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The map label for this gene is yqjI [H]

Identifier: 119774502

GI number: 119774502

Start: 1656305

End: 1657840

Strand: Direct

Name: yqjI [H]

Synonym: Sama_1365

Alternate gene names: 119774502

Gene position: 1656305-1657840 (Clockwise)

Preceding gene: 119774501

Following gene: 119774504

Centisome position: 38.46

GC content: 58.2

Gene sequence:

>1536_bases
ATGCAAAACCACACCCAATTACACGACATCGGGGTTATCGGCCTGGGTGTCATGGGCAAAAACCTTGCCCTCAATATCGC
AGACAATGGCTATCGTGTGGCCGCCTTTGACCTCGACGGTGCCAAGGTGCGCGCCGCCGTCAGCCAATCGCAGGCCGAAG
TTGCCGCCAAACCTGCACACAGTAAGGCCACGCAGCTGACAGGTGTGGACAGTCTCAAGTCCATGCTCTGCGCCTTGACC
TCACCCAGACTCCTGTTGCTGTCGGTACCTGCCGGTGCGCCGGTAGACGGCGTTTGCTCGGCCCTTATTGATGCCGGTAT
CAAGCCTGATGACATCGTTATCGACACCGGCAACAGCCTGTGGACCGATACTGTAAAGCGCGAGCAGGAGTACGCCGGCA
AGTTTGTGTTTTTCTCTTCTGCCGTTTCCGGCGGCGAAGTAGGCGCCCGTTTTGGCCCTTCACTGATGCCATCGGGTAAA
AAAGAAGCCTGGGACAGTGTGGCCCCCATCTGGCGCGCCATTGCCGCCAAGGTGGACAACACCACAGGTTTGCCCATTGA
GCGCTTTGAGCCGGGTAACCCTGTACTGGAAGGCGAGCCCTGCACTGCGTACATAGGTCCGGCTGGCAGTGGCCACTACG
TAAAAATGGTGCACAACGGTATCGAATATGCCGACATGCAGCTGATTTGCGAAGCCTATCAGTTGCTCTCTGATGTGCTT
GGGCTGTCGGCGGTGGAGATAGCGGCTATTTTTGAACGCTGGAACCGCGGCAAACTCAACAGCTACCTGATGGGTATAAG
CGCCGAAGTGCTGCGTCAGAGCGATCCCCTCACCGGCAAGCCGCTGGTGGAAATGATTCTGGATAAGGCCGGGCAGAAGG
GCACGGGTTTGTGGACTGCGGTCAGCAGCCTGCAAATTGGCACCCCGGCGCCAACGATTGCGGAGGCTGTTTACGCCCGG
GCGTTGTCAAATCAAAAGGCGCTTCGTACCGAGTTGGCAGGCCGTCTGGCCGGCGCTATGCCGTTGCAGGGCATAGATGC
GACAAGCTTTATCGATGAGCTGGAGCAGGCACTCTTTTGCGCGAAAATTTGCTGTTATGCCCAGGGTTTCCAGTTGATGG
CCATGAACGCCGCCGAACAGGGATGGGAGCTGGACTTTGCCGCCATCGCCCGCATCTGGCGTGCCGGTTGTATCATTCGG
GCCACCTTCCTGCAGTCCATTACTGATGCCTTTGAGGCCGAGCCCAAACTCGCCAATCTGCTGATAGCGAAAAGCTTTGC
CGAGGCGCTGAGTGAGGCCCAGCAATCCTGGCGCCACCTGGTGTCCAAGGCCGTCCTTGCGGGGGTGCCTGCACCTTGTA
TTACCTCGGCGCTGGCATATTACGACGGCTATCGCCGCGAAACCCTGCCCGCCAACTTGTTGCAGGGTCAGCGCGATTAC
TTTGGTGCCCACAGCTTTGAGCGTATCGATACGCAGGCGGGTGAAAAATACCACCTCAACTGGAGCAGTCCGGCGCGTGA
GTTGCAAAAGCTCTGA

Upstream 100 bases:

>100_bases
GCAATCCTATGCATTATCTTGCATTACTGTAATTCAGTTACCAAAATCGCTATAATCCGCCGCGAAATTTGGCTCTTCCT
GTACCCGTGGAATAAAAAGC

Downstream 100 bases:

>100_bases
AGTGTAATAGCGCTGAACTGCAATAGCTCTGAACTGTAAAAGCGCTGAACTGTAAACGCTGTGAGCGGCTGACGCTACGC
GCTTCACACCAGTAAATAAA

Product: 6-phosphogluconate dehydrogenase

Products: NA

Alternate protein names: GNTZII [H]

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MQNHTQLHDIGVIGLGVMGKNLALNIADNGYRVAAFDLDGAKVRAAVSQSQAEVAAKPAHSKATQLTGVDSLKSMLCALT
SPRLLLLSVPAGAPVDGVCSALIDAGIKPDDIVIDTGNSLWTDTVKREQEYAGKFVFFSSAVSGGEVGARFGPSLMPSGK
KEAWDSVAPIWRAIAAKVDNTTGLPIERFEPGNPVLEGEPCTAYIGPAGSGHYVKMVHNGIEYADMQLICEAYQLLSDVL
GLSAVEIAAIFERWNRGKLNSYLMGISAEVLRQSDPLTGKPLVEMILDKAGQKGTGLWTAVSSLQIGTPAPTIAEAVYAR
ALSNQKALRTELAGRLAGAMPLQGIDATSFIDELEQALFCAKICCYAQGFQLMAMNAAEQGWELDFAAIARIWRAGCIIR
ATFLQSITDAFEAEPKLANLLIAKSFAEALSEAQQSWRHLVSKAVLAGVPAPCITSALAYYDGYRRETLPANLLQGQRDY
FGAHSFERIDTQAGEKYHLNWSSPARELQKL

Sequences:

>Translated_511_residues
MQNHTQLHDIGVIGLGVMGKNLALNIADNGYRVAAFDLDGAKVRAAVSQSQAEVAAKPAHSKATQLTGVDSLKSMLCALT
SPRLLLLSVPAGAPVDGVCSALIDAGIKPDDIVIDTGNSLWTDTVKREQEYAGKFVFFSSAVSGGEVGARFGPSLMPSGK
KEAWDSVAPIWRAIAAKVDNTTGLPIERFEPGNPVLEGEPCTAYIGPAGSGHYVKMVHNGIEYADMQLICEAYQLLSDVL
GLSAVEIAAIFERWNRGKLNSYLMGISAEVLRQSDPLTGKPLVEMILDKAGQKGTGLWTAVSSLQIGTPAPTIAEAVYAR
ALSNQKALRTELAGRLAGAMPLQGIDATSFIDELEQALFCAKICCYAQGFQLMAMNAAEQGWELDFAAIARIWRAGCIIR
ATFLQSITDAFEAEPKLANLLIAKSFAEALSEAQQSWRHLVSKAVLAGVPAPCITSALAYYDGYRRETLPANLLQGQRDY
FGAHSFERIDTQAGEKYHLNWSSPARELQKL
>Mature_511_residues
MQNHTQLHDIGVIGLGVMGKNLALNIADNGYRVAAFDLDGAKVRAAVSQSQAEVAAKPAHSKATQLTGVDSLKSMLCALT
SPRLLLLSVPAGAPVDGVCSALIDAGIKPDDIVIDTGNSLWTDTVKREQEYAGKFVFFSSAVSGGEVGARFGPSLMPSGK
KEAWDSVAPIWRAIAAKVDNTTGLPIERFEPGNPVLEGEPCTAYIGPAGSGHYVKMVHNGIEYADMQLICEAYQLLSDVL
GLSAVEIAAIFERWNRGKLNSYLMGISAEVLRQSDPLTGKPLVEMILDKAGQKGTGLWTAVSSLQIGTPAPTIAEAVYAR
ALSNQKALRTELAGRLAGAMPLQGIDATSFIDELEQALFCAKICCYAQGFQLMAMNAAEQGWELDFAAIARIWRAGCIIR
ATFLQSITDAFEAEPKLANLLIAKSFAEALSEAQQSWRHLVSKAVLAGVPAPCITSALAYYDGYRRETLPANLLQGQRDY
FGAHSFERIDTQAGEKYHLNWSSPARELQKL

Specific function: Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH [H]

COG id: COG0362

COG function: function code G; 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=496, Percent_Identity=45.1612903225806, Blast_Score=428, Evalue=1e-120,
Organism=Escherichia coli, GI1788341, Length=498, Percent_Identity=43.3734939759036, Blast_Score=409, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17542558, Length=502, Percent_Identity=43.6254980079681, Blast_Score=407, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6321695, Length=503, Percent_Identity=45.1292246520875, Blast_Score=432, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6321977, Length=503, Percent_Identity=44.1351888667992, Blast_Score=421, Evalue=1e-118,
Organism=Drosophila melanogaster, GI24639279, Length=497, Percent_Identity=45.271629778672, Blast_Score=409, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR006114
- InterPro:   IPR006113
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR012284
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: =1.1.1.44 [H]

Molecular weight: Translated: 54849; Mature: 54849

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00461 6PGD ; PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNHTQLHDIGVIGLGVMGKNLALNIADNGYRVAAFDLDGAKVRAAVSQSQAEVAAKPAH
CCCCCCHHHCCEEEECCCCCCEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCC
SKATQLTGVDSLKSMLCALTSPRLLLLSVPAGAPVDGVCSALIDAGIKPDDIVIDTGNSL
CHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEECCCCH
WTDTVKREQEYAGKFVFFSSAVSGGEVGARFGPSLMPSGKKEAWDSVAPIWRAIAAKVDN
HHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
TTGLPIERFEPGNPVLEGEPCTAYIGPAGSGHYVKMVHNGIEYADMQLICEAYQLLSDVL
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHHHH
GLSAVEIAAIFERWNRGKLNSYLMGISAEVLRQSDPLTGKPLVEMILDKAGQKGTGLWTA
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHH
VSSLQIGTPAPTIAEAVYARALSNQKALRTELAGRLAGAMPLQGIDATSFIDELEQALFC
HHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
AKICCYAQGFQLMAMNAAEQGWELDFAAIARIWRAGCIIRATFLQSITDAFEAEPKLANL
HHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LIAKSFAEALSEAQQSWRHLVSKAVLAGVPAPCITSALAYYDGYRRETLPANLLQGQRDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCHHH
FGAHSFERIDTQAGEKYHLNWSSPARELQKL
CCCCHHHHHHHCCCCEEEECCCCHHHHHHCC
>Mature Secondary Structure
MQNHTQLHDIGVIGLGVMGKNLALNIADNGYRVAAFDLDGAKVRAAVSQSQAEVAAKPAH
CCCCCCHHHCCEEEECCCCCCEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCC
SKATQLTGVDSLKSMLCALTSPRLLLLSVPAGAPVDGVCSALIDAGIKPDDIVIDTGNSL
CHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEECCCCH
WTDTVKREQEYAGKFVFFSSAVSGGEVGARFGPSLMPSGKKEAWDSVAPIWRAIAAKVDN
HHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
TTGLPIERFEPGNPVLEGEPCTAYIGPAGSGHYVKMVHNGIEYADMQLICEAYQLLSDVL
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHHHH
GLSAVEIAAIFERWNRGKLNSYLMGISAEVLRQSDPLTGKPLVEMILDKAGQKGTGLWTA
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHH
VSSLQIGTPAPTIAEAVYARALSNQKALRTELAGRLAGAMPLQGIDATSFIDELEQALFC
HHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
AKICCYAQGFQLMAMNAAEQGWELDFAAIARIWRAGCIIRATFLQSITDAFEAEPKLANL
HHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LIAKSFAEALSEAQQSWRHLVSKAVLAGVPAPCITSALAYYDGYRRETLPANLLQGQRDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCHHH
FGAHSFERIDTQAGEKYHLNWSSPARELQKL
CCCCHHHHHHHCCCCEEEECCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10568751; 9298659 [H]