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The map label for this gene is atoB [H]

Identifier: 119774512

GI number: 119774512

Start: 1665719

End: 1666897

Strand: Direct

Name: atoB [H]

Synonym: Sama_1375

Alternate gene names: 119774512

Gene position: 1665719-1666897 (Clockwise)

Preceding gene: 119774511

Following gene: 119774513

Centisome position: 38.68

GC content: 61.15

Gene sequence:

>1179_bases
ATGAGCGTATCGGATATCGTCATTGTTGCGGCAAAACGCACCGCCATGGGTGGTTTTCAGGGCAGCCTGTCTGAGGTGCC
GTCACCCAAGTTGGCCGCGACTGCAGTCAAGGCTCTGCTGGATGACACAGGCCTGGATGGCGCCAGGGTTGACGAACTCC
TGATGGGCTGCGTGCTGCCTGCAGGTCTTGGCCAGGCGCCAGCCCGTCAGGCTGCACTGGGCGCAGGTTTGCCGCTGTCA
GTGGGCGCCACCACGGTCAACAAGGTGTGTGGCTCAGGCATGAAAACCGTGATGCTGGCCCATGACCTCATCAAAGCAGG
CAGCGCCAAGGTGGTGATTGCCGGCGGCATGGAGAGCATGAGCCAGGCCCCATACCTGCTCGATAAAGCCCGCGGCGGTA
TGCGCATGGGCCACGGCAAGGTGCTTGACCACATGTTCCTCGACGGTCTTGAAGATGCCTACACCGGCGGCGCCATGGGC
ACCTTCGCCCAGAAAACGGCTGACGATTACGGCCTGACCCGCGAGTCCATGGACGCATTCGCCTTAAGCTCTCTGGAAAA
AGCCAATGCGGCGATCAATTCCGGCGCCTTCGAAGCGGAAATCGTGCCTGTAACCGTGTCCAGCCGCAAAGGCGATGTGG
AAGTGAAAGTTGATGAGCAGCCCGGTAATGCCCGTCCCGAGAAGATTCCGACGCTGCGCCCGGCCTTTGCCAAAGACGGC
ACCATCACTGCCGCCAACTCATCGTCTATCTCCGACGGTGCAGCTGCGCTGATGCTGATGAGCCGCGATCAGGCCGACGC
TCTGGGTCTTAAGGTACTGGCCACCATCAAGGGGCACACTACCCATGCCCAGGAGCCAGCCATGTTCACCACAGCCCCAG
TGGGAGCCATGACCAAGCTGCTCTCCAATGTGGGCTGGAGCAAGGACGAGGTTGATCTCTTTGAAATCAATGAAGCCTTT
GCCATGGTGACCATGCTTGCCATCAGTGAGCTCAAGCTGGATGCGGCCAGAGTTAACGTGAACGGCGGCGCCTGCGCCCT
GGGTCACCCCATAGGCTGCTCCGGCGCCCGAGTGCTGGTGACCCTCATCCATGCGCTCAAGGCCCGAGGCCTGAAGCGCG
GCGTGGCCTCTCTGTGTATCGGCGGCGGCGAAGCCACAGCCATGGCCATCGAAGTTTAA

Upstream 100 bases:

>100_bases
GCGTAAACGTCACATTCAATGCATCGGGTCGCAAACCGCGACCGCCATCACATTTGCACCGGGTTTTGGCCCCGGGCATC
ACAAGCAATTGGAGTGAGAA

Downstream 100 bases:

>100_bases
TTGCCAGGACACGGCAAACTGCAATCAACAAGACACTCGACAGAAGCGCAGGCGCGGCCATACACAATACCTACAAGGCT
GCGCTGCCAACTCTGACCCT

Product: Acetyl-CoA C-acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSVSDIVIVAAKRTAMGGFQGSLSEVPSPKLAATAVKALLDDTGLDGARVDELLMGCVLPAGLGQAPARQAALGAGLPLS
VGATTVNKVCGSGMKTVMLAHDLIKAGSAKVVIAGGMESMSQAPYLLDKARGGMRMGHGKVLDHMFLDGLEDAYTGGAMG
TFAQKTADDYGLTRESMDAFALSSLEKANAAINSGAFEAEIVPVTVSSRKGDVEVKVDEQPGNARPEKIPTLRPAFAKDG
TITAANSSSISDGAAALMLMSRDQADALGLKVLATIKGHTTHAQEPAMFTTAPVGAMTKLLSNVGWSKDEVDLFEINEAF
AMVTMLAISELKLDAARVNVNGGACALGHPIGCSGARVLVTLIHALKARGLKRGVASLCIGGGEATAMAIEV

Sequences:

>Translated_392_residues
MSVSDIVIVAAKRTAMGGFQGSLSEVPSPKLAATAVKALLDDTGLDGARVDELLMGCVLPAGLGQAPARQAALGAGLPLS
VGATTVNKVCGSGMKTVMLAHDLIKAGSAKVVIAGGMESMSQAPYLLDKARGGMRMGHGKVLDHMFLDGLEDAYTGGAMG
TFAQKTADDYGLTRESMDAFALSSLEKANAAINSGAFEAEIVPVTVSSRKGDVEVKVDEQPGNARPEKIPTLRPAFAKDG
TITAANSSSISDGAAALMLMSRDQADALGLKVLATIKGHTTHAQEPAMFTTAPVGAMTKLLSNVGWSKDEVDLFEINEAF
AMVTMLAISELKLDAARVNVNGGACALGHPIGCSGARVLVTLIHALKARGLKRGVASLCIGGGEATAMAIEV
>Mature_391_residues
SVSDIVIVAAKRTAMGGFQGSLSEVPSPKLAATAVKALLDDTGLDGARVDELLMGCVLPAGLGQAPARQAALGAGLPLSV
GATTVNKVCGSGMKTVMLAHDLIKAGSAKVVIAGGMESMSQAPYLLDKARGGMRMGHGKVLDHMFLDGLEDAYTGGAMGT
FAQKTADDYGLTRESMDAFALSSLEKANAAINSGAFEAEIVPVTVSSRKGDVEVKVDEQPGNARPEKIPTLRPAFAKDGT
ITAANSSSISDGAAALMLMSRDQADALGLKVLATIKGHTTHAQEPAMFTTAPVGAMTKLLSNVGWSKDEVDLFEINEAFA
MVTMLAISELKLDAARVNVNGGACALGHPIGCSGARVLVTLIHALKARGLKRGVASLCIGGGEATAMAIEV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=389, Percent_Identity=44.7300771208226, Blast_Score=323, Evalue=2e-88,
Organism=Homo sapiens, GI4557237, Length=392, Percent_Identity=45.1530612244898, Blast_Score=322, Evalue=6e-88,
Organism=Homo sapiens, GI167614485, Length=391, Percent_Identity=37.3401534526854, Blast_Score=249, Evalue=4e-66,
Organism=Homo sapiens, GI4501853, Length=409, Percent_Identity=36.4303178484108, Blast_Score=222, Evalue=4e-58,
Organism=Homo sapiens, GI4504327, Length=425, Percent_Identity=28.7058823529412, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI194353979, Length=91, Percent_Identity=47.2527472527472, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI87082165, Length=388, Percent_Identity=47.9381443298969, Blast_Score=350, Evalue=1e-97,
Organism=Escherichia coli, GI1788554, Length=391, Percent_Identity=51.9181585677749, Blast_Score=343, Evalue=9e-96,
Organism=Escherichia coli, GI1787663, Length=393, Percent_Identity=38.4223918575064, Blast_Score=224, Evalue=6e-60,
Organism=Escherichia coli, GI48994986, Length=405, Percent_Identity=37.5308641975309, Blast_Score=207, Evalue=8e-55,
Organism=Escherichia coli, GI1788683, Length=402, Percent_Identity=28.3582089552239, Blast_Score=136, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI25147385, Length=384, Percent_Identity=43.75, Blast_Score=303, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI17535921, Length=393, Percent_Identity=40.7124681933842, Blast_Score=281, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI133906874, Length=387, Percent_Identity=37.7260981912145, Blast_Score=264, Evalue=6e-71,
Organism=Caenorhabditis elegans, GI17535917, Length=395, Percent_Identity=34.9367088607595, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17551802, Length=426, Percent_Identity=29.3427230046948, Blast_Score=158, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6325229, Length=394, Percent_Identity=48.2233502538071, Blast_Score=334, Evalue=1e-92,
Organism=Saccharomyces cerevisiae, GI6322031, Length=387, Percent_Identity=34.3669250645995, Blast_Score=197, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24655093, Length=390, Percent_Identity=46.6666666666667, Blast_Score=350, Evalue=1e-96,
Organism=Drosophila melanogaster, GI24640423, Length=391, Percent_Identity=43.2225063938619, Blast_Score=300, Evalue=1e-81,
Organism=Drosophila melanogaster, GI17648125, Length=395, Percent_Identity=38.2278481012658, Blast_Score=251, Evalue=4e-67,
Organism=Drosophila melanogaster, GI17137578, Length=424, Percent_Identity=30.6603773584906, Blast_Score=151, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 40107; Mature: 39976

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00098 THIOLASE_1 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSDIVIVAAKRTAMGGFQGSLSEVPSPKLAATAVKALLDDTGLDGARVDELLMGCVLP
CCCCCEEEEEECHHHCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
AGLGQAPARQAALGAGLPLSVGATTVNKVCGSGMKTVMLAHDLIKAGSAKVVIAGGMESM
CCCCCCCHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCHHHH
SQAPYLLDKARGGMRMGHGKVLDHMFLDGLEDAYTGGAMGTFAQKTADDYGLTRESMDAF
HCCCHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHH
ALSSLEKANAAINSGAFEAEIVPVTVSSRKGDVEVKVDEQPGNARPEKIPTLRPAFAKDG
HHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
TITAANSSSISDGAAALMLMSRDQADALGLKVLATIKGHTTHAQEPAMFTTAPVGAMTKL
EEEECCCCCCCCHHHEEEEEECCCCHHHCEEEEEEECCCCCCCCCCCEEEECCHHHHHHH
LSNVGWSKDEVDLFEINEAFAMVTMLAISELKLDAARVNVNGGACALGHPIGCSGARVLV
HHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHEEEEEEEECCCCEEECCCCCCCCHHHHHH
TLIHALKARGLKRGVASLCIGGGEATAMAIEV
HHHHHHHHHHHHHHHHHHEECCCCEEEEEEEC
>Mature Secondary Structure 
SVSDIVIVAAKRTAMGGFQGSLSEVPSPKLAATAVKALLDDTGLDGARVDELLMGCVLP
CCCCEEEEEECHHHCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
AGLGQAPARQAALGAGLPLSVGATTVNKVCGSGMKTVMLAHDLIKAGSAKVVIAGGMESM
CCCCCCCHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCHHHH
SQAPYLLDKARGGMRMGHGKVLDHMFLDGLEDAYTGGAMGTFAQKTADDYGLTRESMDAF
HCCCHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHH
ALSSLEKANAAINSGAFEAEIVPVTVSSRKGDVEVKVDEQPGNARPEKIPTLRPAFAKDG
HHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
TITAANSSSISDGAAALMLMSRDQADALGLKVLATIKGHTTHAQEPAMFTTAPVGAMTKL
EEEECCCCCCCCHHHEEEEEECCCCHHHCEEEEEEECCCCCCCCCCCEEEECCHHHHHHH
LSNVGWSKDEVDLFEINEAFAMVTMLAISELKLDAARVNVNGGACALGHPIGCSGARVLV
HHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHEEEEEEEECCCCEEECCCCCCCCHHHHHH
TLIHALKARGLKRGVASLCIGGGEATAMAIEV
HHHHHHHHHHHHHHHHHHEECCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]