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The map label for this gene is hlyU [H]

Identifier: 119717151

GI number: 119717151

Start: 3108483

End: 3108818

Strand: Reverse

Name: hlyU [H]

Synonym: Noca_2927

Alternate gene names: 119717151

Gene position: 3108818-3108483 (Counterclockwise)

Preceding gene: 119717152

Following gene: 119717150

Centisome position: 62.35

GC content: 69.05

Gene sequence:

>336_bases
GTGGACCGAGACGTCGCAGCCGAGCTGCACGAGCTGCACGCCCGCGTGTGCAAGGCCATCGCGGACCCCAAGCGGCTGCT
GATCATCAACGAGCTGCGTGACGGCGAGCTGTCGGTCGGTGACCTGTCCGAGGCGCTCGCGATCAGCCACTCCAACGCCA
GCCAGCACCTGGCCGTCCTGCGCGATCGCGGCATGGTGACGACCCGACGGGTCGGCACGACCGTTTACTACAGCCTGCGC
AGCACCAAGATCGTCCAGGCGGTCGACCTGCTGCGCGAGTTCCTCGCCGACGACCTGGCCGAGCGCGGACGGCTCGGTGA
CGTGATCGCCGGCTGA

Upstream 100 bases:

>100_bases
GGCCGCCACCGGCGTCGTCGTGGGCACCGCGGCCTGGCACGGCTAGCTCACACTAGACTCCTGTCTCGACGGTGCACGAG
CTGCGGAGGAGGGAGTGCCG

Downstream 100 bases:

>100_bases
CGGGGCTGGGCGGGAGCAGACACTGACGGTGCCGGCCGTCAGCCGTGGACTTGTCGCCTGGGGGCTTGCTGCGTCTCGAG
GACCAGTTTCAGTGAACCTT

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 111; Mature: 111

Protein sequence:

>111_residues
MDRDVAAELHELHARVCKAIADPKRLLIINELRDGELSVGDLSEALAISHSNASQHLAVLRDRGMVTTRRVGTTVYYSLR
STKIVQAVDLLREFLADDLAERGRLGDVIAG

Sequences:

>Translated_111_residues
MDRDVAAELHELHARVCKAIADPKRLLIINELRDGELSVGDLSEALAISHSNASQHLAVLRDRGMVTTRRVGTTVYYSLR
STKIVQAVDLLREFLADDLAERGRLGDVIAG
>Mature_111_residues
MDRDVAAELHELHARVCKAIADPKRLLIINELRDGELSVGDLSEALAISHSNASQHLAVLRDRGMVTTRRVGTTVYYSLR
STKIVQAVDLLREFLADDLAERGRLGDVIAG

Specific function: Up-regulates the expression of the hemolysin gene, hlyA, and may promote expression of other virulence determinants in vivo. It may have both positive and negative regulator activities [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12220; Mature: 12220

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRDVAAELHELHARVCKAIADPKRLLIINELRDGELSVGDLSEALAISHSNASQHLAVL
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHH
RDRGMVTTRRVGTTVYYSLRSTKIVQAVDLLREFLADDLAERGRLGDVIAG
HHCCCEEEHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDRDVAAELHELHARVCKAIADPKRLLIINELRDGELSVGDLSEALAISHSNASQHLAVL
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHH
RDRGMVTTRRVGTTVYYSLRSTKIVQAVDLLREFLADDLAERGRLGDVIAG
HHCCCEEEHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]