Click here to switch to the map view.

The map label for this gene is ppa [H]

Identifier: 119773736

GI number: 119773736

Start: 748603

End: 749136

Strand: Reverse

Name: ppa [H]

Synonym: Sama_0598

Alternate gene names: 119773736

Gene position: 749136-748603 (Counterclockwise)

Preceding gene: 119773737

Following gene: 119773735

Centisome position: 17.4

GC content: 53.37

Gene sequence:

>534_bases
ATGAGCTTGAATGCAGTGCCAGCGGGCAAATCCCTGCCAGATGATATCTATGTAATCATCGAGATCCCACAGAACCACGA
TCCTATCAAGTACGAAGTGGACAAGGACAGCGGCGCCCTGTTTGTTGACCGCATCATGACTGCTCCTATGTTCTATCCTT
GCAACTACGGTTATGTGAACCAGACTCTGAGCCTGGATGGTGACCCAGTAGACGTACTGGTACCTACCCAGTACCCACTT
CAGCCTGGCAGTGTGATCCGTTGCCGCCCTGTTGGCGTGCTGAAAATGACCGACGAGTCTGGTGAAGACGCCAAAGTGGT
TGCCGTTCCTCACGAGAAAGTGTCCAAAGAATACGGCCACATTCAGGACGTGAACGACCTGCCAGCCCTGCTGAAGGCCC
AGATCAAGCAGTTCTTCGAACATTACAAGGATCTGGAAGTTGGCAAGTGGGTGAAGGTTGAAAGCTGGGAAGACGCCGCT
GCTGCCCGTGCAGAAATCCTCACCAGCGCCGAGCGCTACAACAAGCAAGCCTAA

Upstream 100 bases:

>100_bases
GATGGCGGCGGCCTTTGATTGGCAAGCCGCCAAATCGCGCTATAATACGCGCCAACCGATTTTCTGAAATCTGATTTCAA
TACCGTTAAAGGATATGCAA

Downstream 100 bases:

>100_bases
TCAGGCTGTTTGTGAAAAAGCCGACCTCAAGGTCGGCTTTTTTGTGCACGGAATCAACTATCCAATTGAAACTCAAATAA
ACTGCACAATATCGAATATT

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MSLNAVPAGKSLPDDIYVIIEIPQNHDPIKYEVDKDSGALFVDRIMTAPMFYPCNYGYVNQTLSLDGDPVDVLVPTQYPL
QPGSVIRCRPVGVLKMTDESGEDAKVVAVPHEKVSKEYGHIQDVNDLPALLKAQIKQFFEHYKDLEVGKWVKVESWEDAA
AARAEILTSAERYNKQA

Sequences:

>Translated_177_residues
MSLNAVPAGKSLPDDIYVIIEIPQNHDPIKYEVDKDSGALFVDRIMTAPMFYPCNYGYVNQTLSLDGDPVDVLVPTQYPL
QPGSVIRCRPVGVLKMTDESGEDAKVVAVPHEKVSKEYGHIQDVNDLPALLKAQIKQFFEHYKDLEVGKWVKVESWEDAA
AARAEILTSAERYNKQA
>Mature_176_residues
SLNAVPAGKSLPDDIYVIIEIPQNHDPIKYEVDKDSGALFVDRIMTAPMFYPCNYGYVNQTLSLDGDPVDVLVPTQYPLQ
PGSVIRCRPVGVLKMTDESGEDAKVVAVPHEKVSKEYGHIQDVNDLPALLKAQIKQFFEHYKDLEVGKWVKVESWEDAAA
ARAEILTSAERYNKQA

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=172, Percent_Identity=80.8139534883721, Blast_Score=294, Evalue=2e-81,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19778; Mature: 19646

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNAVPAGKSLPDDIYVIIEIPQNHDPIKYEVDKDSGALFVDRIMTAPMFYPCNYGYVN
CCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEHHHHHCCEECCCCCCCCC
QTLSLDGDPVDVLVPTQYPLQPGSVIRCRPVGVLKMTDESGEDAKVVAVPHEKVSKEYGH
CEEECCCCCEEEEECCCCCCCCCCEEEECCCEEEEEECCCCCCEEEEEECHHHHHHHCCC
IQDVNDLPALLKAQIKQFFEHYKDLEVGKWVKVESWEDAAAARAEILTSAERYNKQA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLNAVPAGKSLPDDIYVIIEIPQNHDPIKYEVDKDSGALFVDRIMTAPMFYPCNYGYVN
CCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEHHHHHCCEECCCCCCCCC
QTLSLDGDPVDVLVPTQYPLQPGSVIRCRPVGVLKMTDESGEDAKVVAVPHEKVSKEYGH
CEEECCCCCEEEEECCCCCCCCCCEEEECCCEEEEEECCCCCCEEEEEECHHHHHHHCCC
IQDVNDLPALLKAQIKQFFEHYKDLEVGKWVKVESWEDAAAARAEILTSAERYNKQA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]