| Definition | Shewanella amazonensis SB2B chromosome, complete genome. |
|---|---|
| Accession | NC_008700 |
| Length | 4,306,142 |
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The map label for this gene is ftsI [H]
Identifier: 119773489
GI number: 119773489
Start: 416196
End: 417932
Strand: Direct
Name: ftsI [H]
Synonym: Sama_0348
Alternate gene names: 119773489
Gene position: 416196-417932 (Clockwise)
Preceding gene: 119773488
Following gene: 119773490
Centisome position: 9.67
GC content: 55.67
Gene sequence:
>1737_bases ATGAGTAAGCAGGCAAAACGCAACCAGAAAGCACAACCCATCCCATGGCGTCTTTACGTTGTGGTGGGCTTTGTGTGTCT GCTGTTTACCAGTCTGGTTGGCCGCGCCGCTTATATTCAGTTGATTGAGCCTGACAAACTGCGCCGTGAAAGCGATATGC GCACTCTGCGTACCAGCAGCAGCGACGTGCAGCGGGGGCTTATCACCGACCGCAATGGTGAAATGCTGGCCGTGAGTGTG CCGGTGCAGGCGGTATACGCGGATCCCAAAGAGGTCCACGATAAAAATGGCTTTGCTGATATGCGTCGTTGGCAGGCTCT GGCTGACGTACTCCACGAAAAGCCAGATGCCCTGATTTCCCGGGTTCAAGACAACCCAAGTAAACGCTTTACCTATCTGA AACGGCAAATCACCCCCGCAGTGGCAGAGTATATTCGCCAACTCAAGTTGCCCGGTGTTTACCTTAAACCCGAATCACGC CGCTACTATCCGGCCGGGGAGATCACCGCCCAGCTGATTGGGGTAACCAATATTGATGACGTGGGTATCGAAGGGATTGA AAGTACCTACAATAACTGGCTGACAGGAACCCCTGCCAAGCAGAAAGTCCGCAAATCCCGTGATGGCCATGTGGTTGAGC GTTTGGACATAGTGCAGGAAGGTGAGAGTCCCAACGACCTGGTGCTCAGCATTGATCAGCGCATCCAGCAGCTTGCCTAC CGGGAGCTGAAGCGCGCCACCGAGATGCATCAGGCGACCTCTGGCTCTGTGGTGGTGATCGATGTGCTGACAGGTGAAGT GCTGGCCATGGCCAACACCCCGTCCTACAACCCCAACAGCCGTGATGACTGGCAAAGCTTCAAGATGCGTAACCGTGCGG TGACTGACACCTTCGAGCCCGGCTCAACGGTAAAACCCTTTGTGGTGGCCGCCGCGCTGGAGTCTGGCACTGTCAAAGCA TCTGACATTATCCCCACATCGCCCGGCTGGATGCGTCTGGGCGGACGCCAGGTCCGCGATTCCAACAATTACGGTGACAT GTCGCTGACCAAAATTCTGGTGAAGTCGAGCAACATGGGCGTTGCCAAACTCTCCCTCGGTATGCCGGTAGAGCAGCTGC TTGGTACTTACTACTCCATCGGTTTGGGCAATTATTCGGGTATTGGATTACCGGGCGAAAGTGCCGGCCTCATCCAGGAA AAACATCGCTGGTCTGATTTTGAGCGTGCGACACTGGCCTTTGGTTACGGCCTGACTACCACCACGCTGCAGCTGGCACG CATGTATGCAACCCTGGGTAACGGTGGTGTGCTTTATCCCGCATCCATTCTGAAGTTGAAGCAAAAACCCGAAGGTCAGC AGGTGTTGTCACCTCAGGTGGCCAACAACGTAATGAACATGTTGGTGGGTGTAACTGAGCAGGGTGGTACGGCGCGCAAG GCCCATATCGACGGTTATCCTGTCGCAGGTAAAACAGGTACCAGCCGCAAAGCGGTGGCTGGCGGTTACGGTGACGATTA TCTGGCCACTTTCGCCGGGGTTGCCCCCGTCAATAACCCCCGGCTTGCCATTGCGGTGGTTATCAACGAACCCAAGGGTG ACAGATATTATGGCGGCGATGTGTCGGCGCCTGTGTTTTCAAAGGTGATGGCCGGTGCACTGCAAATGCTGAACGTTGAG CCCATCAGTACCCGCGAGCAAGTGCAGCTGGCGGCGAATTTGCGGGAGGCCGAATGA
Upstream 100 bases:
>100_bases AGCAATCGCTGGCAGAGCACAGCAGGATCACAAGGATAGCGACTAAGGAACTGAATATGGTCAGACCCCTTCCCAATGAA GAAGTGGTAGTGAGAGTGCC
Downstream 100 bases:
>100_bases TGTTGCTGAAAGACTTATTGGCCCCCTGGTTTCATTACGCAGGTACTGAGTCGGTTCACGCCCCTGTGATAGACAGTCGG CAGTTAACCGCTGGCGGCCT
Product: peptidoglycan glycosyltransferase
Products: NA
Alternate protein names: Penicillin-binding protein 3; PBP-3; Peptidoglycan glycosyltransferase 3 [H]
Number of amino acids: Translated: 578; Mature: 577
Protein sequence:
>578_residues MSKQAKRNQKAQPIPWRLYVVVGFVCLLFTSLVGRAAYIQLIEPDKLRRESDMRTLRTSSSDVQRGLITDRNGEMLAVSV PVQAVYADPKEVHDKNGFADMRRWQALADVLHEKPDALISRVQDNPSKRFTYLKRQITPAVAEYIRQLKLPGVYLKPESR RYYPAGEITAQLIGVTNIDDVGIEGIESTYNNWLTGTPAKQKVRKSRDGHVVERLDIVQEGESPNDLVLSIDQRIQQLAY RELKRATEMHQATSGSVVVIDVLTGEVLAMANTPSYNPNSRDDWQSFKMRNRAVTDTFEPGSTVKPFVVAAALESGTVKA SDIIPTSPGWMRLGGRQVRDSNNYGDMSLTKILVKSSNMGVAKLSLGMPVEQLLGTYYSIGLGNYSGIGLPGESAGLIQE KHRWSDFERATLAFGYGLTTTTLQLARMYATLGNGGVLYPASILKLKQKPEGQQVLSPQVANNVMNMLVGVTEQGGTARK AHIDGYPVAGKTGTSRKAVAGGYGDDYLATFAGVAPVNNPRLAIAVVINEPKGDRYYGGDVSAPVFSKVMAGALQMLNVE PISTREQVQLAANLREAE
Sequences:
>Translated_578_residues MSKQAKRNQKAQPIPWRLYVVVGFVCLLFTSLVGRAAYIQLIEPDKLRRESDMRTLRTSSSDVQRGLITDRNGEMLAVSV PVQAVYADPKEVHDKNGFADMRRWQALADVLHEKPDALISRVQDNPSKRFTYLKRQITPAVAEYIRQLKLPGVYLKPESR RYYPAGEITAQLIGVTNIDDVGIEGIESTYNNWLTGTPAKQKVRKSRDGHVVERLDIVQEGESPNDLVLSIDQRIQQLAY RELKRATEMHQATSGSVVVIDVLTGEVLAMANTPSYNPNSRDDWQSFKMRNRAVTDTFEPGSTVKPFVVAAALESGTVKA SDIIPTSPGWMRLGGRQVRDSNNYGDMSLTKILVKSSNMGVAKLSLGMPVEQLLGTYYSIGLGNYSGIGLPGESAGLIQE KHRWSDFERATLAFGYGLTTTTLQLARMYATLGNGGVLYPASILKLKQKPEGQQVLSPQVANNVMNMLVGVTEQGGTARK AHIDGYPVAGKTGTSRKAVAGGYGDDYLATFAGVAPVNNPRLAIAVVINEPKGDRYYGGDVSAPVFSKVMAGALQMLNVE PISTREQVQLAANLREAE >Mature_577_residues SKQAKRNQKAQPIPWRLYVVVGFVCLLFTSLVGRAAYIQLIEPDKLRRESDMRTLRTSSSDVQRGLITDRNGEMLAVSVP VQAVYADPKEVHDKNGFADMRRWQALADVLHEKPDALISRVQDNPSKRFTYLKRQITPAVAEYIRQLKLPGVYLKPESRR YYPAGEITAQLIGVTNIDDVGIEGIESTYNNWLTGTPAKQKVRKSRDGHVVERLDIVQEGESPNDLVLSIDQRIQQLAYR ELKRATEMHQATSGSVVVIDVLTGEVLAMANTPSYNPNSRDDWQSFKMRNRAVTDTFEPGSTVKPFVVAAALESGTVKAS DIIPTSPGWMRLGGRQVRDSNNYGDMSLTKILVKSSNMGVAKLSLGMPVEQLLGTYYSIGLGNYSGIGLPGESAGLIQEK HRWSDFERATLAFGYGLTTTTLQLARMYATLGNGGVLYPASILKLKQKPEGQQVLSPQVANNVMNMLVGVTEQGGTARKA HIDGYPVAGKTGTSRKAVAGGYGDDYLATFAGVAPVNNPRLAIAVVINEPKGDRYYGGDVSAPVFSKVMAGALQMLNVEP ISTREQVQLAANLREAE
Specific function: Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]
COG id: COG0768
COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2
Gene ontology:
Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side. Note=The bulk of the molecule, except for the N-terminal membrane anchor region, protrudes into the periplasmic space, where it acts on murein (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786272, Length=560, Percent_Identity=49.1071428571429, Blast_Score=555, Evalue=1e-159, Organism=Escherichia coli, GI1786854, Length=586, Percent_Identity=26.4505119453925, Blast_Score=140, Evalue=2e-34,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR005311 - InterPro: IPR001460 [H]
Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]
EC number: =2.4.1.129 [H]
Molecular weight: Translated: 63352; Mature: 63221
Theoretical pI: Translated: 9.66; Mature: 9.66
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSKQAKRNQKAQPIPWRLYVVVGFVCLLFTSLVGRAAYIQLIEPDKLRRESDMRTLRTSS CCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHCCC SDVQRGLITDRNGEMLAVSVPVQAVYADPKEVHDKNGFADMRRWQALADVLHEKPDALIS HHHHHCCEECCCCCEEEEECCEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHH RVQDNPSKRFTYLKRQITPAVAEYIRQLKLPGVYLKPESRRYYPAGEITAQLIGVTNIDD HHHCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHEEEEECCCCCC VGIEGIESTYNNWLTGTPAKQKVRKSRDGHVVERLDIVQEGESPNDLVLSIDQRIQQLAY CCCCHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHH RELKRATEMHQATSGSVVVIDVLTGEVLAMANTPSYNPNSRDDWQSFKMRNRAVTDTFEP HHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCC GSTVKPFVVAAALESGTVKASDIIPTSPGWMRLGGRQVRDSNNYGDMSLTKILVKSSNMG CCCCCHHHEEEECCCCCEEECCCCCCCCCCEECCCEEECCCCCCCCHHHHHHHHCCCCCC VAKLSLGMPVEQLLGTYYSIGLGNYSGIGLPGESAGLIQEKHRWSDFERATLAFGYGLTT EEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHEEECCCHHH TTLQLARMYATLGNGGVLYPASILKLKQKPEGQQVLSPQVANNVMNMLVGVTEQGGTARK HHHHHHHHHHHHCCCCEECCHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCEEE AHIDGYPVAGKTGTSRKAVAGGYGDDYLATFAGVAPVNNPRLAIAVVINEPKGDRYYGGD EECCCCCCCCCCCCCCCEEECCCCCHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCC VSAPVFSKVMAGALQMLNVEPISTREQVQLAANLREAE CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC >Mature Secondary Structure SKQAKRNQKAQPIPWRLYVVVGFVCLLFTSLVGRAAYIQLIEPDKLRRESDMRTLRTSS CCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHCCC SDVQRGLITDRNGEMLAVSVPVQAVYADPKEVHDKNGFADMRRWQALADVLHEKPDALIS HHHHHCCEECCCCCEEEEECCEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHH RVQDNPSKRFTYLKRQITPAVAEYIRQLKLPGVYLKPESRRYYPAGEITAQLIGVTNIDD HHHCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHEEEEECCCCCC VGIEGIESTYNNWLTGTPAKQKVRKSRDGHVVERLDIVQEGESPNDLVLSIDQRIQQLAY CCCCHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHH RELKRATEMHQATSGSVVVIDVLTGEVLAMANTPSYNPNSRDDWQSFKMRNRAVTDTFEP HHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCC GSTVKPFVVAAALESGTVKASDIIPTSPGWMRLGGRQVRDSNNYGDMSLTKILVKSSNMG CCCCCHHHEEEECCCCCEEECCCCCCCCCCEECCCEEECCCCCCCCHHHHHHHHCCCCCC VAKLSLGMPVEQLLGTYYSIGLGNYSGIGLPGESAGLIQEKHRWSDFERATLAFGYGLTT EEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHEEECCCHHH TTLQLARMYATLGNGGVLYPASILKLKQKPEGQQVLSPQVANNVMNMLVGVTEQGGTARK HHHHHHHHHHHHCCCCEECCHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCEEE AHIDGYPVAGKTGTSRKAVAGGYGDDYLATFAGVAPVNNPRLAIAVVINEPKGDRYYGGD EECCCCCCCCCCCCCCCEEECCCCCHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCC VSAPVFSKVMAGALQMLNVEPISTREQVQLAANLREAE CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]