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The map label for this gene is trpB [H]

Identifier: 119717250

GI number: 119717250

Start: 3226677

End: 3227957

Strand: Reverse

Name: trpB [H]

Synonym: Noca_3026

Alternate gene names: 119717250

Gene position: 3227957-3226677 (Counterclockwise)

Preceding gene: 119717251

Following gene: 119717249

Centisome position: 64.74

GC content: 73.77

Gene sequence:

>1281_bases
ATGACGACCAGGCCCGAGCGGACGACGACGTACGACGCGGACGCGCTCGGCTGGTTCGGCGGCCCCGCGGAGGGCTTCGG
CGGGCGGTTCATGCCCGAGGCCCTGGTGGCGGCCCTCGACGAGCTCACCGTCGCCTGGCAGGACGCGATGGCCGATCCGG
AGTTCGTCGCGGAGTTCGACACGATCCTGCGCGAGTACGCCGGCCTCCCGAGCCCGCTCTACGTCGCCGAGCGGCTCAGC
GCCCAGGTCGGTGCCCGGATCCTGCTCAAGCGCGAGGACCTCGCCCACACCGGCGCGCACAAGATCCGCAACGTGCTGGG
CCAGGCGCTGCTGACCCGGCGGATGGGCAAGACCCGGGTGATCGCGGAGACCGGCGCCGGGCAGCACGGCGTGGCCAGCG
CGACGGCCGCGGCCTACTTCGGTCTCGACTGCACGGTCTACATGGGCTCGGTCGACACCCGGCGGCAGGCGCTCAACGTC
GCCCGGATGAACCTGCTCGGCGCCACCGTCGTCCCCGTCGACTCCGGCAGCGCCACGCTCAAGGACGCGATCAACGAGGC
GCTGCGCGACTGGGTCGCCACCGTCGACCACACGGCATACCTCTTCGGCACCGCGGCCGGGCCGCACCCGTTCCCCAGCA
TGGTCCGCGACTTCACCCGCGGCATCGGCGACGAGGCCCGGGCGCAGTGCCTCGAGCGCTTCGGCCGGCTCCCGGACGCG
ATCGCGGCCTGCGTCGGCGGGGGCTCCAACGCGATCGGCCTGTTCTCGGCCTTCCTCGACGACGCGGACGTCGCGATCTA
CGGGTTCGAGGCCGGTGGCGAGGGCTTCGAGACCGGCCGGCACGCCGCCACGATCCACGCGGGGGACCGCGGCGTCCTGC
ACGGGGCGCGCACCTACGTCCTCCAGGACGAGGACGGCCAGACCCTCGAGTCGCACTCGATCTCGGCCGGGCTGGACTAC
CCCGGCGTCGGCCCGCAGCACGCGCACCTGGCCGCGACCGGGCGCGCGACGTACCTCCCGGTGACCGACGACGAGGCCAT
GGCGGCACTCGCCCTCCTCAGCCGCACCGAGGGCATCATCCCGGCGATCGAGTCCGCTCACGCTGTCGCCGGCGGGCTCC
GGGTCGCCGAGCGGCTGGCCGCGGAGCAGGGGCCGGACGCGACGGTGCTGATCAACCTGAGCGGGCGCGGCGACAAGGAC
ATGGGCACCGCGATCGAGTACTTCGGCCTGGTCGACGGCCAGCACGCCGGAGGCCACGGAGCCGGGGAGCCGATCGGATG
A

Upstream 100 bases:

>100_bases
GGTTCGTGCGCGAGGGGGCCCGGGCCGTGCTCGTGGGCGAGGCACTGGTGAAGGACGGCGACCCCGAGGGCGCAGTGCGC
AGGATGACAGGAGTCGAGTC

Downstream 100 bases:

>100_bases
GCACGCGGACCGCGTTCGACACGGCGAGGGCCGAGGGCCGGGCGGCGCTCGTGGGCTACCTGCCGGCGGGCTTCCCGGAC
GTCGCCGGGGGCATCGACGC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MTTRPERTTTYDADALGWFGGPAEGFGGRFMPEALVAALDELTVAWQDAMADPEFVAEFDTILREYAGLPSPLYVAERLS
AQVGARILLKREDLAHTGAHKIRNVLGQALLTRRMGKTRVIAETGAGQHGVASATAAAYFGLDCTVYMGSVDTRRQALNV
ARMNLLGATVVPVDSGSATLKDAINEALRDWVATVDHTAYLFGTAAGPHPFPSMVRDFTRGIGDEARAQCLERFGRLPDA
IAACVGGGSNAIGLFSAFLDDADVAIYGFEAGGEGFETGRHAATIHAGDRGVLHGARTYVLQDEDGQTLESHSISAGLDY
PGVGPQHAHLAATGRATYLPVTDDEAMAALALLSRTEGIIPAIESAHAVAGGLRVAERLAAEQGPDATVLINLSGRGDKD
MGTAIEYFGLVDGQHAGGHGAGEPIG

Sequences:

>Translated_426_residues
MTTRPERTTTYDADALGWFGGPAEGFGGRFMPEALVAALDELTVAWQDAMADPEFVAEFDTILREYAGLPSPLYVAERLS
AQVGARILLKREDLAHTGAHKIRNVLGQALLTRRMGKTRVIAETGAGQHGVASATAAAYFGLDCTVYMGSVDTRRQALNV
ARMNLLGATVVPVDSGSATLKDAINEALRDWVATVDHTAYLFGTAAGPHPFPSMVRDFTRGIGDEARAQCLERFGRLPDA
IAACVGGGSNAIGLFSAFLDDADVAIYGFEAGGEGFETGRHAATIHAGDRGVLHGARTYVLQDEDGQTLESHSISAGLDY
PGVGPQHAHLAATGRATYLPVTDDEAMAALALLSRTEGIIPAIESAHAVAGGLRVAERLAAEQGPDATVLINLSGRGDKD
MGTAIEYFGLVDGQHAGGHGAGEPIG
>Mature_425_residues
TTRPERTTTYDADALGWFGGPAEGFGGRFMPEALVAALDELTVAWQDAMADPEFVAEFDTILREYAGLPSPLYVAERLSA
QVGARILLKREDLAHTGAHKIRNVLGQALLTRRMGKTRVIAETGAGQHGVASATAAAYFGLDCTVYMGSVDTRRQALNVA
RMNLLGATVVPVDSGSATLKDAINEALRDWVATVDHTAYLFGTAAGPHPFPSMVRDFTRGIGDEARAQCLERFGRLPDAI
AACVGGGSNAIGLFSAFLDDADVAIYGFEAGGEGFETGRHAATIHAGDRGVLHGARTYVLQDEDGQTLESHSISAGLDYP
GVGPQHAHLAATGRATYLPVTDDEAMAALALLSRTEGIIPAIESAHAVAGGLRVAERLAAEQGPDATVLINLSGRGDKDM
GTAIEYFGLVDGQHAGGHGAGEPIG

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=380, Percent_Identity=55.5263157894737, Blast_Score=429, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6321412, Length=383, Percent_Identity=54.5691906005222, Blast_Score=413, Evalue=1e-116,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 44581; Mature: 44450

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRPERTTTYDADALGWFGGPAEGFGGRFMPEALVAALDELTVAWQDAMADPEFVAEFD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TILREYAGLPSPLYVAERLSAQVGARILLKREDLAHTGAHKIRNVLGQALLTRRMGKTRV
HHHHHHCCCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IAETGAGQHGVASATAAAYFGLDCTVYMGSVDTRRQALNVARMNLLGATVVPVDSGSATL
EEECCCCCCCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCEEEEECCCCHHH
KDAINEALRDWVATVDHTAYLFGTAAGPHPFPSMVRDFTRGIGDEARAQCLERFGRLPDA
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHH
IAACVGGGSNAIGLFSAFLDDADVAIYGFEAGGEGFETGRHAATIHAGDRGVLHGARTYV
HHHHHCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCEECCCEEEE
LQDEDGQTLESHSISAGLDYPGVGPQHAHLAATGRATYLPVTDDEAMAALALLSRTEGII
EECCCCCCHHHCCCCCCCCCCCCCCCCCEEEECCCEEEEECCCHHHHHHHHHHHHCCCCC
PAIESAHAVAGGLRVAERLAAEQGPDATVLINLSGRGDKDMGTAIEYFGLVDGQHAGGHG
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCC
AGEPIG
CCCCCC
>Mature Secondary Structure 
TTRPERTTTYDADALGWFGGPAEGFGGRFMPEALVAALDELTVAWQDAMADPEFVAEFD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TILREYAGLPSPLYVAERLSAQVGARILLKREDLAHTGAHKIRNVLGQALLTRRMGKTRV
HHHHHHCCCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IAETGAGQHGVASATAAAYFGLDCTVYMGSVDTRRQALNVARMNLLGATVVPVDSGSATL
EEECCCCCCCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCEEEEECCCCHHH
KDAINEALRDWVATVDHTAYLFGTAAGPHPFPSMVRDFTRGIGDEARAQCLERFGRLPDA
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHH
IAACVGGGSNAIGLFSAFLDDADVAIYGFEAGGEGFETGRHAATIHAGDRGVLHGARTYV
HHHHHCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCEECCCEEEE
LQDEDGQTLESHSISAGLDYPGVGPQHAHLAATGRATYLPVTDDEAMAALALLSRTEGII
EECCCCCCHHHCCCCCCCCCCCCCCCCCEEEECCCEEEEECCCHHHHHHHHHHHHCCCCC
PAIESAHAVAGGLRVAERLAAEQGPDATVLINLSGRGDKDMGTAIEYFGLVDGQHAGGHG
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCC
AGEPIG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA