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The map label for this gene is dsbD [H]

Identifier: 119775845

GI number: 119775845

Start: 3244382

End: 3246451

Strand: Reverse

Name: dsbD [H]

Synonym: Sama_2713

Alternate gene names: 119775845

Gene position: 3246451-3244382 (Counterclockwise)

Preceding gene: 119775846

Following gene: 119775843

Centisome position: 75.39

GC content: 57.92

Gene sequence:

>2070_bases
ATGAAAATCATCACCTTTTGGTTTCACATCCTCGTGGGTTGCATCCTGTTGGCATGTTTGCCTGCAATGGCAAGCGACGG
CCCGGACCAAAAGATAGCGGCATCGCTGCTGCTGGAATCAAACACTCCGGCGTCCGGGACCCAGACCTCCCTGGCTGTCC
GTATGTCGCCCGAAGCGGGATGGCACGGTTATTGGCTCAACCCCGGTGACGCCGGTTTCCCGCTGCAGCTGCAATGGCAA
CTGCCGGAGGGGGTCACAGTGGGAGAACTGCAATATCCTGCCCCCGAGTCCCTGTTGATAAGCGGCATGATGAATTACAT
CTATCACGGTGACTATGCCTTGCTGGCACCACTGCAGATTGCCGATGACATCGCCGCGGGTACCGCCATTGATGTTGCGG
TGGAACTGCGCTATCTGGTGTGCAGTCCCACGCTGTGTTTACCCGAGCAGCAGCGGCTCGAAACCCACTTTATTGTTGGC
GACAAGGGCGCGCCCAAGACACAGCAGGCCGCCTTTAATGTCTGGCGTCAAGCTATCCCAAAACCCGTGGCGGCCAGCGC
TGATTTCACTGTCCGCGATGGGCTATTTGTGTTGTCGCTGCCCCTGCCCGAAACCGCTTCCGTGACTGATAATCTGCACT
TTTACCCTGAGGTCAATGGCGCGCTGTCCAATACGGCGCCGCAATCCTTTGTGCAAAAGGGTGACCGCCTCTTTATGCAG
ACCCAGGCCGGTGAGGGGGATGTCAGTGACTTTCATGGGGTGCTGACACTGGATAAAGGCCTGGCTATCCGGGTCAAGGC
GACCGGGCAGGCGGGCGGTGCATTGATGTTCCCAACCGAAGCCGGTTTACCGGCTGCGCAAGAGGGCTCGCTGCTGTCCC
TGTCTGTGGTGGCCGTGTTGGGAGCCGTGCTCGGAGGATTACTGCTGAATCTGATGCCCTGCGTCTTTCCCATTCTCAGC
TTAAAAGTGCTGAGTCTGACTCACATGGGGGACGAGCGACTTGCCCGGCGCGGCGCTGTGGCATACACACTCGGCGCCGT
CTTGGTGTGCGTAATGCTGGGAGCCCTTATTCTGGTGCTGCGGCAGTTCGGTTTACAGGTGGGCTGGGCCTTTCAATTGC
AGCGGCCTGAAATCATAGTGGCGCTTATTCTACTGATGATGGCCATAGGGCTGAATCTGGCCGGTTTGTTTGAAATGGGC
ACCCTGAGTTCGGGCAGTCGCCTGCAGCAGCAACAAGGACCGGCGGGGGATTTTTGGACCGGTGTGCTGGCTGCCTTTGT
GGCCACCCCCTGTACCGGGCCTTTTATGGCCACAGCTCTGGGGGCGGCGCTGGTGCTGCCGGCTTACGTTGGGCTCATGG
TGTTTGCCGGTTTGGGTCTGGGCATGGCTTTGCCCTTTTTGCTGGTGGGCTTTGTACCGGCACTGCGTCAGCGAATGCCT
AAGCCCGGTGCCTGGATGGTGACAGCGAAACGCATTTTTGCTGTGCCCATGTTGCTTACGGCCCTTGGACTGGTGTGGGT
GCTGATGCAGCAGACTGACCGCCAATATGTGTTTGTTGCCTTGCTGCTGGCAATGCTGCTGGGTCTTGCTCTCTGGCTGA
TGGGATTGCTCCAGCATGGGGGCCGAGAGAGGCCCTGGTGGCCAGCGCTGCTGGCGGTCATTATTGTCGCCGGCACCCTG
CTCAGCGTATCGCCGGGGGCAGAGACTCAGATATCGAAGGCAGGTGCCGAGACAAACAGGCCACTGACATTTAACGAGAA
GGACTTGTCGGCGCTGATCATGGAGCAGGATGTGTTTGTGTATTTCAGTGCCGATTGGTGCCTGACCTGTAAAGTGAATG
AAACAACGGCCATTGAGCGGCAGGACACCCAGGCGGCCTTCGAGCGTGCAGGGATGGCCGTGATGCTGGGCGACTGGACC
AATGGCGACCCGCAGATTACCGAGTTTCTTGCAAAACATCAGCGTTCTGGTGTGCCTTTATATCTTTGGTATAAAAAGGG
AAATCTACAGCCAGAGGTGTTGCCGCAAATACTGACATCCTCACTGCTGATTGAAAGGGCGGGTGGTTGA

Upstream 100 bases:

>100_bases
AGCACCATAACGTCAGGCCCCTTTCAGCGCGACCCGCAGTTACTTCACAGGGTTGGATGACAGGGGACTGACACTCAGGA
CTTGGAGTACAGGCTATACC

Downstream 100 bases:

>100_bases
GGCCGGGCGCCCTGAGGATGCTGTGTCAGGGCGCTTGTCGACTTTCCTTCTTTGGTGCTGCAGGTTCGTTGGATGGAGTT
ACTTTGGTGCCTTGCCGGAC

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 689; Mature: 689

Protein sequence:

>689_residues
MKIITFWFHILVGCILLACLPAMASDGPDQKIAASLLLESNTPASGTQTSLAVRMSPEAGWHGYWLNPGDAGFPLQLQWQ
LPEGVTVGELQYPAPESLLISGMMNYIYHGDYALLAPLQIADDIAAGTAIDVAVELRYLVCSPTLCLPEQQRLETHFIVG
DKGAPKTQQAAFNVWRQAIPKPVAASADFTVRDGLFVLSLPLPETASVTDNLHFYPEVNGALSNTAPQSFVQKGDRLFMQ
TQAGEGDVSDFHGVLTLDKGLAIRVKATGQAGGALMFPTEAGLPAAQEGSLLSLSVVAVLGAVLGGLLLNLMPCVFPILS
LKVLSLTHMGDERLARRGAVAYTLGAVLVCVMLGALILVLRQFGLQVGWAFQLQRPEIIVALILLMMAIGLNLAGLFEMG
TLSSGSRLQQQQGPAGDFWTGVLAAFVATPCTGPFMATALGAALVLPAYVGLMVFAGLGLGMALPFLLVGFVPALRQRMP
KPGAWMVTAKRIFAVPMLLTALGLVWVLMQQTDRQYVFVALLLAMLLGLALWLMGLLQHGGRERPWWPALLAVIIVAGTL
LSVSPGAETQISKAGAETNRPLTFNEKDLSALIMEQDVFVYFSADWCLTCKVNETTAIERQDTQAAFERAGMAVMLGDWT
NGDPQITEFLAKHQRSGVPLYLWYKKGNLQPEVLPQILTSSLLIERAGG

Sequences:

>Translated_689_residues
MKIITFWFHILVGCILLACLPAMASDGPDQKIAASLLLESNTPASGTQTSLAVRMSPEAGWHGYWLNPGDAGFPLQLQWQ
LPEGVTVGELQYPAPESLLISGMMNYIYHGDYALLAPLQIADDIAAGTAIDVAVELRYLVCSPTLCLPEQQRLETHFIVG
DKGAPKTQQAAFNVWRQAIPKPVAASADFTVRDGLFVLSLPLPETASVTDNLHFYPEVNGALSNTAPQSFVQKGDRLFMQ
TQAGEGDVSDFHGVLTLDKGLAIRVKATGQAGGALMFPTEAGLPAAQEGSLLSLSVVAVLGAVLGGLLLNLMPCVFPILS
LKVLSLTHMGDERLARRGAVAYTLGAVLVCVMLGALILVLRQFGLQVGWAFQLQRPEIIVALILLMMAIGLNLAGLFEMG
TLSSGSRLQQQQGPAGDFWTGVLAAFVATPCTGPFMATALGAALVLPAYVGLMVFAGLGLGMALPFLLVGFVPALRQRMP
KPGAWMVTAKRIFAVPMLLTALGLVWVLMQQTDRQYVFVALLLAMLLGLALWLMGLLQHGGRERPWWPALLAVIIVAGTL
LSVSPGAETQISKAGAETNRPLTFNEKDLSALIMEQDVFVYFSADWCLTCKVNETTAIERQDTQAAFERAGMAVMLGDWT
NGDPQITEFLAKHQRSGVPLYLWYKKGNLQPEVLPQILTSSLLIERAGG
>Mature_689_residues
MKIITFWFHILVGCILLACLPAMASDGPDQKIAASLLLESNTPASGTQTSLAVRMSPEAGWHGYWLNPGDAGFPLQLQWQ
LPEGVTVGELQYPAPESLLISGMMNYIYHGDYALLAPLQIADDIAAGTAIDVAVELRYLVCSPTLCLPEQQRLETHFIVG
DKGAPKTQQAAFNVWRQAIPKPVAASADFTVRDGLFVLSLPLPETASVTDNLHFYPEVNGALSNTAPQSFVQKGDRLFMQ
TQAGEGDVSDFHGVLTLDKGLAIRVKATGQAGGALMFPTEAGLPAAQEGSLLSLSVVAVLGAVLGGLLLNLMPCVFPILS
LKVLSLTHMGDERLARRGAVAYTLGAVLVCVMLGALILVLRQFGLQVGWAFQLQRPEIIVALILLMMAIGLNLAGLFEMG
TLSSGSRLQQQQGPAGDFWTGVLAAFVATPCTGPFMATALGAALVLPAYVGLMVFAGLGLGMALPFLLVGFVPALRQRMP
KPGAWMVTAKRIFAVPMLLTALGLVWVLMQQTDRQYVFVALLLAMLLGLALWLMGLLQHGGRERPWWPALLAVIIVAGTL
LSVSPGAETQISKAGAETNRPLTFNEKDLSALIMEQDVFVYFSADWCLTCKVNETTAIERQDTQAAFERAGMAVMLGDWT
NGDPQITEFLAKHQRSGVPLYLWYKKGNLQPEVLPQILTSSLLIERAGG

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=407, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 73976; Mature: 73976

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIITFWFHILVGCILLACLPAMASDGPDQKIAASLLLESNTPASGTQTSLAVRMSPEAG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCC
WHGYWLNPGDAGFPLQLQWQLPEGVTVGELQYPAPESLLISGMMNYIYHGDYALLAPLQI
CCCEEECCCCCCCCEEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHH
ADDIAAGTAIDVAVELRYLVCSPTLCLPEQQRLETHFIVGDKGAPKTQQAAFNVWRQAIP
HHHHHCCCHHHHHHEEEHHEECCCCCCCCHHCCCEEEEECCCCCCHHHHHHHHHHHHHCC
KPVAASADFTVRDGLFVLSLPLPETASVTDNLHFYPEVNGALSNTAPQSFVQKGDRLFMQ
CCCCCCCCCEEECCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHCCCEEEEE
TQAGEGDVSDFHGVLTLDKGLAIRVKATGQAGGALMFPTEAGLPAAQEGSLLSLSVVAVL
ECCCCCCCCCCCCEEEECCCEEEEEEECCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHH
GAVLGGLLLNLMPCVFPILSLKVLSLTHMGDERLARRGAVAYTLGAVLVCVMLGALILVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RQFGLQVGWAFQLQRPEIIVALILLMMAIGLNLAGLFEMGTLSSGSRLQQQQGPAGDFWT
HHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHCCCCCHHHH
GVLAAFVATPCTGPFMATALGAALVLPAYVGLMVFAGLGLGMALPFLLVGFVPALRQRMP
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KPGAWMVTAKRIFAVPMLLTALGLVWVLMQQTDRQYVFVALLLAMLLGLALWLMGLLQHG
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GRERPWWPALLAVIIVAGTLLSVSPGAETQISKAGAETNRPLTFNEKDLSALIMEQDVFV
CCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCEECHHHHHHHEEECCEEE
YFSADWCLTCKVNETTAIERQDTQAAFERAGMAVMLGDWTNGDPQITEFLAKHQRSGVPL
EEECCEEEEEEECCCCCCCCHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHCCCCCE
YLWYKKGNLQPEVLPQILTSSLLIERAGG
EEEEECCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIITFWFHILVGCILLACLPAMASDGPDQKIAASLLLESNTPASGTQTSLAVRMSPEAG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCC
WHGYWLNPGDAGFPLQLQWQLPEGVTVGELQYPAPESLLISGMMNYIYHGDYALLAPLQI
CCCEEECCCCCCCCEEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHH
ADDIAAGTAIDVAVELRYLVCSPTLCLPEQQRLETHFIVGDKGAPKTQQAAFNVWRQAIP
HHHHHCCCHHHHHHEEEHHEECCCCCCCCHHCCCEEEEECCCCCCHHHHHHHHHHHHHCC
KPVAASADFTVRDGLFVLSLPLPETASVTDNLHFYPEVNGALSNTAPQSFVQKGDRLFMQ
CCCCCCCCCEEECCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHCCCEEEEE
TQAGEGDVSDFHGVLTLDKGLAIRVKATGQAGGALMFPTEAGLPAAQEGSLLSLSVVAVL
ECCCCCCCCCCCCEEEECCCEEEEEEECCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHH
GAVLGGLLLNLMPCVFPILSLKVLSLTHMGDERLARRGAVAYTLGAVLVCVMLGALILVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RQFGLQVGWAFQLQRPEIIVALILLMMAIGLNLAGLFEMGTLSSGSRLQQQQGPAGDFWT
HHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHCCCCCHHHH
GVLAAFVATPCTGPFMATALGAALVLPAYVGLMVFAGLGLGMALPFLLVGFVPALRQRMP
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KPGAWMVTAKRIFAVPMLLTALGLVWVLMQQTDRQYVFVALLLAMLLGLALWLMGLLQHG
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GRERPWWPALLAVIIVAGTLLSVSPGAETQISKAGAETNRPLTFNEKDLSALIMEQDVFV
CCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCEECHHHHHHHEEECCEEE
YFSADWCLTCKVNETTAIERQDTQAAFERAGMAVMLGDWTNGDPQITEFLAKHQRSGVPL
EEECCEEEEEEECCCCCCCCHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHCCCCCE
YLWYKKGNLQPEVLPQILTSSLLIERAGG
EEEEECCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA