Click here to switch to the map view.

The map label for this gene is gpwA [H]

Identifier: 119900079

GI number: 119900079

Start: 4151089

End: 4151679

Strand: Direct

Name: gpwA [H]

Synonym: azo3790

Alternate gene names: 119900079

Gene position: 4151089-4151679 (Clockwise)

Preceding gene: 119900078

Following gene: 119900081

Centisome position: 94.86

GC content: 68.7

Gene sequence:

>591_bases
ATGCGCACTACCGCCCTTGCCCTGACCTTGCTCGCCCTCGCCACCGCGGCCGTTGTGTACGCCGCCAGCGAGGCGCCCGT
ACCGGCCGCGACGCAAGCCGCCGCACCTGCCAGCCCGCTGCTCGACCACAGCTTCCGCCGCCTGCACGGGGCCGAAACGC
TCAACCTGCGCGAACGCTATGCCGGCCAACCGCTACTCATCGTCAACACCGCCAGCCATTGCGGCTACACCGGCCAGTTC
AAGGAACTGGAAGCCATCCACCAGCGCTACCGCGCGCAGGGGCTGAAGGTGCTCGGCTTCTCGTCGGACGACTTCAACCA
GGAGGCCGACAACGAAGCCAAGGCCGCCAACGTCTGCTTCGTGAACTTCGGCGTCACCTTCGACATGTTCGCGCCCATCC
ACGTGCGCGGCGGCGACGCGCACCCGCTGTTCCGCGAACTCGCGCGCCAGTCGCAGGCGCCGCGCTGGAATTTCCACAAG
TACGTGGTCGACCGCCAGGGCAAGGTGGTGGCCAGCTTCGAGAGCGCGGTCAAGCCGGACGCCCCCGAAGTGCTCGCCGC
GCTCGAACGCGCGATTGCGGGCGCTCGCTGA

Upstream 100 bases:

>100_bases
GATGCGCAGCGCCGGGTGAAGCGCGCCGCACGAACTTCCGCCACGCCCCGCCAGTCTCCGTCACATACCGCCGCCCCTGC
GGCGGTGCCGGAGAACCGCA

Downstream 100 bases:

>100_bases
GCGCCGGCTTCGCCACCGTTCAGGCCTCGGCTGGCGTCAGCGCGCGGAACATCGCACAGCGGTCGAAGGCCGCCATGTCG
GCCGGCACCGCCTTGCGGCT

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MRTTALALTLLALATAAVVYAASEAPVPAATQAAAPASPLLDHSFRRLHGAETLNLRERYAGQPLLIVNTASHCGYTGQF
KELEAIHQRYRAQGLKVLGFSSDDFNQEADNEAKAANVCFVNFGVTFDMFAPIHVRGGDAHPLFRELARQSQAPRWNFHK
YVVDRQGKVVASFESAVKPDAPEVLAALERAIAGAR

Sequences:

>Translated_196_residues
MRTTALALTLLALATAAVVYAASEAPVPAATQAAAPASPLLDHSFRRLHGAETLNLRERYAGQPLLIVNTASHCGYTGQF
KELEAIHQRYRAQGLKVLGFSSDDFNQEADNEAKAANVCFVNFGVTFDMFAPIHVRGGDAHPLFRELARQSQAPRWNFHK
YVVDRQGKVVASFESAVKPDAPEVLAALERAIAGAR
>Mature_196_residues
MRTTALALTLLALATAAVVYAASEAPVPAATQAAAPASPLLDHSFRRLHGAETLNLRERYAGQPLLIVNTASHCGYTGQF
KELEAIHQRYRAQGLKVLGFSSDDFNQEADNEAKAANVCFVNFGVTFDMFAPIHVRGGDAHPLFRELARQSQAPRWNFHK
YVVDRQGKVVASFESAVKPDAPEVLAALERAIAGAR

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=144, Percent_Identity=34.7222222222222, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI75709200, Length=183, Percent_Identity=29.5081967213115, Blast_Score=78, Evalue=4e-15,
Organism=Homo sapiens, GI192455698, Length=143, Percent_Identity=32.8671328671329, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI90903240, Length=134, Percent_Identity=31.3432835820896, Blast_Score=74, Evalue=6e-14,
Organism=Homo sapiens, GI90903238, Length=165, Percent_Identity=29.6969696969697, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1788003, Length=162, Percent_Identity=34.5679012345679, Blast_Score=103, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI71993584, Length=144, Percent_Identity=36.1111111111111, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193210707, Length=139, Percent_Identity=35.9712230215827, Blast_Score=81, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17535473, Length=131, Percent_Identity=35.1145038167939, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17506887, Length=153, Percent_Identity=30.718954248366, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6322228, Length=131, Percent_Identity=38.1679389312977, Blast_Score=111, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6319721, Length=131, Percent_Identity=37.4045801526718, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322826, Length=122, Percent_Identity=36.8852459016393, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI85726443, Length=128, Percent_Identity=34.375, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24656767, Length=186, Percent_Identity=27.9569892473118, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24656772, Length=157, Percent_Identity=29.2993630573248, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24656777, Length=157, Percent_Identity=29.2993630573248, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 21257; Mature: 21257

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTTALALTLLALATAAVVYAASEAPVPAATQAAAPASPLLDHSFRRLHGAETLNLRERY
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCHHHHHHHHHHCCCCCCCHHHHH
AGQPLLIVNTASHCGYTGQFKELEAIHQRYRAQGLKVLGFSSDDFNQEADNEAKAANVCF
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHEEEE
VNFGVTFDMFAPIHVRGGDAHPLFRELARQSQAPRWNFHKYVVDRQGKVVASFESAVKPD
EECCCEEEECCEEEEECCCCCHHHHHHHHHHCCCCCCHHHHEECCCCCEEEHHHHHCCCC
APEVLAALERAIAGAR
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRTTALALTLLALATAAVVYAASEAPVPAATQAAAPASPLLDHSFRRLHGAETLNLRERY
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCHHHHHHHHHHCCCCCCCHHHHH
AGQPLLIVNTASHCGYTGQFKELEAIHQRYRAQGLKVLGFSSDDFNQEADNEAKAANVCF
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHEEEE
VNFGVTFDMFAPIHVRGGDAHPLFRELARQSQAPRWNFHKYVVDRQGKVVASFESAVKPD
EECCCEEEECCEEEEECCCCCHHHHHHHHHHCCCCCCHHHHEECCCCCEEEHHHHHCCCC
APEVLAALERAIAGAR
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA