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The map label for this gene is htpG

Identifier: 119774450

GI number: 119774450

Start: 1596151

End: 1598064

Strand: Direct

Name: htpG

Synonym: Sama_1313

Alternate gene names: 119774450

Gene position: 1596151-1598064 (Clockwise)

Preceding gene: 119774449

Following gene: 119774451

Centisome position: 37.07

GC content: 54.91

Gene sequence:

>1914_bases
ATGTCGCATCAAGAAACCCATGGTTTTCAAACAGAAGTCAAACAGCTTTTGCATTTGATGATCCACTCTTTGTACTCCAA
CAAAGAAATCTTTTTGCGTGAACTGGTCTCCAATGCCGCCGACGCCGCTGACAAGCTGCGTTACCTGGCGCTGACCAACG
ACAGCCTGTATGAGGGTGACGGTGAGCTGCGGGTACGTGTGAGTGCCGATAAAGACAAGGGCACAGTGACCATAGAAGAC
AATGGCATTGGTATGACCCGCGATGGCGTTATCGAACACCTGGGCACCATCGCCAAATCGGGTACTGCCGAGTTCTTTAA
AAACCTCTCCGGCGACAGCGCCAAAGACTCGCAGCTGATTGGTCAGTTCGGTGTGGGTTTCTATTCGGCCTTTATCGTCG
CCAAGCGCGTTGAGGTGTTTACCCGCGCCGCCGGTCATAGCGCCGACGAAGGGGTGAAGTGGGAGTCGGAAGGTGAAGGT
AACTTCAGCGTCGAAACCATCACCAAAGCTGAGCGCGGCACCAAAATCGTGCTGCACCTGCGTGATGAAGAAAAGGAATT
TGCCGATGACTGGCGCCTGCGTTCCATCATCACCAAGTACTCAGATCATATCTCCATCCCGGTAGAGATGTATCAGGAAG
GCACCCCTGAGCGTGACGGTCCCGATGGCGAGAAGATTCCTGCCACCGAAGGTCAGTGGAAGGCTATGAACAAGGCCACC
GCCCTGTGGACCCGCAGCAAGTCAGACGTGAGCGACGAAGAGTACAAAGAATTCTACAAGCACATTTCCCACGACTTTGC
TGATCCTCTGGATTGGAGCCACAACAAGGTTGAAGGTAATCAGGAATATACCAGCCTGCTGTATATCCCGGCCAAGGCCC
CCTGGGACCTGTGGAACCGTGACCGCAAGCATGGGCTGAAGCTGTTTGTGCAGCGGGTGTTCATCATGGATGACGCTGAG
CAGTTTATGCCATCTTACCTGCGTTTCGTGCAGGGCTTGATTGACTCCAACGACTTGCCGCTGAACGTGAGCCGCGAAAT
CCTGCAGGACAATAAAGTCACGCGCAATCTGCGTCAGGCATTGACCAAGCGTGTGCTGTCGATGCTGGAAAAGCTGGCCA
AAGACGATGCCGACAAGTATCAGCAGTTCTGGGCAGAGTTTGGTACCGTGCTCAAAGAAGGTCCGGCGGAAGATTTTGCC
AACCGTGAGCGTATTGCCGGTTTGCTGCGTTTTGCCTCAACCCACACGGGTGATGCGACGCCGTCAGTGTCGCTGGATGA
TTACATCGGCCGCATGAAGGAAGGTCAGGAAAAGATTTACTACATAGTGGCCGACAGCCACGAGGCCGCGGCCAACAGCC
CACACCTGGAGCTGTTGAAGAAGAAGGGCATCGAAGTGCTGCTGCTGTCTGAGCGCATCGACGAGTGGCTGATTAACCAC
CTGCACGACTATAAAGAAAAGGCTCTGCACTCTGTGACCCGCGGCGATCTGGATCTCGGCGCCCTAGAAGACGAGGCCGA
GAAGGCCGCGCAGGAGAAATTGGCCCAGGAGTCTGAGCCCTTGGTAGAGCGATTCAAGTCTGCTCTGGGTGATAAAGTCA
GCGACGTGAAAATCACGACCCGTCTGACCGATACGCCCGCCTGTGTGGTGACAGGGGAAGGCGAAATGTCGAGCCAGATG
ATCAAGCTGATGCAGGCCGCTGGTCAACCAGTACCTGAATCCAAGCCAACGCTTGAACTTAACCCAACACACCCGCTGGT
GGCCCGTTTGGATAAGGAGCAGGATGAAACAGCCTTCGCCGAGTGGGCTGAAATGCTGCTCGCACAGGCGACCCTGTCTG
AGCGTGGCAGCCTGGCAGACCCATCTGCCTTCATCAAGCTGGTGAACCAGATGCTGCTTAAATCGGTTGGCTAA

Upstream 100 bases:

>100_bases
TCCCCTTGAAAAGTGTTTCATCGCCCCCATTTCTGTTCTATCCGGGCAGTATGCCCCAATACCTGAATGTTTTTGTAACA
CTGAAAAAAAGGGAACTGAG

Downstream 100 bases:

>100_bases
ACTGATTGCGGGGGCGAATGCCCCCGTTTGTCTTTTTGATAATGGCTTTTTACATTCAGGGGAAGCACCTATGACTCAAG
GGATACCTCAACAGGAAAGT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MSHQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDSLYEGDGELRVRVSADKDKGTVTIED
NGIGMTRDGVIEHLGTIAKSGTAEFFKNLSGDSAKDSQLIGQFGVGFYSAFIVAKRVEVFTRAAGHSADEGVKWESEGEG
NFSVETITKAERGTKIVLHLRDEEKEFADDWRLRSIITKYSDHISIPVEMYQEGTPERDGPDGEKIPATEGQWKAMNKAT
ALWTRSKSDVSDEEYKEFYKHISHDFADPLDWSHNKVEGNQEYTSLLYIPAKAPWDLWNRDRKHGLKLFVQRVFIMDDAE
QFMPSYLRFVQGLIDSNDLPLNVSREILQDNKVTRNLRQALTKRVLSMLEKLAKDDADKYQQFWAEFGTVLKEGPAEDFA
NRERIAGLLRFASTHTGDATPSVSLDDYIGRMKEGQEKIYYIVADSHEAAANSPHLELLKKKGIEVLLLSERIDEWLINH
LHDYKEKALHSVTRGDLDLGALEDEAEKAAQEKLAQESEPLVERFKSALGDKVSDVKITTRLTDTPACVVTGEGEMSSQM
IKLMQAAGQPVPESKPTLELNPTHPLVARLDKEQDETAFAEWAEMLLAQATLSERGSLADPSAFIKLVNQMLLKSVG

Sequences:

>Translated_637_residues
MSHQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDSLYEGDGELRVRVSADKDKGTVTIED
NGIGMTRDGVIEHLGTIAKSGTAEFFKNLSGDSAKDSQLIGQFGVGFYSAFIVAKRVEVFTRAAGHSADEGVKWESEGEG
NFSVETITKAERGTKIVLHLRDEEKEFADDWRLRSIITKYSDHISIPVEMYQEGTPERDGPDGEKIPATEGQWKAMNKAT
ALWTRSKSDVSDEEYKEFYKHISHDFADPLDWSHNKVEGNQEYTSLLYIPAKAPWDLWNRDRKHGLKLFVQRVFIMDDAE
QFMPSYLRFVQGLIDSNDLPLNVSREILQDNKVTRNLRQALTKRVLSMLEKLAKDDADKYQQFWAEFGTVLKEGPAEDFA
NRERIAGLLRFASTHTGDATPSVSLDDYIGRMKEGQEKIYYIVADSHEAAANSPHLELLKKKGIEVLLLSERIDEWLINH
LHDYKEKALHSVTRGDLDLGALEDEAEKAAQEKLAQESEPLVERFKSALGDKVSDVKITTRLTDTPACVVTGEGEMSSQM
IKLMQAAGQPVPESKPTLELNPTHPLVARLDKEQDETAFAEWAEMLLAQATLSERGSLADPSAFIKLVNQMLLKSVG
>Mature_636_residues
SHQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDSLYEGDGELRVRVSADKDKGTVTIEDN
GIGMTRDGVIEHLGTIAKSGTAEFFKNLSGDSAKDSQLIGQFGVGFYSAFIVAKRVEVFTRAAGHSADEGVKWESEGEGN
FSVETITKAERGTKIVLHLRDEEKEFADDWRLRSIITKYSDHISIPVEMYQEGTPERDGPDGEKIPATEGQWKAMNKATA
LWTRSKSDVSDEEYKEFYKHISHDFADPLDWSHNKVEGNQEYTSLLYIPAKAPWDLWNRDRKHGLKLFVQRVFIMDDAEQ
FMPSYLRFVQGLIDSNDLPLNVSREILQDNKVTRNLRQALTKRVLSMLEKLAKDDADKYQQFWAEFGTVLKEGPAEDFAN
RERIAGLLRFASTHTGDATPSVSLDDYIGRMKEGQEKIYYIVADSHEAAANSPHLELLKKKGIEVLLLSERIDEWLINHL
HDYKEKALHSVTRGDLDLGALEDEAEKAAQEKLAQESEPLVERFKSALGDKVSDVKITTRLTDTPACVVTGEGEMSSQMI
KLMQAAGQPVPESKPTLELNPTHPLVARLDKEQDETAFAEWAEMLLAQATLSERGSLADPSAFIKLVNQMLLKSVG

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=689, Percent_Identity=36.8650217706821, Blast_Score=426, Evalue=1e-119,
Organism=Homo sapiens, GI4507677, Length=686, Percent_Identity=37.3177842565598, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI155722983, Length=645, Percent_Identity=35.0387596899225, Blast_Score=386, Evalue=1e-107,
Organism=Homo sapiens, GI154146191, Length=413, Percent_Identity=36.8038740920097, Blast_Score=273, Evalue=5e-73,
Organism=Homo sapiens, GI153792590, Length=413, Percent_Identity=36.8038740920097, Blast_Score=270, Evalue=3e-72,
Organism=Escherichia coli, GI1786679, Length=633, Percent_Identity=67.7725118483412, Blast_Score=882, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=672, Percent_Identity=37.6488095238095, Blast_Score=440, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17542208, Length=682, Percent_Identity=37.683284457478, Blast_Score=410, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI115535205, Length=659, Percent_Identity=32.9286798179059, Blast_Score=323, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI115535167, Length=439, Percent_Identity=35.7630979498861, Blast_Score=267, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6323840, Length=680, Percent_Identity=37.2058823529412, Blast_Score=447, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6325016, Length=684, Percent_Identity=36.8421052631579, Blast_Score=444, Evalue=1e-125,
Organism=Drosophila melanogaster, GI17647529, Length=687, Percent_Identity=37.7001455604076, Blast_Score=462, Evalue=1e-130,
Organism=Drosophila melanogaster, GI21357739, Length=682, Percent_Identity=38.2697947214076, Blast_Score=424, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24586016, Length=652, Percent_Identity=35.2760736196319, Blast_Score=381, Evalue=1e-105,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_SHEAM (A1S564)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927190.1
- ProteinModelPortal:   A1S564
- SMR:   A1S564
- STRING:   A1S564
- GeneID:   4603565
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1313
- NMPDR:   fig|326297.7.peg.1240
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- PhylomeDB:   A1S564
- ProtClustDB:   PRK05218
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71637; Mature: 71506

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDSLYEGD
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCC
GELRVRVSADKDKGTVTIEDNGIGMTRDGVIEHLGTIAKSGTAEFFKNLSGDSAKDSQLI
CCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHH
GQFGVGFYSAFIVAKRVEVFTRAAGHSADEGVKWESEGEGNFSVETITKAERGTKIVLHL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHCCCCCEEEEEE
RDEEKEFADDWRLRSIITKYSDHISIPVEMYQEGTPERDGPDGEKIPATEGQWKAMNKAT
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
ALWTRSKSDVSDEEYKEFYKHISHDFADPLDWSHNKVEGNQEYTSLLYIPAKAPWDLWNR
HHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHH
DRKHGLKLFVQRVFIMDDAEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNKVTRNLRQA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHH
LTKRVLSMLEKLAKDDADKYQQFWAEFGTVLKEGPAEDFANRERIAGLLRFASTHTGDAT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PSVSLDDYIGRMKEGQEKIYYIVADSHEAAANSPHLELLKKKGIEVLLLSERIDEWLINH
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHH
LHDYKEKALHSVTRGDLDLGALEDEAEKAAQEKLAQESEPLVERFKSALGDKVSDVKITT
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEE
RLTDTPACVVTGEGEMSSQMIKLMQAAGQPVPESKPTLELNPTHPLVARLDKEQDETAFA
EECCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHCCCCHHHHHH
EWAEMLLAQATLSERGSLADPSAFIKLVNQMLLKSVG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SHQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDSLYEGD
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCC
GELRVRVSADKDKGTVTIEDNGIGMTRDGVIEHLGTIAKSGTAEFFKNLSGDSAKDSQLI
CCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHH
GQFGVGFYSAFIVAKRVEVFTRAAGHSADEGVKWESEGEGNFSVETITKAERGTKIVLHL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHCCCCCEEEEEE
RDEEKEFADDWRLRSIITKYSDHISIPVEMYQEGTPERDGPDGEKIPATEGQWKAMNKAT
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
ALWTRSKSDVSDEEYKEFYKHISHDFADPLDWSHNKVEGNQEYTSLLYIPAKAPWDLWNR
HHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHH
DRKHGLKLFVQRVFIMDDAEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNKVTRNLRQA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHH
LTKRVLSMLEKLAKDDADKYQQFWAEFGTVLKEGPAEDFANRERIAGLLRFASTHTGDAT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PSVSLDDYIGRMKEGQEKIYYIVADSHEAAANSPHLELLKKKGIEVLLLSERIDEWLINH
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHH
LHDYKEKALHSVTRGDLDLGALEDEAEKAAQEKLAQESEPLVERFKSALGDKVSDVKITT
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEE
RLTDTPACVVTGEGEMSSQMIKLMQAAGQPVPESKPTLELNPTHPLVARLDKEQDETAFA
EECCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHCCCCHHHHHH
EWAEMLLAQATLSERGSLADPSAFIKLVNQMLLKSVG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA