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The map label for this gene is cidA [H]

Identifier: 119776059

GI number: 119776059

Start: 3481534

End: 3481965

Strand: Reverse

Name: cidA [H]

Synonym: Sama_2927

Alternate gene names: 119776059

Gene position: 3481965-3481534 (Counterclockwise)

Preceding gene: 119776061

Following gene: 119776058

Centisome position: 80.86

GC content: 59.49

Gene sequence:

>432_bases
ATGACCCTCAGCGAAGGCAAAGTCAGACTCAAATCCGGTGCCAAAAGGGCCAGCCTGACCCTGTTGCAGGCGGCGGCTAT
CTGCCTGCTCGCCTGGCTGGCTCATGCTCTGGTGTTGTATTTTTCGCTGCCGGTGCCCGGCGGCGTGGTGGGCCTGGCGG
TATTGTTGGCGCTGTTGTCGCTTAAGTGGGTGCCCGAAAAGGCCTTGCAGGCCGGTGCGGCCTGGCTGCTGGGGGACTTG
CTGCTGTTTTTTATTCCGCCGGTGATATCTGTGATTCAGTATGAGGCCATGATTGAACAATATGGCGCCCGCATGCTGGG
CTTTTTGGTGGCAGGCAGCGTAACCGTGCTCTTGGGTACCGCCTGGGTAGTGGACAAAGCCTTTAAGTTTGAACGTGGCC
TGCACCTGGCCCGTGCCGGAGGGCGACTGTAA

Upstream 100 bases:

>100_bases
GATATCCTTTGGTAATGCTATCTATGCTTAATATTCATTTTTTTTATTTAAATGGCAAATCTACACTAAGCACATTCCAT
TTTTAACTGTGATAGCCACC

Downstream 100 bases:

>100_bases
TGAGTCATACCAGTCTGGCGCTGCTGAGCTTATTGATTACCCTCATGGGCTATTACGGCGCCAAGCGTCTGTACAGCTGC
TTGGGCTACTGGTGGGCCGC

Product: holin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 142

Protein sequence:

>143_residues
MTLSEGKVRLKSGAKRASLTLLQAAAICLLAWLAHALVLYFSLPVPGGVVGLAVLLALLSLKWVPEKALQAGAAWLLGDL
LLFFIPPVISVIQYEAMIEQYGARMLGFLVAGSVTVLLGTAWVVDKAFKFERGLHLARAGGRL

Sequences:

>Translated_143_residues
MTLSEGKVRLKSGAKRASLTLLQAAAICLLAWLAHALVLYFSLPVPGGVVGLAVLLALLSLKWVPEKALQAGAAWLLGDL
LLFFIPPVISVIQYEAMIEQYGARMLGFLVAGSVTVLLGTAWVVDKAFKFERGLHLARAGGRL
>Mature_142_residues
TLSEGKVRLKSGAKRASLTLLQAAAICLLAWLAHALVLYFSLPVPGGVVGLAVLLALLSLKWVPEKALQAGAAWLLGDLL
LFFIPPVISVIQYEAMIEQYGARMLGFLVAGSVTVLLGTAWVVDKAFKFERGLHLARAGGRL

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 15269; Mature: 15137

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSEGKVRLKSGAKRASLTLLQAAAICLLAWLAHALVLYFSLPVPGGVVGLAVLLALLS
CCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LKWVPEKALQAGAAWLLGDLLLFFIPPVISVIQYEAMIEQYGARMLGFLVAGSVTVLLGT
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWVVDKAFKFERGLHLARAGGRL
HHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TLSEGKVRLKSGAKRASLTLLQAAAICLLAWLAHALVLYFSLPVPGGVVGLAVLLALLS
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LKWVPEKALQAGAAWLLGDLLLFFIPPVISVIQYEAMIEQYGARMLGFLVAGSVTVLLGT
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWVVDKAFKFERGLHLARAGGRL
HHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA