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The map label for this gene is cadC [H]

Identifier: 119855080

GI number: 119855080

Start: 203011

End: 203394

Strand: Direct

Name: cadC [H]

Synonym: Mkms_5692

Alternate gene names: 119855080

Gene position: 203011-203394 (Clockwise)

Preceding gene: 119855079

Following gene: 119855081

Centisome position: 67.2

GC content: 67.45

Gene sequence:

>384_bases
ATGACGGAGCCGGTGGACACTTGCGATCTCCTCTGTTTGGACCTGCCGCGCGCGGAGTCCATCCGGGCCACGGTTCCAGA
CCCCGCCACCATTCAAGCCGCCGCCGCGGCGGCGCGCGGCCTGAGCGATGCGACCCGGTTGTCCATTGCGGCCGCACTCG
CCGCCGGTGACGAGCTGTGCGTTTGCGACATGGCCTGGGTGGTCGGACTGCCGCAGGGCTTGGTCTCACACCACCTGCGC
CAACTCAAGAACGCGTCGCTGGTGTCCTCGCGGCGTCAGGGCAAGTTGGTGATGTACCAGCTGACCGAGCGTGGCCGCCA
GCTGACCGACTCGGTGCTCGCCAGTGCGGTCGCGCTTACGGGGAAGGAATCCGATTGTGTCTGA

Upstream 100 bases:

>100_bases
CGACGTGCGGTGGCACTGCAGATTCTCCGACTCGGCCCCGTGTTGATCAGGATTGCGCAAGCCCTTCCACGGACATATCA
ACGTACTTTAGTATGTGGAT

Downstream 100 bases:

>100_bases
TGCGTGCTGCGGGCCGCGCGACGACGCCGAACTCGACGCAGGTCCCGAGAAGCTTTGGCAAGTAAGAGAGTTGCAGTTCG
CGGTGCTCGCGGCGGTCCTG

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 126

Protein sequence:

>127_residues
MTEPVDTCDLLCLDLPRAESIRATVPDPATIQAAAAAARGLSDATRLSIAAALAAGDELCVCDMAWVVGLPQGLVSHHLR
QLKNASLVSSRRQGKLVMYQLTERGRQLTDSVLASAVALTGKESDCV

Sequences:

>Translated_127_residues
MTEPVDTCDLLCLDLPRAESIRATVPDPATIQAAAAAARGLSDATRLSIAAALAAGDELCVCDMAWVVGLPQGLVSHHLR
QLKNASLVSSRRQGKLVMYQLTERGRQLTDSVLASAVALTGKESDCV
>Mature_126_residues
TEPVDTCDLLCLDLPRAESIRATVPDPATIQAAAAAARGLSDATRLSIAAALAAGDELCVCDMAWVVGLPQGLVSHHLRQ
LKNASLVSSRRQGKLVMYQLTERGRQLTDSVLASAVALTGKESDCV

Specific function: Metal-binding repressor for the cad operon. Involved in resistance to heavy metals, such as cadmium, bismuth, zinc or lead. Metal binding causes the repressor to dissociate from the DNA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13359; Mature: 13227

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPVDTCDLLCLDLPRAESIRATVPDPATIQAAAAAARGLSDATRLSIAAALAAGDELC
CCCCCCCHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCH
VCDMAWVVGLPQGLVSHHLRQLKNASLVSSRRQGKLVMYQLTERGRQLTDSVLASAVALT
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHC
GKESDCV
CCCCCCC
>Mature Secondary Structure 
TEPVDTCDLLCLDLPRAESIRATVPDPATIQAAAAAARGLSDATRLSIAAALAAGDELC
CCCCCCHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCH
VCDMAWVVGLPQGLVSHHLRQLKNASLVSSRRQGKLVMYQLTERGRQLTDSVLASAVALT
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHC
GKESDCV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1321115 [H]