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The map label for this gene is ptsL [C]

Identifier: 119900069

GI number: 119900069

Start: 4142403

End: 4142786

Strand: Direct

Name: ptsL [C]

Synonym: azo3780

Alternate gene names: 119900069

Gene position: 4142403-4142786 (Clockwise)

Preceding gene: 119900068

Following gene: 119900070

Centisome position: 94.66

GC content: 63.8

Gene sequence:

>384_bases
ATGATCGGCATATTCCTCATCACGCACGGCACACTGGGCGAGGCCCTCATCCAGTGTGCGTGCCACGTGCTCAATAAAAG
ACCGGCGCAGATCATGCAGCTGGGCGTCACCGCGCAGGACGATCCGCTCGACCTGCTTCCGGTGGCGCGCCGCGTGCTGG
CGTTGACGGATTCGGGCGAGGGCGTCGTGGTGCTCACGGACATCTTCGGAGCCACCCCGTCCAACGTCGCCGCCAAGCTG
ATCGAGCCCGGCAGGGTCGAAGTCATCGCAGGGGTCAATCTCCCGATGTTGCTGCGGGTGCTGACCTACCGCGAGAAGGA
CATGAACACGCTCGTCCAGCGCGCGGTATCGGGTGGCTGCGACGGGGTCATCCACATCAAATAA

Upstream 100 bases:

>100_bases
TCGCGGGCCGTTCATCGGCCCCATACCCCGCAAACCCCGCCCCCGCGCTGAAGCAGCGGCGCTGCATCGGCTACAATCGG
CCGAAAGCACGGGGCAGGGC

Downstream 100 bases:

>100_bases
GAGTTACGGCAATGCCAAGAGCGGAAGCGCAAATCGTCAACAAGCTGGGCCTGCACGCGCGCGCATCGGCCAAGCTCACC
CAGCTCGCCAGCAGCTTTCC

Product: putative IIA component of sugar transport PTS system

Products: protein histidine; sugar phosphate

Alternate protein names: PTS System IIA Component; PTS System Fructose IIA Component; IIA Component Of Sugar Transport PTS System; PTS System Fructose-Specific IIA Component; Pts System Fructose Subfamily IIa Component; Fructose-Specific IIA Component; PTS System Transporter Subunit IIA; PTS System Fructose Subfamily Transporter Subunit IIA; Protein-N P-Phosphohistidine-Sugar Phosphotransferase; PTS Mannose-Specific IIA Component; Pts System Mannose-Specific Eiiab Component; Sugar Transport PTS System IIA Component; PTS System Fructose IIA Component Family Protein; PTS System Fructose-Specific Transporter Subunit IIA; Pts System Mannose/Fructose/Sorbose Family IIa Component; PTS System Fructose Subfamily Transprotein Subunit IIA; Pts System Fructose IIA Component; PTS System Mannose/Fructose-Specific Component IIA; IIa Component Of Sugar Transport PTS System; PTS System IIAB Component; Pts System IIa Component; PTS System Mannose-Type Transporter Subunit IIA; Pentitol Phosphotransferase IIA Component; PTS System Component IIA; Phosphotransferase System IIA Component; Phosphotransferase Mannose/Fructose-Specific Component IIA; PTS System Mannose/Fructose-Specific IIA Component; PTS System IIa Component; PTS System IIA Component Domain Protein; Phosphotransferase System Fructose-Specific IIA

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MIGIFLITHGTLGEALIQCACHVLNKRPAQIMQLGVTAQDDPLDLLPVARRVLALTDSGEGVVVLTDIFGATPSNVAAKL
IEPGRVEVIAGVNLPMLLRVLTYREKDMNTLVQRAVSGGCDGVIHIK

Sequences:

>Translated_127_residues
MIGIFLITHGTLGEALIQCACHVLNKRPAQIMQLGVTAQDDPLDLLPVARRVLALTDSGEGVVVLTDIFGATPSNVAAKL
IEPGRVEVIAGVNLPMLLRVLTYREKDMNTLVQRAVSGGCDGVIHIK
>Mature_127_residues
MIGIFLITHGTLGEALIQCACHVLNKRPAQIMQLGVTAQDDPLDLLPVARRVLALTDSGEGVVVLTDIFGATPSNVAAKL
IEPGRVEVIAGVNLPMLLRVLTYREKDMNTLVQRAVSGGCDGVIHIK

Specific function: This Is A Component Of The Phosphoenolpyruvate-Dependent Sugar Phosphotransferase System (Pts), A Major Carbohydrate Active -Transport System. The IIcd Domains Contain The Sugar Binding Site And The Transmembrane Channel; The IIa Domain Contains The Prim

COG id: COG2893

COG function: function code G; Phosphotransferase system, mannose/fructose-specific component IIA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788120, Length=129, Percent_Identity=32.5581395348837, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.1.69

Molecular weight: Translated: 13537; Mature: 13537

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS51096 PTS_EIIA_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGIFLITHGTLGEALIQCACHVLNKRPAQIMQLGVTAQDDPLDLLPVARRVLALTDSGE
CEEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHEEECCCCC
GVVVLTDIFGATPSNVAAKLIEPGRVEVIAGVNLPMLLRVLTYREKDMNTLVQRAVSGGC
CEEEEEECCCCCCCHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCCC
DGVIHIK
CEEEEEC
>Mature Secondary Structure
MIGIFLITHGTLGEALIQCACHVLNKRPAQIMQLGVTAQDDPLDLLPVARRVLALTDSGE
CEEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHEEECCCCC
GVVVLTDIFGATPSNVAAKLIEPGRVEVIAGVNLPMLLRVLTYREKDMNTLVQRAVSGGC
CEEEEEECCCCCCCHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCCC
DGVIHIK
CEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA