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The map label for this gene is prpC [H]

Identifier: 119897293

GI number: 119897293

Start: 1076945

End: 1077721

Strand: Direct

Name: prpC [H]

Synonym: azo1002

Alternate gene names: 119897293

Gene position: 1076945-1077721 (Clockwise)

Preceding gene: 119897292

Following gene: 119897294

Centisome position: 24.61

GC content: 66.28

Gene sequence:

>777_bases
ATGCCGCTGATTGCCGAAACCTGCGTCGCCCGCCACACCGGGGACAGGAAGGAGCAGCAGGACCGCGTCGCCCTGTTTGC
CCATCCCACCGAAACCGGGACCCTGCTGGCCGTGCTCGCCGACGGCATGGGCGGCCATTCCGGCGGGGCAATGGCGGCCG
AGCAGGTCACGATCAAGGCCAAGCAGAACTTCGAGGCTTTTCAGCCCGCGCATGAAACCGGCCGCCACTTGCTCCAGAGC
ATCGTCGATGAGGCGCATGTCGTCATCAAGCTGACCCGCTTCACCAGCGAGCAGGATCCGCACAGCACCGCGGTGGTCTT
CCTGATGCAGCCGGGTAAGGCGGCGTGGGCTCACTGCGGCGATTCGCGCCTGTACCACTTCCGCGGACGCGAACCCTGCT
TTCGCACGCAGGATCACTCGCTGGTGGGCGAGATGCTGCGCAAGGGCCGGCTCGACGAAGCCGGCGCGCTCAATCACCCG
CAACGCAACGTGCTGCTGTCCTGCCTGGGCAGCGAGCGCGAACCGCGTGTCGAGTACGGGGAGACGGACACGCTGATGGC
AGGCGACAGCTTCCTGCTGTGTTCCGACGGGCTGTGGTCCTATTTTTCCGACGACGAACTCGGCCTGGTGGTGGACAACC
ACCGCCCGCGCGAAGCCGCGCAACTGCTGATCGACCTTGCGCGCAGCCGCGCCGGCGGTTATGGCGACAATATTTCGCTC
GCGCTGATCAAGCTCTCCGATCCCAAGTCCAGCCCCCGCCCCGCGTTCATCGGCTGA

Upstream 100 bases:

>100_bases
CACAAACGGCATCCGGCGGCGGCTTTTCCGTGACCGGCGGCGGGGCGGGAGGGTGGGGTCATTGTTATGATGCGACTCAT
AACCAATGATCTAGCCCTCC

Downstream 100 bases:

>100_bases
GCCCGGCCGGCGCGGAATCAGGGAAATCCCCCATCCGTCTCATGGTTGTACGCAACCGCGTTCCCGGTAATATCCGGCGC
AATGCGCGCCGCATCGTCGG

Product: putative phosphoprotein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MPLIAETCVARHTGDRKEQQDRVALFAHPTETGTLLAVLADGMGGHSGGAMAAEQVTIKAKQNFEAFQPAHETGRHLLQS
IVDEAHVVIKLTRFTSEQDPHSTAVVFLMQPGKAAWAHCGDSRLYHFRGREPCFRTQDHSLVGEMLRKGRLDEAGALNHP
QRNVLLSCLGSEREPRVEYGETDTLMAGDSFLLCSDGLWSYFSDDELGLVVDNHRPREAAQLLIDLARSRAGGYGDNISL
ALIKLSDPKSSPRPAFIG

Sequences:

>Translated_258_residues
MPLIAETCVARHTGDRKEQQDRVALFAHPTETGTLLAVLADGMGGHSGGAMAAEQVTIKAKQNFEAFQPAHETGRHLLQS
IVDEAHVVIKLTRFTSEQDPHSTAVVFLMQPGKAAWAHCGDSRLYHFRGREPCFRTQDHSLVGEMLRKGRLDEAGALNHP
QRNVLLSCLGSEREPRVEYGETDTLMAGDSFLLCSDGLWSYFSDDELGLVVDNHRPREAAQLLIDLARSRAGGYGDNISL
ALIKLSDPKSSPRPAFIG
>Mature_257_residues
PLIAETCVARHTGDRKEQQDRVALFAHPTETGTLLAVLADGMGGHSGGAMAAEQVTIKAKQNFEAFQPAHETGRHLLQSI
VDEAHVVIKLTRFTSEQDPHSTAVVFLMQPGKAAWAHCGDSRLYHFRGREPCFRTQDHSLVGEMLRKGRLDEAGALNHPQ
RNVLLSCLGSEREPRVEYGETDTLMAGDSFLLCSDGLWSYFSDDELGLVVDNHRPREAAQLLIDLARSRAGGYGDNISLA
LIKLSDPKSSPRPAFIG

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 28283; Mature: 28152

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLIAETCVARHTGDRKEQQDRVALFAHPTETGTLLAVLADGMGGHSGGAMAAEQVTIKA
CCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCEEHEEEEEE
KQNFEAFQPAHETGRHLLQSIVDEAHVVIKLTRFTSEQDPHSTAVVFLMQPGKAAWAHCG
CCCCHHHCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCEEEEEEECCCCHHHHCCC
DSRLYHFRGREPCFRTQDHSLVGEMLRKGRLDEAGALNHPQRNVLLSCLGSEREPRVEYG
CCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
ETDTLMAGDSFLLCSDGLWSYFSDDELGLVVDNHRPREAAQLLIDLARSRAGGYGDNISL
CCCEEEECCCEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEE
ALIKLSDPKSSPRPAFIG
EEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
PLIAETCVARHTGDRKEQQDRVALFAHPTETGTLLAVLADGMGGHSGGAMAAEQVTIKA
CCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCEEHEEEEEE
KQNFEAFQPAHETGRHLLQSIVDEAHVVIKLTRFTSEQDPHSTAVVFLMQPGKAAWAHCG
CCCCHHHCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCEEEEEEECCCCHHHHCCC
DSRLYHFRGREPCFRTQDHSLVGEMLRKGRLDEAGALNHPQRNVLLSCLGSEREPRVEYG
CCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
ETDTLMAGDSFLLCSDGLWSYFSDDELGLVVDNHRPREAAQLLIDLARSRAGGYGDNISL
CCCEEEECCCEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEE
ALIKLSDPKSSPRPAFIG
EEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]