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The map label for this gene is cadA [H]

Identifier: 119855063

GI number: 119855063

Start: 185121

End: 187676

Strand: Direct

Name: cadA [H]

Synonym: Mkms_5674

Alternate gene names: 119855063

Gene position: 185121-187676 (Clockwise)

Preceding gene: 119855062

Following gene: 119855064

Centisome position: 61.28

GC content: 67.8

Gene sequence:

>2556_bases
ATGCGTATTATTGCATGTATGGCAGATCGCAACGGCGAGACGGTGAGCCCCGGCGCCGACGAAACGCCCACGAATAGGAC
CCTGGCTCTCGACCTGACAGACCTGCTTCCCGGTAGCGACGAGCGTTGTGCTGACCGCCTGACGCGCGGCCTGGTGGATG
ACGGGATCATCGAAGTGGCCCACGTCATCGATGGCGACACGACCAAACCCCGCCTGTGTGTGCACTACGACGCCGAGGCT
GCGTCCGCAACAGAAGTGCAGCGGCGGGCTCTGCAGGCGGCCGACACGATCACGTCGACGTACGGGCACCTTCGCTGGTT
GACTACAGGCACTCATGACGACGAGGCGATACGAACTGCGCTCGCCGACACGCTCTCGACGATGCCTGGCGTGGTCGCCG
CAGTAGCGACACCCGATTCGATCGAGCTGGAGTTCGAGCGGGCGACGGTGACGGCCCAAGAGCTTGTAGACGTCATTGCT
GCGCAGGTGGCGCCGTCGAGGAGTGCCGCCGCGGTTGAAGCCGCCGTCGCGCACGAGAGAGACGGCGCCGACCATCAACA
TGGTCACGGCGGGATCTTCGGCGAGCGCACCGAACTGGTCTTCGCGGGACTGGCGGGCTCGCTGCTGCTCACGGGCTGGT
TACTGGCTGCCTTCGCCGATACGCCGCGCTCGGCCGAGGTGGTGGTCTACGGCCTGGCGTTCTTCTTCGGCGCGTTCTTC
ACCGTGCAGGAAGCCTTTGCCAGTGTGCGGCAGGGCCGGTTTGAGATCGACTTCCTCATGCTCGTCTCTGCCGCGGGTGC
GGCGGCGCTCGGCGAAATCGCCGAAGGCGCGCTCCTGCTGTTCCTCTTCAGCGTCGGACACGCACTCGAGGGCTATGCGA
TGGGCCGGGCTCGCCGGGCGATCGAAGCGCTCGCCGAACTCGCCCCGAAGACGGCGCTGGTGCGGCGCGGCGGCACAGGC
GACACCGTCGAAGTATCCGTTGCGGACCTGCGCATTGGCGACATCGTCGTCGTGCGCCCCAACATGCGTCTGGCCGCAGA
CGGCTTCGTCGTGGCAGGCAGCAGCAGCATCGATCAAGCCCCGGTGACCGGGGAGAGCGTCCCCGTCGACAAGAGTCCGG
TCCCGGACGTGGCGGCAGCCGCCGCGTCACCCGAGCTCATCGACGCGGCATCGCGGGTGTTCGCCGGCACCATCAACGGT
GCCGGCGCCATCGAGGTTCAGGTGACCCGGCTCGCCGGTGACTCCACCCTGGCCCGCGTGGTGCGTCTGGTGGCCGAGGC
GCAAACCAAGACCACCTCCACGCAGCGCTTCACCGACCGGTTCCAGCGCGTTTTCGTGCCCGTGATCCTGGTCGGTGTGG
TCCTGCTGCTCTTCGCCGGGTTCGTGGTCGACGAGCCGTTTACTGACACGGTGTACCGGGCGCTTGCCGTTCTGGTGGCG
GCCAGCCCGTGTGCGCTGGCGATAGCCACGCCCAGCGCGGTGTTGTCGGCGGTGGCGAGGGCGGCGCGGGCCGGCATCCT
GATGAAGGGCGGTGCCGCATTGGAGGAACTTGGCCGGGTCGACGTGCTGGCCTTTGACAAGACCGGCACCCTCACCGAGG
GGCGGCCCAGGATCGCCGATGTCTGCGCCACAGCAGACAGCGACGACGCCGAACTGTTGAGGATCGCCGTGGCCGTGGAG
GAGCAAAGCGACCATCCGCTCGCCCGCGCTATCGTCCGCGATGGCCGCGAGCGCCTGGCCGGTGCGGTGACACCCCGCGC
GTCCGACGTCCGTGCGGTGATCGGCCGCGGCATCGTCGCGTCCGTCGATGGGATTGAGGTCTGGATCGGCAAGACGGAGT
TGTTCACCGACGCCGCTCAGCCCCCGCCGCTTGAGTTGGCGGCAGAGGTGGATCGACTCGAACAGGCGGGGCGCACAACG
ATGCTCGTCCGCGCGGGCGACCGATGGTTGGGCGCGATCGGATTGATGGACCTTCCTCGGCCGGAGGCGTCGGCGGTCGT
AGCACGTCTTGCCGCACTCGGCGTGACGAACACCGTGATGCTGTCGGGGGACAACCAGCGGGTGGCCGATGCCGTCGCCG
CCGAGGTCGGTGTCGCCGACGCTCGCGGCGACCTGATGCCCGAGGACAAGGTGGCTCAGATCGCCGCCCTCCGGGAACGC
GGCGGCCGCGTTGGGATGGTCGGTGACGGTGTCAACGATGCGCCCGCGATGGCTGGCGCGAATGTGGGTATTGCGATGGG
GGCGGCGGGCTCCGACGTGGCGTTGGAGACCGCTGACGTTGCGTTAATGGCCGACGACCTGCGCGCATTGCCGTTTGCGG
TGAGCCTGAGCCGCCGCTCCTCCCGCGTCATCAAGCAGAATCTGTGGGCCAGTCTCGGAATCGTCGCGGTCCTCATCCCG
GCGACGGTCTTTGGTCTGGGCATCGGTCCCGCCGTGCTCATTCACGAAGGCTCTACTCTTATCGTCGTCGCCAATGCGTT
GCGCCTCCTCGGGATGCCGATGCAGTCGGTGACCCCAGCAGCGCCGCGCGTTGAGCGTGCAGAAGAGACGCCATGA

Upstream 100 bases:

>100_bases
TGAATCTGTCGGCTCGAATCCGTGTCGTCGACGTCGGCGTGGTGACGCATCCCGCCGACGCGCGGGTTCGCAAACTAGGG
TTGACGGGTCATGTGCATAC

Downstream 100 bases:

>100_bases
CGATCGACCCGTTCAGCGCTGCAGATGAATTCGAGCATGCCGACGTCGACACTGTGGTCATCTTCGTCGACATCGCGGGG
TTCACGGCGTTCACCGAGGC

Product: heavy metal translocating P-type ATPase

Products: NA

Alternate protein names: Cadmium efflux ATPase [H]

Number of amino acids: Translated: 851; Mature: 851

Protein sequence:

>851_residues
MRIIACMADRNGETVSPGADETPTNRTLALDLTDLLPGSDERCADRLTRGLVDDGIIEVAHVIDGDTTKPRLCVHYDAEA
ASATEVQRRALQAADTITSTYGHLRWLTTGTHDDEAIRTALADTLSTMPGVVAAVATPDSIELEFERATVTAQELVDVIA
AQVAPSRSAAAVEAAVAHERDGADHQHGHGGIFGERTELVFAGLAGSLLLTGWLLAAFADTPRSAEVVVYGLAFFFGAFF
TVQEAFASVRQGRFEIDFLMLVSAAGAAALGEIAEGALLLFLFSVGHALEGYAMGRARRAIEALAELAPKTALVRRGGTG
DTVEVSVADLRIGDIVVVRPNMRLAADGFVVAGSSSIDQAPVTGESVPVDKSPVPDVAAAAASPELIDAASRVFAGTING
AGAIEVQVTRLAGDSTLARVVRLVAEAQTKTTSTQRFTDRFQRVFVPVILVGVVLLLFAGFVVDEPFTDTVYRALAVLVA
ASPCALAIATPSAVLSAVARAARAGILMKGGAALEELGRVDVLAFDKTGTLTEGRPRIADVCATADSDDAELLRIAVAVE
EQSDHPLARAIVRDGRERLAGAVTPRASDVRAVIGRGIVASVDGIEVWIGKTELFTDAAQPPPLELAAEVDRLEQAGRTT
MLVRAGDRWLGAIGLMDLPRPEASAVVARLAALGVTNTVMLSGDNQRVADAVAAEVGVADARGDLMPEDKVAQIAALRER
GGRVGMVGDGVNDAPAMAGANVGIAMGAAGSDVALETADVALMADDLRALPFAVSLSRRSSRVIKQNLWASLGIVAVLIP
ATVFGLGIGPAVLIHEGSTLIVVANALRLLGMPMQSVTPAAPRVERAEETP

Sequences:

>Translated_851_residues
MRIIACMADRNGETVSPGADETPTNRTLALDLTDLLPGSDERCADRLTRGLVDDGIIEVAHVIDGDTTKPRLCVHYDAEA
ASATEVQRRALQAADTITSTYGHLRWLTTGTHDDEAIRTALADTLSTMPGVVAAVATPDSIELEFERATVTAQELVDVIA
AQVAPSRSAAAVEAAVAHERDGADHQHGHGGIFGERTELVFAGLAGSLLLTGWLLAAFADTPRSAEVVVYGLAFFFGAFF
TVQEAFASVRQGRFEIDFLMLVSAAGAAALGEIAEGALLLFLFSVGHALEGYAMGRARRAIEALAELAPKTALVRRGGTG
DTVEVSVADLRIGDIVVVRPNMRLAADGFVVAGSSSIDQAPVTGESVPVDKSPVPDVAAAAASPELIDAASRVFAGTING
AGAIEVQVTRLAGDSTLARVVRLVAEAQTKTTSTQRFTDRFQRVFVPVILVGVVLLLFAGFVVDEPFTDTVYRALAVLVA
ASPCALAIATPSAVLSAVARAARAGILMKGGAALEELGRVDVLAFDKTGTLTEGRPRIADVCATADSDDAELLRIAVAVE
EQSDHPLARAIVRDGRERLAGAVTPRASDVRAVIGRGIVASVDGIEVWIGKTELFTDAAQPPPLELAAEVDRLEQAGRTT
MLVRAGDRWLGAIGLMDLPRPEASAVVARLAALGVTNTVMLSGDNQRVADAVAAEVGVADARGDLMPEDKVAQIAALRER
GGRVGMVGDGVNDAPAMAGANVGIAMGAAGSDVALETADVALMADDLRALPFAVSLSRRSSRVIKQNLWASLGIVAVLIP
ATVFGLGIGPAVLIHEGSTLIVVANALRLLGMPMQSVTPAAPRVERAEETP
>Mature_851_residues
MRIIACMADRNGETVSPGADETPTNRTLALDLTDLLPGSDERCADRLTRGLVDDGIIEVAHVIDGDTTKPRLCVHYDAEA
ASATEVQRRALQAADTITSTYGHLRWLTTGTHDDEAIRTALADTLSTMPGVVAAVATPDSIELEFERATVTAQELVDVIA
AQVAPSRSAAAVEAAVAHERDGADHQHGHGGIFGERTELVFAGLAGSLLLTGWLLAAFADTPRSAEVVVYGLAFFFGAFF
TVQEAFASVRQGRFEIDFLMLVSAAGAAALGEIAEGALLLFLFSVGHALEGYAMGRARRAIEALAELAPKTALVRRGGTG
DTVEVSVADLRIGDIVVVRPNMRLAADGFVVAGSSSIDQAPVTGESVPVDKSPVPDVAAAAASPELIDAASRVFAGTING
AGAIEVQVTRLAGDSTLARVVRLVAEAQTKTTSTQRFTDRFQRVFVPVILVGVVLLLFAGFVVDEPFTDTVYRALAVLVA
ASPCALAIATPSAVLSAVARAARAGILMKGGAALEELGRVDVLAFDKTGTLTEGRPRIADVCATADSDDAELLRIAVAVE
EQSDHPLARAIVRDGRERLAGAVTPRASDVRAVIGRGIVASVDGIEVWIGKTELFTDAAQPPPLELAAEVDRLEQAGRTT
MLVRAGDRWLGAIGLMDLPRPEASAVVARLAALGVTNTVMLSGDNQRVADAVAAEVGVADARGDLMPEDKVAQIAALRER
GGRVGMVGDGVNDAPAMAGANVGIAMGAAGSDVALETADVALMADDLRALPFAVSLSRRSSRVIKQNLWASLGIVAVLIP
ATVFGLGIGPAVLIHEGSTLIVVANALRLLGMPMQSVTPAAPRVERAEETP

Specific function: This electroneutral antiporter ejects one cadmium ion while accumulating two protons by an energy-dependent efflux mechanism [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HMA domain [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=669, Percent_Identity=31.2406576980568, Blast_Score=269, Evalue=1e-71,
Organism=Homo sapiens, GI115529486, Length=735, Percent_Identity=28.7074829931973, Blast_Score=262, Evalue=1e-69,
Organism=Homo sapiens, GI55743073, Length=512, Percent_Identity=32.2265625, Blast_Score=234, Evalue=3e-61,
Organism=Homo sapiens, GI118498343, Length=189, Percent_Identity=30.1587301587302, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI48762685, Length=153, Percent_Identity=33.9869281045752, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI48762689, Length=153, Percent_Identity=33.9869281045752, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI48762691, Length=153, Percent_Identity=33.9869281045752, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI48762687, Length=153, Percent_Identity=33.9869281045752, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI153946397, Length=259, Percent_Identity=26.6409266409266, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI21361181, Length=254, Percent_Identity=25.1968503937008, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI237681111, Length=254, Percent_Identity=25.1968503937008, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI237681109, Length=254, Percent_Identity=25.1968503937008, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI66932949, Length=210, Percent_Identity=25.7142857142857, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI213972621, Length=268, Percent_Identity=25.7462686567164, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI213972619, Length=268, Percent_Identity=25.7462686567164, Blast_Score=72, Evalue=3e-12,
Organism=Homo sapiens, GI13435129, Length=268, Percent_Identity=25.7462686567164, Blast_Score=72, Evalue=3e-12,
Organism=Homo sapiens, GI22748667, Length=254, Percent_Identity=25.5905511811024, Blast_Score=72, Evalue=3e-12,
Organism=Homo sapiens, GI28373113, Length=201, Percent_Identity=29.3532338308458, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI28373103, Length=201, Percent_Identity=29.3532338308458, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI28373109, Length=201, Percent_Identity=29.3532338308458, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI28373107, Length=201, Percent_Identity=29.3532338308458, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI4502271, Length=254, Percent_Identity=24.4094488188976, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI28373105, Length=201, Percent_Identity=29.3532338308458, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI28373115, Length=201, Percent_Identity=29.3532338308458, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI28373111, Length=201, Percent_Identity=29.3532338308458, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI51944966, Length=247, Percent_Identity=26.7206477732794, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1789879, Length=606, Percent_Identity=39.7689768976898, Blast_Score=358, Evalue=1e-99,
Organism=Escherichia coli, GI1786691, Length=573, Percent_Identity=34.0314136125654, Blast_Score=236, Evalue=7e-63,
Organism=Escherichia coli, GI1786914, Length=497, Percent_Identity=28.7726358148893, Blast_Score=127, Evalue=4e-30,
Organism=Escherichia coli, GI2367363, Length=643, Percent_Identity=23.0171073094868, Blast_Score=107, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17556548, Length=684, Percent_Identity=28.6549707602339, Blast_Score=225, Evalue=8e-59,
Organism=Caenorhabditis elegans, GI17559224, Length=297, Percent_Identity=25.9259259259259, Blast_Score=80, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71997262, Length=189, Percent_Identity=26.984126984127, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71997275, Length=189, Percent_Identity=26.984126984127, Blast_Score=77, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193203356, Length=243, Percent_Identity=25.9259259259259, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI193203354, Length=243, Percent_Identity=26.7489711934156, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71997269, Length=153, Percent_Identity=30.718954248366, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32566766, Length=173, Percent_Identity=28.3236994219653, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17557770, Length=173, Percent_Identity=28.3236994219653, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320475, Length=644, Percent_Identity=29.0372670807453, Blast_Score=242, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6319772, Length=594, Percent_Identity=26.0942760942761, Blast_Score=177, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6321271, Length=592, Percent_Identity=23.8175675675676, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6320243, Length=175, Percent_Identity=33.7142857142857, Blast_Score=84, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6320244, Length=175, Percent_Identity=33.7142857142857, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320245, Length=175, Percent_Identity=33.7142857142857, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321432, Length=95, Percent_Identity=41.0526315789474, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI221329854, Length=424, Percent_Identity=31.3679245283019, Blast_Score=157, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24668704, Length=149, Percent_Identity=34.2281879194631, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24668708, Length=149, Percent_Identity=34.2281879194631, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI161085803, Length=149, Percent_Identity=34.2281879194631, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281366617, Length=149, Percent_Identity=34.2281879194631, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24668696, Length=149, Percent_Identity=34.2281879194631, Blast_Score=74, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281362164, Length=253, Percent_Identity=25.6916996047431, Blast_Score=69, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45553435, Length=254, Percent_Identity=26.7716535433071, Blast_Score=69, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45553439, Length=254, Percent_Identity=26.7716535433071, Blast_Score=69, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45553441, Length=253, Percent_Identity=25.6916996047431, Blast_Score=69, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648580, Length=253, Percent_Identity=25.6916996047431, Blast_Score=69, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648578, Length=253, Percent_Identity=25.6916996047431, Blast_Score=69, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45553437, Length=253, Percent_Identity=25.6916996047431, Blast_Score=69, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648576, Length=253, Percent_Identity=25.6916996047431, Blast_Score=69, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648582, Length=253, Percent_Identity=25.6916996047431, Blast_Score=69, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281366676, Length=269, Percent_Identity=26.7657992565056, Blast_Score=67, Evalue=7e-11,
Organism=Drosophila melanogaster, GI17136664, Length=169, Percent_Identity=30.1775147928994, Blast_Score=66, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24762455, Length=169, Percent_Identity=30.1775147928994, Blast_Score=66, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24762453, Length=169, Percent_Identity=30.1775147928994, Blast_Score=66, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24762447, Length=169, Percent_Identity=30.1775147928994, Blast_Score=66, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24762457, Length=169, Percent_Identity=30.1775147928994, Blast_Score=66, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24762449, Length=169, Percent_Identity=30.1775147928994, Blast_Score=66, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24762445, Length=169, Percent_Identity=30.1775147928994, Blast_Score=66, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24762451, Length=169, Percent_Identity=30.1775147928994, Blast_Score=66, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR001366
- InterPro:   IPR006404
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: =3.6.3.3 [H]

Molecular weight: Translated: 88465; Mature: 88465

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIACMADRNGETVSPGADETPTNRTLALDLTDLLPGSDERCADRLTRGLVDDGIIEVA
CEEEEEEECCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCHHHHHHHHHCCCCCCHHHHH
HVIDGDTTKPRLCVHYDAEAASATEVQRRALQAADTITSTYGHLRWLTTGTHDDEAIRTA
HHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHH
LADTLSTMPGVVAAVATPDSIELEFERATVTAQELVDVIAAQVAPSRSAAAVEAAVAHER
HHHHHHHCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
DGADHQHGHGGIFGERTELVFAGLAGSLLLTGWLLAAFADTPRSAEVVVYGLAFFFGAFF
CCCCCCCCCCCCCCCCHHEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
TVQEAFASVRQGRFEIDFLMLVSAAGAAALGEIAEGALLLFLFSVGHALEGYAMGRARRA
HHHHHHHHHHCCCCEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEALAELAPKTALVRRGGTGDTVEVSVADLRIGDIVVVRPNMRLAADGFVVAGSSSIDQA
HHHHHHHCCHHHHHCCCCCCCEEEEEEEEEEECCEEEECCCCEEEECCEEEECCCCCCCC
PVTGESVPVDKSPVPDVAAAAASPELIDAASRVFAGTINGAGAIEVQVTRLAGDSTLARV
CCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHEECCCCCCEEEEEEEEECCCHHHHHH
VRLVAEAQTKTTSTQRFTDRFQRVFVPVILVGVVLLLFAGFVVDEPFTDTVYRALAVLVA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ASPCALAIATPSAVLSAVARAARAGILMKGGAALEELGRVDVLAFDKTGTLTEGRPRIAD
CCCCEEEEECHHHHHHHHHHHHHCCEEEECCHHHHHCCCEEEEEECCCCCCCCCCCHHHH
VCATADSDDAELLRIAVAVEEQSDHPLARAIVRDGRERLAGAVTPRASDVRAVIGRGIVA
HHHCCCCCCHHEEEEEEEEECCCCCHHHHHHHHCCHHHHHHCCCCCHHHHHHHHCCCCEE
SVDGIEVWIGKTELFTDAAQPPPLELAAEVDRLEQAGRTTMLVRAGDRWLGAIGLMDLPR
ECCCEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHEECCCCCCC
PEASAVVARLAALGVTNTVMLSGDNQRVADAVAAEVGVADARGDLMPEDKVAQIAALRER
CHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHC
GGRVGMVGDGVNDAPAMAGANVGIAMGAAGSDVALETADVALMADDLRALPFAVSLSRRS
CCEEEEECCCCCCCCCCCCCCCCEEECCCCCCCEEEHHHHEEEHHHHHHCCHHEEHHHHH
SRVIKQNLWASLGIVAVLIPATVFGLGIGPAVLIHEGSTLIVVANALRLLGMPMQSVTPA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEHHHHHHHHCCCHHHCCCC
APRVERAEETP
CCCCCCCCCCC
>Mature Secondary Structure
MRIIACMADRNGETVSPGADETPTNRTLALDLTDLLPGSDERCADRLTRGLVDDGIIEVA
CEEEEEEECCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCHHHHHHHHHCCCCCCHHHHH
HVIDGDTTKPRLCVHYDAEAASATEVQRRALQAADTITSTYGHLRWLTTGTHDDEAIRTA
HHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHH
LADTLSTMPGVVAAVATPDSIELEFERATVTAQELVDVIAAQVAPSRSAAAVEAAVAHER
HHHHHHHCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
DGADHQHGHGGIFGERTELVFAGLAGSLLLTGWLLAAFADTPRSAEVVVYGLAFFFGAFF
CCCCCCCCCCCCCCCCHHEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
TVQEAFASVRQGRFEIDFLMLVSAAGAAALGEIAEGALLLFLFSVGHALEGYAMGRARRA
HHHHHHHHHHCCCCEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEALAELAPKTALVRRGGTGDTVEVSVADLRIGDIVVVRPNMRLAADGFVVAGSSSIDQA
HHHHHHHCCHHHHHCCCCCCCEEEEEEEEEEECCEEEECCCCEEEECCEEEECCCCCCCC
PVTGESVPVDKSPVPDVAAAAASPELIDAASRVFAGTINGAGAIEVQVTRLAGDSTLARV
CCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHEECCCCCCEEEEEEEEECCCHHHHHH
VRLVAEAQTKTTSTQRFTDRFQRVFVPVILVGVVLLLFAGFVVDEPFTDTVYRALAVLVA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ASPCALAIATPSAVLSAVARAARAGILMKGGAALEELGRVDVLAFDKTGTLTEGRPRIAD
CCCCEEEEECHHHHHHHHHHHHHCCEEEECCHHHHHCCCEEEEEECCCCCCCCCCCHHHH
VCATADSDDAELLRIAVAVEEQSDHPLARAIVRDGRERLAGAVTPRASDVRAVIGRGIVA
HHHCCCCCCHHEEEEEEEEECCCCCHHHHHHHHCCHHHHHHCCCCCHHHHHHHHCCCCEE
SVDGIEVWIGKTELFTDAAQPPPLELAAEVDRLEQAGRTTMLVRAGDRWLGAIGLMDLPR
ECCCEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHEECCCCCCC
PEASAVVARLAALGVTNTVMLSGDNQRVADAVAAEVGVADARGDLMPEDKVAQIAALRER
CHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHC
GGRVGMVGDGVNDAPAMAGANVGIAMGAAGSDVALETADVALMADDLRALPFAVSLSRRS
CCEEEEECCCCCCCCCCCCCCCCEEECCCCCCCEEEHHHHEEEHHHHHHCCHHEEHHHHH
SRVIKQNLWASLGIVAVLIPATVFGLGIGPAVLIHEGSTLIVVANALRLLGMPMQSVTPA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEHHHHHHHHCCCHHHCCCC
APRVERAEETP
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1321115 [H]