| Definition | Nocardioides sp. JS614 chromosome, complete genome. |
|---|---|
| Accession | NC_008699 |
| Length | 4,985,871 |
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The map label for this gene is cobB [H]
Identifier: 119717111
GI number: 119717111
Start: 3068607
End: 3071018
Strand: Reverse
Name: cobB [H]
Synonym: Noca_2887
Alternate gene names: 119717111
Gene position: 3071018-3068607 (Counterclockwise)
Preceding gene: 119717112
Following gene: 119717110
Centisome position: 61.59
GC content: 72.14
Gene sequence:
>2412_bases GTGGCGGCGCCATCGACCGGTCAAGGCAAGACGACCGTCGCGACGGGGCTGATGGCGGCCCTGCGCATCTCCGGCCACGA GGTCAGCGGCCACAAGGTCGGGCCGGACTACATCGACCCCGGCTACCACGCCCTCGCCACCGGAAGACCCGGCCGCAACC TCGACCCCCACCTGGTGGGGGAGGAGCGGATCGTCCCGTTGCTGCTCCACGGCGCGTGCGGCGCCGACATCGCGGTCATC GAAGGCGTCATGGGCCTCTACGACGGCCGCCTCGGCACCGACGGCTTCGCCTCGACCGCTCACGTCGCGACGCTCACCCG CTCACCCGTCGTGCTCGTCGTCGACGTGGCCCGGCTGTCTCGCACCGCGGCGGCGATCGCCGCAGGCATGGCGGCGTTCG ACGACGGCCTCGAGATCGCCGGTGTCGTCCTCAACCGCACCGGCTCGGCAGCGAACGACGCCGAGATCGTGCGCGCCATG GAGCGCACCGGGCTGCCCGTCCTCGGCCGCCTCCCTCGCAACGAGGATCTCGCCACACCGTCGCGCCACCTCGGCCTGGT GCCCGCCGCCGAACGCGACGAGTCCGCCGCCATGCTGCACCGCCTCGGTGAGCAGGTCGCCGAGCACCTCGACCTCGACG CAGTGCTGACGATCGCACGCGCCGCGCCAGAGCTTGACGCGGAACCGTGGGAACCGCACGCCGAGATCACGGCGGGTGGT GACGGGCGACCGGTCATCGCGGTGGCCGGAGGCCGCGCCTTCACGTTCCGCTACGCCGAGACAGAGGAGCTGCTGCGGGC CGCGGGCTGCGAGGTCGTCACCTTCGATCCGATCAGCGACCCGGCCCTTCCGCCGCGCACGCAGGGGATCTACCTCGGCG GCGGGTTCCCCGAGGTCTACGCCGCAGAGCTCGCCGCCAACCGCCGCCTACTCGACGACCTGCGCGCCGCCGTCGACACG GGTGTGCCGACGGTCGCCGAGTGCGCCGGCCTGCTCTACCTCGCCGAGACCCTCGATGGTGCACCGATGGCCGCCGCCCT TCCGTTCACGGCTGCCATGAACGAGCGACTGACGCTGCGCTATCCCACGGCCACCGCAGCAACGGACTCGCTGCTCACCC GGGTCGGTGAGAGGGTCACCGGTCACGAGTTCCACCGCACCCAGATCTCGCCCGCGAGCAGCATCCGGCCAGCGTGGACC ATCGACGGCCTGCCGACCGGACACGCGACCGATATCGTGCACGCGTCGTACCTCCACGTCCATTGGGCCGGCCACCCGCG ACTCGCCCAGCGCTTCGCTGACGCCGCACACCGCGCGGTGCCGCACGCCACCGAGCCGCGCGAGGCCGTTGCCGCCCGTG ACCAACCGGCGACCGCGACGCCACGCCCGACCGAGCCCCTGCGCCACCACGGCGACGCCGAGACCGGGCCCGACCTGCTC GACTTCGCCGTGAACGTGTACGACGCCCGACGGCCGCCGTGGCTCGACCACGCTCTCGCCATGTCGGTCGCAGAGGTCCA GGCCTATCCCGACGCGACCCCGGCCGCTGCCGCGATCGCTCAACGGCACGGCCGCAAGCTCGACGAGATCCTCCCGACAG CAGGGGCGGCTGAAGCCTTCAGCCTCATCGCACGACTCCGATCCTGGCAGAAGCCGGTCGTCATCCATCCGCAGTTCACC GAGCCGCACGCCGCGCTCGAGCAGGCCGGCCACGAGGTCACCTCCGTGCTGTGCCGACCGGAGGACGGCTATTCACTCGA CCCGGCAGCGGTTCCCGAGGATGCCGACCTCGTCATCGTCGGCAATCCCACGAACCCGACCGGCGTCCTGCACCAGGCGA GCACGATCAGCCGACTGCGCCGCAAGGGCCGACTGGTCGTGGTCGACGAGGCGTTCATGGACGCCGTGCCCGGCGAGGCC GAGTCCCTGATCCGCGAGCGGCTCCGCGACCTCGTCGTCATCCGAAGCCTCACCAAGCACTGGTCGATCCCAGGCATCCG CGCCGGCTACGTGGTGGGTCACCGCCTCGTCATCAAGCACCTCGCCCGACGCCAGACCCCATGGTCGGTCTCGACCCCGG CGATCGCGGCCATCCGTGCCTGCACGACGCGCGAGGCGGCGGCGGAGTCGCGAGAACGCGCCGTCGCCCTCGCGCGCTGG CGCGACGTCCTGGAGGACGGTCTCCACGGGCGCGGCATCGAGACGGTTCCTTCGGATGCCTCCTTCGTCCTGGCCCGTGT CGGCCGTGACGCCCACGCGCAGCTGCGTGCCCGAGGCATCGCCGTACGCCGCTGCGACACGTTCCCCGGACTCGACGCGA GCTGGGTGCGCATCGCCGTGCGCCCACCCGCCACCACCCGCCACCTGCTCGAAGCCCTCGACCACATCCGTGCCCCGCAC CTCACTCACTGA
Upstream 100 bases:
>100_bases TCGCCGACCTCGTCACCGAGATGACGAAGATCAAGCACCCGATGGACGCCGGCCAGAAGGGCCAGAAGGGCATCGAGTGG TGAGGCTGCCCCGCCTCGTG
Downstream 100 bases:
>100_bases CAGGCCCCCGCGCATGCCCTACGTCTCCCCACCTTCCGACATCGCCCGCGACCACGCGACCAAGCGCCTCGCGGCTCTGG CCACCCCACCCGGCGCGCTC
Product: cobyrinic acid a,c-diamide synthase
Products: 2-Oxoglutarate; L-Histidinol phosphate [C]
Alternate protein names: NA
Number of amino acids: Translated: 803; Mature: 802
Protein sequence:
>803_residues MAAPSTGQGKTTVATGLMAALRISGHEVSGHKVGPDYIDPGYHALATGRPGRNLDPHLVGEERIVPLLLHGACGADIAVI EGVMGLYDGRLGTDGFASTAHVATLTRSPVVLVVDVARLSRTAAAIAAGMAAFDDGLEIAGVVLNRTGSAANDAEIVRAM ERTGLPVLGRLPRNEDLATPSRHLGLVPAAERDESAAMLHRLGEQVAEHLDLDAVLTIARAAPELDAEPWEPHAEITAGG DGRPVIAVAGGRAFTFRYAETEELLRAAGCEVVTFDPISDPALPPRTQGIYLGGGFPEVYAAELAANRRLLDDLRAAVDT GVPTVAECAGLLYLAETLDGAPMAAALPFTAAMNERLTLRYPTATAATDSLLTRVGERVTGHEFHRTQISPASSIRPAWT IDGLPTGHATDIVHASYLHVHWAGHPRLAQRFADAAHRAVPHATEPREAVAARDQPATATPRPTEPLRHHGDAETGPDLL DFAVNVYDARRPPWLDHALAMSVAEVQAYPDATPAAAAIAQRHGRKLDEILPTAGAAEAFSLIARLRSWQKPVVIHPQFT EPHAALEQAGHEVTSVLCRPEDGYSLDPAAVPEDADLVIVGNPTNPTGVLHQASTISRLRRKGRLVVVDEAFMDAVPGEA ESLIRERLRDLVVIRSLTKHWSIPGIRAGYVVGHRLVIKHLARRQTPWSVSTPAIAAIRACTTREAAAESRERAVALARW RDVLEDGLHGRGIETVPSDASFVLARVGRDAHAQLRARGIAVRRCDTFPGLDASWVRIAVRPPATTRHLLEALDHIRAPH LTH
Sequences:
>Translated_803_residues MAAPSTGQGKTTVATGLMAALRISGHEVSGHKVGPDYIDPGYHALATGRPGRNLDPHLVGEERIVPLLLHGACGADIAVI EGVMGLYDGRLGTDGFASTAHVATLTRSPVVLVVDVARLSRTAAAIAAGMAAFDDGLEIAGVVLNRTGSAANDAEIVRAM ERTGLPVLGRLPRNEDLATPSRHLGLVPAAERDESAAMLHRLGEQVAEHLDLDAVLTIARAAPELDAEPWEPHAEITAGG DGRPVIAVAGGRAFTFRYAETEELLRAAGCEVVTFDPISDPALPPRTQGIYLGGGFPEVYAAELAANRRLLDDLRAAVDT GVPTVAECAGLLYLAETLDGAPMAAALPFTAAMNERLTLRYPTATAATDSLLTRVGERVTGHEFHRTQISPASSIRPAWT IDGLPTGHATDIVHASYLHVHWAGHPRLAQRFADAAHRAVPHATEPREAVAARDQPATATPRPTEPLRHHGDAETGPDLL DFAVNVYDARRPPWLDHALAMSVAEVQAYPDATPAAAAIAQRHGRKLDEILPTAGAAEAFSLIARLRSWQKPVVIHPQFT EPHAALEQAGHEVTSVLCRPEDGYSLDPAAVPEDADLVIVGNPTNPTGVLHQASTISRLRRKGRLVVVDEAFMDAVPGEA ESLIRERLRDLVVIRSLTKHWSIPGIRAGYVVGHRLVIKHLARRQTPWSVSTPAIAAIRACTTREAAAESRERAVALARW RDVLEDGLHGRGIETVPSDASFVLARVGRDAHAQLRARGIAVRRCDTFPGLDASWVRIAVRPPATTRHLLEALDHIRAPH LTH >Mature_802_residues AAPSTGQGKTTVATGLMAALRISGHEVSGHKVGPDYIDPGYHALATGRPGRNLDPHLVGEERIVPLLLHGACGADIAVIE GVMGLYDGRLGTDGFASTAHVATLTRSPVVLVVDVARLSRTAAAIAAGMAAFDDGLEIAGVVLNRTGSAANDAEIVRAME RTGLPVLGRLPRNEDLATPSRHLGLVPAAERDESAAMLHRLGEQVAEHLDLDAVLTIARAAPELDAEPWEPHAEITAGGD GRPVIAVAGGRAFTFRYAETEELLRAAGCEVVTFDPISDPALPPRTQGIYLGGGFPEVYAAELAANRRLLDDLRAAVDTG VPTVAECAGLLYLAETLDGAPMAAALPFTAAMNERLTLRYPTATAATDSLLTRVGERVTGHEFHRTQISPASSIRPAWTI DGLPTGHATDIVHASYLHVHWAGHPRLAQRFADAAHRAVPHATEPREAVAARDQPATATPRPTEPLRHHGDAETGPDLLD FAVNVYDARRPPWLDHALAMSVAEVQAYPDATPAAAAIAQRHGRKLDEILPTAGAAEAFSLIARLRSWQKPVVIHPQFTE PHAALEQAGHEVTSVLCRPEDGYSLDPAAVPEDADLVIVGNPTNPTGVLHQASTISRLRRKGRLVVVDEAFMDAVPGEAE SLIRERLRDLVVIRSLTKHWSIPGIRAGYVVGHRLVIKHLARRQTPWSVSTPAIAAIRACTTREAAAESRERAVALARWR DVLEDGLHGRGIETVPSDASFVLARVGRDAHAQLRARGIAVRRCDTFPGLDASWVRIAVRPPATTRHLLEALDHIRAPHL TH
Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]
COG id: COG1797
COG function: function code H; Cobyrinic acid a,c-diamide synthase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 GATase cobBQ-type domain [H]
Homologues:
Organism=Escherichia coli, GI1788332, Length=300, Percent_Identity=26, Blast_Score=81, Evalue=3e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002586 - InterPro: IPR004484 - InterPro: IPR017929 - InterPro: IPR011698 [H]
Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]
EC number: 2.6.1.9 [C]
Molecular weight: Translated: 85794; Mature: 85663
Theoretical pI: Translated: 6.60; Mature: 6.60
Prosite motif: PS00105 AA_TRANSFER_CLASS_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAAPSTGQGKTTVATGLMAALRISGHEVSGHKVGPDYIDPGYHALATGRPGRNLDPHLVG CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCC EERIVPLLLHGACGADIAVIEGVMGLYDGRLGTDGFASTAHVATLTRSPVVLVVDVARLS CCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHEECCCCEEEEEEHHHHH RTAAAIAAGMAAFDDGLEIAGVVLNRTGSAANDAEIVRAMERTGLPVLGRLPRNEDLATP HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCC SRHLGLVPAAERDESAAMLHRLGEQVAEHLDLDAVLTIARAAPELDAEPWEPHAEITAGG HHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEECC DGRPVIAVAGGRAFTFRYAETEELLRAAGCEVVTFDPISDPALPPRTQGIYLGGGFPEVY CCCEEEEEECCCEEEEEECCHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEECCCCHHHH AAELAANRRLLDDLRAAVDTGVPTVAECAGLLYLAETLDGAPMAAALPFTAAMNERLTLR HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHCCHHHHCCCCEEEE YPTATAATDSLLTRVGERVTGHEFHRTQISPASSIRPAWTIDGLPTGHATDIVHASYLHV CCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCEEECCCCCCCHHHHEEEEEEEE HWAGHPRLAQRFADAAHRAVPHATEPREAVAARDQPATATPRPTEPLRHHGDAETGPDLL EECCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCHHH DFAVNVYDARRPPWLDHALAMSVAEVQAYPDATPAAAAIAQRHGRKLDEILPTAGAAEAF HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHCCCCCHHHHH SLIARLRSWQKPVVIHPQFTEPHAALEQAGHEVTSVLCRPEDGYSLDPAAVPEDADLVIV HHHHHHHHCCCCEEEECCCCCHHHHHHHCCHHHHHHEECCCCCCCCCCCCCCCCCCEEEE GNPTNPTGVLHQASTISRLRRKGRLVVVDEAFMDAVPGEAESLIRERLRDLVVIRSLTKH CCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH WSIPGIRAGYVVGHRLVIKHLARRQTPWSVSTPAIAAIRACTTREAAAESRERAVALARW CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH RDVLEDGLHGRGIETVPSDASFVLARVGRDAHAQLRARGIAVRRCDTFPGLDASWVRIAV HHHHHCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCEEEEECCCCCCCCCCEEEEEE RPPATTRHLLEALDHIRAPHLTH CCCHHHHHHHHHHHHHCCCCCCC >Mature Secondary Structure AAPSTGQGKTTVATGLMAALRISGHEVSGHKVGPDYIDPGYHALATGRPGRNLDPHLVG CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCC EERIVPLLLHGACGADIAVIEGVMGLYDGRLGTDGFASTAHVATLTRSPVVLVVDVARLS CCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHEECCCCEEEEEEHHHHH RTAAAIAAGMAAFDDGLEIAGVVLNRTGSAANDAEIVRAMERTGLPVLGRLPRNEDLATP HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCC SRHLGLVPAAERDESAAMLHRLGEQVAEHLDLDAVLTIARAAPELDAEPWEPHAEITAGG HHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEECC DGRPVIAVAGGRAFTFRYAETEELLRAAGCEVVTFDPISDPALPPRTQGIYLGGGFPEVY CCCEEEEEECCCEEEEEECCHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEECCCCHHHH AAELAANRRLLDDLRAAVDTGVPTVAECAGLLYLAETLDGAPMAAALPFTAAMNERLTLR HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHCCHHHHCCCCEEEE YPTATAATDSLLTRVGERVTGHEFHRTQISPASSIRPAWTIDGLPTGHATDIVHASYLHV CCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCEEECCCCCCCHHHHEEEEEEEE HWAGHPRLAQRFADAAHRAVPHATEPREAVAARDQPATATPRPTEPLRHHGDAETGPDLL EECCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCHHH DFAVNVYDARRPPWLDHALAMSVAEVQAYPDATPAAAAIAQRHGRKLDEILPTAGAAEAF HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHCCCCCHHHHH SLIARLRSWQKPVVIHPQFTEPHAALEQAGHEVTSVLCRPEDGYSLDPAAVPEDADLVIV HHHHHHHHCCCCEEEECCCCCHHHHHHHCCHHHHHHEECCCCCCCCCCCCCCCCCCEEEE GNPTNPTGVLHQASTISRLRRKGRLVVVDEAFMDAVPGEAESLIRERLRDLVVIRSLTKH CCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH WSIPGIRAGYVVGHRLVIKHLARRQTPWSVSTPAIAAIRACTTREAAAESRERAVALARW CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH RDVLEDGLHGRGIETVPSDASFVLARVGRDAHAQLRARGIAVRRCDTFPGLDASWVRIAV HHHHHCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCEEEEECCCCCCCCCCEEEEEE RPPATTRHLLEALDHIRAPHLTH CCCHHHHHHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: Pyridoxal Phosphate. [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: L-Glutamate; 3-(Imidazol-4-yl)-2-oxopropyl phosphate [C]
Specific reaction: L-Glutamate + 3-(Imidazol-4-yl)-2-oxopropyl phosphate --> 2-Oxoglutarate + L-Histidinol phosphate [C]
General reaction: Amino group transfer [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA