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The map label for this gene is sucC

Identifier: 119774566

GI number: 119774566

Start: 1740653

End: 1741819

Strand: Direct

Name: sucC

Synonym: Sama_1429

Alternate gene names: 119774566

Gene position: 1740653-1741819 (Clockwise)

Preceding gene: 119774565

Following gene: 119774567

Centisome position: 40.42

GC content: 53.81

Gene sequence:

>1167_bases
ATGAACTTGCATGAGTATCAGGCAAAAGCCCTCTTTGCCGAATATGGTTTACCAGTGTCAGAAGGCTATGCCTGCGATAC
CCCTCAAGAAGCGGTAGAAGCGGCCGGTCGTATTGGCGGAAATATGTGGGTAGTCAAGTGTCAGGTGCACGCTGGCGGCC
GCGGTAAGGCTGGTGGCGTTAAAGTGACTGGCGACAAAGAAGAAATCCGCGCCTTCGCTGAAAAGTGGCTGGGCAAGAAC
CTGGTGACTTACCAGACTGACGAAAACGGTCAGCCAGTTGCCAAGATCCTGGTTGAAAGCTGCACCGACATTGCCAACGA
ACTGTACCTGGGTGCCGTAGTTGACCGCGCTACCCGTCGCGTAGTGTTCATGGCTTCTACCGAAGGTGGTGTGGAAATCG
AAAAAGTGGCTGAAGAGACTCCTGAGCTCATTCACAAAGCCATCATCGATCCTATCGCCGGTCCACAGCCTTTCCAGGCT
CGTGACCTTGGCTTCAAGCTGGGTCTGAACCCAACTCAAATGAAGCAGTTCACCAAGATATTCATGGGCCTGGCCCAGAT
GTTCCTGGATCACGACTTCGCTCTGCTGGAAATCAACCCACTGGTAATCACTACCGAGGGTAACCTGCACTGCCTGGACG
GCAAGATTGGTGTAGATGGTAACGCTCTGTTCCGTCAGCCAAAAATCAAAGACATGCACGATCCTTCTCAGGATGACGCC
CGTGAAGCCCACGCTGCCAAGTTCGAACTGAACTACGTAGCTCTGGACGGTAACGTAGGCTGCATGGTGAACGGTGCTGG
TCTCGCCATGGGTACCATGGACATCGTAAACCTGCACGGCGGTAAGCCAGCCAACTTCCTCGACGTAGGTGGCGGCGCGA
CCAAAGAGCGCGTTTCCGAAGCGTTCAAGATCATTCTGTCTGACAGCAATGTGAAAGCCGTTCTGGTTAACATCTTCGGT
GGTATCGTGCGTTGTGACATGATCGCCGAAGGTATCATCGGTGCGGTGAAAGAAGTAGGCGTGAAGGTGCCTGTAGTTGT
GCGTCTGGAAGGTACCAACGCTGAACTGGGTGCCAAGGTGCTGGCTGAATCTGGTCTGGACATCATTGCTGCCAAGAGCC
TGACCGACGCTGCTCAGCAAGTTGTTAAAGCTGCGGAGGGCAAGTAA

Upstream 100 bases:

>100_bases
CCCGTCTGCTGCTGGACATCTAATCAGCACAGACAAAAAACCTCGTGACTGGCCCCTCGGGGCCAGTTGGATTTAAAACG
TAGTATACGGATAGATCATC

Downstream 100 bases:

>100_bases
TGTCTGTATTGATCAACAAAGATACCAAGGTAATCTGCCAAGGTTTTACCGGTGGTCAGGGCACTTTCCACTCTGAGCAG
GCTATCGCTTACGGTACTCA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQAKALFAEYGLPVSEGYACDTPQEAVEAAGRIGGNMWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEKWLGKN
LVTYQTDENGQPVAKILVESCTDIANELYLGAVVDRATRRVVFMASTEGGVEIEKVAEETPELIHKAIIDPIAGPQPFQA
RDLGFKLGLNPTQMKQFTKIFMGLAQMFLDHDFALLEINPLVITTEGNLHCLDGKIGVDGNALFRQPKIKDMHDPSQDDA
REAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVSEAFKIILSDSNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGAKVLAESGLDIIAAKSLTDAAQQVVKAAEGK

Sequences:

>Translated_388_residues
MNLHEYQAKALFAEYGLPVSEGYACDTPQEAVEAAGRIGGNMWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEKWLGKN
LVTYQTDENGQPVAKILVESCTDIANELYLGAVVDRATRRVVFMASTEGGVEIEKVAEETPELIHKAIIDPIAGPQPFQA
RDLGFKLGLNPTQMKQFTKIFMGLAQMFLDHDFALLEINPLVITTEGNLHCLDGKIGVDGNALFRQPKIKDMHDPSQDDA
REAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVSEAFKIILSDSNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGAKVLAESGLDIIAAKSLTDAAQQVVKAAEGK
>Mature_388_residues
MNLHEYQAKALFAEYGLPVSEGYACDTPQEAVEAAGRIGGNMWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEKWLGKN
LVTYQTDENGQPVAKILVESCTDIANELYLGAVVDRATRRVVFMASTEGGVEIEKVAEETPELIHKAIIDPIAGPQPFQA
RDLGFKLGLNPTQMKQFTKIFMGLAQMFLDHDFALLEINPLVITTEGNLHCLDGKIGVDGNALFRQPKIKDMHDPSQDDA
REAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVSEAFKIILSDSNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGAKVLAESGLDIIAAKSLTDAAQQVVKAAEGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=46.5648854961832, Blast_Score=346, Evalue=2e-95,
Organism=Homo sapiens, GI157779135, Length=387, Percent_Identity=45.4780361757106, Blast_Score=316, Evalue=2e-86,
Organism=Homo sapiens, GI294862256, Length=366, Percent_Identity=45.6284153005465, Blast_Score=300, Evalue=1e-81,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=78.3505154639175, Blast_Score=605, Evalue=1e-174,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=44.7300771208226, Blast_Score=316, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI17539378, Length=400, Percent_Identity=41.5, Blast_Score=299, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=42.4242424242424, Blast_Score=328, Evalue=1e-90,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=42.5692695214106, Blast_Score=292, Evalue=3e-79,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=41.9847328244275, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=41.9847328244275, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=42.1319796954315, Blast_Score=285, Evalue=5e-77,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=42.1319796954315, Blast_Score=285, Evalue=5e-77,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_SHEAM (A1S5I0)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927306.1
- ProteinModelPortal:   A1S5I0
- SMR:   A1S5I0
- STRING:   A1S5I0
- GeneID:   4603681
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1429
- NMPDR:   fig|326297.7.peg.1347
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   EGDIGCM
- PhylomeDB:   A1S5I0
- ProtClustDB:   PRK00696
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41354; Mature: 41354

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKALFAEYGLPVSEGYACDTPQEAVEAAGRIGGNMWVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
KVTGDKEEIRAFAEKWLGKNLVTYQTDENGQPVAKILVESCTDIANELYLGAVVDRATRR
EEECCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VVFMASTEGGVEIEKVAEETPELIHKAIIDPIAGPQPFQARDLGFKLGLNPTQMKQFTKI
EEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCEEECCCHHHHHHHHHH
FMGLAQMFLDHDFALLEINPLVITTEGNLHCLDGKIGVDGNALFRQPKIKDMHDPSQDDA
HHHHHHHHHCCCEEEEEEEEEEEEECCCEEEECCEECCCCCHHCCCCCCCCCCCCCCHHH
REAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVSE
HHHHHEEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDSNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGAKV
HHEEEECCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHH
LAESGLDIIAAKSLTDAAQQVVKAAEGK
HHHCCCCEEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLHEYQAKALFAEYGLPVSEGYACDTPQEAVEAAGRIGGNMWVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
KVTGDKEEIRAFAEKWLGKNLVTYQTDENGQPVAKILVESCTDIANELYLGAVVDRATRR
EEECCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VVFMASTEGGVEIEKVAEETPELIHKAIIDPIAGPQPFQARDLGFKLGLNPTQMKQFTKI
EEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCEEECCCHHHHHHHHHH
FMGLAQMFLDHDFALLEINPLVITTEGNLHCLDGKIGVDGNALFRQPKIKDMHDPSQDDA
HHHHHHHHHCCCEEEEEEEEEEEEECCCEEEECCEECCCCCHHCCCCCCCCCCCCCCHHH
REAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVSE
HHHHHEEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDSNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGAKV
HHEEEECCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHH
LAESGLDIIAAKSLTDAAQQVVKAAEGK
HHHCCCCEEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA