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The map label for this gene is prmA

Identifier: 119776356

GI number: 119776356

Start: 3817648

End: 3818535

Strand: Direct

Name: prmA

Synonym: Sama_3224

Alternate gene names: 119776356

Gene position: 3817648-3818535 (Clockwise)

Preceding gene: 119776355

Following gene: 119776357

Centisome position: 88.66

GC content: 57.77

Gene sequence:

>888_bases
ATGCCCTGGATCCAATTGCGCCTGCATTCAAGCAGCGAACACGCCGATGCCATCAGCGATCTGTTGATGGACGAAGGCTC
TGTCTCCATCACCTTTGAAGATGGTAAAGACCAACCCATTTTCGAACCCAAGCTGGGTGAAACTCCGCTGTGGAACGATA
CCGTGGTGGTGGCCCTGTTCGATGCCGACTTCGATTTGGCCCCCGTGGTAGACATGCTCAAGTCCCTGCCTTTCCTTGGC
AGCGAGCTCAAGTACAAGATTGAACAAATCGAAGACAAAGACTGGGTGCGTGAATGGATGGACAGCTATCACCCCATCCA
GTTCGGCAAGCGTCTGTGGATTTGCCCAAGCTGGCGTGAAGTGCCGGACCCAGAGGCCGTTAACGTGATCCTCGATCCGG
GCCTGGCCTTTGGCACCGGTACCCACCCCACCACGGCCCTGTGCCTTGAGTGGCTCGACAGCCTGGATTTGGCCGGCAAA
GACATTATCGACTTTGGCTGCGGCTCAGGCATCCTCGCCGTGGCCGCCCTTAAGCTGGGCGCTGCCAAAGCGACCGGTAT
CGACATCGACTATCAGGCCATCGACGCCTCCCGCGACAACGCCCAGCGTAATCAGGTAGAAGACCGTCTCGCCCTCTATC
TGCCCGAAGACCAACCCGCTGGCCTCAAGGCCGAAGTGTTGGTCGCCAATATTCTGGCTGGCCCACTGCGCGAACTGGCG
CCACTTATTCAGGCGCTGGTTCAGCCCGGTGGCAAGTTAGCCCTCTCGGGTTTGCTCAAAGAACAGGCCGCAGAAATCAG
TGAATGTTACGCCCAGTGGTTTGACATGGACCAACCTGCCCACAAAGACGACTGGAGCCGCTTGACAGGGGTACGCAAAT
CGCTGTAA

Upstream 100 bases:

>100_bases
GTGAGGATAAGGTGCTACATGCCCTTATCGTCACCCTTGATGCCAGCCAGGCGCTTGTGGGGTAGAATAGGGCTTTTCCT
ATTCAGCCACAGGATATTCC

Downstream 100 bases:

>100_bases
AAGGCGCGCCAACCCGCATGGGGGCGGGAAACCCCGCCCCGTAAATGTCAAGCAAAAAAGTTGTGCCCAGGTCATTTATT
GACCTTTTTTTCCCTCAAAA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MPWIQLRLHSSSEHADAISDLLMDEGSVSITFEDGKDQPIFEPKLGETPLWNDTVVVALFDADFDLAPVVDMLKSLPFLG
SELKYKIEQIEDKDWVREWMDSYHPIQFGKRLWICPSWREVPDPEAVNVILDPGLAFGTGTHPTTALCLEWLDSLDLAGK
DIIDFGCGSGILAVAALKLGAAKATGIDIDYQAIDASRDNAQRNQVEDRLALYLPEDQPAGLKAEVLVANILAGPLRELA
PLIQALVQPGGKLALSGLLKEQAAEISECYAQWFDMDQPAHKDDWSRLTGVRKSL

Sequences:

>Translated_295_residues
MPWIQLRLHSSSEHADAISDLLMDEGSVSITFEDGKDQPIFEPKLGETPLWNDTVVVALFDADFDLAPVVDMLKSLPFLG
SELKYKIEQIEDKDWVREWMDSYHPIQFGKRLWICPSWREVPDPEAVNVILDPGLAFGTGTHPTTALCLEWLDSLDLAGK
DIIDFGCGSGILAVAALKLGAAKATGIDIDYQAIDASRDNAQRNQVEDRLALYLPEDQPAGLKAEVLVANILAGPLRELA
PLIQALVQPGGKLALSGLLKEQAAEISECYAQWFDMDQPAHKDDWSRLTGVRKSL
>Mature_294_residues
PWIQLRLHSSSEHADAISDLLMDEGSVSITFEDGKDQPIFEPKLGETPLWNDTVVVALFDADFDLAPVVDMLKSLPFLGS
ELKYKIEQIEDKDWVREWMDSYHPIQFGKRLWICPSWREVPDPEAVNVILDPGLAFGTGTHPTTALCLEWLDSLDLAGKD
IIDFGCGSGILAVAALKLGAAKATGIDIDYQAIDASRDNAQRNQVEDRLALYLPEDQPAGLKAEVLVANILAGPLRELAP
LIQALVQPGGKLALSGLLKEQAAEISECYAQWFDMDQPAHKDDWSRLTGVRKSL

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=293, Percent_Identity=65.1877133105802, Blast_Score=360, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_SHEAM (A1SAM0)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_929096.1
- ProteinModelPortal:   A1SAM0
- SMR:   A1SAM0
- STRING:   A1SAM0
- GeneID:   4605471
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_3224
- NMPDR:   fig|326297.7.peg.3036
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   EREEWCR
- PhylomeDB:   A1SAM0
- ProtClustDB:   PRK00517
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32548; Mature: 32417

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWIQLRLHSSSEHADAISDLLMDEGSVSITFEDGKDQPIFEPKLGETPLWNDTVVVALF
CCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEE
DADFDLAPVVDMLKSLPFLGSELKYKIEQIEDKDWVREWMDSYHPIQFGKRLWICPSWRE
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHCCEEEECCCCCC
VPDPEAVNVILDPGLAFGTGTHPTTALCLEWLDSLDLAGKDIIDFGCGSGILAVAALKLG
CCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHC
AAKATGIDIDYQAIDASRDNAQRNQVEDRLALYLPEDQPAGLKAEVLVANILAGPLRELA
CCCCCCCCCCHHEECCCCCHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
PLIQALVQPGGKLALSGLLKEQAAEISECYAQWFDMDQPAHKDDWSRLTGVRKSL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
PWIQLRLHSSSEHADAISDLLMDEGSVSITFEDGKDQPIFEPKLGETPLWNDTVVVALF
CEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEE
DADFDLAPVVDMLKSLPFLGSELKYKIEQIEDKDWVREWMDSYHPIQFGKRLWICPSWRE
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHCCEEEECCCCCC
VPDPEAVNVILDPGLAFGTGTHPTTALCLEWLDSLDLAGKDIIDFGCGSGILAVAALKLG
CCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHC
AAKATGIDIDYQAIDASRDNAQRNQVEDRLALYLPEDQPAGLKAEVLVANILAGPLRELA
CCCCCCCCCCHHEECCCCCHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
PLIQALVQPGGKLALSGLLKEQAAEISECYAQWFDMDQPAHKDDWSRLTGVRKSL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA