Click here to switch to the map view.

The map label for this gene is fbp

Identifier: 119773737

GI number: 119773737

Start: 749259

End: 750221

Strand: Reverse

Name: fbp

Synonym: Sama_0599

Alternate gene names: 119773737

Gene position: 750221-749259 (Counterclockwise)

Preceding gene: 119773739

Following gene: 119773736

Centisome position: 17.42

GC content: 58.46

Gene sequence:

>963_bases
ATGCAGACCCTGTCCCAATCCCTTAAACAAAGCGCGATCAGCGAGGAGCTTGCCAGCCTGTTAACCGTGCTGGCCAACAG
CTCCAAAGACATCAGCCAGGCCGTGCGCCGTGGTGCCCTCGCCGGTGTACTCGGCGTTGCAGGCACCGAAAACGTGCAGG
GTGAAGATCAGAAAAAGCTCGACGTTATCACCAACGACATGCTGAAAGACGCATTGGCTGCCCAAGGCTCGGTGAAGGCG
CTGGCCTCGGAAGAAGAAGATGAGATAGTGCCACTGGCTCAGGACGGCCAGTTTCTGGTGTGCTTCGACCCACTTGATGG
CTCTTCCAATATCGACATCAACTCGCTGGTAGGCACCATTTTCTCTGTTCTGCCGGCCCCAAGCGGTGACGTGAGCGAGC
AAAGCTTCCTACAACCTGGCCGCAAGCAGCTGGCGGCAGGTTACGTGCTCTACGGCCCATCCACCATGCTGGCGTTGACC
ACGGGCCAGGGCGTGCAGCTCTTTACCCTCGACCCGGTCAGCGGCGACTACCTGCTGACCGTAGACGGGGTGCAAATAAG
CAAGGACACCGGCGAGTTCGCCATCAATATGTCCAACCAGCGCTTCTGGGAGCCGGGCATGCAGGCCTACATTGCTGACC
TGATTCAGGGCAAAGAAGGCCCGCGCGGCAAGAACTTCAACATGCGCTGGATTGCAGCCATGGTGGGTGATGTGCACCGA
GTGTTGTGCCGCGGCGGACTGTTCACCTACCCCACCGACACTAAGGACCCGAAAAAGCCGTTCAAACTGCGCCTGATGTA
CGAGGCCAACCCAATGGCATTCTTGGTTGAGCAGGCGGGCGGCAAAGCCAGTACCGGCTATGAGACCATTCTCGACATAG
CGCCAAGTGAAATTCACCAGCGCGTGGCGGTAATTTTGGGCTCGGCCAACGAGGTGGATGCCTGTCTGGGTTACCACAAC
TGA

Upstream 100 bases:

>100_bases
AATCGCAAAGGCCACTGAAAATGTCACCAATCTCGGGTATCATTAGCGCCAGAATTATTCCAAAGACCTCCCCAAATTTG
TCTAACCAGAAGGACACAAG

Downstream 100 bases:

>100_bases
GACTGGCGTTAGTCTTTAGTCCGATGGCGGCGGCCTTTGATTGGCAAGCCGCCAAATCGCGCTATAATACGCGCCAACCG
ATTTTCTGAAATCTGATTTC

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MQTLSQSLKQSAISEELASLLTVLANSSKDISQAVRRGALAGVLGVAGTENVQGEDQKKLDVITNDMLKDALAAQGSVKA
LASEEEDEIVPLAQDGQFLVCFDPLDGSSNIDINSLVGTIFSVLPAPSGDVSEQSFLQPGRKQLAAGYVLYGPSTMLALT
TGQGVQLFTLDPVSGDYLLTVDGVQISKDTGEFAINMSNQRFWEPGMQAYIADLIQGKEGPRGKNFNMRWIAAMVGDVHR
VLCRGGLFTYPTDTKDPKKPFKLRLMYEANPMAFLVEQAGGKASTGYETILDIAPSEIHQRVAVILGSANEVDACLGYHN

Sequences:

>Translated_320_residues
MQTLSQSLKQSAISEELASLLTVLANSSKDISQAVRRGALAGVLGVAGTENVQGEDQKKLDVITNDMLKDALAAQGSVKA
LASEEEDEIVPLAQDGQFLVCFDPLDGSSNIDINSLVGTIFSVLPAPSGDVSEQSFLQPGRKQLAAGYVLYGPSTMLALT
TGQGVQLFTLDPVSGDYLLTVDGVQISKDTGEFAINMSNQRFWEPGMQAYIADLIQGKEGPRGKNFNMRWIAAMVGDVHR
VLCRGGLFTYPTDTKDPKKPFKLRLMYEANPMAFLVEQAGGKASTGYETILDIAPSEIHQRVAVILGSANEVDACLGYHN
>Mature_320_residues
MQTLSQSLKQSAISEELASLLTVLANSSKDISQAVRRGALAGVLGVAGTENVQGEDQKKLDVITNDMLKDALAAQGSVKA
LASEEEDEIVPLAQDGQFLVCFDPLDGSSNIDINSLVGTIFSVLPAPSGDVSEQSFLQPGRKQLAAGYVLYGPSTMLALT
TGQGVQLFTLDPVSGDYLLTVDGVQISKDTGEFAINMSNQRFWEPGMQAYIADLIQGKEGPRGKNFNMRWIAAMVGDVHR
VLCRGGLFTYPTDTKDPKKPFKLRLMYEANPMAFLVEQAGGKASTGYETILDIAPSEIHQRVAVILGSANEVDACLGYHN

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI189083692, Length=302, Percent_Identity=45.0331125827815, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI16579888, Length=302, Percent_Identity=45.0331125827815, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI22907028, Length=313, Percent_Identity=42.8115015974441, Blast_Score=244, Evalue=7e-65,
Organism=Escherichia coli, GI1790679, Length=323, Percent_Identity=44.5820433436532, Blast_Score=257, Evalue=8e-70,
Organism=Caenorhabditis elegans, GI17508131, Length=323, Percent_Identity=41.7956656346749, Blast_Score=248, Evalue=4e-66,
Organism=Saccharomyces cerevisiae, GI6323409, Length=304, Percent_Identity=42.7631578947368, Blast_Score=235, Evalue=8e-63,
Organism=Drosophila melanogaster, GI19921562, Length=319, Percent_Identity=39.4984326018809, Blast_Score=219, Evalue=1e-57,
Organism=Drosophila melanogaster, GI45550998, Length=318, Percent_Identity=39.622641509434, Blast_Score=219, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_SHEAM (A1S351)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_926477.1
- ProteinModelPortal:   A1S351
- SMR:   A1S351
- STRING:   A1S351
- GeneID:   4602852
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_0599
- NMPDR:   fig|326297.7.peg.562
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   HWEAPVQ
- PhylomeDB:   A1S351
- ProtClustDB:   PRK09293
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 34306; Mature: 34306

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00124 FBPASE; PS00659 GLYCOSYL_HYDROL_F5

Important sites: BINDING 196-196 BINDING 262-262

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLSQSLKQSAISEELASLLTVLANSSKDISQAVRRGALAGVLGVAGTENVQGEDQKKL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
DVITNDMLKDALAAQGSVKALASEEEDEIVPLAQDGQFLVCFDPLDGSSNIDINSLVGTI
HHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHH
FSVLPAPSGDVSEQSFLQPGRKQLAAGYVLYGPSTMLALTTGQGVQLFTLDPVSGDYLLT
HHHHCCCCCCCCHHHHHCCCHHHHHCCEEEECCCEEEEEECCCCEEEEEECCCCCCEEEE
VDGVQISKDTGEFAINMSNQRFWEPGMQAYIADLIQGKEGPRGKNFNMRWIAAMVGDVHR
ECCEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
VLCRGGLFTYPTDTKDPKKPFKLRLMYEANPMAFLVEQAGGKASTGYETILDIAPSEIHQ
HHHCCCCEECCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHCCHHHHHH
RVAVILGSANEVDACLGYHN
HHHHHCCCCCCHHHHCCCCC
>Mature Secondary Structure
MQTLSQSLKQSAISEELASLLTVLANSSKDISQAVRRGALAGVLGVAGTENVQGEDQKKL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
DVITNDMLKDALAAQGSVKALASEEEDEIVPLAQDGQFLVCFDPLDGSSNIDINSLVGTI
HHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHH
FSVLPAPSGDVSEQSFLQPGRKQLAAGYVLYGPSTMLALTTGQGVQLFTLDPVSGDYLLT
HHHHCCCCCCCCHHHHHCCCHHHHHCCEEEECCCEEEEEECCCCEEEEEECCCCCCEEEE
VDGVQISKDTGEFAINMSNQRFWEPGMQAYIADLIQGKEGPRGKNFNMRWIAAMVGDVHR
ECCEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
VLCRGGLFTYPTDTKDPKKPFKLRLMYEANPMAFLVEQAGGKASTGYETILDIAPSEIHQ
HHHCCCCEECCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHCCHHHHHH
RVAVILGSANEVDACLGYHN
HHHHHCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA