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The map label for this gene is ampH [C]

Identifier: 119716933

GI number: 119716933

Start: 2880242

End: 2881495

Strand: Reverse

Name: ampH [C]

Synonym: Noca_2708

Alternate gene names: 119716933

Gene position: 2881495-2880242 (Counterclockwise)

Preceding gene: 119716934

Following gene: 119716931

Centisome position: 57.79

GC content: 75.2

Gene sequence:

>1254_bases
GTGCGCGACGGCGAGCCGGTGTGGTTCGGCTCGTACGGCGGCCCCGCGGTCCCGGATCACGACCCGGCGGACGTGCAGTA
CCGGATCGGGTCGATCACCAAGACGATGACCGCCGTGCTCGTCCTCCAGCTGGTCCGCGACGGCCGGCTCGGCCTGGACG
AGCCCGCGTCGGCGGTGCTCGACGAGAACGCCGGCCACCCGTATGCCGACCGCACGCTGCGCACCCTGCTCGCGCACGGC
TCCGGGATGCAGTCCGAGCCGGTGGGCTCGTGGTGGGAGCGCACGCCGGGATCCTCGTTCGCCGAGCTGATGGCCGCCAA
CGACGGGTCCGGCGCGGTGTTCGGGGTCCACGAGCGGTTCCACTACTCCAACCTGGGCTACGCCGTCCTCGGCGAGGTCG
CCGCCCGGGCGCTCGGGACCACCTGGTGGGACGCCGTCCGCGACCGGATCCTGGCGCCGCTGGGGATGGCGCGCACGTCG
TACCTCCCCGAGGGCGCCGCGGCGCAGGGCTGGTCGGTCCATCCCTACGACGCCACGCTGCTGGCCGAGCCGGCCACCGA
CAACGGCGCGATGGCCCCGGCCGGGCAGGTGTGGGCGACGGTCACCGACCTCGCGACGTACGCCGCGTTCCTGGCCGGCG
GCCACCCCGACGTGCTCTCCGTCGCCGAGCTCGACCGGGCCTTCGCGCCCCAGGCCGGCAGCCCGGAGGACGGGCTGCGT
TCGGCGCACGGGCTCGGCTTCCAGCTGTTCGCGGGCGGCTCGGGCACGCTGGCCGGGCACACCGGCTCGATGCCCGGTTT
CCTCGCGACCTGCCTGGTCGACCGGCGGCGGCGCACCGGTGGCGTCGTCCTCGCGAACGCGACGACCGGGTTCTCGCCGG
CCGAGGCCGTGATCGGGCTCCTGGAGGAGCTCGAGCGCTGCGAACCGTCCCTGCCCGAGCCGTGGCGGCCCGCCGAGAGC
GTCCCGGCCGAGCTCGCCGGCGTCCCGGGCGTCTGGCACTGGGGCAACACGCCGGTGGTGTTCACGATGGCCGGCAGCGA
GCTGGTGGCACTGCGCAACGGCGTCGAGGCCTACCGGTTCGGCCTGCGCGCCGGCCGGGTGGTCGGGCTGTCCGGCTACC
ACGCCGGCGAGGAGCTGCGGGTCGTGCGTCGATCCGATGGGTCGATCCGCTACCTGGAGGCCGCGACCTTCGTCTACACG
CGGGAGCCCTACGACCCGGAGGCCCCCATCCCTGGGGGCGCTCCGGGTCGCTAG

Upstream 100 bases:

>100_bases
CTTCGCCGAGTGACGGTCACCGACGCGACGGCCCGACGGCTGCTGGCGCGCCTCGCGCGGGCAGTCGACCGGGCGGCTGC
CGTCGGTGGTGGCCGGGTTG

Downstream 100 bases:

>100_bases
TGCCGCTGCTGTGCCGCTGTCTCGGGCCGACGGTCAGACCGTGGACTCCTTGGTGACCTGCAGGTCGTAGACGAACGCCG
GGCCGCACTCCAGCGGTGCA

Product: beta-lactamase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MRDGEPVWFGSYGGPAVPDHDPADVQYRIGSITKTMTAVLVLQLVRDGRLGLDEPASAVLDENAGHPYADRTLRTLLAHG
SGMQSEPVGSWWERTPGSSFAELMAANDGSGAVFGVHERFHYSNLGYAVLGEVAARALGTTWWDAVRDRILAPLGMARTS
YLPEGAAAQGWSVHPYDATLLAEPATDNGAMAPAGQVWATVTDLATYAAFLAGGHPDVLSVAELDRAFAPQAGSPEDGLR
SAHGLGFQLFAGGSGTLAGHTGSMPGFLATCLVDRRRRTGGVVLANATTGFSPAEAVIGLLEELERCEPSLPEPWRPAES
VPAELAGVPGVWHWGNTPVVFTMAGSELVALRNGVEAYRFGLRAGRVVGLSGYHAGEELRVVRRSDGSIRYLEAATFVYT
REPYDPEAPIPGGAPGR

Sequences:

>Translated_417_residues
MRDGEPVWFGSYGGPAVPDHDPADVQYRIGSITKTMTAVLVLQLVRDGRLGLDEPASAVLDENAGHPYADRTLRTLLAHG
SGMQSEPVGSWWERTPGSSFAELMAANDGSGAVFGVHERFHYSNLGYAVLGEVAARALGTTWWDAVRDRILAPLGMARTS
YLPEGAAAQGWSVHPYDATLLAEPATDNGAMAPAGQVWATVTDLATYAAFLAGGHPDVLSVAELDRAFAPQAGSPEDGLR
SAHGLGFQLFAGGSGTLAGHTGSMPGFLATCLVDRRRRTGGVVLANATTGFSPAEAVIGLLEELERCEPSLPEPWRPAES
VPAELAGVPGVWHWGNTPVVFTMAGSELVALRNGVEAYRFGLRAGRVVGLSGYHAGEELRVVRRSDGSIRYLEAATFVYT
REPYDPEAPIPGGAPGR
>Mature_417_residues
MRDGEPVWFGSYGGPAVPDHDPADVQYRIGSITKTMTAVLVLQLVRDGRLGLDEPASAVLDENAGHPYADRTLRTLLAHG
SGMQSEPVGSWWERTPGSSFAELMAANDGSGAVFGVHERFHYSNLGYAVLGEVAARALGTTWWDAVRDRILAPLGMARTS
YLPEGAAAQGWSVHPYDATLLAEPATDNGAMAPAGQVWATVTDLATYAAFLAGGHPDVLSVAELDRAFAPQAGSPEDGLR
SAHGLGFQLFAGGSGTLAGHTGSMPGFLATCLVDRRRRTGGVVLANATTGFSPAEAVIGLLEELERCEPSLPEPWRPAES
VPAELAGVPGVWHWGNTPVVFTMAGSELVALRNGVEAYRFGLRAGRVVGLSGYHAGEELRVVRRSDGSIRYLEAATFVYT
REPYDPEAPIPGGAPGR

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 44058; Mature: 44058

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDGEPVWFGSYGGPAVPDHDPADVQYRIGSITKTMTAVLVLQLVRDGRLGLDEPASAVL
CCCCCEEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
DENAGHPYADRTLRTLLAHGSGMQSEPVGSWWERTPGSSFAELMAANDGSGAVFGVHERF
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHCCCCCCCEEEEHHHH
HYSNLGYAVLGEVAARALGTTWWDAVRDRILAPLGMARTSYLPEGAAAQGWSVHPYDATL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCEE
LAEPATDNGAMAPAGQVWATVTDLATYAAFLAGGHPDVLSVAELDRAFAPQAGSPEDGLR
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHH
SAHGLGFQLFAGGSGTLAGHTGSMPGFLATCLVDRRRRTGGVVLANATTGFSPAEAVIGL
HHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
LEELERCEPSLPEPWRPAESVPAELAGVPGVWHWGNTPVVFTMAGSELVALRNGVEAYRF
HHHHHHCCCCCCCCCCCHHHCCHHHCCCCCEEECCCCCEEEEECCCEEEHHHCCHHHHHH
GLRAGRVVGLSGYHAGEELRVVRRSDGSIRYLEAATFVYTREPYDPEAPIPGGAPGR
HHCCCCEEEECCCCCCCCEEEEECCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRDGEPVWFGSYGGPAVPDHDPADVQYRIGSITKTMTAVLVLQLVRDGRLGLDEPASAVL
CCCCCEEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
DENAGHPYADRTLRTLLAHGSGMQSEPVGSWWERTPGSSFAELMAANDGSGAVFGVHERF
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHCCCCCCCEEEEHHHH
HYSNLGYAVLGEVAARALGTTWWDAVRDRILAPLGMARTSYLPEGAAAQGWSVHPYDATL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCEE
LAEPATDNGAMAPAGQVWATVTDLATYAAFLAGGHPDVLSVAELDRAFAPQAGSPEDGLR
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHH
SAHGLGFQLFAGGSGTLAGHTGSMPGFLATCLVDRRRRTGGVVLANATTGFSPAEAVIGL
HHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
LEELERCEPSLPEPWRPAESVPAELAGVPGVWHWGNTPVVFTMAGSELVALRNGVEAYRF
HHHHHHCCCCCCCCCCCHHHCCHHHCCCCCEEECCCCCEEEEECCCEEEHHHCCHHHHHH
GLRAGRVVGLSGYHAGEELRVVRRSDGSIRYLEAATFVYTREPYDPEAPIPGGAPGR
HHCCCCEEEECCCCCCCCEEEEECCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]