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The map label for this gene is ackA [H]

Identifier: 119717177

GI number: 119717177

Start: 3138749

End: 3139957

Strand: Reverse

Name: ackA [H]

Synonym: Noca_2953

Alternate gene names: 119717177

Gene position: 3139957-3138749 (Counterclockwise)

Preceding gene: 119717178

Following gene: 119717172

Centisome position: 62.98

GC content: 73.2

Gene sequence:

>1209_bases
ATGAGTGCGCTGGTCCTGGTCATCAACGCCGGCTCGTCCTCGCTGAAGTACAGCCTGATCGACGCCGAGAGCGGTGCCAG
CCACGCCGTCGGGCTGGCCGAGCGGATCGCGGACTCCTCGGGTGCCGGCGGCAGCCTCAGCCACACCGGCCCGGACGGGG
TGAAGCACCGCAGTGAGCTGCCGCTGCCCTCCCACGAGGCCGCGCTCCGGGCGGCGCTGGACGCGTTCGCCGCGCACGGC
CCGTCGCTGGAGGACGCGACGATCACCGCGGTGGGCCACCGGATGGTGCACGGCGGTGAGCGGTTCTCCGAGCCCGCGCT
GGTCGACGACGCGCTGGTCGACGCCGTACGCGAGCTGGTGCCGCTCGCGCCGCTGCACAACCCCGCCAACCTGGAGGCGC
TCGGGGTGGCGCGCCGGCTCTTCGACACCCTCCCGCACGTCGCGGTGTTCGACACCGCCTTCCACCAGACGCTACCCGAG
CAGGCCTACACCTACGCGGTGCCGCACGAGTGGCGCGAGGAGCACGGGATCCGCCGCTACGGCTTCCACGGCACCTCGCA
CAAGTTCGTCTCCGGCGAGACCGCCCGGCTGCTCGGCCGCCCGGTCGAGGACACGAACACGATCGTCCTGCACCTCGGCA
ACGGCGCCTCGGCGACAGCGGTCGCGGGCGGCCGGTCCGTGGACACGTCGATGGGTCTCACCCCGCTCGAGGGCCTGGTG
ATGGGCACCCGCTCCGGCGACGTCGACCCGGCGCTGCACGCCCACCTGCACCGGCAGCTCGGCTGGTCGCTGGAGGAGAT
CGACCAGCGGCTCAACCGCAACTCCGGCATCAAGGGCCTGCTCGGCTTCAGCGACTTCCGCGAGCTGGGGCGGCTGCTCG
AGGAGGGGGAGCCGCGCGCCCGGCTCGCCATGGACGTCTACTGCTACCGGCTGCGCAAGTACGTCGGCGCGTACTACGCC
GTGCTCGGCCGGGTCGACGCGATCGCGTTCACCGGCGGGGTGGGGGAGCACGTGCCGGACGTGCGCGCCCAGGCGCTCGC
CGGCCTGGAGCGGCTCGGCATCCGGATCGACGCCGAGGCCAACCGGGGCGGGCACTCGGGCGCGTTCACGGTGTCGGCCG
AGGACAGCGAGGTCGCCGTGCTGGTCGTGCCGACCAACGAGGAGTGGCAGATTGCCCGGGAGTCCCTCGACGTCGTCCGA
GGCGGCTGA

Upstream 100 bases:

>100_bases
AGCCGGTCAACGACCTGTCCCGCGGCGCGACGGTTCGCGACATCGTCAACACCGTCGCGATCACCGCTGTCCAGGCCCAG
CAGCTCGCCGAGGTCGCCCG

Downstream 100 bases:

>100_bases
GCCCGCGGCTCAGACCAGCTGCTCCAGCAGCCCGGTGTCGACGTCGTAGATGAACCCGCCGACCTTGACCGCGTCGGGGA
CCAGCGGGTGGGACACCACC

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MSALVLVINAGSSSLKYSLIDAESGASHAVGLAERIADSSGAGGSLSHTGPDGVKHRSELPLPSHEAALRAALDAFAAHG
PSLEDATITAVGHRMVHGGERFSEPALVDDALVDAVRELVPLAPLHNPANLEALGVARRLFDTLPHVAVFDTAFHQTLPE
QAYTYAVPHEWREEHGIRRYGFHGTSHKFVSGETARLLGRPVEDTNTIVLHLGNGASATAVAGGRSVDTSMGLTPLEGLV
MGTRSGDVDPALHAHLHRQLGWSLEEIDQRLNRNSGIKGLLGFSDFRELGRLLEEGEPRARLAMDVYCYRLRKYVGAYYA
VLGRVDAIAFTGGVGEHVPDVRAQALAGLERLGIRIDAEANRGGHSGAFTVSAEDSEVAVLVVPTNEEWQIARESLDVVR
GG

Sequences:

>Translated_402_residues
MSALVLVINAGSSSLKYSLIDAESGASHAVGLAERIADSSGAGGSLSHTGPDGVKHRSELPLPSHEAALRAALDAFAAHG
PSLEDATITAVGHRMVHGGERFSEPALVDDALVDAVRELVPLAPLHNPANLEALGVARRLFDTLPHVAVFDTAFHQTLPE
QAYTYAVPHEWREEHGIRRYGFHGTSHKFVSGETARLLGRPVEDTNTIVLHLGNGASATAVAGGRSVDTSMGLTPLEGLV
MGTRSGDVDPALHAHLHRQLGWSLEEIDQRLNRNSGIKGLLGFSDFRELGRLLEEGEPRARLAMDVYCYRLRKYVGAYYA
VLGRVDAIAFTGGVGEHVPDVRAQALAGLERLGIRIDAEANRGGHSGAFTVSAEDSEVAVLVVPTNEEWQIARESLDVVR
GG
>Mature_401_residues
SALVLVINAGSSSLKYSLIDAESGASHAVGLAERIADSSGAGGSLSHTGPDGVKHRSELPLPSHEAALRAALDAFAAHGP
SLEDATITAVGHRMVHGGERFSEPALVDDALVDAVRELVPLAPLHNPANLEALGVARRLFDTLPHVAVFDTAFHQTLPEQ
AYTYAVPHEWREEHGIRRYGFHGTSHKFVSGETARLLGRPVEDTNTIVLHLGNGASATAVAGGRSVDTSMGLTPLEGLVM
GTRSGDVDPALHAHLHRQLGWSLEEIDQRLNRNSGIKGLLGFSDFRELGRLLEEGEPRARLAMDVYCYRLRKYVGAYYAV
LGRVDAIAFTGGVGEHVPDVRAQALAGLERLGIRIDAEANRGGHSGAFTVSAEDSEVAVLVVPTNEEWQIARESLDVVRG
G

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=404, Percent_Identity=46.5346534653465, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI145693184, Length=395, Percent_Identity=43.5443037974684, Blast_Score=305, Evalue=4e-84,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 42857; Mature: 42725

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALVLVINAGSSSLKYSLIDAESGASHAVGLAERIADSSGAGGSLSHTGPDGVKHRSEL
CCEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PLPSHEAALRAALDAFAAHGPSLEDATITAVGHRMVHGGERFSEPALVDDALVDAVRELV
CCCCHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
PLAPLHNPANLEALGVARRLFDTLPHVAVFDTAFHQTLPEQAYTYAVPHEWREEHGIRRY
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHEEEECCHHHHHHCCCEEE
GFHGTSHKFVSGETARLLGRPVEDTNTIVLHLGNGASATAVAGGRSVDTSMGLTPLEGLV
CCCCCCCCEECCCHHHHHCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCHHHEE
MGTRSGDVDPALHAHLHRQLGWSLEEIDQRLNRNSGIKGLLGFSDFRELGRLLEEGEPRA
EECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHCCCCHH
RLAMDVYCYRLRKYVGAYYAVLGRVDAIAFTGGVGEHVPDVRAQALAGLERLGIRIDAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHCEEEECCC
NRGGHSGAFTVSAEDSEVAVLVVPTNEEWQIARESLDVVRGG
CCCCCCCEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SALVLVINAGSSSLKYSLIDAESGASHAVGLAERIADSSGAGGSLSHTGPDGVKHRSEL
CEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PLPSHEAALRAALDAFAAHGPSLEDATITAVGHRMVHGGERFSEPALVDDALVDAVRELV
CCCCHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
PLAPLHNPANLEALGVARRLFDTLPHVAVFDTAFHQTLPEQAYTYAVPHEWREEHGIRRY
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHEEEECCHHHHHHCCCEEE
GFHGTSHKFVSGETARLLGRPVEDTNTIVLHLGNGASATAVAGGRSVDTSMGLTPLEGLV
CCCCCCCCEECCCHHHHHCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCHHHEE
MGTRSGDVDPALHAHLHRQLGWSLEEIDQRLNRNSGIKGLLGFSDFRELGRLLEEGEPRA
EECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHCCCCHH
RLAMDVYCYRLRKYVGAYYAVLGRVDAIAFTGGVGEHVPDVRAQALAGLERLGIRIDAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHCEEEECCC
NRGGHSGAFTVSAEDSEVAVLVVPTNEEWQIARESLDVVRGG
CCCCCCCEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA