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCEEHHHHHHH
GAMGTDVAIETADVALMGEDLRHLPQVLAHSRRARGIMVQNIAFSLAIIAVLIPLAAFGV
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHH
LGLATVVLIHETAEVLVILNAIRAARIAALPGVTTSSPRSTTHAIDIGPAPTLDDPCCGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCC
QRSTPPSATKLNSPLVAADVAPNDHGCDCCAPAGPPLADDPTASIRANHR
CCCCCCCCHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDACCGPRDDAELDAGPEKLWQVRELQFAVLAAVLLSVGWIVGRFGGYEGVVEAVELAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VAAGAITFVPDAARNLRHGRIGVGTLMTIAAIGAVALGQFAEAALLGILFSIAEGLEHYA
HHHCHHEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRTRRGLRSLLSLVPPKASVLRHGTETTVAPGELVVGDVMVIRPGERAATDGTIRSGQT
HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCEEECCEEEECCCCCCCCCCCCCCCCC
SLDLSAITGESLPVEAGPGSDVFAGAINGGGAIEVEVTALAADSSLARIVHIVEEAQERK
CEEEEEECCCCCCCCCCCCCCEEEEEECCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHC
GAGQRLADRIARPLVPAIMALAAAIAAVGAVFGDPMLWLERALVVLVAASPCALAIAVPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHH
TVVAAIGAASRHGALIKGGAAVEELGRIKVVALDKTGTLTRNQPRVIDVITTDDFSDDDA
HHHHHHCCCCCCCCEEECCHHHHHCCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCCHH
LRWAAALETRSEHPLAQAILTAAGDPPIASDVTAVPGHGLHGELDGYRLRLGKPSWVTPG
HHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCC
PLADDIERLQAAGATVVVLARDEQPVAAIAVRDELRPEAADTVRLLTRLGLTVAMLTGDN
CCHHHHHHHHHCCCEEEEEECCCCCEEEEEEHHHCCCCHHHHHHHHHHHCCEEEEEECCC
ARTAEAVAAEAGITNVHSELLPEDKAALLRTIAQGRPIAMVGDGINDAPALATADIGIAM
CCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCEEHHHHHHH
GAMGTDVAIETADVALMGEDLRHLPQVLAHSRRARGIMVQNIAFSLAIIAVLIPLAAFGV
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHH
LGLATVVLIHETAEVLVILNAIRAARIAALPGVTTSSPRSTTHAIDIGPAPTLDDPCCGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCC
QRSTPPSATKLNSPLVAADVAPNDHGCDCCAPAGPPLADDPTASIRANHR
CCCCCCCCHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]