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The map label for this gene is htpX [H]

Identifier: 119774580

GI number: 119774580

Start: 1753224

End: 1754114

Strand: Direct

Name: htpX [H]

Synonym: Sama_1443

Alternate gene names: 119774580

Gene position: 1753224-1754114 (Clockwise)

Preceding gene: 119774578

Following gene: 119774581

Centisome position: 40.71

GC content: 53.09

Gene sequence:

>891_bases
ATGGGCGATTTGCCCGATAAAGGAGCTGAAATGAAACGTGTATTTCTTTTCCTGTTGACCAACCTGGCGGTGCTGCTGGT
TGCGTCGATAGTGATGTCTATTCTGGGCGTTGATACCCGCTCTATGAGTGGTCTGTTGGTGTTTGCGGCCATCTTTGGTT
TCGGTGGCGCCTTTTTCTCGCTGGCCATTTCCAAATGGATGGCGAAAAAGTCCATGGGTTGTGAAGTTATCACCACCCCA
CGCGATGCCACAGAAAAATGGCTGATTGATACGGTTGCCCGCCAGGCGCAGCAAGCCGGTATCAAGATGCCTGAAGTGGC
TATCTATAATTCACCTGAAATGAACGCCTTTGCCACAGGCCCCAGCAAAAACAACTCGCTGGTTGCCGTAAGTACCGGTC
TGCTCTACGGTATGACCCAGGATGAAGTGGAAGGTGTTCTGGCACACGAAGTCAGCCACGTGGCCAATGGCGACATGGTG
ACACTGACCCTTATTCAGGGCGTGGTGAACACCTTTGTTATCTTCGCCGCCCGCGTAGTCGCTGGATTTATCAATAACTT
CCTCTCCAGCGACGAAGAGGGTGAAGGTTTGGGCACCTTTGCCTATATCGCGGTGGTGTTTGTACTGGAAATGCTGTTTG
GTATTCTGGCGTCTATCGTGGTTGCTTACTTCTCCCGAATCCGTGAGTATCGTGCCGACGAAGGCGGTGCCAAGCTGGCA
GGTCGTCACAAGATGGTTGCTGCACTAGAGCGTTTGCGTAATGGTCCGGAGACCGGCGCCATGCCAGCGCAAATGGCGGC
GTTTGGTATCAATGGCAAGCGTTCACTCGGTGAGCTGCTGATGAGCCACCCGCCATTGGAAAAACGCATTCAGGCGCTCA
AAGCGCAGTAA

Upstream 100 bases:

>100_bases
TAGACTGCCGCCATATGTTCCGACAGGGGATTTGGACTTTTTCACCAGCGTACCCTTGAAAATCGAATTTTAAGACATAT
TATGTCCCTTGTGAGTGTGA

Downstream 100 bases:

>100_bases
TCAAAAAAAGAGGCCTTTGGGCCTCTTTTTTATTATCAGTGGTAGGTCGCATTTGACGAAAACGCTTTTTACGTTATGTT
AGTAAAGCGGGATAGCATGT

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MGDLPDKGAEMKRVFLFLLTNLAVLLVASIVMSILGVDTRSMSGLLVFAAIFGFGGAFFSLAISKWMAKKSMGCEVITTP
RDATEKWLIDTVARQAQQAGIKMPEVAIYNSPEMNAFATGPSKNNSLVAVSTGLLYGMTQDEVEGVLAHEVSHVANGDMV
TLTLIQGVVNTFVIFAARVVAGFINNFLSSDEEGEGLGTFAYIAVVFVLEMLFGILASIVVAYFSRIREYRADEGGAKLA
GRHKMVAALERLRNGPETGAMPAQMAAFGINGKRSLGELLMSHPPLEKRIQALKAQ

Sequences:

>Translated_296_residues
MGDLPDKGAEMKRVFLFLLTNLAVLLVASIVMSILGVDTRSMSGLLVFAAIFGFGGAFFSLAISKWMAKKSMGCEVITTP
RDATEKWLIDTVARQAQQAGIKMPEVAIYNSPEMNAFATGPSKNNSLVAVSTGLLYGMTQDEVEGVLAHEVSHVANGDMV
TLTLIQGVVNTFVIFAARVVAGFINNFLSSDEEGEGLGTFAYIAVVFVLEMLFGILASIVVAYFSRIREYRADEGGAKLA
GRHKMVAALERLRNGPETGAMPAQMAAFGINGKRSLGELLMSHPPLEKRIQALKAQ
>Mature_295_residues
GDLPDKGAEMKRVFLFLLTNLAVLLVASIVMSILGVDTRSMSGLLVFAAIFGFGGAFFSLAISKWMAKKSMGCEVITTPR
DATEKWLIDTVARQAQQAGIKMPEVAIYNSPEMNAFATGPSKNNSLVAVSTGLLYGMTQDEVEGVLAHEVSHVANGDMVT
LTLIQGVVNTFVIFAARVVAGFINNFLSSDEEGEGLGTFAYIAVVFVLEMLFGILASIVVAYFSRIREYRADEGGAKLAG
RHKMVAALERLRNGPETGAMPAQMAAFGINGKRSLGELLMSHPPLEKRIQALKAQ

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=289, Percent_Identity=57.0934256055363, Blast_Score=325, Evalue=2e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 31787; Mature: 31655

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDLPDKGAEMKRVFLFLLTNLAVLLVASIVMSILGVDTRSMSGLLVFAAIFGFGGAFFS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LAISKWMAKKSMGCEVITTPRDATEKWLIDTVARQAQQAGIKMPEVAIYNSPEMNAFATG
HHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEECC
PSKNNSLVAVSTGLLYGMTQDEVEGVLAHEVSHVANGDMVTLTLIQGVVNTFVIFAARVV
CCCCCCEEEEECCHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AGFINNFLSSDEEGEGLGTFAYIAVVFVLEMLFGILASIVVAYFSRIREYRADEGGAKLA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
GRHKMVAALERLRNGPETGAMPAQMAAFGINGKRSLGELLMSHPPLEKRIQALKAQ
HHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure 
GDLPDKGAEMKRVFLFLLTNLAVLLVASIVMSILGVDTRSMSGLLVFAAIFGFGGAFFS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LAISKWMAKKSMGCEVITTPRDATEKWLIDTVARQAQQAGIKMPEVAIYNSPEMNAFATG
HHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEECC
PSKNNSLVAVSTGLLYGMTQDEVEGVLAHEVSHVANGDMVTLTLIQGVVNTFVIFAARVV
CCCCCCEEEEECCHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AGFINNFLSSDEEGEGLGTFAYIAVVFVLEMLFGILASIVVAYFSRIREYRADEGGAKLA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
GRHKMVAALERLRNGPETGAMPAQMAAFGINGKRSLGELLMSHPPLEKRIQALKAQ
HHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA