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The map label for this gene is dsbC [H]

Identifier: 119775870

GI number: 119775870

Start: 3271872

End: 3272600

Strand: Reverse

Name: dsbC [H]

Synonym: Sama_2738

Alternate gene names: 119775870

Gene position: 3272600-3271872 (Counterclockwise)

Preceding gene: 119775871

Following gene: 119775869

Centisome position: 76.0

GC content: 53.77

Gene sequence:

>729_bases
ATGAAACTCACCCGTACCCTGACGCTTTTGGGCTCACTGGCCCTGGCTCCCTTGGTGATGGCGGCCCCTGCCACACCAAA
CGACATGCTGAAGCAGAAAATTCAAAGCACCCTCGGCCTGGAAGTGAACAGCATCACAGCCTCTCCGGTTGAGGGGCTGT
ATCAGGCCATAACCAACCGTGGTGTGTTGTACATCACTGCCGATGGCAGCAAGCTGATCCATGGCAACATCTATGATTTG
AATAACCAGATGAACAACCTGACCGAAAAGGCCCTGGCTGGTCCGCGTCTGGACATGCTCAAAGAATTTGAAAGCAAGAT
GTTGGTGTATAAAGCTAAAGACGAAAAACACGTAGTCACTGTCTTTACCGACATTACCTGCGGTTACTGCCGCAAGCTGC
ATCGTGAGATGAAAGACTATAACGACCTTGGGATAACCGTGCGTTATCTGGCGTATCCCCGCCAGGGCGTACCTTCGCCC
AATGCCGACGAGATGGAAGCCGTATGGTGTGCCAAAGACCCACACAAGGCCATGGACGATGCCAAGGCCGGTAAAAATAT
CAGCCTCGCCAAGTGTGATGCGGACATTGCCGGCCAGTACAACCTGGGTGGTTCCTTTGGCGTAAATGGCACCCCCGCCA
TTGTGCTGGAAGACGGCTCCATGATCCCCGGTTATCAACCTGCCTCCGCGCTGTTTGATGTGCTGGAGCAGCGTGCGGTT
AAGCAGTAA

Upstream 100 bases:

>100_bases
GGCTAATTTGCTTTTGTTACCGTTAGACGGTAACTTTTCAGGCCATTCGCGGGTCTTATAATCAAGAGACTATACCCGCA
GTCGTATTCAAGGATTCAAG

Downstream 100 bases:

>100_bases
CAGCGTGCTGCCTCCCAGAAAAGGTGAGCCCAGGCTCACCTTTTTGTTGTATTGGTATTCCCCAAGGTTCAAGCAAGGAG
TCATTGCGTGAAGTACAAGC

Product: thiol:disulfide interchange protein DsbC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MKLTRTLTLLGSLALAPLVMAAPATPNDMLKQKIQSTLGLEVNSITASPVEGLYQAITNRGVLYITADGSKLIHGNIYDL
NNQMNNLTEKALAGPRLDMLKEFESKMLVYKAKDEKHVVTVFTDITCGYCRKLHREMKDYNDLGITVRYLAYPRQGVPSP
NADEMEAVWCAKDPHKAMDDAKAGKNISLAKCDADIAGQYNLGGSFGVNGTPAIVLEDGSMIPGYQPASALFDVLEQRAV
KQ

Sequences:

>Translated_242_residues
MKLTRTLTLLGSLALAPLVMAAPATPNDMLKQKIQSTLGLEVNSITASPVEGLYQAITNRGVLYITADGSKLIHGNIYDL
NNQMNNLTEKALAGPRLDMLKEFESKMLVYKAKDEKHVVTVFTDITCGYCRKLHREMKDYNDLGITVRYLAYPRQGVPSP
NADEMEAVWCAKDPHKAMDDAKAGKNISLAKCDADIAGQYNLGGSFGVNGTPAIVLEDGSMIPGYQPASALFDVLEQRAV
KQ
>Mature_242_residues
MKLTRTLTLLGSLALAPLVMAAPATPNDMLKQKIQSTLGLEVNSITASPVEGLYQAITNRGVLYITADGSKLIHGNIYDL
NNQMNNLTEKALAGPRLDMLKEFESKMLVYKAKDEKHVVTVFTDITCGYCRKLHREMKDYNDLGITVRYLAYPRQGVPSP
NADEMEAVWCAKDPHKAMDDAKAGKNISLAKCDADIAGQYNLGGSFGVNGTPAIVLEDGSMIPGYQPASALFDVLEQRAV
KQ

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=216, Percent_Identity=50.462962962963, Blast_Score=227, Evalue=7e-61,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 26396; Mature: 26396

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTRTLTLLGSLALAPLVMAAPATPNDMLKQKIQSTLGLEVNSITASPVEGLYQAITNR
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHCC
GVLYITADGSKLIHGNIYDLNNQMNNLTEKALAGPRLDMLKEFESKMLVYKAKDEKHVVT
CEEEEEECCCEEEECCEEECCHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCCEEEE
VFTDITCGYCRKLHREMKDYNDLGITVRYLAYPRQGVPSPNADEMEAVWCAKDPHKAMDD
EEECCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHH
AKAGKNISLAKCDADIAGQYNLGGSFGVNGTPAIVLEDGSMIPGYQPASALFDVLEQRAV
HHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHC
KQ
CC
>Mature Secondary Structure
MKLTRTLTLLGSLALAPLVMAAPATPNDMLKQKIQSTLGLEVNSITASPVEGLYQAITNR
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHCC
GVLYITADGSKLIHGNIYDLNNQMNNLTEKALAGPRLDMLKEFESKMLVYKAKDEKHVVT
CEEEEEECCCEEEECCEEECCHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCCEEEE
VFTDITCGYCRKLHREMKDYNDLGITVRYLAYPRQGVPSPNADEMEAVWCAKDPHKAMDD
EEECCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHH
AKAGKNISLAKCDADIAGQYNLGGSFGVNGTPAIVLEDGSMIPGYQPASALFDVLEQRAV
HHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHC
KQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]