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The map label for this gene is tkt1 [H]

Identifier: 119775891

GI number: 119775891

Start: 3298852

End: 3300843

Strand: Reverse

Name: tkt1 [H]

Synonym: Sama_2759

Alternate gene names: 119775891

Gene position: 3300843-3298852 (Counterclockwise)

Preceding gene: 119775893

Following gene: 119775890

Centisome position: 76.65

GC content: 57.93

Gene sequence:

>1992_bases
ATGTCTCGTAAAGAACTCGCCAACGCTATCCGCGCACTCAGCATGGACGCCGTTCAAAAGGCCAACTCCGGTCACCCCGG
TGCCCCCATGGGGATGGCAGATATTGCCGAAGTCCTTTGGCGCGGTCATCTGAAGCACAACCCCACCAATCCACAGTGGG
CCGATCGCGACCGTTTCATCCTCTCCAATGGCCACGGCTCCATGCTGCACTATTCGCTGCTGCACCTGGCCGGTTATGAC
CTGTCTATTGAAGACCTCAAGCAGTTCCGTCAGTTGCACTCACGCACCCCAGGTCACCCTGAGTACGGTTATGCCCCCGG
TATCGAAACCACCACAGGCCCTCTGGGTCAGGGCATCACCAACGGCGTGGGTATGGCCATTGCTGAGAAAGTGCTGGCTG
CCCAGTTTAACCGTGACGGTCACGACATCGTTGACCACTACACCTACGTGTTCATGGGCGATGGCTGCTTGATGGAAGGT
ATTTCCCACGAGGCTTGCTCTTTGGCAGGTACCCTGGGTCTGGGCAAACTGATTGCTTTCTGGGATGACAACGGCATCTC
TATCGACGGTCACGTTGAAGGCTGGTTTACCGACGACACGCCAAAGCGTTTCGAATCTTACGGCTGGCATGTAATTGCCG
GTGTTGACGGCCACGATGCCGACGCCATCGACGCGGCCATCAAGGCGGCCAAGGCCGACCCACGTCCAACCCTGATTTGC
TGCAAAACCATCATTGGTTACGGCTCGCCAAACAAGTCCGGTTCACACGACTGCCACGGCGCGCCGCTGGGCGATGCTGA
AATCGCTGCCGCCCGTGAATTCCTCGGCTGGAAACACGACCCATTCGTTATTCCTGCTGATATTTATGCCCAGTGGGATG
CCAAAGAAGCCGGTATTGCCTCTGAGAAAGCCTGGGACGAAAAGTTTGCCGCCTACGCCGCTGCTTACCCAGAGCTGGCT
GCTGAATACCAGCGCCGCGTGAAGGGTGAACTGCCTGCCAACTTCGCTACCGAAGCCCAGGCCTACATCGAGAAGCTGCA
GAACAACCCTGCCAACATCGCTTCCCGTAAAGCCTCGCAAAATGCTCTGGAAGCCTTCGGCGCCATGCTGCCTGAATTCC
TCGGCGGCAGTGCTGACCTGGCCCCATCCAACCTGACCATGTACTCGGCTTCCAAATCCATCACAGGTGCTGATGCCAGT
GGTAACTACCTGCACTATGGTGTGCGCGAGTTCGGTATGACCGCCATCATCAACGGTATCGCGCTGCACGGCGGCTTTGT
GCCATACGGCGCCACCTTCCTGATGTTTATGGAATATGCCCGTAACGCCATGCGTATGGCTGCCCTGATGAAGGTGCAGA
ACATCCAGGTTTACACCCACGACTCTATCGGTCTGGGTGAAGACGGCCCGACTCACCAGCCAGTAGAGCAAATCGCTTCT
CTGCGCGTGACCCCGAACATGAGCACCTGGCGCCCATGTGACCAGGTGGAATCAGCCGTGGCCTGGAAATACGCCATCGA
GCGCAAAGACGGCCCAACGTCGCTGATCTTCTCCCGTCAGAACCTGGCGCAAATGCCACGCAGCGCTGAGCAGCTGGCCA
ATGTCGCCAAGGGCGGTTATGTGCTGGTAGACAGCGCTGCAGCCCCTGAACTCATCATCATTGCCACCGGCTCTGAAGTT
GAGCTGGCAGTGAAAGCCCAGGCCGAGCTGACCGCCAAGGGCAAGCAGGTGCGCGTGGTGTCCATGCCATCTACCGACGT
GTTCGACAAGCAGGATGCGGCCTATAAAGAAGCCGTACTGCCAGCCAGCGTCACAAAACGTGTGGCCGTAGAAGCGGGTA
TTGCCGATTACTGGTATAAGTATGTGGGTCTGAACGGCCGCATCATCGGCATGACCAGCTTCGGCGAGTCAGCGCCAGCC
AATCAGCTGTTTGAAATGTTCGGCTTCACCGTCGACAAGGTGGTTGCCGCCGCCGAAGAGCTGCTGGGTTAA

Upstream 100 bases:

>100_bases
GCCGTCAATATGGAAATTTAAATTTGCGTCCACAAGCCCTGTTAAGGGAAAATATGTGCCCACAATTGCCCGAAAAGCCT
CAATACAAGCAGGAGAGAGC

Downstream 100 bases:

>100_bases
TTCTGACGCGAGCAAGGTGGCAGCCAGGCTGCCACCGGTCTGACCGGCAAATGCCGGTCAGCCTCTGTCGGCAGGGGAGC
CGACAGGGTTTTCACCCTCC

Product: transketolase

Products: NA

Alternate protein names: TK 1 [H]

Number of amino acids: Translated: 663; Mature: 662

Protein sequence:

>663_residues
MSRKELANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWRGHLKHNPTNPQWADRDRFILSNGHGSMLHYSLLHLAGYD
LSIEDLKQFRQLHSRTPGHPEYGYAPGIETTTGPLGQGITNGVGMAIAEKVLAAQFNRDGHDIVDHYTYVFMGDGCLMEG
ISHEACSLAGTLGLGKLIAFWDDNGISIDGHVEGWFTDDTPKRFESYGWHVIAGVDGHDADAIDAAIKAAKADPRPTLIC
CKTIIGYGSPNKSGSHDCHGAPLGDAEIAAAREFLGWKHDPFVIPADIYAQWDAKEAGIASEKAWDEKFAAYAAAYPELA
AEYQRRVKGELPANFATEAQAYIEKLQNNPANIASRKASQNALEAFGAMLPEFLGGSADLAPSNLTMYSASKSITGADAS
GNYLHYGVREFGMTAIINGIALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQPVEQIAS
LRVTPNMSTWRPCDQVESAVAWKYAIERKDGPTSLIFSRQNLAQMPRSAEQLANVAKGGYVLVDSAAAPELIIIATGSEV
ELAVKAQAELTAKGKQVRVVSMPSTDVFDKQDAAYKEAVLPASVTKRVAVEAGIADYWYKYVGLNGRIIGMTSFGESAPA
NQLFEMFGFTVDKVVAAAEELLG

Sequences:

>Translated_663_residues
MSRKELANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWRGHLKHNPTNPQWADRDRFILSNGHGSMLHYSLLHLAGYD
LSIEDLKQFRQLHSRTPGHPEYGYAPGIETTTGPLGQGITNGVGMAIAEKVLAAQFNRDGHDIVDHYTYVFMGDGCLMEG
ISHEACSLAGTLGLGKLIAFWDDNGISIDGHVEGWFTDDTPKRFESYGWHVIAGVDGHDADAIDAAIKAAKADPRPTLIC
CKTIIGYGSPNKSGSHDCHGAPLGDAEIAAAREFLGWKHDPFVIPADIYAQWDAKEAGIASEKAWDEKFAAYAAAYPELA
AEYQRRVKGELPANFATEAQAYIEKLQNNPANIASRKASQNALEAFGAMLPEFLGGSADLAPSNLTMYSASKSITGADAS
GNYLHYGVREFGMTAIINGIALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQPVEQIAS
LRVTPNMSTWRPCDQVESAVAWKYAIERKDGPTSLIFSRQNLAQMPRSAEQLANVAKGGYVLVDSAAAPELIIIATGSEV
ELAVKAQAELTAKGKQVRVVSMPSTDVFDKQDAAYKEAVLPASVTKRVAVEAGIADYWYKYVGLNGRIIGMTSFGESAPA
NQLFEMFGFTVDKVVAAAEELLG
>Mature_662_residues
SRKELANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWRGHLKHNPTNPQWADRDRFILSNGHGSMLHYSLLHLAGYDL
SIEDLKQFRQLHSRTPGHPEYGYAPGIETTTGPLGQGITNGVGMAIAEKVLAAQFNRDGHDIVDHYTYVFMGDGCLMEGI
SHEACSLAGTLGLGKLIAFWDDNGISIDGHVEGWFTDDTPKRFESYGWHVIAGVDGHDADAIDAAIKAAKADPRPTLICC
KTIIGYGSPNKSGSHDCHGAPLGDAEIAAAREFLGWKHDPFVIPADIYAQWDAKEAGIASEKAWDEKFAAYAAAYPELAA
EYQRRVKGELPANFATEAQAYIEKLQNNPANIASRKASQNALEAFGAMLPEFLGGSADLAPSNLTMYSASKSITGADASG
NYLHYGVREFGMTAIINGIALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQPVEQIASL
RVTPNMSTWRPCDQVESAVAWKYAIERKDGPTSLIFSRQNLAQMPRSAEQLANVAKGGYVLVDSAAAPELIIIATGSEVE
LAVKAQAELTAKGKQVRVVSMPSTDVFDKQDAAYKEAVLPASVTKRVAVEAGIADYWYKYVGLNGRIIGMTSFGESAPAN
QLFEMFGFTVDKVVAAAEELLG

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=674, Percent_Identity=26.5578635014837, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI4507521, Length=674, Percent_Identity=26.5578635014837, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI133778974, Length=670, Percent_Identity=24.9253731343284, Blast_Score=143, Evalue=6e-34,
Organism=Escherichia coli, GI48994911, Length=662, Percent_Identity=78.0966767371601, Blast_Score=1091, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=664, Percent_Identity=69.1265060240964, Blast_Score=985, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=676, Percent_Identity=24.7041420118343, Blast_Score=157, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6325331, Length=670, Percent_Identity=48.0597014925373, Blast_Score=589, Evalue=1e-169,
Organism=Saccharomyces cerevisiae, GI6319593, Length=673, Percent_Identity=43.9821693907875, Blast_Score=536, Evalue=1e-153,
Organism=Drosophila melanogaster, GI45551847, Length=677, Percent_Identity=26.2924667651403, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI45550715, Length=677, Percent_Identity=26.2924667651403, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24645119, Length=643, Percent_Identity=25.5054432348367, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24666278, Length=515, Percent_Identity=25.2427184466019, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 71540; Mature: 71409

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKELANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWRGHLKHNPTNPQWADRDRFI
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEE
LSNGHGSMLHYSLLHLAGYDLSIEDLKQFRQLHSRTPGHPEYGYAPGIETTTGPLGQGIT
EECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHH
NGVGMAIAEKVLAAQFNRDGHDIVDHYTYVFMGDGCLMEGISHEACSLAGTLGLGKLIAF
CCHHHHHHHHHHHHHHCCCCHHHHHCEEEEEECCCHHHHCCCHHHHHHHHHHCCCCEEEE
WDDNGISIDGHVEGWFTDDTPKRFESYGWHVIAGVDGHDADAIDAAIKAAKADPRPTLIC
ECCCCEEECCCEEEEECCCCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCHHHH
CKTIIGYGSPNKSGSHDCHGAPLGDAEIAAAREFLGWKHDPFVIPADIYAQWDAKEAGIA
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEHHHHEECCCCCCCCC
SEKAWDEKFAAYAAAYPELAAEYQRRVKGELPANFATEAQAYIEKLQNNPANIASRKASQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
NALEAFGAMLPEFLGGSADLAPSNLTMYSASKSITGADASGNYLHYGVREFGMTAIINGI
HHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECHHHHHHHHHHHHH
ALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQPVEQIAS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCHHHHHHHH
LRVTPNMSTWRPCDQVESAVAWKYAIERKDGPTSLIFSRQNLAQMPRSAEQLANVAKGGY
EECCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCEEEEHHHHHHCCHHHHHHHHHHCCCE
VLVDSAAAPELIIIATGSEVELAVKAQAELTAKGKQVRVVSMPSTDVFDKQDAAYKEAVL
EEEECCCCCCEEEEEECCCEEEEEEECHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHCC
PASVTKRVAVEAGIADYWYKYVGLNGRIIGMTSFGESAPANQLFEMFGFTVDKVVAAAEE
CHHHHHHHHHHHCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHH
LLG
HCC
>Mature Secondary Structure 
SRKELANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWRGHLKHNPTNPQWADRDRFI
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEE
LSNGHGSMLHYSLLHLAGYDLSIEDLKQFRQLHSRTPGHPEYGYAPGIETTTGPLGQGIT
EECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHH
NGVGMAIAEKVLAAQFNRDGHDIVDHYTYVFMGDGCLMEGISHEACSLAGTLGLGKLIAF
CCHHHHHHHHHHHHHHCCCCHHHHHCEEEEEECCCHHHHCCCHHHHHHHHHHCCCCEEEE
WDDNGISIDGHVEGWFTDDTPKRFESYGWHVIAGVDGHDADAIDAAIKAAKADPRPTLIC
ECCCCEEECCCEEEEECCCCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCHHHH
CKTIIGYGSPNKSGSHDCHGAPLGDAEIAAAREFLGWKHDPFVIPADIYAQWDAKEAGIA
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEHHHHEECCCCCCCCC
SEKAWDEKFAAYAAAYPELAAEYQRRVKGELPANFATEAQAYIEKLQNNPANIASRKASQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
NALEAFGAMLPEFLGGSADLAPSNLTMYSASKSITGADASGNYLHYGVREFGMTAIINGI
HHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECHHHHHHHHHHHHH
ALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQPVEQIAS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCHHHHHHHH
LRVTPNMSTWRPCDQVESAVAWKYAIERKDGPTSLIFSRQNLAQMPRSAEQLANVAKGGY
EECCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCEEEEHHHHHHCCHHHHHHHHHHCCCE
VLVDSAAAPELIIIATGSEVELAVKAQAELTAKGKQVRVVSMPSTDVFDKQDAAYKEAVL
EEEECCCCCCEEEEEECCCEEEEEEECHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHCC
PASVTKRVAVEAGIADYWYKYVGLNGRIIGMTSFGESAPANQLFEMFGFTVDKVVAAAEE
CHHHHHHHHHHHCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHH
LLG
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]