Click here to switch to the map view.

The map label for this gene is hslV

Identifier: 119773581

GI number: 119773581

Start: 544152

End: 544676

Strand: Reverse

Name: hslV

Synonym: Sama_0441

Alternate gene names: 119773581

Gene position: 544676-544152 (Counterclockwise)

Preceding gene: 119773582

Following gene: 119773580

Centisome position: 12.65

GC content: 58.67

Gene sequence:

>525_bases
GTGACTACTATCGTATCCGTCCGCCGTAACAATCAGGTGGTCATCGCAGGTGATGGCCAGGTCTCCCTCGGCAATACCGT
GATGAAGGGCAATGCCCGCAAGGTACGCCGCCTGTACCACGGCAAGGTATTGGCCGGATTTGCCGGTGGCACCGCTGATG
CTTTCACCCTGTTCGAGCGCTTTGAGGCCAAGCTGGAAATGCACCAGGGCCATTTAATGCGCGCAGCGGTGGAGCTCGCC
AAAGACTGGCGCACCGACCGCATGCTGAGAAAACTCGAGGCCCTGCTGGCCGTGGCCGATGCCGAAAGCTCACTCATCAT
TACCGGTAACGGCGACGTAGTGCAGCCCGAAAACGACCTGATTGCCATCGGCTCCGGCGGTAACTTCGCCCAGGCCGCCG
CCACTGCGCTCTTGGAAAACACCGACCTTGGCGCCCTCGAGATTGCCGAAAAGTCACTGACCATCGCCGGCGATATTTGC
GTATTCACCAACCAGTTCAAGACCATCGAAGAACTGAGTTACTGA

Upstream 100 bases:

>100_bases
GGTGGCTTTGTTTTATCCCTTGAAAAGCCCGACCACGACCCCATATAAGCTCTATCCGTCCCCGAAGGCTTATTCTTCGG
ACGCTAAAAGAGGATCCATT

Downstream 100 bases:

>100_bases
GGAATCATCATGTCTGAAATGACTCCCCGCGAGATTGTTCACGAGCTGGACGCCCATATCATTGGTCAGCAAAAAGCCAA
ACGCAGCGTGGCCGTGGCCC

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MTTIVSVRRNNQVVIAGDGQVSLGNTVMKGNARKVRRLYHGKVLAGFAGGTADAFTLFERFEAKLEMHQGHLMRAAVELA
KDWRTDRMLRKLEALLAVADAESSLIITGNGDVVQPENDLIAIGSGGNFAQAAATALLENTDLGALEIAEKSLTIAGDIC
VFTNQFKTIEELSY

Sequences:

>Translated_174_residues
MTTIVSVRRNNQVVIAGDGQVSLGNTVMKGNARKVRRLYHGKVLAGFAGGTADAFTLFERFEAKLEMHQGHLMRAAVELA
KDWRTDRMLRKLEALLAVADAESSLIITGNGDVVQPENDLIAIGSGGNFAQAAATALLENTDLGALEIAEKSLTIAGDIC
VFTNQFKTIEELSY
>Mature_173_residues
TTIVSVRRNNQVVIAGDGQVSLGNTVMKGNARKVRRLYHGKVLAGFAGGTADAFTLFERFEAKLEMHQGHLMRAAVELAK
DWRTDRMLRKLEALLAVADAESSLIITGNGDVVQPENDLIAIGSGGNFAQAAATALLENTDLGALEIAEKSLTIAGDICV
FTNQFKTIEELSY

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=174, Percent_Identity=83.9080459770115, Blast_Score=298, Evalue=1e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_SHEAM (A1S2P5)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_926321.1
- ProteinModelPortal:   A1S2P5
- SMR:   A1S2P5
- STRING:   A1S2P5
- MEROPS:   T01.006
- GeneID:   4602696
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_0441
- NMPDR:   fig|326297.7.peg.415
- eggNOG:   COG5405
- HOGENOM:   HBG288822
- OMA:   AADICVY
- PhylomeDB:   A1S2P5
- ProtClustDB:   PRK05456
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 18738; Mature: 18606

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: ACT_SITE 2-2

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIVSVRRNNQVVIAGDGQVSLGNTVMKGNARKVRRLYHGKVLAGFAGGTADAFTLFER
CCEEEEEECCCEEEEEECCCEEECCEEEECCHHHHHHHHCCCEEEECCCCCHHHHHHHHH
FEAKLEMHQGHLMRAAVELAKDWRTDRMLRKLEALLAVADAESSLIITGNGDVVQPENDL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCEECCCCCE
IAIGSGGNFAQAAATALLENTDLGALEIAEKSLTIAGDICVFTNQFKTIEELSY
EEEECCCCHHHHHHHHHHCCCCCCCEEECCCCEEEECEEEEEECCHHHHHHCCC
>Mature Secondary Structure 
TTIVSVRRNNQVVIAGDGQVSLGNTVMKGNARKVRRLYHGKVLAGFAGGTADAFTLFER
CEEEEEECCCEEEEEECCCEEECCEEEECCHHHHHHHHCCCEEEECCCCCHHHHHHHHH
FEAKLEMHQGHLMRAAVELAKDWRTDRMLRKLEALLAVADAESSLIITGNGDVVQPENDL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCEECCCCCE
IAIGSGGNFAQAAATALLENTDLGALEIAEKSLTIAGDICVFTNQFKTIEELSY
EEEECCCCHHHHHHHHHHCCCCCCCEEECCCCEEEECEEEEEECCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA