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The map label for this gene is htrB [H]

Identifier: 119773868

GI number: 119773868

Start: 898426

End: 899373

Strand: Reverse

Name: htrB [H]

Synonym: Sama_0730

Alternate gene names: 119773868

Gene position: 899373-898426 (Counterclockwise)

Preceding gene: 119773872

Following gene: 119773866

Centisome position: 20.89

GC content: 54.75

Gene sequence:

>948_bases
TTGCAACAGAGCGAGCCCCAAGTGGTAGAAAGTGCCCAATTTTCCAATCACCTGTATCACCCCAAGTACTGGCTGTTATG
GCTGGGTGTAGGATTGATGCGCGCCTTGTCGCTGCTGCCCCTGCATTGGCAGATGTCCCTGGGTAAAGGGCTTGGCCAAC
TGGTAAGGATACTGGCAGGCAGTCGCAGCAATACCGCCAGACGTAATCTGGAACTCTGCTTCCCCAACATGAGCGACGCA
GAGCGCGACGCCCTGTTTAAACGTAACTTCGAAGAAACCGGCAAAGCCGTGTTCGATACCATTTGTGCCTGGTGGTGGAG
CGATGAGCGTGTAAAGCAGCATATGCACATCAAGGGAACCGAGCATGTGGAGCAAACCATTGCCGCAGGTCAGGGGGTTA
TCCTGTTTGCGGTACATTGTTTGCCACTGGAAATGGGCGCACGGATTTTTGGCCAGTTTCAACCCGGTGTGGGTGTATAT
CGCCCCCACAACAATGCGGTGATGGAATATCTGCAAGTGAAAGGACGTCTGCGCTCCAATAAGGGGTTGGTGCCCAAGCG
CGATTTGCGTCAGATGGTGCGCTGTTTACGGAATGCCGAGGTGATTTGGTACACGGCCGATCAGGATTTTGGCCGCTCTT
CCGCTGTATTTATTCCCTTCTTTGCCGTGCCGGATGCCGCCACCATTACCGGAGCCACCACCCTGGCCAAGTTGGGCAAA
GCCAGGGTACTGCCGTTTTTTGTGGAGCGGAACGCTGATGATAAGGGCTACAGCATTGAGATTTTGCCGCCGCTGGAAGA
CTTTCCCGGTGAAGACGAAACCGCCGACGCCATCCGTGGTAATCAGGTGGTCGAATCATTGATTTCCCGCAATCTGCCAC
AATACATGTGGCTGCATCGCCGCTTCAAGACGCGCCCGGAGCAGGATGCGCCTTCGCTCTACAAGTAA

Upstream 100 bases:

>100_bases
CTTCATAGTACTCACATTGAATTTGCCGAAACTAAAAGCGGATTGTACCCAATTTTCTCCCGCTGTTGCGCATGTTTTGC
GTTAGAATAAGCACGAATTT

Downstream 100 bases:

>100_bases
CAGCGTCTCGAATTCGCGTTAGGTATCAGCAGCTCAGCCTGCCTTGAGCTTCAAACCAAGGCAGGTTGGACAATCCCCTT
CCATGGTACGCACCACCCAA

Product: lipid A biosynthesis lauroyl acyltransferase

Products: NA

Alternate protein names: Heat shock protein B [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MQQSEPQVVESAQFSNHLYHPKYWLLWLGVGLMRALSLLPLHWQMSLGKGLGQLVRILAGSRSNTARRNLELCFPNMSDA
ERDALFKRNFEETGKAVFDTICAWWWSDERVKQHMHIKGTEHVEQTIAAGQGVILFAVHCLPLEMGARIFGQFQPGVGVY
RPHNNAVMEYLQVKGRLRSNKGLVPKRDLRQMVRCLRNAEVIWYTADQDFGRSSAVFIPFFAVPDAATITGATTLAKLGK
ARVLPFFVERNADDKGYSIEILPPLEDFPGEDETADAIRGNQVVESLISRNLPQYMWLHRRFKTRPEQDAPSLYK

Sequences:

>Translated_315_residues
MQQSEPQVVESAQFSNHLYHPKYWLLWLGVGLMRALSLLPLHWQMSLGKGLGQLVRILAGSRSNTARRNLELCFPNMSDA
ERDALFKRNFEETGKAVFDTICAWWWSDERVKQHMHIKGTEHVEQTIAAGQGVILFAVHCLPLEMGARIFGQFQPGVGVY
RPHNNAVMEYLQVKGRLRSNKGLVPKRDLRQMVRCLRNAEVIWYTADQDFGRSSAVFIPFFAVPDAATITGATTLAKLGK
ARVLPFFVERNADDKGYSIEILPPLEDFPGEDETADAIRGNQVVESLISRNLPQYMWLHRRFKTRPEQDAPSLYK
>Mature_315_residues
MQQSEPQVVESAQFSNHLYHPKYWLLWLGVGLMRALSLLPLHWQMSLGKGLGQLVRILAGSRSNTARRNLELCFPNMSDA
ERDALFKRNFEETGKAVFDTICAWWWSDERVKQHMHIKGTEHVEQTIAAGQGVILFAVHCLPLEMGARIFGQFQPGVGVY
RPHNNAVMEYLQVKGRLRSNKGLVPKRDLRQMVRCLRNAEVIWYTADQDFGRSSAVFIPFFAVPDAATITGATTLAKLGK
ARVLPFFVERNADDKGYSIEILPPLEDFPGEDETADAIRGNQVVESLISRNLPQYMWLHRRFKTRPEQDAPSLYK

Specific function: Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA [H]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI1787292, Length=302, Percent_Identity=45.0331125827815, Blast_Score=280, Evalue=8e-77,
Organism=Escherichia coli, GI87082094, Length=303, Percent_Identity=39.9339933993399, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1788161, Length=295, Percent_Identity=27.7966101694915, Blast_Score=121, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 35898; Mature: 35898

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQSEPQVVESAQFSNHLYHPKYWLLWLGVGLMRALSLLPLHWQMSLGKGLGQLVRILAG
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
SRSNTARRNLELCFPNMSDAERDALFKRNFEETGKAVFDTICAWWWSDERVKQHMHIKGT
CCCCHHHCCCEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCH
EHVEQTIAAGQGVILFAVHCLPLEMGARIFGQFQPGVGVYRPHNNAVMEYLQVKGRLRSN
HHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHCCC
KGLVPKRDLRQMVRCLRNAEVIWYTADQDFGRSSAVFIPFFAVPDAATITGATTLAKLGK
CCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCC
ARVLPFFVERNADDKGYSIEILPPLEDFPGEDETADAIRGNQVVESLISRNLPQYMWLHR
CCEEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
RFKTRPEQDAPSLYK
HHCCCCCCCCCCCCC
>Mature Secondary Structure
MQQSEPQVVESAQFSNHLYHPKYWLLWLGVGLMRALSLLPLHWQMSLGKGLGQLVRILAG
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
SRSNTARRNLELCFPNMSDAERDALFKRNFEETGKAVFDTICAWWWSDERVKQHMHIKGT
CCCCHHHCCCEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCH
EHVEQTIAAGQGVILFAVHCLPLEMGARIFGQFQPGVGVYRPHNNAVMEYLQVKGRLRSN
HHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHCCC
KGLVPKRDLRQMVRCLRNAEVIWYTADQDFGRSSAVFIPFFAVPDAATITGATTLAKLGK
CCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCC
ARVLPFFVERNADDKGYSIEILPPLEDFPGEDETADAIRGNQVVESLISRNLPQYMWLHR
CCEEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
RFKTRPEQDAPSLYK
HHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 7592970 [H]