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The map label for this gene is hlyB [H]

Identifier: 119776012

GI number: 119776012

Start: 3420502

End: 3422178

Strand: Reverse

Name: hlyB [H]

Synonym: Sama_2880

Alternate gene names: 119776012

Gene position: 3422178-3420502 (Counterclockwise)

Preceding gene: 119776013

Following gene: 119776010

Centisome position: 79.47

GC content: 55.22

Gene sequence:

>1677_bases
ATGTCCATATCCATGTCTAATTACAGTCTGAGAAACAAACTTTTGCTGCTGGCCATGGTGCCTTTGGTGCTGATCCTTAC
TGCCGTGATGAGCTATTCCTGGCAGGTTGAGAGCCAGGCGTTGGACGATTCGGTTGCCCTGTTTAAGGAAAAGCTGGTCA
ATGAGCGGCAACAGCAGCTCCAGGAGGCCACCCAGATTGCCCTTGCCGTGGTCGACCACCAGATAAGCCTGGGGCAAAAC
GGCAACATCAATGATGCCCTGCGGCCACTGAGATTTGGCAGCGCCGGTTACTTTTTTATCTATGACTATCAGGGTGCCAA
CGTGTTCCACGCCACCAATCCGGCATTGGAAGGTACACCGCAAATCGGCATGACAGATCCCCAAGGCACCAAGATTGTGG
TGGGGCTTATTGATGCAGCCAAACGTGGCGGCGGCTTTTTTAACTACGTGTATCCCAAACCCGGTGTCGAGGGGTTGGTG
GATAAAATTGGGTATGCGGCTCCCATCCCCGGAAAAGATTGGCTATTGGGCACAGGCGCCTATCTGGATGATATAGACGC
CGCGGTTGACACTTATTCACAAAGTGCCCGTCAGGCCATGTGGGAAAAAGCCGTGGCCATTTTCATGATGTCGCTGGTGC
TTGCCTTTATCACCCTGATAGCCATTTGGAGCGCCGCCCACAGGATGGTGAAGCCCATTCGTGCCATGGTCGACAGCCTG
AACGACATCGCCAAGGGAGAAGGGGATCTTACGGCGCGCCTCAGCGTTCGTGGTGAGGATGAAATCGCTGAGCTCGGCAT
CGCCTTTAACCAATTCGTGGACAAGCTGCAGGGTATTATCCGCGATGTGGCCGATACCACGGGCCGGGTAAAACAGGCGG
CCGTCGATATTGACCGCCAAACTTCGGAGATGGCGAATCAGCTTAACAGTCACAATAACGAAACCGATCAGGTGGTTACC
GCCATCACTGAGATGTCGTCCACTGCCGCCGAGGTGGCACAAAATACCACCCAGGTGGCCGAAGCCACTCAGGCAGCCAC
TGGTGATGTCGCCAAAGCCCAGGCCTGTGTTGATACCTCGCTGGCAGAGATTTCGAACCTGATGTCACAGGTTAACGACG
CGGCGGCCAATATTCAGTCCCTCAGCGAACAGTCGCAAAAGATTAATTCGGTGTTGTCTGTGATTGGTGGCATTGCCGAG
CAAACCAACTTGCTGGCGCTCAATGCGGCCATTGAGGCCGCACGGGCCGGAGAACAGGGCCGGGGCTTTGCGGTGGTGGC
CGACGAAGTGCGTAATCTTGCCAGTCGGACCCAGGCAAGTACTCTGGAAATCAATGAAATGCTTACCGACTTGCACCGCC
TGGTGTCATCTGCCGTGAAAACCATGGATGAGAGCCAGCACAGTTGTCAGCGGTCTGTGGAAGCCTCGACAGCGATTTCT
GAGAGTCTGGGATCGGTGACCAGCGCCGTTACCGCTATCAATGATATGAGCACCCAGATTGCGGCGGCGGCCACCGAGCA
AAGCTCTGTGACCGAAGAGATTAACCGTAATGTGTATGCCATTCAGGAGATAGTGAATGCGTTGCTGGTCTCCAGTCAGG
AGGCAAGAACCGTCAGCCGCACCGTCTCCACCGAAGGGGCCCAGCTCTCCAACCTGGTAGGCCAGTTCAAGGTGTGA

Upstream 100 bases:

>100_bases
GGCAACAAGGTATTGAACACGCCACCATCAGCCTCGAGTAGTAGGGCTATACTCAACACATATAAATCCCGGCGCCGAGA
GCGAATCGAAGGAGAGGTGT

Downstream 100 bases:

>100_bases
TTGTGTTAGCGTGATAAAGGCACCTTCGGGTGCCTTTTTGCTGAATGCTGCTTTGGAATAGGGGGGAATAGGGGGGAATA
GGGAATAGGGAATAGGGAAT

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MSISMSNYSLRNKLLLLAMVPLVLILTAVMSYSWQVESQALDDSVALFKEKLVNERQQQLQEATQIALAVVDHQISLGQN
GNINDALRPLRFGSAGYFFIYDYQGANVFHATNPALEGTPQIGMTDPQGTKIVVGLIDAAKRGGGFFNYVYPKPGVEGLV
DKIGYAAPIPGKDWLLGTGAYLDDIDAAVDTYSQSARQAMWEKAVAIFMMSLVLAFITLIAIWSAAHRMVKPIRAMVDSL
NDIAKGEGDLTARLSVRGEDEIAELGIAFNQFVDKLQGIIRDVADTTGRVKQAAVDIDRQTSEMANQLNSHNNETDQVVT
AITEMSSTAAEVAQNTTQVAEATQAATGDVAKAQACVDTSLAEISNLMSQVNDAAANIQSLSEQSQKINSVLSVIGGIAE
QTNLLALNAAIEAARAGEQGRGFAVVADEVRNLASRTQASTLEINEMLTDLHRLVSSAVKTMDESQHSCQRSVEASTAIS
ESLGSVTSAVTAINDMSTQIAAAATEQSSVTEEINRNVYAIQEIVNALLVSSQEARTVSRTVSTEGAQLSNLVGQFKV

Sequences:

>Translated_558_residues
MSISMSNYSLRNKLLLLAMVPLVLILTAVMSYSWQVESQALDDSVALFKEKLVNERQQQLQEATQIALAVVDHQISLGQN
GNINDALRPLRFGSAGYFFIYDYQGANVFHATNPALEGTPQIGMTDPQGTKIVVGLIDAAKRGGGFFNYVYPKPGVEGLV
DKIGYAAPIPGKDWLLGTGAYLDDIDAAVDTYSQSARQAMWEKAVAIFMMSLVLAFITLIAIWSAAHRMVKPIRAMVDSL
NDIAKGEGDLTARLSVRGEDEIAELGIAFNQFVDKLQGIIRDVADTTGRVKQAAVDIDRQTSEMANQLNSHNNETDQVVT
AITEMSSTAAEVAQNTTQVAEATQAATGDVAKAQACVDTSLAEISNLMSQVNDAAANIQSLSEQSQKINSVLSVIGGIAE
QTNLLALNAAIEAARAGEQGRGFAVVADEVRNLASRTQASTLEINEMLTDLHRLVSSAVKTMDESQHSCQRSVEASTAIS
ESLGSVTSAVTAINDMSTQIAAAATEQSSVTEEINRNVYAIQEIVNALLVSSQEARTVSRTVSTEGAQLSNLVGQFKV
>Mature_557_residues
SISMSNYSLRNKLLLLAMVPLVLILTAVMSYSWQVESQALDDSVALFKEKLVNERQQQLQEATQIALAVVDHQISLGQNG
NINDALRPLRFGSAGYFFIYDYQGANVFHATNPALEGTPQIGMTDPQGTKIVVGLIDAAKRGGGFFNYVYPKPGVEGLVD
KIGYAAPIPGKDWLLGTGAYLDDIDAAVDTYSQSARQAMWEKAVAIFMMSLVLAFITLIAIWSAAHRMVKPIRAMVDSLN
DIAKGEGDLTARLSVRGEDEIAELGIAFNQFVDKLQGIIRDVADTTGRVKQAAVDIDRQTSEMANQLNSHNNETDQVVTA
ITEMSSTAAEVAQNTTQVAEATQAATGDVAKAQACVDTSLAEISNLMSQVNDAAANIQSLSEQSQKINSVLSVIGGIAEQ
TNLLALNAAIEAARAGEQGRGFAVVADEVRNLASRTQASTLEINEMLTDLHRLVSSAVKTMDESQHSCQRSVEASTAISE
SLGSVTSAVTAINDMSTQIAAAATEQSSVTEEINRNVYAIQEIVNALLVSSQEARTVSRTVSTEGAQLSNLVGQFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=375, Percent_Identity=31.7333333333333, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788194, Length=401, Percent_Identity=27.6807980049875, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787690, Length=396, Percent_Identity=30.050505050505, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1788195, Length=297, Percent_Identity=33.6700336700337, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1789453, Length=350, Percent_Identity=30.2857142857143, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59715; Mature: 59584

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISMSNYSLRNKLLLLAMVPLVLILTAVMSYSWQVESQALDDSVALFKEKLVNERQQQL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QEATQIALAVVDHQISLGQNGNINDALRPLRFGSAGYFFIYDYQGANVFHATNPALEGTP
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHEECCCCEEEEEEECCCEEEECCCCCCCCCC
QIGMTDPQGTKIVVGLIDAAKRGGGFFNYVYPKPGVEGLVDKIGYAAPIPGKDWLLGTGA
CCCCCCCCCCEEEEEEHHHHHCCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCEEECCC
YLDDIDAAVDTYSQSARQAMWEKAVAIFMMSLVLAFITLIAIWSAAHRMVKPIRAMVDSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDIAKGEGDLTARLSVRGEDEIAELGIAFNQFVDKLQGIIRDVADTTGRVKQAAVDIDRQ
HHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSEMANQLNSHNNETDQVVTAITEMSSTAAEVAQNTTQVAEATQAATGDVAKAQACVDTS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LAEISNLMSQVNDAAANIQSLSEQSQKINSVLSVIGGIAEQTNLLALNAAIEAARAGEQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
RGFAVVADEVRNLASRTQASTLEINEMLTDLHRLVSSAVKTMDESQHSCQRSVEASTAIS
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLGSVTSAVTAINDMSTQIAAAATEQSSVTEEINRNVYAIQEIVNALLVSSQEARTVSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHH
TVSTEGAQLSNLVGQFKV
HHCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SISMSNYSLRNKLLLLAMVPLVLILTAVMSYSWQVESQALDDSVALFKEKLVNERQQQL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QEATQIALAVVDHQISLGQNGNINDALRPLRFGSAGYFFIYDYQGANVFHATNPALEGTP
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHEECCCCEEEEEEECCCEEEECCCCCCCCCC
QIGMTDPQGTKIVVGLIDAAKRGGGFFNYVYPKPGVEGLVDKIGYAAPIPGKDWLLGTGA
CCCCCCCCCCEEEEEEHHHHHCCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCEEECCC
YLDDIDAAVDTYSQSARQAMWEKAVAIFMMSLVLAFITLIAIWSAAHRMVKPIRAMVDSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDIAKGEGDLTARLSVRGEDEIAELGIAFNQFVDKLQGIIRDVADTTGRVKQAAVDIDRQ
HHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSEMANQLNSHNNETDQVVTAITEMSSTAAEVAQNTTQVAEATQAATGDVAKAQACVDTS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LAEISNLMSQVNDAAANIQSLSEQSQKINSVLSVIGGIAEQTNLLALNAAIEAARAGEQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
RGFAVVADEVRNLASRTQASTLEINEMLTDLHRLVSSAVKTMDESQHSCQRSVEASTAIS
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLGSVTSAVTAINDMSTQIAAAATEQSSVTEEINRNVYAIQEIVNALLVSSQEARTVSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHH
TVSTEGAQLSNLVGQFKV
HHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]