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The map label for this gene is cysH [H]

Identifier: 119775969

GI number: 119775969

Start: 3374612

End: 3375340

Strand: Reverse

Name: cysH [H]

Synonym: Sama_2837

Alternate gene names: 119775969

Gene position: 3375340-3374612 (Counterclockwise)

Preceding gene: 119775970

Following gene: 119775965

Centisome position: 78.38

GC content: 55.69

Gene sequence:

>729_bases
ATGAATTATCACGATTTACTCAGTCTGGACGCAGCCGAGCAAGCGGCCGCGCTTGAGGACATCAATCTACAGCTGGCTAA
GGCCACGCCTACAGAGCGGGTTGAATTTGCGCTGCGTGAATTACCCGGCGAGCATATTTTAAGTTCCAGTTTTGGTATCC
AGGCGGCAGTGATGCTGCATTTGGTGACGCATGTAAAAAGCGATGTGCCTGTGGTGCTGACCGATACCGGGTATTTGTTC
CCGGAAACCTATCGATTTATCGATGAACTGACCGAGCGCCTTAAGCTTAACCTTAAGGTGTACCGCGCCCCGATGACGGC
GGCCTGGCAGGAAGCCCGCTTCGGCAAGCTGTGGGAGCAGGGGCTGGACGGCCTTGAGCGCTACAACCGCATCAACAAGG
TTGAGCCGATGCAGCGGGCACTGGAAGAGCTTGACGTGGGTACCTGGTTTGCTGGTCTGCGCCGCACTCAGGCGTCGACC
CGCGAAGCGCTGCCTATCCTTGCCATTCACGGTAAGCGCTTTAAGTTACTGCCGATTATTGAGTGGAGCAACAAGGATGT
GCATGAATACCTGACCAAGTTCGGGCTGCCCTATCACCCGCTGTGGGAGCAGGGCTATGTATCTGTGGGCGATACTCACT
CCACCAAGCCGCTGGAGCTTGGCATGAGTGAAGAAGACACCCGCTTCAATGGCATGAAGCGCGAGTGCGGCCTGCACTAC
GAGATTTAA

Upstream 100 bases:

>100_bases
TGAGACCAGTCAGGGGGAAGCAAGGCTTCCCCCGTTTGTTTTGGCCGCTCGTTGGCCTGTGCCAAGACGTGAAGCGTCGC
CAGAACCCTTGGAGATAAGC

Downstream 100 bases:

>100_bases
TCCTGCAGGGCAAAGCATTGTGCGCGAGCAAAAAACGCCGGTATTTGCCGGCGTTTTTTATTTTGAATTTCAGCTGCCTT
TGGCGCTTCTGATGGCGGTG

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MNYHDLLSLDAAEQAAALEDINLQLAKATPTERVEFALRELPGEHILSSSFGIQAAVMLHLVTHVKSDVPVVLTDTGYLF
PETYRFIDELTERLKLNLKVYRAPMTAAWQEARFGKLWEQGLDGLERYNRINKVEPMQRALEELDVGTWFAGLRRTQAST
REALPILAIHGKRFKLLPIIEWSNKDVHEYLTKFGLPYHPLWEQGYVSVGDTHSTKPLELGMSEEDTRFNGMKRECGLHY
EI

Sequences:

>Translated_242_residues
MNYHDLLSLDAAEQAAALEDINLQLAKATPTERVEFALRELPGEHILSSSFGIQAAVMLHLVTHVKSDVPVVLTDTGYLF
PETYRFIDELTERLKLNLKVYRAPMTAAWQEARFGKLWEQGLDGLERYNRINKVEPMQRALEELDVGTWFAGLRRTQAST
REALPILAIHGKRFKLLPIIEWSNKDVHEYLTKFGLPYHPLWEQGYVSVGDTHSTKPLELGMSEEDTRFNGMKRECGLHY
EI
>Mature_242_residues
MNYHDLLSLDAAEQAAALEDINLQLAKATPTERVEFALRELPGEHILSSSFGIQAAVMLHLVTHVKSDVPVVLTDTGYLF
PETYRFIDELTERLKLNLKVYRAPMTAAWQEARFGKLWEQGLDGLERYNRINKVEPMQRALEELDVGTWFAGLRRTQAST
REALPILAIHGKRFKLLPIIEWSNKDVHEYLTKFGLPYHPLWEQGYVSVGDTHSTKPLELGMSEEDTRFNGMKRECGLHY
EI

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=239, Percent_Identity=62.7615062761506, Blast_Score=322, Evalue=1e-89,
Organism=Saccharomyces cerevisiae, GI6325425, Length=254, Percent_Identity=31.1023622047244, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR011800
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 27753; Mature: 27753

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYHDLLSLDAAEQAAALEDINLQLAKATPTERVEFALRELPGEHILSSSFGIQAAVMLH
CCHHHHHCCCHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHH
LVTHVKSDVPVVLTDTGYLFPETYRFIDELTERLKLNLKVYRAPMTAAWQEARFGKLWEQ
HHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHH
GLDGLERYNRINKVEPMQRALEELDVGTWFAGLRRTQASTREALPILAIHGKRFKLLPII
HHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEE
EWSNKDVHEYLTKFGLPYHPLWEQGYVSVGDTHSTKPLELGMSEEDTRFNGMKRECGLHY
ECCCCCHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCEECCCCCCCHHHCCCHHHCCCCC
EI
CC
>Mature Secondary Structure
MNYHDLLSLDAAEQAAALEDINLQLAKATPTERVEFALRELPGEHILSSSFGIQAAVMLH
CCHHHHHCCCHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHH
LVTHVKSDVPVVLTDTGYLFPETYRFIDELTERLKLNLKVYRAPMTAAWQEARFGKLWEQ
HHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHH
GLDGLERYNRINKVEPMQRALEELDVGTWFAGLRRTQASTREALPILAIHGKRFKLLPII
HHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEE
EWSNKDVHEYLTKFGLPYHPLWEQGYVSVGDTHSTKPLELGMSEEDTRFNGMKRECGLHY
ECCCCCHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCEECCCCCCCHHHCCCHHHCCCCC
EI
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]