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The map label for this gene is cysC

Identifier: 119776020

GI number: 119776020

Start: 3429678

End: 3430274

Strand: Reverse

Name: cysC

Synonym: Sama_2888

Alternate gene names: 119776020

Gene position: 3430274-3429678 (Counterclockwise)

Preceding gene: 119776021

Following gene: 119776014

Centisome position: 79.66

GC content: 56.45

Gene sequence:

>597_bases
ATGAATCATATTGTGTGGCACCAACACGCCATCACCCACAGCGAACGCGCAGCGCAAAAGGGCCATCGCGGTGCCATCCT
CTGGTTTACCGGGCTCTCTGGCGCTGGCAAGAGCACACTCGCCGGTGCTTTGGAAGCCGAATTGTTTCGCCGCGGATTGC
ACTCGTATCTTTTGGATGGCGATAACGTGCGCCACGGCCTGTGTAAAGACTTGGGCTTCAGCCTCGAAGACCGACGGGAG
AACATACGCCGCGTAGGCGAAGTGGCCAAATTGATGCTGGATGCGGGGCTTTTGGTGCTCTCGGCCTTCGTTTCGCCCCA
GCGAGCCGAGCGCGACCTGGTGCGTGCTTTGGTGGGAGAGGGGGAGTTTATTGAGGTGCATGTGGCAACGCCGCTTACCG
TGTGTGAATCCCGCGATCCCAAGGGCCTTTACCAGAAGGCCCGGGCTGGAGAGATTAAAGATTTTACTGGGATTTCTTCG
CCTTATGAGGCACCTGTGAGTGCGGAGTTGGTGATTGATACCAGTGAGGGCGATCTGGATTCTCAGGTGGCGAAGCTGGT
GGATTATTTGATTAGTGGTGGATATATTCCTGCCTGA

Upstream 100 bases:

>100_bases
GGGATCCCCATGGCAATTGCCTACACCTTCGCGGTGCTGGCGTTGATCCCCCTGATGTTCCCGTTCCACAGCCTGTAACG
GTCAGAGGCAAGGAGAGAAA

Downstream 100 bases:

>100_bases
TTGAGCTTTCGGCTTTTGCCTATGGAGTTCCGCCTTGGCTACGGTGTTAGCTGTCACCGGAAATCTAATCTTAAACCTTT
GCAGGTTTGACGCTTTTAAA

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MNHIVWHQHAITHSERAAQKGHRGAILWFTGLSGAGKSTLAGALEAELFRRGLHSYLLDGDNVRHGLCKDLGFSLEDRRE
NIRRVGEVAKLMLDAGLLVLSAFVSPQRAERDLVRALVGEGEFIEVHVATPLTVCESRDPKGLYQKARAGEIKDFTGISS
PYEAPVSAELVIDTSEGDLDSQVAKLVDYLISGGYIPA

Sequences:

>Translated_198_residues
MNHIVWHQHAITHSERAAQKGHRGAILWFTGLSGAGKSTLAGALEAELFRRGLHSYLLDGDNVRHGLCKDLGFSLEDRRE
NIRRVGEVAKLMLDAGLLVLSAFVSPQRAERDLVRALVGEGEFIEVHVATPLTVCESRDPKGLYQKARAGEIKDFTGISS
PYEAPVSAELVIDTSEGDLDSQVAKLVDYLISGGYIPA
>Mature_198_residues
MNHIVWHQHAITHSERAAQKGHRGAILWFTGLSGAGKSTLAGALEAELFRRGLHSYLLDGDNVRHGLCKDLGFSLEDRRE
NIRRVGEVAKLMLDAGLLVLSAFVSPQRAERDLVRALVGEGEFIEVHVATPLTVCESRDPKGLYQKARAGEIKDFTGISS
PYEAPVSAELVIDTSEGDLDSQVAKLVDYLISGGYIPA

Specific function: Catalyzes the synthesis of activated sulfate

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family

Homologues:

Organism=Homo sapiens, GI46094058, Length=203, Percent_Identity=47.7832512315271, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI34447231, Length=202, Percent_Identity=45.5445544554455, Blast_Score=177, Evalue=4e-45,
Organism=Homo sapiens, GI62912492, Length=202, Percent_Identity=45.5445544554455, Blast_Score=177, Evalue=4e-45,
Organism=Escherichia coli, GI1789107, Length=188, Percent_Identity=63.8297872340426, Blast_Score=249, Evalue=7e-68,
Organism=Caenorhabditis elegans, GI17542422, Length=203, Percent_Identity=53.2019704433498, Blast_Score=210, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6322852, Length=197, Percent_Identity=49.746192893401, Blast_Score=196, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24667032, Length=202, Percent_Identity=47.5247524752475, Blast_Score=181, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24667028, Length=202, Percent_Identity=47.5247524752475, Blast_Score=181, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24667036, Length=202, Percent_Identity=47.5247524752475, Blast_Score=181, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24667040, Length=202, Percent_Identity=47.5247524752475, Blast_Score=181, Evalue=3e-46,
Organism=Drosophila melanogaster, GI116007838, Length=202, Percent_Identity=47.5247524752475, Blast_Score=181, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24667044, Length=202, Percent_Identity=47.5247524752475, Blast_Score=181, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSC_SHEAM (A1S9N4)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_928760.1
- ProteinModelPortal:   A1S9N4
- SMR:   A1S9N4
- STRING:   A1S9N4
- GeneID:   4605135
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_2888
- NMPDR:   fig|326297.7.peg.2707
- eggNOG:   COG0529
- HOGENOM:   HBG309946
- OMA:   TVCESRD
- PhylomeDB:   A1S9N4
- ProtClustDB:   PRK03846
- HAMAP:   MF_00065
- InterPro:   IPR002891
- TIGRFAMs:   TIGR00455

Pfam domain/function: PF01583 APS_kinase

EC number: =2.7.1.25

Molecular weight: Translated: 21575; Mature: 21575

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: ACT_SITE 105-105

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHIVWHQHAITHSERAAQKGHRGAILWFTGLSGAGKSTLAGALEAELFRRGLHSYLLDG
CCCCEECHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
DNVRHGLCKDLGFSLEDRRENIRRVGEVAKLMLDAGLLVLSAFVSPQRAERDLVRALVGE
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCC
GEFIEVHVATPLTVCESRDPKGLYQKARAGEIKDFTGISSPYEAPVSAELVIDTSEGDLD
CCEEEEEECCCCHHHCCCCCHHHHHHHHCCCCCHHCCCCCCCCCCCCEEEEEECCCCCHH
SQVAKLVDYLISGGYIPA
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNHIVWHQHAITHSERAAQKGHRGAILWFTGLSGAGKSTLAGALEAELFRRGLHSYLLDG
CCCCEECHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
DNVRHGLCKDLGFSLEDRRENIRRVGEVAKLMLDAGLLVLSAFVSPQRAERDLVRALVGE
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCC
GEFIEVHVATPLTVCESRDPKGLYQKARAGEIKDFTGISSPYEAPVSAELVIDTSEGDLD
CCEEEEEECCCCHHHCCCCCHHHHHHHHCCCCCHHCCCCCCCCCCCCEEEEEECCCCCHH
SQVAKLVDYLISGGYIPA
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA