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The map label for this gene is murA [H]

Identifier: 119716897

GI number: 119716897

Start: 2842507

End: 2844033

Strand: Reverse

Name: murA [H]

Synonym: Noca_2672

Alternate gene names: 119716897

Gene position: 2844033-2842507 (Counterclockwise)

Preceding gene: 119716901

Following gene: 119716896

Centisome position: 57.04

GC content: 68.83

Gene sequence:

>1527_bases
ATGAGCGAGGGATACAAGAACCGCATCGGGAACCTCATTCGTGATGCCCGCAAGCACCGGGGCCTGACCCAGCACCAGCT
CGCGGACCTGCTCGGCACCAGCCAGAGCGCGATCAACCGGATCGAGAAGGGGCACCAGAACCTCTCCCTGGAGATGCTCG
CCCGGATCGGTGCCGCGCTCGACTCCGAGATCGTGGCCCTCGGCGCCGGGCCCACCCACCTGCGGGTGAACGGCCCGACC
ACGCTGTCCGGCGAGATCGACGTCAAGACCTCCAAGAACGCCGGGGTCGCGCTGCTGTGCGCCACCCTGCTGAACCGGGG
GCGCACCACGCTGCGCAAGGTCGCCCGGATCGAGGAGGTCAACCGGCTGCTCGAGGTGCTGACCAGCATGGGCGTGCAGT
GCCGCTGGCTCAACGACGACAACGACCTCGAGATCGTGCCCCCGCGGACCCTCGAGCTGGACCACATCGACGCCGACTCG
GCGCGCCGCACCCGCTCGATCATCATGTTCCTGGGCCCGCTGTTGCACCGCGCGGACGCCTTCGAGCTGCCGTACGCCGG
CGGCTGCGACCTCGGCACCCGCACCGTCGAGCCGCACATGGCGGCGCTGCGGCCCTTCGGCCTGGAGGTGAAGGCCACCG
AGGGCAACTACCACGCGGCGGTCAACCACGCGGTCGAGCCCGGACGCCCGATCGTGCTCACCGAGCGCGGCGACACCGTG
ACCGAGAACGCCCTGATGGCGGCGGCGCTGCACCCCGGCACCACCGTGATCCGCAACGCCTCGTCGAACTACATGGTCCA
GGACCTGTGCTTCTACCTCGAGCGGCTCGGCGTGCGCATCGAGGGCATCGGCACCACGACGCTCGCGGTCACCGGCCTCG
CCGAGATCGATGTGGACGTCGACTACGCGCCCAGCGAGGACCCGATCGAGGCGATGTCGCTGCTGGCCGCCGCGATCGTC
ACGAAGTCCTCGATCACGATCCGCCGGGTGCCGATCGAGTTCCTCGAGATCGAGCTGGCCCTGTTGGAGGAGATGGGCTT
CTGCTACGACCGCTCCGCGGAGTACGTCGCGCTCAACGGCCACACGCGACTGGTCGACATCACCACGCGGCCCTCCGAGC
TGCACGCGCCGCTCGACAAGATCCACCCGATGCCGTTCCCCGGCCTGAACATCGACAACCTGCCGTTCTTCGCGGTCATC
GCCGCCGTTGCCCAGGGCCAGACCCTGCTGCACGACTGGGTCTACGAGAACCGGGCGATCTACCTCACCGACCTGAACAA
GCTCGGGGCGAAGGTGAAGCTCCTCGACCCGCACCGGGTGATGATCGAGGGTCCGACGAGCTTCACCGGCACCGAGCTCG
TCTGCCCGCCGGCGCTGCGCCCCGCGGTCGTCATCCTGCTGGCGATGCTCGCCTCGAAGGGCACCTCGGTGCTGCGCTCG
ACGTACGTCATCCACCGCGGCTACGAGGACCTCGCCGAGCGCCTCAACCAGCTCGGCGCCACCATCGAGACGTTCCGAGA
CATCTAG

Upstream 100 bases:

>100_bases
CACGCATGCCAGCATCTTGTCAGCCGGCCCTCCCCCGGCCGCCCCGGGCGCCGGACGGGCTGGTTGTGGCGTTATCTCAT
ATGTGAGTTACCGTGGCGGT

Downstream 100 bases:

>100_bases
CGAGCTGGATCAGCGCCACTTCGGCACGCAGGCCCAGAGCCTCGCGGCTACTCGAAGAGCGTCTCCACCCAGGCCCGCGG
TGAGGGCTTGCCGACGGGCG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MSEGYKNRIGNLIRDARKHRGLTQHQLADLLGTSQSAINRIEKGHQNLSLEMLARIGAALDSEIVALGAGPTHLRVNGPT
TLSGEIDVKTSKNAGVALLCATLLNRGRTTLRKVARIEEVNRLLEVLTSMGVQCRWLNDDNDLEIVPPRTLELDHIDADS
ARRTRSIIMFLGPLLHRADAFELPYAGGCDLGTRTVEPHMAALRPFGLEVKATEGNYHAAVNHAVEPGRPIVLTERGDTV
TENALMAAALHPGTTVIRNASSNYMVQDLCFYLERLGVRIEGIGTTTLAVTGLAEIDVDVDYAPSEDPIEAMSLLAAAIV
TKSSITIRRVPIEFLEIELALLEEMGFCYDRSAEYVALNGHTRLVDITTRPSELHAPLDKIHPMPFPGLNIDNLPFFAVI
AAVAQGQTLLHDWVYENRAIYLTDLNKLGAKVKLLDPHRVMIEGPTSFTGTELVCPPALRPAVVILLAMLASKGTSVLRS
TYVIHRGYEDLAERLNQLGATIETFRDI

Sequences:

>Translated_508_residues
MSEGYKNRIGNLIRDARKHRGLTQHQLADLLGTSQSAINRIEKGHQNLSLEMLARIGAALDSEIVALGAGPTHLRVNGPT
TLSGEIDVKTSKNAGVALLCATLLNRGRTTLRKVARIEEVNRLLEVLTSMGVQCRWLNDDNDLEIVPPRTLELDHIDADS
ARRTRSIIMFLGPLLHRADAFELPYAGGCDLGTRTVEPHMAALRPFGLEVKATEGNYHAAVNHAVEPGRPIVLTERGDTV
TENALMAAALHPGTTVIRNASSNYMVQDLCFYLERLGVRIEGIGTTTLAVTGLAEIDVDVDYAPSEDPIEAMSLLAAAIV
TKSSITIRRVPIEFLEIELALLEEMGFCYDRSAEYVALNGHTRLVDITTRPSELHAPLDKIHPMPFPGLNIDNLPFFAVI
AAVAQGQTLLHDWVYENRAIYLTDLNKLGAKVKLLDPHRVMIEGPTSFTGTELVCPPALRPAVVILLAMLASKGTSVLRS
TYVIHRGYEDLAERLNQLGATIETFRDI
>Mature_507_residues
SEGYKNRIGNLIRDARKHRGLTQHQLADLLGTSQSAINRIEKGHQNLSLEMLARIGAALDSEIVALGAGPTHLRVNGPTT
LSGEIDVKTSKNAGVALLCATLLNRGRTTLRKVARIEEVNRLLEVLTSMGVQCRWLNDDNDLEIVPPRTLELDHIDADSA
RRTRSIIMFLGPLLHRADAFELPYAGGCDLGTRTVEPHMAALRPFGLEVKATEGNYHAAVNHAVEPGRPIVLTERGDTVT
ENALMAAALHPGTTVIRNASSNYMVQDLCFYLERLGVRIEGIGTTTLAVTGLAEIDVDVDYAPSEDPIEAMSLLAAAIVT
KSSITIRRVPIEFLEIELALLEEMGFCYDRSAEYVALNGHTRLVDITTRPSELHAPLDKIHPMPFPGLNIDNLPFFAVIA
AVAQGQTLLHDWVYENRAIYLTDLNKLGAKVKLLDPHRVMIEGPTSFTGTELVCPPALRPAVVILLAMLASKGTSVLRST
YVIHRGYEDLAERLNQLGATIETFRDI

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=433, Percent_Identity=27.7136258660508, Blast_Score=169, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 55627; Mature: 55496

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50943 HTH_CROC1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEGYKNRIGNLIRDARKHRGLTQHQLADLLGTSQSAINRIEKGHQNLSLEMLARIGAAL
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHC
DSEIVALGAGPTHLRVNGPTTLSGEIDVKTSKNAGVALLCATLLNRGRTTLRKVARIEEV
CCCEEEECCCCCEEEECCCEEECCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
NRLLEVLTSMGVQCRWLNDDNDLEIVPPRTLELDHIDADSARRTRSIIMFLGPLLHRADA
HHHHHHHHHCCCEEEEECCCCCEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
FELPYAGGCDLGTRTVEPHMAALRPFGLEVKATEGNYHAAVNHAVEPGRPIVLTERGDTV
CCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCEEEECCCCCC
TENALMAAALHPGTTVIRNASSNYMVQDLCFYLERLGVRIEGIGTTTLAVTGLAEIDVDV
HHHHHEEEEECCCCCEEECCCCCHHHHHHHHHHHHHCEEEEECCCEEEEEEEEEEEEEEE
DYAPSEDPIEAMSLLAAAIVTKSSITIRRVPIEFLEIELALLEEMGFCYDRSAEYVALNG
CCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCEEEECC
HTRLVDITTRPSELHAPLDKIHPMPFPGLNIDNLPFFAVIAAVAQGQTLLHDWVYENRAI
CEEEEEEECCCHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCEE
YLTDLNKLGAKVKLLDPHRVMIEGPTSFTGTELVCPPALRPAVVILLAMLASKGTSVLRS
EEEEHHHHCCEEEEECCCEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHCCCHHHHHH
TYVIHRGYEDLAERLNQLGATIETFRDI
HHHHCCCHHHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
SEGYKNRIGNLIRDARKHRGLTQHQLADLLGTSQSAINRIEKGHQNLSLEMLARIGAAL
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHC
DSEIVALGAGPTHLRVNGPTTLSGEIDVKTSKNAGVALLCATLLNRGRTTLRKVARIEEV
CCCEEEECCCCCEEEECCCEEECCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
NRLLEVLTSMGVQCRWLNDDNDLEIVPPRTLELDHIDADSARRTRSIIMFLGPLLHRADA
HHHHHHHHHCCCEEEEECCCCCEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
FELPYAGGCDLGTRTVEPHMAALRPFGLEVKATEGNYHAAVNHAVEPGRPIVLTERGDTV
CCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCEEEECCCCCC
TENALMAAALHPGTTVIRNASSNYMVQDLCFYLERLGVRIEGIGTTTLAVTGLAEIDVDV
HHHHHEEEEECCCCCEEECCCCCHHHHHHHHHHHHHCEEEEECCCEEEEEEEEEEEEEEE
DYAPSEDPIEAMSLLAAAIVTKSSITIRRVPIEFLEIELALLEEMGFCYDRSAEYVALNG
CCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCEEEECC
HTRLVDITTRPSELHAPLDKIHPMPFPGLNIDNLPFFAVIAAVAQGQTLLHDWVYENRAI
CEEEEEEECCCHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCEE
YLTDLNKLGAKVKLLDPHRVMIEGPTSFTGTELVCPPALRPAVVILLAMLASKGTSVLRS
EEEEHHHHCCEEEEECCCEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHCCCHHHHHH
TYVIHRGYEDLAERLNQLGATIETFRDI
HHHHCCCHHHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]