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The map label for this gene is hupD [H]

Identifier: 119900081

GI number: 119900081

Start: 4153728

End: 4154408

Strand: Direct

Name: hupD [H]

Synonym: azo3792

Alternate gene names: 119900081

Gene position: 4153728-4154408 (Clockwise)

Preceding gene: 119900079

Following gene: 119900082

Centisome position: 94.92

GC content: 70.04

Gene sequence:

>681_bases
ATGGGCGCACAGGCTGGCACGCTCCCTGCTGCTGTTACGCGTCCCGTAACACCTGATCCCACCATGACTGCGCCCTCCCC
TGACTCCGCCCTGATCCTTGGCATCGGCAACCTGCTGTGGGCCGACGAAGGTTTCGGCGTGCGCTGCGTGGAAGCTTTCA
ACGCCGCATGGCAGGCGCCCGACAGCGTCACCGTGATGGACGGCGGCACCCAGGGCCTCTACCTGCTGCCCTACGTCACC
GCCGCGCGCCGGCTGATCGTGTTCGATGCGGTCGATTACGGTCTGGAACCCGGCACGCTGCGGCTGGTGGAAGACGACGA
GGTGCCGCGCTTCATGGGTGCCAAGAAGATGAGCCTGCACCAGACCGGCTTCCAGGAAGTGATCGCCTCGGCCGCGCTGC
TCGCCCAGTGCCCGCAGTCGATGCTGCTGATCGGCGTGCAGCCGGTGGAACTGGAAGACTTCGGCGGCAGCCTGCGGCCC
GCGGTGCGCGCCCGCGTGGACGAAGCGGTGGCGATTGCCGCGGCCCGGCTGCGCGAGTGGGGCTTCCCGCTGCAGGCACG
CCAGGACGAGGCCGCGCCGCTCGCCGACGCCGCGCTGCAGATGCAGCGCTACGAGGCCGGCCGCCCGCCCGAGGACCTCG
CCTGCCGCATTGGCGACATCCGCTTCATGCCGGAGCGCTGA

Upstream 100 bases:

>100_bases
GCATCCAATTCCGCCATGCCTCACCCAGCGCTATTGCTTTCGGCTAGGGGGCGGGAGGCCCGGATCGCGTGCCGCGCGCG
GCCTGCGGGGGCACGCCGCG

Downstream 100 bases:

>100_bases
GATGTGCGTCGGCATCCCCGTGCAGGTGCTGCGCAGCGAGGAAACGCGCGCGCTGTGCCGTGACCGCGACGGCAGCGACG
TGTGGGTGGATCTGCTGCTG

Product: hydrogenase expression/formation protein hupD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MGAQAGTLPAAVTRPVTPDPTMTAPSPDSALILGIGNLLWADEGFGVRCVEAFNAAWQAPDSVTVMDGGTQGLYLLPYVT
AARRLIVFDAVDYGLEPGTLRLVEDDEVPRFMGAKKMSLHQTGFQEVIASAALLAQCPQSMLLIGVQPVELEDFGGSLRP
AVRARVDEAVAIAAARLREWGFPLQARQDEAAPLADAALQMQRYEAGRPPEDLACRIGDIRFMPER

Sequences:

>Translated_226_residues
MGAQAGTLPAAVTRPVTPDPTMTAPSPDSALILGIGNLLWADEGFGVRCVEAFNAAWQAPDSVTVMDGGTQGLYLLPYVT
AARRLIVFDAVDYGLEPGTLRLVEDDEVPRFMGAKKMSLHQTGFQEVIASAALLAQCPQSMLLIGVQPVELEDFGGSLRP
AVRARVDEAVAIAAARLREWGFPLQARQDEAAPLADAALQMQRYEAGRPPEDLACRIGDIRFMPER
>Mature_225_residues
GAQAGTLPAAVTRPVTPDPTMTAPSPDSALILGIGNLLWADEGFGVRCVEAFNAAWQAPDSVTVMDGGTQGLYLLPYVTA
ARRLIVFDAVDYGLEPGTLRLVEDDEVPRFMGAKKMSLHQTGFQEVIASAALLAQCPQSMLLIGVQPVELEDFGGSLRPA
VRARVDEAVAIAAARLREWGFPLQARQDEAAPLADAALQMQRYEAGRPPEDLACRIGDIRFMPER

Specific function: Not known. Could be involved in the processing of hydrogenase [H]

COG id: COG0680

COG function: function code C; Ni,Fe-hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A31 family [H]

Homologues:

Organism=Escherichia coli, GI1787209, Length=183, Percent_Identity=45.9016393442623, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1789367, Length=163, Percent_Identity=38.6503067484663, Blast_Score=100, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004419
- InterPro:   IPR000671 [H]

Pfam domain/function: PF01750 HycI [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 24290; Mature: 24159

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAQAGTLPAAVTRPVTPDPTMTAPSPDSALILGIGNLLWADEGFGVRCVEAFNAAWQAP
CCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEECCCEEECCCCCCCHHHHHHHHHHCCC
DSVTVMDGGTQGLYLLPYVTAARRLIVFDAVDYGLEPGTLRLVEDDEVPRFMGAKKMSLH
CCEEEEECCCCCEEEHHHHHHHCEEEEEEHHHCCCCCCEEEEEECCCCCHHHCCCHHHHH
QTGFQEVIASAALLAQCPQSMLLIGVQPVELEDFGGSLRPAVRARVDEAVAIAAARLREW
HHHHHHHHHHHHHHHHCCHHHEEECCCCEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHC
GFPLQARQDEAAPLADAALQMQRYEAGRPPEDLACRIGDIRFMPER
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHEEECCEEECCCC
>Mature Secondary Structure 
GAQAGTLPAAVTRPVTPDPTMTAPSPDSALILGIGNLLWADEGFGVRCVEAFNAAWQAP
CCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEECCCEEECCCCCCCHHHHHHHHHHCCC
DSVTVMDGGTQGLYLLPYVTAARRLIVFDAVDYGLEPGTLRLVEDDEVPRFMGAKKMSLH
CCEEEEECCCCCEEEHHHHHHHCEEEEEEHHHCCCCCCEEEEEECCCCCHHHCCCHHHHH
QTGFQEVIASAALLAQCPQSMLLIGVQPVELEDFGGSLRPAVRARVDEAVAIAAARLREW
HHHHHHHHHHHHHHHHCCHHHEEECCCCEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHC
GFPLQARQDEAAPLADAALQMQRYEAGRPPEDLACRIGDIRFMPER
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHEEECCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Ni [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624446 [H]